-
1
-
-
7244245762
-
International H 1 human Genome Sequencing Consortium finishing the euchromatic sequence of the human genome
-
International H 1. uman Genome Sequencing Consortium. Finishing the euchromatic sequence of the human genome. Nature 2004;431:931-45.
-
(2004)
Nature
, vol.431
, pp. 931-945
-
-
-
2
-
-
33646799069
-
Global and regional burden of disease and risk factors 2001: Systematic analysis of population health data
-
L opez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJ. Global and regional burden of disease and risk factors, 2001: Systematic analysis of population health data. Lancet 2006;367:1747-57.
-
Lancet
, vol.2006
, Issue.367
, pp. 1747-1757
-
-
Lopez, A.D.1
Mathers, C.D.2
Ezzati, M.3
Jamison, D.T.4
Murray, C.J.5
-
3
-
-
0022630290
-
A prospective study of parental history of myocardial infarction and coronary heart disease in women
-
C olditz GA, Stampfer MJ, Willett W, Rosner B, Spizer FE, Hennkens CH. A prospective study of parental history of myocardial infarction and coronary heart disease in women. Am J Epidemiol 1986;123:48-58.
-
(1986)
Am. J. Epidemiol
, vol.123
, pp. 48-58
-
-
Colditz, G.A.1
Stampfer, M.J.2
Willett, W.3
Rosner, B.4
Spizer, F.E.5
Hennkens, C.H.6
-
5
-
-
18944398818
-
The molecular genetics of coronary artery and myocardial infarction
-
S hen G, Archacki SR, Wang Q. Th e molecular genetics of coronary artery and myocardial infarction. Acute Coronary Syndromes 2004;6:129-41.
-
(2004)
Acute Coronary Syndromes
, vol.6
, pp. 129-141
-
-
Shen, G.1
Archacki, S.R.2
Wang, Q.3
-
6
-
-
0024417535
-
Coronary risk associated with age and sex of parental heart disease in framingham study
-
S childkraut JM, Myers RH, Cupples LA, Dan K, Kiel MA, William BK. Coronary risk associated with age and sex of parental heart disease in Framingham Study. Am J Cardiol. 1989;64:555-9.
-
(1989)
Am. J. Cardiol.
, vol.64
, pp. 555-559
-
-
Schildkraut, J.M.1
Myers, R.H.2
Cupples, L.A.3
Dan, K.4
Kiel, M.A.5
William, B.K.6
-
8
-
-
0031001720
-
Alternative projections of mortality and disability by cause 1990-2020: Global burden of disease study
-
Murray CJL, Lopez AD. Alternative projections of mortality and disability by cause 1990 - 2020: Global burden of disease study. Lancet 1997;1498-504.
-
Lancet
, vol.1997
, pp. 1498-1504
-
-
Murray, C.J.L.1
Lopez, A.D.2
-
9
-
-
18944399174
-
Molecular genetics of coronary artery disease
-
Q ing W. Molecular genetics of coronary artery disease. Curr Opin Cardiol. 2005;20:182-8.
-
(2005)
Curr. Opin. Cardiol.
, vol.20
, pp. 182-188
-
-
Qing, W.1
-
10
-
-
34848815115
-
Mechanisms of disease: The genetic basis of coronary heart disease
-
K ullo IJ, Ding K. Mechanisms of disease: the genetic basis of coronary heart disease. Nat Clin Pract Cardiovasc Med;4:558-69.
-
Nat. Clin. Pract Cardiovasc Med
, vol.4
, pp. 558-569
-
-
Kullo, I.J.1
Ding, K.2
-
11
-
-
33749018788
-
Genetic susceptibility to myocardial infarction and coronary artery disease
-
T opol EJ, Smith J, Plow EF, Wang QK. Genetic susceptibility to myocardial infarction and coronary artery disease. Hum Mol Genet;15:R117- 23.
