메뉴 건너뛰기




Volumn 152, Issue 9, 2011, Pages 3306-3311

Minireview: Cracking the metabolic code for thyroid hormone signaling

Author keywords

[No Author keywords available]

Indexed keywords

LIOTHYRONINE; LIPID; OXIDOREDUCTASE; THYROID HORMONE; THYROXINE; TYPE 2 DEIODINASE; TYPE 3 DEIODINASE; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 1;

EID: 80052457588     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2011-1104     Document Type: Short Survey
Times cited : (77)

References (63)
  • 1
    • 67649842310 scopus 로고    scopus 로고
    • Minireview: Pathophysiological importance of thyroid hormone transporters
    • Heuer H, Visser TJ 2009 Minireview: pathophysiological importance of thyroid hormone transporters. Endocrinology 150:1078-1083
    • (2009) Endocrinology , vol.150 , pp. 1078-1083
    • Heuer, H.1    Visser, T.J.2
  • 2
    • 77953639982 scopus 로고    scopus 로고
    • Molecular aspects of thyroid hormone actions
    • Cheng SY, Leonard JL, Davis PJ 2010 Molecular aspects of thyroid hormone actions. Endocr Rev 31:139-170
    • (2010) Endocr Rev , vol.31 , pp. 139-170
    • Cheng, S.Y.1    Leonard, J.L.2    Davis, P.J.3
  • 3
    • 25144518194 scopus 로고    scopus 로고
    • Cellular and structural biology of the deiodinases
    • DOI 10.1089/thy.2005.15.777
    • Bianco AC, Larsen PR 2005 Cellular and structural biology of the deiodinases. Thyroid 15:777-786 (Pubitemid 41339258)
    • (2005) Thyroid , vol.15 , Issue.8 , pp. 777-786
    • Bianco, A.C.1    Larsen, P.R.2
  • 5
    • 0033680077 scopus 로고    scopus 로고
    • Distinct subcellular localization of transiently expressed types 1 and 2 iodothyronine deiodinases as determined by immunofluorescence confocal microscopy
    • Baqui MM, Gereben B, Harney JW, Larsen PR, Bianco AC 2000 Distinct subcellular localization of transiently expressed types 1 and 2 iodothyronine deiodinases as determined by immunofluorescence confocal microscopy. Endocrinology 141:4309-4312
    • (2000) Endocrinology , vol.141 , pp. 4309-4312
    • Baqui, M.M.1    Gereben, B.2    Harney, J.W.3    Larsen, P.R.4    Bianco, A.C.5
  • 8
    • 0025979337 scopus 로고
    • Type I iodothyronine deiodinase is a selenocysteine-containing enzyme
    • Berry MJ, Banu L, Larsen PR 1991 Type I iodothyronine deiodinase is a selenocysteine-containing enzyme. Nature 349:438-440 (Pubitemid 21926109)
    • (1991) Nature , vol.349 , Issue.6308 , pp. 438-440
    • Berry, M.J.1    Banu, L.2    Larsen, P.R.3
  • 12
    • 39749177046 scopus 로고    scopus 로고
    • Activation and inactivation of thyroid hormone by deiodinases: Local action with general consequences
    • Gereben B, Zeöld A, Dentice M, Salvatore D, Bianco AC 2008 Activation and inactivation of thyroid hormone by deiodinases: local action with general consequences. Cell Mol Life Sci 65:570-590
    • (2008) Cell Mol Life Sci , vol.65 , pp. 570-590
    • Gereben, B.1    Zeöld, A.2    Dentice, M.3    Salvatore, D.4    Bianco, A.C.5
  • 13
    • 85047681858 scopus 로고    scopus 로고
    • Characterization of the 5′-flanking and 5′-untranslated regions of the cyclic adenosine 3′,5′-monophosphate-responsive human type 2 iodothyronine deiodinase gene
