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Volumn 31, Issue 3, 2011, Pages 155-164

The protein Z/protein Z-dependent protease inhibitor complex: Systemic or local control of coagulation?

Author keywords

Cancer; Protein Z; Protein Z dependent protease inhibitor; Thrombosis

Indexed keywords

BLOOD CLOTTING FACTOR 10A; FATTY ACID BINDING PROTEIN; FIBRIN; PROTEIN Z DEPENDENT PROTEASE INHIBITOR; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 80052439448     PISSN: 07209355     EISSN: None     Source Type: Journal    
DOI: 10.5482/ha-1161     Document Type: Review
Times cited : (25)

References (97)
  • 1
    • 0025145857 scopus 로고
    • Primary structure of vitamin K-dependent human protein Z
    • Sejima H, Hayashi T, Deyashiki Y et al. Primary structure of vitamin K-dependent human protein Z. Biochem Biophys Res Commun 1990; 171: 661-668.
    • (1990) Biochem Biophys Res Commun , vol.171 , pp. 661-668
    • Sejima, H.1    Hayashi, T.2    Deyashiki, Y.3
  • 2
    • 0032483018 scopus 로고    scopus 로고
    • Isolation of a protein Z-dependent plasma protease inhibitor
    • Han X, Fiehler R, Broze GJ Jr. Isolation of a protein Z-dependent plasma protease inhibitor. Proc Natl Acad Sci USA 1998; 95: 9250-9255.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9250-9255
    • Han, X.1    Fiehler, R.2    Broze Jr., G.J.3
  • 3
    • 0035067712 scopus 로고    scopus 로고
    • Protein Z circulates in plasma in a complex with protein Z-dependent protease inhibitor
    • Tabatabai A, Fiehler R, Broze GJ Jr. Protein Z circulates in plasma in a complex with protein Z-dependent protease inhibitor. Thromb Haemost 2001; 85: 655-660.
    • (2001) Thromb Haemost , vol.85 , pp. 655-660
    • Tabatabai, A.1    Fiehler, R.2    Broze Jr., G.J.3
  • 4
    • 0034612374 scopus 로고    scopus 로고
    • Prothrombotic phenotype of protein Z deficiency
    • Yin Z-F, Huang ZF, Cui J et al. Prothrombotic phenotype of protein Z deficiency. Proc Natl Acad Sci USA 2000; 97: 6734-6738.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 6734-6738
    • Yin, Z.-F.1    Huang, Z.F.2    Cui, J.3
  • 5
    • 46749095636 scopus 로고    scopus 로고
    • Protein Z-dependent protease inhibitor deficiency produces a more severe murine phenotype than protein Z deficiency
    • Zhang J, Tu Y, Lu L et al. Protein Z-dependent protease inhibitor deficiency produces a more severe murine phenotype than protein Z deficiency. Blood 2008; 111: 4973-4978.
    • (2008) Blood , vol.111 , pp. 4973-4978
    • Zhang, J.1    Tu, Y.2    Lu, L.3
  • 6
    • 0034329329 scopus 로고    scopus 로고
    • Characterization of the protein Z-dependent protease inhibitor
    • Han X, Fiehler R, Broze GJ Jr. Characterization of the protein Z-dependent protease inhibitor. Blood 2000; 96: 3049-3055.
    • (2000) Blood , vol.96 , pp. 3049-3055
    • Han, X.1    Fiehler, R.2    Broze Jr., G.J.3
  • 7
    • 54949142813 scopus 로고    scopus 로고
    • Protein Z, a protein seeking a pathology
    • Vasse M. Protein Z, a protein seeking a pathology. Thromb Haemost 2008; 100: 548-556.
    • (2008) Thromb Haemost , vol.100 , pp. 548-556
    • Vasse, M.1
  • 8
    • 33947532591 scopus 로고    scopus 로고
    • Protein Z/Z-dependent protease inhibitor (PZ/ZPI) anticoagulant system and thrombosis
    • Corral J, González-Conejero R, Hernández-Espinosa D et al. Protein Z/Z-dependent protease inhibitor (PZ/ZPI) anticoagulant system and thrombosis. Br J Haematol 2007; 137: 99-108.
    • (2007) Br J Haematol , vol.137 , pp. 99-108
    • Corral, J.1    González-Conejero, R.2    Hernández-Espinosa, D.3
  • 9
    • 77952068204 scopus 로고    scopus 로고
    • A meta-analysis of potential risks of low levels of protein Z for diseases related to vascular thrombosis