-
Hum. Mol. Genet
, vol.15
-
-
Topol, E.J.1
Smith, J.2
Plow, E.F.3
Wang, Q.K.4
-
12
-
-
39549093148
-
General cardiovascular risk profi le for use in primary care: The framingham heart study
-
Epub 2008 Jan 22
-
D'Agostino RB Sr, Vasan RS, Pencina MJ, Wolf PA, Cobain M, Massaro JM., et al. General cardiovascular risk profi le for use in primary care: Th e Framingham Heart Study. Circulation 2008;117:743-53. Epub 2008 Jan 22.
-
(2008)
Circulation
, vol.117
, pp. 743-753
-
-
D'Agostino, Sr.R.B.1
Vasan, R.S.2
Pencina, M.J.3
Wolf, P.A.4
Cobain, M.5
Massaro, J.M.6
-
13
-
-
47649099448
-
Discriminatory accuracy from single-nucleotide polymorphisms in models to predict breast cancer risk
-
G ail MH. Discriminatory accuracy from single-nucleotide polymorphisms in models to predict breast cancer risk. J Natl Cancer Inst. 2008;100:1037-41.
-
(2008)
J. Natl. Cancer Inst.
, vol.100
, pp. 1037-1041
-
-
Gail, M.H.1
-
14
-
-
57649243614
-
Genome-based prediction of common diseases: Advances and prospects
-
J anssens AC, van Duijn CM. Genome-based prediction of common diseases: Advances and prospects. Hum Mol Genet. 2008;17:166-73.
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 166-173
-
-
Janssens, A.C.1
Van Duijn, C.M.2
-
15
-
-
0037078968
-
C-reactive protein- t o screen or not to screen
-
M osca L. C-reactive protein- t o screen or not to screen? N Engl J Med. 2002;20:1615-7.
-
(2002)
N. Engl. J. Med.
, vol.20
, pp. 1615-1617
-
-
Mosca, L.1
-
16
-
-
0142120730
-
Novel risk markers and clinical practice
-
M anolio T. Novel risk markers and clinical practice. N Engl J Med. 2003;17:1587-9.
-
(2003)
N. Engl. J. Med.
, vol.17
, pp. 1587-1589
-
-
Manolio, T.1
-
17
-
-
34249906772
-
Relevance of genetics and genomics for prevention and treatment of cardiovascular disease: A scientific statement from the American Heart Association Council on Epidemiology and Prevention
-
American Heart Association Council on Epidemiology and Prevention American Heart Association Stroke Council Functional Genomics and Translational Working Group the Stroke Council, and the Functional Genomics and Translational Biology Interdisciplinary Working Group
-
Arnett DK, Baird AE, Barkley RA, Basson CT, Boerwinkle E, Ganesh SK., et al. American Heart Association Council on Epidemiology and Prevention; American Heart Association Stroke Council; Functional Genomics and Translational Working Group. Relevance of genetics and genomics for prevention and treatment of cardiovascular disease: A scientifi c statement from the American Heart Association Council on Epidemiology and Prevention, the Stroke Council, and the Functional Genomics and Translational Biology Interdisciplinary Working Group. Circulation;115:2878-901.
-
Circulation
, vol.115
, pp. 2878-901
-
-
Arnett, D.K.1
Baird, A.E.2
Barkley, R.A.3
Basson, C.T.4
Boerwinkle, E.5
Ganesh, S.K.6
-
18
-
-
18544372620
-
Comprehensive linkage analysis for myocardial infarction and its related risk factors
-
B roeckel U, Hengstenberg C, Mayer B, Holmer S, Martin LJ, Comuzzie AG., et al. comprehensive linkage analysis for myocardial infarction and its related risk factors. Nat Genet. 30:210-4.
-
Nat. Genet.