    • Bartha T, Kim SW, Salvatore D, Gereben B, Tu HM, Harney JW, Rudas P, Larsen PR 2000 Characterization of the 5′-flanking and 5′-untranslated regions of the cyclic adenosine 3′,5′- monophosphate-responsive human type 2 iodothyronine deiodinase gene. Endocrinology 141:229-237
    • (2000) Endocrinology , vol.141 , pp. 229-237
    • Bartha, T.1    Kim, S.W.2    Salvatore, D.3    Gereben, B.4    Tu, H.M.5    Harney, J.W.6    Rudas, P.7    Larsen, P.R.8
  • 16
    • 0033279284 scopus 로고    scopus 로고
    • Regulation of type 3 iodothyronine deiodinase expression in cultured rat astrocytes: Role of the Erk cascade
    • DOI 10.1210/en.140.6.2917
    • Pallud S, Ramaugé M, Gavaret JM, Lennon AM, Munsch N, St Germain DL, Pierre M, Courtin F 1999 Regulation of type 3 iodothyronine deiodinase expression in cultured rat astrocytes: Role of the Erk cascade. Endocrinology 140:2917-2923 (Pubitemid 32245174)
    • (1999) Endocrinology , vol.140 , Issue.6 , pp. 2917-2923
    • Pallud, S.1    Ramauge, M.2    Gavaret, J.-M.3    Lennon, A.-M.4    Munsch, N.5    St., G.D.L.6    Pierre, M.7    Courtin, F.8
  • 17
    • 28144445400 scopus 로고    scopus 로고
    • Transforming growth factor- B promotes inactivation of extracellular thyroid hormones via transcriptional stimulation of type 3 iodothyronine deiodinase
    • DOI 10.1210/me.2005-0173
    • Huang SA, Mulcahey MA, Crescenzi A, Chung M, Kim BW, Barnes C, Kuijt W, Turano H, Harney J, Larsen PR 2005 TGF-B promotes inactivation of extracellular thyroid hormones via transcriptional stimulation of type 3 iodothyronine deiodinase. Mol Endocrinol 19:3126-3136 (Pubitemid 41697726)
    • (2005) Molecular Endocrinology , vol.19 , Issue.12 , pp. 3126-3136
    • Huang, S.A.1    Mulcahey, M.A.2    Crescenzi, A.3    Chung, M.4    Kim, B.W.5    Barnes, C.6    Kuijt, W.7    Turano, H.8    Harney, J.9    Larsen, P.R.10
  • 22
    • 0033650596 scopus 로고    scopus 로고
    • Selective proteolysis of human type 2 deiodinase: A novel ubiquitin-proteasomal mediated mechanism for regulation of hormone activation
    • Gereben B, Goncalves C, Harney JW, Larsen PR, Bianco AC 2000 Selective proteolysis of human type 2 deiodinase: a novel ubiquitin-proteasomal mediated mechanism for regulation of hormone activation. Mol Endocrinol 14:1697-1708
    • (2000) Mol Endocrinol , vol.14 , pp. 1697-1708
    • Gereben, B.1    Goncalves, C.2    Harney, J.W.3    Larsen, P.R.4    Bianco, A.C.5
  • 23
    • 0036715341 scopus 로고    scopus 로고
    • Ubc6p and Ubc7p are required for normal and substrate-induced endoplasmic reticulum-associated degradation of the human selenoprotein type 2 iodothyronine monodeiodinase
    • DOI 10.1210/me.2002-0135
    • Botero D, Gereben B, Goncalves C, De Jesus LA, Harney JW, Bianco AC 2002 Ubc6p and Ubc7p are required for normal and substrate-induced endoplasmic reticulum-associated degradation of the human selenoprotein type 2 iodothyronine monodeiodinase. Mol Endocrinol 16:1999-2007 (Pubitemid 35013450)
    • (2002) Molecular Endocrinology , vol.16 , Issue.9 , pp. 1999-2007
    • Botero, D.1    Gereben, B.2    Goncalves, C.3    De Jesus, L.A.4    Harney, J.W.5    Bianco, A.C.6
  • 24
    • 0347480259 scopus 로고    scopus 로고