    • Sofi F, Cesari F, Abbate R et al. A meta-analysis of potential risks of low levels of protein Z for diseases related to vascular thrombosis. Thromb Haemost 2010; 103: 749-756.
    • (2010) Thromb Haemost , vol.103 , pp. 749-756
    • Sofi, F.1    Cesari, F.2    Abbate, R.3
  • 10
    • 0023277155 scopus 로고
    • Human plasma protein Z antigen: range in normal subjects and effect of warfarine therapy
    • Miletich JP, Broze GJ Jr. Human plasma protein Z antigen: range in normal subjects and effect of warfarine therapy. Blood 1987; 69: 1580-1586.
    • (1987) Blood , vol.69 , pp. 1580-1586
    • Miletich, J.P.1    Broze Jr., G.J.2
  • 11
    • 17044400649 scopus 로고    scopus 로고
    • A naturally occurring E30Q mutation in the Gla domain of protein Z causes its impaired secretion and subsequent deficiency
    • Souri M, Koseki-Kuno S, Iwata H et al. A naturally occurring E30Q mutation in the Gla domain of protein Z causes its impaired secretion and subsequent deficiency. Blood 2005; 105: 3149-3154.
    • (2005) Blood , vol.105 , pp. 3149-3154
    • Souri, M.1    Koseki-Kuno, S.2    Iwata, H.3
  • 12
    • 28444499682 scopus 로고    scopus 로고
    • An additional Glu30Lys substitution in the Gla domain of the protein Z gene is not a common polymorphism but a rare mutation, which would cause its deficiency
    • Iwata H, Souri M, Kemkes-Matthes B et al. An additional Glu30Lys substitution in the Gla domain of the protein Z gene is not a common polymorphism but a rare mutation, which would cause its deficiency. J Thromb Haemost 2005; 3: 2360-2361.
    • (2005) J Thromb Haemost , vol.3 , pp. 2360-2361
    • Iwata, H.1    Souri, M.2    Kemkes-Matthes, B.3
  • 13
    • 65549102264 scopus 로고    scopus 로고
    • Unique secretion mode of human protein Z: its Gla domain is responsible for inefficient, vitamin K-dependent and warfarin-sensitive secretion
    • Souri M, Iwata H, Zhang WG et al. Unique secretion mode of human protein Z: its Gla domain is responsible for inefficient, vitamin K-dependent and warfarin-sensitive secretion. Blood 2009; 113: 3857-3864.
    • (2009) Blood , vol.113 , pp. 3857-3864
    • Souri, M.1    Iwata, H.2    Zhang, W.G.3
  • 14
    • 41249102720 scopus 로고    scopus 로고
    • Determinants of vitamin K status in humans
    • Booth SL, Al Rajabi A. Determinants of vitamin K status in humans. Vitam Horm 2008; 78: 1-22.
    • (2008) Vitam Horm , vol.78 , pp. 1-22
    • Booth, S.L.1    Al Rajabi, A.2
  • 15
    • 77958520738 scopus 로고    scopus 로고
    • 17a-Ethinylestradiol rapidly alters transcript levels of murine coagulation genes via estrogen receptor a
    • Cleuren AC, Van der Linden IK, De Visser YP et al. 17a-Ethinylestradiol rapidly alters transcript levels of murine coagulation genes via estrogen receptor a. J Thromb Haemost 2010; 8: 1838-1846.
    • (2010) J Thromb Haemost , vol.8 , pp. 1838-1846
    • Cleuren, A.C.1    Van der Linden, I.K.2    De Visser, Y.P.3
  • 16
    • 15344345528 scopus 로고    scopus 로고
    • Protein Z and protein Z-dependent protease inhibitor. Determinants of levels and risk of venous thrombosis
    • Al-Shanqeeti A, van Hylckama Vlieg A, Berntorp E et al. Protein Z and protein Z-dependent protease inhibitor. Determinants of levels and risk of venous thrombosis. Thromb Haemost 2005; 93: 411-413.
    • (2005) Thromb Haemost , vol.93 , pp. 411-413
    • Al-Shanqeeti, A.1    van Hylckama Vlieg, A.2    Berntorp, E.3
  • 17
    • 13244289834 scopus 로고    scopus 로고
    • Protein Z gene polymorphisms are associated with protein Z plasma levels
    • Santacroce R, Cappucci F, Di Perna P et al. Protein Z gene polymorphisms are associated with protein Z plasma levels. J Thromb Haemost 2004; 2: 1197-1199.