, vol.30
, pp. 210-214
-
-
Broeckel, U.1
Hengstenberg, C.2
Mayer, B.3
Holmer, S.4
Martin, L.J.5
Comuzzie, A.G.6
-
19
-
-
29444444748
-
A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity specifi c risk of myocardial infarction
-
H elgadottir A, Manolescu A, Helgason A, Th orleifsson G, Th orsteinsdottir U. A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity specifi c risk of myocardial infarction. Nat Genet 2006;38:68-74.
-
(2006)
Nat. Genet
, vol.38
, pp. 68-74
-
-
Helgadottir, A.1
Manolescu, A.2
Helgason, A.3
Thorleifsson, G.4
Thorsteinsdottir, U.5
-
20
-
-
34249996115
-
A common allele on chromosome 9 associated with coronary heart disease
-
M cPherson R, Pertsemlidis A, Kavaslar N, Stewart A, Roberts R., et al. A common allele on chromosome 9 associated with coronary heart disease. Science 2007;316:1488-91.
-
(2007)
Science
, vol.316
, pp. 1488-1491
-
-
Mc Pherson, R.1
Pertsemlidis, A.2
Kavaslar, N.3
Stewart, A.4
Roberts, R.5
-
21
-
-
34250010480
-
A common variant on chromosome 9p21 aff ects the risk of myocardial infarction
-
H elgadottir A, Th orleifsson G, Manolescu A, Gretarsdottir S, Blondal T. A common variant on chromosome 9p21 aff ects the risk of myocardial infarction. Science;316:1491-3.
-
Science
, vol.316
, pp. 1491-1493
-
-
Helgadottir, A.1
Thorleifsson, G.2
Manolescu, A.3
Gretarsdottir, S.4
Blondal, T.5
-
22
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
Wellcome Trust Case Control Consortium
-
W ellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature ;447:661-78.
-
Nature
, vol.447
, pp. 661-678
-
-
-
23
-
-
34547623750
-
WTCCC and the Cardiogenics Consortium. Genomewide association analysis of coronary artery disease
-
S amani NJ, Erdmann J, Hall AS, Hengstenberg C, Mangino M, Mayer B., et al. WTCCC and the Cardiogenics Consortium. Genomewide association analysis of coronary artery disease. N Engl J Med. 2007;357:443-53.
-
(2007)
N. Engl. J. Med.
, vol.357
, pp. 443-453
-
-
Samani, N.J.1
Erdmann, J.2
Hall, A.S.3
Hengstenberg, C.4
Mangino, M.5
Mayer, B.6
-
24
-
-
34249885875
-
A genomewide association study of type 2 diabetes in Finns detects multiple susceptibility variants
-
S cott LJ, Mohlke KL, Bonnycastle LL, Willer CJ, Li Y, Duren WL., et al. A genomewide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 2007;316:1341-5.
-
(2007)
Science
, vol.316
, pp. 1341-1345
-
-
Scott, L.J.1
Mohlke, K.L.2
Bonnycastle, L.L.3
Willer, C.J.4
Li, Y.5
Duren, W.L.6
-
25
-
-
34249888775
-
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
-
Saxena R, Voight BF, Lyssenko V, Burtt NP, de Bakker PI, Chen H., et al. Genome-wide association analysis identifi es loci for type 2 diabetes and triglyceride levels. Science 2007;316:1331-6.
-
(2007)
Science
, vol.316
, pp. 1331-1336
-
-
Saxena, R.1
Voight, B.F.2
Lyssenko, V.3
Burtt, N.P.4
De Bakker, P.I.5
Chen, H.6
-
26
-
-
41649085340
-
Cardiogenics Consortium.repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and coronary artery disease
-
Schunkert H, Gótz A, Braund P, McGinnis R, Tregouet DA, Mangino M., et al., Cardiogenics Consortium. Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and coronary artery disease. Circulation 2008;117:1675-84.