    • Endoplasmic Reticulum-Associated Degradation of the Human Type 2 Iodothyronine Deiodinase (D2) is Mediated via an Association between Mammalian UBC7 and the Carboxyl Region of D2
    • DOI 10.1210/me.2003-0082
    • Kim BW, Zavacki AM, Curcio-Morelli C, Dentice M, Harney JW, Larsen PR, Bianco AC 2003 Endoplasmic reticulum-associated degradation of the human type 2 iodothyronine deiodinase (D2) is mediated via an association between mammalian UBC7 and the carboxyl region of D2. Mol Endocrinol 17:2603-2612 (Pubitemid 37542221)
    • (2003) Molecular Endocrinology , vol.17 , Issue.12 , pp. 2603-2612
    • Kim, B.W.1    Zavacki, A.M.2    Curcio-Morelli, C.3    Dentice, M.4    Harney, J.W.5    Larsen, P.R.6    Bianco, A.C.7
  • 27
    • 0345714814 scopus 로고    scopus 로고
    • Biologic Variation is Important for Interpretation of Thyroid Function Tests
    • Andersen S, Bruun NH, Pedersen KM, Laurberg P 2003 Biologic variation is important for interpretation of thyroid function tests. Thyroid 13:1069-1078 (Pubitemid 37464559)
    • (2003) Thyroid , vol.13 , Issue.11 , pp. 1069-1078
    • Andersen, S.1    Bruun, N.H.2    Pedersen, K.M.3    Laurberg, P.4
  • 28
    • 27744449069 scopus 로고    scopus 로고
    • Adaptive activation of thyroid hormone and energy expenditure
    • DOI 10.1007/s10540-005-2885-6
    • Bianco AC, Maia AL, Da Silva WS, Christoffolete MA 2005 Adaptive activation of thyroid hormone and energy expenditure. Biosci Rep 25:191-208 (Pubitemid 41613787)
    • (2005) Bioscience Reports , vol.25 , Issue.3-4 , pp. 191-208
    • Bianco, A.C.1    Maia, A.L.2    Da, S.W.S.3    Christoffolete, M.A.4
  • 29
    • 0002626757 scopus 로고    scopus 로고
    • Catecholamines and the sympathoadrenal system in thyrotoxicosis
    • Braverman LE, Utiger RD, eds. Philadelphia: Lippincott, Willians & Wilkins
    • Silva JE 2000 Catecholamines and the sympathoadrenal system in thyrotoxicosis. In: Braverman LE, Utiger RD, eds. Werner and Ingbar's the thyroid: a fundamental and clinical text. Philadelphia: Lippincott, Willians & Wilkins; 642-651
    • (2000) Werner and Ingbar's the Thyroid: A Fundamental and Clinical Text , pp. 642-651
    • Silva, J.E.1
  • 30
    • 0002626757 scopus 로고    scopus 로고
    • Catecholamines and the sympathoadrenal system in hypothyroidism
    • Braverman LE, Utiger RD eds. Philadelphia: Lippincott, Willians & Wilkins
    • Silva JE 2000 Catecholamines and the sympathoadrenal system in hypothyroidism. In: Braverman LE, Utiger RD eds. Werner and Ingbar's the thyroid: a fundamental and clinical text. Philadelphia: Lippincott, Willians & Wilkins; 820-823
    • (2000) Werner and Ingbar's the Thyroid: A Fundamental and Clinical Text , pp. 820-823
    • Silva, J.E.1
  • 31
    • 79953225879 scopus 로고    scopus 로고
    • Disruption of thyroid hormone activation in type 2 deiodinase knockout mice causes obesity with glucose intolerance and liver steatosis only at thermoneutrality
    • Castillo M, Hall JA, Correa-Medina M, Ueta C, Won Kang H, Cohen DE, Bianco AC 2011 Disruption of thyroid hormone activation in type 2 deiodinase knockout mice causes obesity with glucose intolerance and liver steatosis only at thermoneutrality. Diabetes 60:1082-1089
