Megakaryoblastic leukemia factor-1 gene in the susceptibility to coronary artery disease

Human Genetics

Volumn 126, Issue 4, 2009, Pages 539-547

  Hinohara, Kunihiko ^a   Nakajima, Toshiaki ^a   Yasunami, Michio ^a   Houda, Shigeru ^b   Sasaoka, Taishi ^b   Yamamoto, Ken ^c   Lee, Bok Soo ^d   Shibata, Hiroki ^a   Tanaka Takahashi, Yumiko ^a   Takahashi, Megumi ^a   Arimura, Takuro ^a   Sato, Akinori ^a   Naruse, Taeko ^a   Ban, Jimin ^d   Inoko, Hidetoshi ^e   Yamada, Yoshiji ^f   Sawabe, Motoji ^g   Park, Jeong Euy ^d   Izumi, Toru ^b   Kimura, Akinori ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

^d Sungkyunkwan University School of Medicine   (South Korea)

^e TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^f MIE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^g Tokyo Metropolitan Institute of Gerontology   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MEGAKARYOBLASTIC LEUKEMIA FACTOR 1; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; FEMALE; GENE EXPRESSION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; HUMAN; MALE; MICROSATELLITE MARKER; PATHOGENESIS; PRIORITY JOURNAL; PROMOTER REGION; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; B-LYMPHOCYTES; CASE-CONTROL STUDIES; CELLS, CULTURED; CORONARY ARTERY DISEASE; DISEASE SUSCEPTIBILITY; DNA PRIMERS; DNA-BINDING PROTEINS; FEMALE; GENETIC TESTING; GENOTYPE; HUMANS; JAPAN; KOREA; MALE; MIDDLE AGED; ONCOGENE PROTEINS, FUSION; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RISK FACTORS; RNA, MESSENGER;

ANGINA;

EID: 70350139601     PISSN: 03406717     EISSN: 14321203     Source Type: Journal    
DOI: 10.1007/s00439-009-0698-6     Document Type: Article

References (37)