-
(2008)
Circulation
, vol.117
, pp. 1675-1684
-
-
Schunkert, H.1
Gótz, A.2
Braund, P.3
Mc Ginnis, R.4
Tregouet, D.A.5
Mangino, M.6
-
27
-
-
40549109924
-
Procardis Consortium susceptibility to coronary artery disease and diabetes is encoded by distinct tightly linked SNPs in the ANRIL locus on chromosome 9p
-
B roadbent HM, Peden JF, Lorkowski S, Goel A, Ongen H, Green F., et al., PROCARDIS Consortium. Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p. Hum Mol Genet 2008;17:806-14.
-
(2008)
Hum. Mol. Genet
, vol.17
, pp. 806-814
-
-
Broadbent, H.M.1
Peden, J.F.2
Lorkowski, S.3
Goel, A.4
Ongen, H.5
Green, F.6
-
28
-
-
70349569056
-
Functional analysis of the chromosome 9p21.3 coronary artery disease risk locus
-
Jarinova O, Stewart AF, Roberts R, Wells G, Lau P, Naing T., et al. Functional analysis of the chromosome 9p21.3 coronary artery disease risk locus. Arterioscler Th romb Vasc Biol. 2009;29:1671-7.
-
(2009)
Arterioscler Thromb. Vasc Biol.
, vol.29
, pp. 1671-1677
-
-
Jarinova, O.1
Stewart, A.F.2
Roberts, R.3
Wells, G.4
Lau, P.5
Naing, T.6
-
29
-
-
77649166974
-
Anril expression is associated with atherosclerosis risk at chromosome 9p21
-
H oldt LM, Beutner F, Scholz M, Gielen S, Gäbel G, Bergert H., et al. ANRIL expression is associated with atherosclerosis risk at chromosome 9p21. Arterioscler Th romb Vasc Biol. 2010;30:620-7.
-
Arterioscler Thromb. Vasc. Biol.
, vol.2010
, Issue.30
, pp. 620-627
-
-
Holdt, L.M.1
Beutner, F.2
Scholz, M.3
Gielen, S.4
Gäbel, G.5
Bergert, H.6
-
30
-
-
18744407845
-
Functional SNPs in the lymphotoxin-á gene that are associated with susceptibility to myocardial infarction
-
Ozaki K, Ohnishi Y, Iida A, Sekine A, Yamada R, Tsunoda T., et al. Functional SNPs in the lymphotoxin- á gene that are associated with susceptibility to myocardial infarction. Nat Genet. 2002;32:650-4.
-
(2002)
Nat. Genet.
, vol.32
, pp. 650-654
-
-
Ozaki, K.1
Ohnishi, Y.2
Iida, A.3
Sekine, A.4
Yamada, R.5
Tsunoda, T.6
-
31
-
-
2342480580
-
Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin - A secretion in vitro
-
O zaki K, Inoue K, Sato H, Iida A, Ohnishi Y, Sekine A., et al. Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin- á secretion in vitro. Nature 2004;429:72-5.
-
(2004)
Nature
, vol.429
, pp. 72-75
-
-
Ozaki, K.1
Inoue, K.2
Sato, H.3
Iida, A.4
Ohnishi, Y.5
Sekine, A.6
-
32
-
-
33746555366
-
A functional SNP in PSMA6 confers risk of myocardial infarction in the Japanese population
-
Ozaki K, Sato H, Iida A, Mizuno H, Nakamura T, Miyamoto Y., et al. A functional SNP in PSMA6 confers risk of myocardial infarction in the Japanese population. Nat Genet. 2006;38:921-5.
-
(2006)
Nat Genet.
, vol.38
, pp. 921-925
-
-
Ozaki, K.1
Sato, H.2
Iida, A.3
Mizuno, H.4
Nakamura, T.5
Miyamoto, Y.6
-
33
-
-
61349108698
-
SNPs in BRAP associated with risk of myocardial infarction in Asian populations
-
O zaki K, Sato H, Inoue K, Tsunoda T, Sakata Y, Mizuno H., et al. SNPs in BRAP associated with risk of myocardial infarction in Asian populations. Nat Genet. 2009;41:329-933.
-
(2009)
Nat. Genet.