    • (2011) Diabetes , vol.60 , pp. 1082-1089
    • Castillo, M.1    Hall, J.A.2    Correa-Medina, M.3    Ueta, C.4    Won Kang, H.5    Cohen, D.E.6    Bianco, A.C.7
  • 33
    • 0031733178 scopus 로고    scopus 로고
    • Thyroxine 5'-deiodination mediates norepinephrine induced lipogenesis in dispersed brown adipocytes
    • DOI 10.1210/en.139.2.571
    • Bianco AC, Carvalho SD, Carvalho CR, Rabelo R, Moriscot AS 1998 Thyroxine 5′-deiodination mediates norepinephrine-induced lipogenesis in dispersed brown adipocytes. Endocrinology 139:571-578 (Pubitemid 28513205)
    • (1998) Endocrinology , vol.139 , Issue.2 , pp. 571-578
    • Bianco, A.C.1    Carvalho, S.D.2    Carvalho, C.R.F.3    Rabelo, R.4    Moriscot, A.S.5
  • 34
    • 0023119510 scopus 로고
    • Intracellular conversion of thyroxine to triiodothyronine is required for the optimal thermogenic funciton of brown adipose tissue
    • Bianco AC, Silva JE 1987 Intracellular conversion of thyroxine to triiodothyronine is required for the optimal thermogenic function of brown adipose tissue. J Clin Invest 79:295-300 (Pubitemid 17232532)
    • (1987) Journal of Clinical Investigation , vol.79 , Issue.1 , pp. 295-300
    • Bianco, A.C.1    Silva, J.E.2
  • 36
    • 39749153526 scopus 로고    scopus 로고
    • Reawakened interest in type III iodothyronine deiodinase in critical illness and injury
    • DOI 10.1038/ncpendmet0727, PII NCPENDMET0727
    • Huang SA, Bianco AC 2008 Reawakened interest in type III iodothyronine deiodinase in critical illness and injury. Nat Clin Pract Endocrinol Metab 4:148-155 (Pubitemid 351301780)
    • (2008) Nature Clinical Practice Endocrinology and Metabolism , vol.4 , Issue.3 , pp. 148-155
    • Huang, S.A.1    Bianco, A.C.2
  • 40
    • 79551501758 scopus 로고    scopus 로고
    • The chemical chaperones tauroursodeoxycholic and 4-phenylbutyric acid accelerate thyroid hormone activation and energy expenditure
    • Da-Silva WS, Ribich S, Arrojo e Drigo R, Castillo M, Patti ME, Bianco AC 2011 The chemical chaperones tauroursodeoxycholic and 4-phenylbutyric acid accelerate thyroid hormone activation and energy expenditure. FEBS Lett 585:539-544
    • (2011) FEBS Lett , vol.585 , pp. 539-544
    • Da-Silva, W.S.1    Ribich, S.2    Arrojo E Drigo, R.3    Castillo, M.4    Patti, M.E.5    Bianco, A.C.6
  • 46
    • 25144515952 scopus 로고    scopus 로고
    • Role of thyroid hormone deiodination in the hypothalamus
    • DOI 10.1089/thy.2005.15.883
    • Lechan RM, Fekete C 2005 Role of thyroid hormone deiodination in the hypothalamus. Thyroid 15:883-897 (Pubitemid 41339267)
    • (2005) Thyroid , vol.15 , Issue.8 , pp. 883-897
    • Lechan, R.M.1    Fekete, C.2
  • 47
    • 39549085551 scopus 로고    scopus 로고
    • The role of the thyrotropin-releasing hormone (TRH) neuron as a metabolic sensor
    • DOI 10.1089/thy.2007.0251
    • Hollenberg AN 2008 The role of the thyrotropin-releasing hormone (TRH) neuron as a metabolic sensor. Thyroid 18:131-139 (Pubitemid 351278374)
    • (2008) Thyroid , vol.18 , Issue.2 , pp. 131-139
    • Hollenberg, A.N.1
  • 48
    • 24044549667 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide (LPS)-induced type 2 iodothyronine deiodinase (D2) activation in the mediobasal hypothalamus (MBH) is independent of the LPS-induced fall in serum thyroid hormone levels