1. Abifadel M, Varret M, Rabès JP, Allard D, Ouguerram K et al (2003) Mutations in PCSK9 cause autosomal dominant hypercholesterolemia. Nat Genet 34:154-156
2. Barrett JC, Fry B, Maller J, Daly MJ (2005) Haploview: Analysis and visualization of LD and haplotype maps. Bioinformatics 21:263-265
3. Cardon LR, Bell JI (2001) Association study designs for complex diseases. Nat Rev Genet 2:91-99
4. Cen B, Selvaraj A, Prywes R (2004) Myocardin/MKL family of SRF coactivators: Key regulators of immediate early and muscle specific gene expression. J Cell Biochem 93:74-82
5. Chen SN, Ballantyne CM, Gotto AM Jr, Tan Y, Willerson JT et al (2005) A common PCSK9 haplotype, encompassing the E670G coding single nucleotide polymorphism, is a novel genetic marker for plasma low-density lipoprotein cholesterol levels and severity of coronary atherosclerosis. J Am Coll Cardiol 45:1611-1619
6. Ciruzzi M, Schargrodsky H, Rozlosnik J, Pramparo P, Delmonte H et al (1997) Frequency of family history of acute myocardial infarction in patients with acute myocardial infarction. Am J Cardiol 80:122-127
7. Collins HE, Li H, Inda SE, Anderson J, Laiho K et al (2000) A simple and accurate method for determination of microsatellite total allele content differences between DNA pools. Hum Genet 106:218-226
8. Coronary Artery Disease Consortium (2009) Large scale association analysis of novel genetic loci for coronary artery disease. Arterioscler Thromb Vasc Biol 29:774-780
9. Du KL, Chen M, Li J, Lepore JJ, Mericko P et al (2004) Megakaryoblastic leukemia factor-1 transduces cytoskeletal signals and induces smooth muscle cell differentiation from undifferentiated embryonic stem cells. J Biol Chem 279:17578-17586
10. Ebana Y, Ozaki K, Inoue K, Sato H, Iida A et al (2007) A functional SNP in ITIH3 is associated with susceptibility to myocardial infarction. J Hum Genet 52:220-229
11. Elberg G, Chen L, Elberg D, Chan MD, Logan CJ et al (2008) MKL1 mediates TGF-beta1-induced alpha-smooth muscle actin expression in human renal epithelial cells. Am J Physiol Renal Physiol 294:F1116-F1128
12. Erdmann J, Grosshennig A, Braund PS, König IR, Hengstenberg C et al (2009) New susceptibility locus for coronary artery disease on chromosome 3q22.3. Nat Genet 41:280-282
13. Evans D, Beil FU (2006) The E670G SNP in the PCSK9 gene is associated with polygenic hypercholesterolemia in men but not in women. BMC Med Genet 7:66
14. Helgadottir A, Thorleifsson G, Manolescu A, Gretarsdottir S, Blondal T et al (2007) A common variant on chromosome 9p21 affects the risk of myocardial infarction. Science 316:1491-1493
15. Hinohara K, Nakajima T, Takahashi M, Hohda S, Sasaoka T et al (2008) Replication of the association between a chromosome 9p21 polymorphism and coronary artery disease in Japanese and Korean populations. J Hum Genet 53:357-359
16. Hirschhorn JN, Daly MJ (2005) Genome-wide association studies for common diseases and complex traits. Nat Rev Genet 6:95-108
17. Hohda S, Kimura A, Sasaoka T, Hayashi T, Ueda K et al (2003) Association study of CD14 polymorphism with myocardial infarction in a Japanese population. Jpn Heart J 44:613-622
18. Kawashima M, Tamiya G, Oka A, Hohjoh H, Juji T et al (2006) Genomewide association analysis of human narcolepsy and a new resistance gene. Am J Hum Genet 79:252-263
19. Lopez AD, Mathers CD, Ezzati M, Jamiso DT, Murray CJ (2006) Global and regional burden of disease and risk factors, 2001: Systematic analysis of population health data. Lancet 367:1747-1757
20. Mantel N, Haenszel W (1959) Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 22:719-748
21. McPherson R, Pertsemlidis A, Kavaslar N, Stewart A, Roberts R et al (2007) A common allele on chromosome 9 associated with coronary heart disease. Science 316:1488-1491
22. Morgan TM, Krumholz HM, Lifton RP, Spertus JA (2007) Nonvalidation of reported genetic risk factors for acute coronary syndrome in a large-scale replication study. JAMA 297:1551-1561
23. Myocardial Infarction Genetics Consortium (2009) Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet 41:334-341
24. Ohashi J, Tokunaga K (2003) Power of genomewide linkage disequilibrium testing by using microsatellite markers. J Hum Genet 48:487-491
25. Ozaki K, Ohnishi Y, Iida A, Sekine A, Yamada R et al (2002) Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction. Nat Genet 32:650-654
26. Ozaki K, Sato H, Inoue K, Tsunoda T, Sakata Y et al (2009) SNPs in BRAP associated with risk of myocardial infarction in Asian populations. Nat Genet 41:329-333
27. Parmacek MS (2007) Myocardin-related transcription factors: Critical coactivators regulating cardiovascular development and adaptation. Circ Res 100:633-644
28. Ross R (1999) Atherosclerosis - an inflammatory disease. N Engl J Med 340:115-126
29. Samani NJ, Erdmann J, Hall AS, Hengstenberg C, Mangino M et al (2007) Genomewide association analysis of coronary artery disease. N Engl J Med 357:443-453
30. Sata M, Saiura A, Kunisato A, Tojo A, Okada S et al (2002) Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis. Nat Med 8:403-409
31. Shibata H, Yasunami M, Obuchi N, Takahashi M, Kobayashi Y et al (2006) Direct determination of single nucleotide polymorphism haplotype of NFKBIL1 promoter polymorphism by DNA conformation analysis and its application to association study of chronic inflammatory diseases. Hum Immunol 67:363-373
32. Shiffman D, Ellis SG, Rowland CM, Malloy MJ, Luke MM et al (2005) Identification of four gene variants associated with myocardial infarction. Am J Hum Genet 77:596-605
33. Tamiya G, Shinya M, Imanishi T, Ikuta T, Makino S et al (2005) Whole genome association study of rheumatoid arthritis using 27 039 microsatellites. Hum Mol Genet 14:2305-2321
34. Trégoüt DA, König IR, Erdmann J, Munteanu A, Braund PS, Hall AS et al (2009) Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease. Nat Genet 41:283-285
35. Wang Q (2005) Molecular genetics of coronary artery disease. Curr Opin Cardiol 20:182-188
36. Wellcome Trust Case Control Consortium (2007) Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447:661-678
37. Willer CJ, Sanna S, Jackson AU, Scuteri A, Bonnycastle LL et al (2008) Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat Genet 40:161-169