, vol.4
, pp. 329-933
-
-
Ozaki, K.1
Sato, H.2
Inoue, K.3
Tsunoda, T.4
Sakata, Y.5
Mizuno, H.6
-
34
-
-
33746597102
-
International Study of Infarct Survival (ISIS) Collaborators lymphotoxin-alpha gene and risk of myocardial infarction in 6928 cases and 2712 controls in the ISIS case-control study
-
C larke R, Xu P, Bennett D, Lewington S, Zondervan K, Parish S., et al., International Study of Infarct Survival (ISIS) Collaborators. Lymphotoxin-alpha gene and risk of myocardial infarction in 6,928 cases and 2,712 controls in the ISIS case-control study. PLoS Genet. 2006;2:e107.
-
(2006)
PLoS Genet.
, vol.2
-
-
Clarke, R.1
Xu, P.2
Bennett, D.3
Lewington, S.4
Zondervan, K.5
Parish, S.6
-
35
-
-
38649125868
-
Newly identified loci that influence lipid concentrations and risk of coronary artery disease
-
W iller CJ, Sanna S, Jackson AU, Scuteri A, Bonnycastle LL, Clarke R., et al. Newly identifi ed loci that infl uence lipid concentrations and risk of coronary artery disease. Nat Genet. 2008;40:161-9.
-
(2008)
Nat. Genet.
, vol.40
, pp. 161-169
-
-
Willer, C.J.1
Sanna, S.2
Jackson, A.U.3
Scuteri, A.4
Bonnycastle, L.L.5
Clarke, R.6
-
36
-
-
70749096913
-
Myocardial Infarction Genetics Consortium. Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants
-
M yocardial Infarction Genetics Consortium. Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet. 2009;4:334-41.
-
(2009)
Nat. Genet.
, vol.4
, pp. 334-341
-
-
-
37
-
-
61349137526
-
Genome-wide haplotype association study identifi es the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease
-
Wellcome Trust Case Control Consortium Cardiogenics Consortium
-
Trégouët DA, Kónig IR, Erdmann J, Munteanu A, Braund PS, Hall AS., et al., Wellcome Trust Case Control Consortium; Cardiogenics Consortium. Genome-wide haplotype association study identifi es the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease. Nat Genet. 2009;41:283-5.
-
(2009)
Nat. Genet.
, vol.41
, pp. 283-285
-
-
Trégouët, D.A.1
Kónig, I.R.2
Erdmann, J.3
Munteanu, A.4
Braund, P.S.5
Hall, A.S.6
-
38
-
-
61349089164
-
Sequence variants aff ecting eosinophil numbers associate with asthma and myocardial infarction
-
Gudbjartsson DF, Bjornsdottir US, 38. Halapi E, Helgadottir A, Sulem P, Jonsdottir GM., et al. Sequence variants aff ecting eosinophil numbers associate with asthma and myocardial infarction. Nat Genet. 2009;41:342-7.
-
(2009)
Nat. Genet.
, Issue.41
, pp. 342-347
-
-
Gudbjartsson, D.F.1
Bjornsdottir, U.S.2
Halapi, E.3
Helgadottir, A.4
Sulem, P.5
Jonsdottir, G.M.6
-
39
-
-
70350139601
-
Megakaryoblastic leukemia factor-1 gene in the susceptibility to coronary artery disease
-
H inohara K, Nakajima T, Yasunami M, Houda S, Sasaoka T, Yamamoto K., et al. Megakaryoblastic leukemia factor-1 gene in the susceptibility to coronary artery disease. Hum Genet. 2009;126:539-47.
-
(2009)
Hum. Genet.
, vol.126
, pp. 539-547
-
-
Hinohara, K.1
Nakajima, T.2
Yasunami, M.3
Houda, S.4
Sasaoka, T.5
Yamamoto, K.6
-
40
-
-
78049314943
-
A multilocus genetic risk score for coronary heart disease: Case-control and prospective cohort analyses
-
R ipatti S, Tikkanen E, Orho-Melander M. A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses. Lancet 2010;376:1393-400.