    • DOI 10.1016/j.brainres.2005.07.021, PII S0006899305010681
    • Fekete C, Sarkar S, Christoffolete MA, Emerson CH, Bianco AC, Lechan RM 2005 Bacterial lipopolysaccharide (LPS)-induced type 2 iodothyronine deiodinase (D2) activation in the mediobasal hypothalamus (MBH) is independent of the LPS-induced fall in serum thyroid hormone levels. Brain Res 1056:97-99 (Pubitemid 41219362)
    • (2005) Brain Research , vol.1056 , Issue.1 , pp. 97-99
    • Fekete, C.1    Sarkar, S.2    Christoffolete, M.A.3    Emerson, C.H.4    Bianco, A.C.5    Lechan, R.M.6
  • 49
    • 0030786397 scopus 로고    scopus 로고
    • Regional distribution of type 2 thyroxine deiodinase messenger ribonucleic acid in rat hypothalamus and pituitary and its regulation by thyroid hormone
    • DOI 10.1210/en.138.8.3359
    • Tu HM, Kim SW, Salvatore D, Bartha T, Legradi G, Larsen PR, Lechan RM 1997 Regional distribution of type 2 thyroxine deiodinase messenger ribonucleic acid in rat hypothalamus and Pituitary and its regulation by thyroid hormone. Endocrinology 138:3359-3368 (Pubitemid 27345689)
    • (1997) Endocrinology , vol.138 , Issue.8 , pp. 3359-3368
    • Tu, H.M.1    Kim, S.-W.2    Salvatore, D.3    Bartha, T.4    Legradi, G.5    Larsen, P.R.6    Lechan, R.M.7
  • 51
    • 0031023968 scopus 로고    scopus 로고
    • Evidence for circadian variations of thyroid hormone concentrations and type II 5'-iodothyronine deiodinase activity in the rat central nervous system
    • Campos-Barros A, Musa A, Flechner A, Hessenius C, Gaio U, Meinhold H, Baumgartner A 1997 Evidence for circadian variations of thyroid hormone concentrations and type II 5′-iodothyronine deiodinase activity in the rat central nervous system. J Neurochem 68:795-803 (Pubitemid 27044745)
    • (1997) Journal of Neurochemistry , vol.68 , Issue.2 , pp. 795-803
    • Campos-Barros, A.1    Musa, A.2    Flechner, A.3    Hessenius, C.4    Gaio, U.5    Meinhold, H.6    Baumgartner, A.7
  • 52
    • 0031731577 scopus 로고    scopus 로고
    • Fasting-induced increase in type II iodothyronine deiodinase activity and messenger ribonucleic acid levels is not reversed by thyroxine in the rat hypothalamus
    • DOI 10.1210/en.139.6.2879
    • Diano S, Naftolin F, Goglia F, Horvath TL 1998 Fasting-induced increase in type II iodothyronine deiodinase activity and messenger ribonucleic acid levels is not reversed by thyroxine in the rat hypothalamus. Endocrinology 139:2879-2884 (Pubitemid 28512399)
    • (1998) Endocrinology , vol.139 , Issue.6 , pp. 2879-2884
    • Diano, S.1    Naftolin, F.2    Goglia, F.3    Horvath, T.L.4
  • 53
    • 0036893007 scopus 로고    scopus 로고
    • Neuropeptide Y1 and Y5 receptors mediate the effects of neuropeptide Y on the hypothalamic-pituitary-thyroid axis
    • DOI 10.1210/en.2002-220574
    • Fekete C, Sarkar S, Rand WM, Harney JW, Emerson CH, Bianco AC, Beck-Sickinger A, Lechan RM 2002 Neuropeptide Y1 and Y5 receptors mediate the effects of neuropeptide Y on the hypothalamic-pituitary-thyroid axis. Endocrinology 143:4513-4519 (Pubitemid 35397590)
    • (2002) Endocrinology , vol.143 , Issue.12 , pp. 4513-4519
