Protein kinase G phosphorylates soluble guanylyl cyclase on serine 64 and inhibits its activity

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 28, Issue 10, 2008, Pages 1803-1810

  Zhou, Zongmin ^a   Sayed, Nazish ^b   Pyriochou, Anastasia ^a,c   Roussos, Charis ^a   Fulton, David ^d   Beuve, Annie ^b   Papapetropoulos, Andreas ^a,c  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^b RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF PATRAS   (Greece)

^d MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

cGMP; Nitric oxide; Phosphorylation; PKG; Soluble guanylyl cyclase

Indexed keywords

CYCLIC GMP DEPENDENT PROTEIN KINASE; GUANYLATE CYCLASE; NITRIC OXIDE; SERINE; ACTIN BINDING PROTEIN; CELL ADHESION MOLECULE; CELL RECEPTOR; CYCLIC GMP; HYBRID PROTEIN; PEPTIDE FRAGMENT; PHOSPHOPROTEIN; SOLUBLE GUANYLYL CYCLASE; VASODILATOR STIMULATED PHOSPHOPROTEIN; VASODILATOR-STIMULATED PHOSPHOPROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; IMMUNOPRECIPITATION; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING; ANIMAL; CELL STRAIN COS1; CERCOPITHECUS; DRUG ANTAGONISM; ENZYME SPECIFICITY; FEEDBACK SYSTEM; GENETIC TRANSFECTION; GENETICS; KINETICS; METABOLISM; MUTATION; PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CELL ADHESION MOLECULES; CERCOPITHECUS AETHIOPS; COS CELLS; CYCLIC GMP; CYCLIC GMP-DEPENDENT PROTEIN KINASES; FEEDBACK, BIOCHEMICAL; GUANYLATE CYCLASE; KINETICS; MICROFILAMENT PROTEINS; MUTATION; NITRIC OXIDE; PEPTIDE FRAGMENTS; PHOSPHOPROTEINS; PHOSPHORYLATION; RATS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECOMBINANT FUSION PROTEINS; SERINE; SIGNAL TRANSDUCTION; SUBSTRATE SPECIFICITY; TRANSFECTION;

EID: 53449094062     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.108.165043     Document Type: Article

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