-
Lancet
, vol.2010
, Issue.376
, pp. 1393-1400
-
-
Ripatti, S.1
Tikkanen, E.2
Orho-Melander, M.3
-
41
-
-
78049234740
-
Genomic risk prediction
-
S andhu M, Wood A, Young E. Genomic risk prediction. Lancet 2010;376:1366-7.
-
Lancet
, vol.2010
, Issue.376
, pp. 1366-1367
-
-
Sandhu, M.1
Wood, A.2
Young, E.3
-
42
-
-
80052471862
-
Myocardial Infarction Genetics Consortium Wellcome Trust Case Control Consortium Identifi cation of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: Two genome-wide association studies
-
R eilly MP, Li M, He J, Ferguson JF, Stylianou IM, Mehta NN., et al. Myocardial Infarction Genetics Consortium; Wellcome Trust Case Control Consortium.. Identifi cation of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: Two genome-wide association studies. Lancet 2011;10:61996-4.
-
Lancet
, vol.2011
, Issue.10
, pp. 61996-61994
-
-
Reilly, M.P.1
Li, M.2
He, J.3
Ferguson, J.F.4
Stylianou, I.M.5
Mehta, N.N.6
-
43
-
-
79251619565
-
Addressing the complexity of cardiovascular disease by design
-
L otta LA, Peyvandi F. Addressing the complexity of cardiovascular disease by design. Lancet 2011;377:356-8.
-
Lancet
, vol.2011
, Issue.377
, pp. 356-358
-
-
Lotta, L.A.1
Peyvandi, F.2
-
44
-
-
79952069515
-
Meta-analysis of genome-wide association studies in 80000 subjects identifi es multiple loci for C-reactive protein
-
Dehghan A, Dupuis J, Barbalic M, Bis JC, Eiriksdottir G, Lu C., et al. Meta-analysis of genome-wide association studies in 80,000 subjects identifi es multiple loci for C-reactive protein. Circulation 2011;123:731-8.
-
Circulation
, vol.2011
, Issue.123
, pp. 731-738
-
-
Dehghan, A.1
Dupuis, J.2
Barbalic, M.3
Bis, J.C.4
Eiriksdottir, G.5
Lu, C.6
-
45
-
-
61349177857
-
Italian Atherosclerosis Thrombosis and Vascular biology working group myocardial infarction genetics consortium
-
Wellcome Trust Case Control Consortium; Cardiogenics Consortium New susceptibility locus for coronary artery disease on chromosome 3q22.3.
-
Erdmann J, Grosshennig A, Braund PS, Kónig IR, Hengstenberg C, Hall AS.,et al., Italian Atherosclerosis, Th rombosis, and Vascular Biology Working Group; Myocardial Infarction Genetics Consortium; Wellcome Trust Case Control Consortium; Cardiogenics Consortium. New susceptibility locus for coronary artery disease on chromosome 3q22.3. Nat Genet. 2009;41:280-2.
-
(2009)
Nat. Genet.
, vol.41
, pp. 280-282
-
-
Erdmann, J.1
Grosshennig, A.2
Braund, P.S.3
Kónig, I.R.4
Hengstenberg, C.5
Hall, A.S.6
-
46
-
-
79951473520
-
9P21 DNA variants associated with coronary artery impair interferon-Y signaling response
-
H arismendy O, Notani D, Song X, Rahim NG, Tanasa B, Heintzman N., et al. 9P21 DNA variants associated with coronary artery impair interferon-Y signaling response. Nature Rev Genet. 2011;3:264-8.
-
Nature Rev. Genet.
, vol.2011
, Issue.3
, pp. 264-268
-
-
Harismendy, O.1
Notani, D.2
Song, X.3
Rahim, N.G.4
Tanasa, B.5
Heintzman, N.6
|