    • Fekete, C.1    Sarkar, S.2    Rand, W.M.3    Harney, J.W.4    Emerson, C.H.5    Bianco, A.C.6    Beck-Sickinger, A.7    Lechan, R.M.8
  • 55
    • 79958228940 scopus 로고    scopus 로고
    • Local control of thyroid hormone action - Role of type 2 deiodinase
    • Williams GR, Bassett JH 2011 Local control of thyroid hormone action - Role of type 2 deiodinase. J Endocrinol 209:261-272
    • (2011) J Endocrinol , vol.209 , pp. 261-272
    • Williams, G.R.1    Bassett, J.H.2
  • 56
    • 4644231760 scopus 로고    scopus 로고
    • The thyroid and the skeleton
    • DOI 10.1111/j.1365-2265.2004.02053.x
    • Murphy E, Williams GR 2004 The thyroid and the skeleton. Clin Endocrinol 61:285-298 (Pubitemid 39287057)
    • (2004) Clinical Endocrinology , vol.61 , Issue.3 , pp. 285-298
    • Murphy, E.1    Williams, G.R.2
  • 57
    • 53349165950 scopus 로고    scopus 로고
    • Deiodinase-mediated thyroid hormone inactivation minimizes thyroid hormone signaling in the early development of fetal skeleton
    • Capelo LP, Beber EH, Huang SA, Zorn TM, Bianco AC, Gouveia CH 2008 Deiodinase-mediated thyroid hormone inactivation minimizes thyroid hormone signaling in the early development of fetal skeleton. Bone 43:921-930
    • (2008) Bone , vol.43 , pp. 921-930
    • Capelo, L.P.1    Beber, E.H.2    Huang, S.A.3    Zorn, T.M.4    Bianco, A.C.5    Gouveia, C.H.6
  • 58
    • 11144221211 scopus 로고    scopus 로고
    • Type 2 iodothyronine selenodeiodinase is expressed throughout the mouse skeleton and in the MC3T3-E1 mouse osteoblastic cell line during differentiation
    • DOI 10.1210/en.2004-1043
    • Gouveia CH, Christoffolete MA, Zaitune CR, Dora JM, Harney JW, Maia AL, Bianco AC 2005 Type 2 iodothyronine selenodeiodinase is expressed throughout the mouse skeleton and in the MC3T3-E1 mouse osteoblastic cell line during differentiation. Endocrinology 146:195-200 (Pubitemid 40051739)
    • (2005) Endocrinology , vol.146 , Issue.1 , pp. 195-200
    • Gouveia, C.H.A.1    Christoffolete, M.A.2    Zaitune, C.R.3    Dora, J.M.4    Harney, J.W.5    Maia, A.L.6    Bianco, A.C.7
  • 61
    • 25144484840 scopus 로고    scopus 로고
    • Insights into the role of deiodinases from studies of genetically modified animals
    • DOI 10.1089/thy.2005.15.905
    • St Germain DL, Hernandez A, Schneider MJ, Galton VA 2005 Insights into the role of deiodinases from studies of genetically modified animals. Thyroid 15:905-916 (Pubitemid 41339269)
    • (2005) Thyroid , vol.15 , Issue.8 , pp. 905-916
    • St., G.D.L.1    Hernandez, A.2    Schneider, M.J.3    Galton, V.A.4
  • 63
    • 33845270781 scopus 로고    scopus 로고
    • Genetic variation in thyroid hormone pathway genes; polymorphisms in the TSH receptor and the iodothyronine deiodinases
    • DOI 10.1530/eje.1.02279
    • Peeters RP, Van der Deure WM, Visser TJ 2006 Genetic variation in thyroid hormone pathway genes; polymorphisms in the TSH receptor and the iodothyronine deiodinases. Eur J Endocrinol 155:655-662 (Pubitemid 44857488)
    • (2006) European Journal of Endocrinology , vol.155 , Issue.5 , pp. 655-662
    • Peeters, R.P.1    Van Der Deure, W.M.2    Visser, T.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.