Cysteine 149 in the extracellular finger domain of acid-sensing ion channel 1b subunit is critical for zinc-mediated inhibition

Neuroscience

Volumn 193, Issue , 2011, Pages 89-99

  Jiang, Q ^a   Inoue, K ^b   Wu, X ^c   Papasian, C J ^a   Wang, J Q ^a   Xiong, Z G ^d   Chu, X P ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY SCHOOL OF MEDICINE   (United States)

^b HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c OHIO STATE UNIVERSITY   (United States)

^d MOREHOUSE SCHOOL OF MEDICINE   (United States)

Author keywords

Acid sensing ion channels; ASIC1b; Patch clamp; Zinc

Indexed keywords

ACID SENSING ION CHANNEL; ACID SENSING ION CHANNEL SUBUNIT 1B; AMINO ACID; CYSTEINE; HISTIDINE; UNCLASSIFIED DRUG; ZINC;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHO CELL; CONCENTRATION RESPONSE; ELECTRIC POTENTIAL; EXTRACELLULAR CALCIUM; IC 50; ION CURRENT; MUTAGENESIS; NONHUMAN; PATCH CLAMP; PH MEASUREMENT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; WHOLE CELL;

ANALYSIS OF VARIANCE; ANIMALS; CALCIUM; CELL LINE, TRANSFORMED; CRICETINAE; CRICETULUS; CYSTEINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHYL METHANESULFONATE; EXTRACELLULAR FLUID; HYDROGEN PEROXIDE; MEMBRANE POTENTIALS; MUTAGENESIS, SITE-DIRECTED; NERVE TISSUE PROTEINS; PATCH-CLAMP TECHNIQUES; PROTEIN STRUCTURE, TERTIARY; RATS; SODIUM CHANNELS; TRACE ELEMENTS; TRANSFECTION; ZINC;

EID: 80052476803     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2011.07.021     Document Type: Article

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