    • (2004) J Thromb Haemost , vol.2 , pp. 1197-1199
    • Santacroce, R.1    Cappucci, F.2    Di Perna, P.3
  • 18
    • 0031671350 scopus 로고    scopus 로고
    • Protein Z in healthy human individuals and in patients with a bleeding tendency
    • Ravi S, Mauron T, Lämmle B et al. Protein Z in healthy human individuals and in patients with a bleeding tendency. Br J Haematol 1998; 102: 1219-1223.
    • (1998) Br J Haematol , vol.102 , pp. 1219-1223
    • Ravi, S.1    Mauron, T.2    Lämmle, B.3
  • 19
    • 33947322682 scopus 로고    scopus 로고
    • Association of low protein Z levels with ischemic stroke in young women
    • Heeb MJ, Fisher M, Paganini-Hill A. Association of low protein Z levels with ischemic stroke in young women. Thromb Haemost 2007; 97: 495-496.
    • (2007) Thromb Haemost , vol.97 , pp. 495-496
    • Heeb, M.J.1    Fisher, M.2    Paganini-Hill, A.3
  • 20
    • 2142773072 scopus 로고    scopus 로고
    • Autoimmune antiphospholipid antibodies impair the inhibition of activated factor X by protein Z/protein Z-dependent protease inhibitor
    • Forastiero RR, Martinuzzo ME, Lu L et al. Autoimmune antiphospholipid antibodies impair the inhibition of activated factor X by protein Z/protein Z-dependent protease inhibitor. J Thromb Haemost 2003; 1: 1764-1770.
    • (2003) J Thromb Haemost , vol.1 , pp. 1764-1770
    • Forastiero, R.R.1    Martinuzzo, M.E.2    Lu, L.3
  • 21
    • 0032510710 scopus 로고    scopus 로고
    • The gene for human protein Z is localized to chromosome 13 at band q34 and is coded by eight regular exons and one alternative exon
    • Fujimaki K, Yamazaki T, Taniwaki M et al. The gene for human protein Z is localized to chromosome 13 at band q34 and is coded by eight regular exons and one alternative exon. Biochemistry 1998; 37: 6838-6846.
    • (1998) Biochemistry , vol.37 , pp. 6838-6846
    • Fujimaki, K.1    Yamazaki, T.2    Taniwaki, M.3
  • 22
    • 0036166675 scopus 로고    scopus 로고
    • Weak regulation of protein Z biosynthesis by inflammatory cytokines
    • Vasse M, Denoyelle C, Legrand E et al. Weak regulation of protein Z biosynthesis by inflammatory cytokines. Thromb Haemost 2002; 87: 350-351.
    • (2002) Thromb Haemost , vol.87 , pp. 350-351
    • Vasse, M.1    Denoyelle, C.2    Legrand, E.3
  • 23
    • 4644245436 scopus 로고    scopus 로고
    • Heritability of plasma concentrations of clotting factors and measures of a prethrombotic state in a protein C-deficient family
    • Vossen CY, Hasstedt SJ, Rosendaal FR et al. Heritability of plasma concentrations of clotting factors and measures of a prethrombotic state in a protein C-deficient family. J Thromb Haemost 2004; 2: 242-247.
    • (2004) J Thromb Haemost , vol.2 , pp. 242-247
    • Vossen, C.Y.1    Hasstedt, S.J.2    Rosendaal, F.R.3
  • 24
    • 0034976945 scopus 로고    scopus 로고
    • Identification of novel polymorphisms within the protein Z gene, haplotype distribution and linkage analysis
    • Rice GI, Futers TS, Grant PJ. Identification of novel polymorphisms within the protein Z gene, haplotype distribution and linkage analysis. Thromb Haemost 2001; 85: 1123-1124.
    • (2001) Thromb Haemost , vol.85 , pp. 1123-1124
    • Rice, G.I.1    Futers, T.S.2    Grant, P.J.3
  • 25
    • 9144258392 scopus 로고    scopus 로고
    • A common polymorphism of the protein Z gene is associated with protein Z plasma levels and with risk of cerebral ischemia in the young
    • Lichy C, Kropp S, Dong-Si T et al. A common polymorphism of the protein Z gene is associated with protein Z plasma levels and with risk of cerebral ischemia in the young. Stroke 2004; 35: 40-45.
    • (2004) Stroke , vol.35 , pp. 40-45
    • Lichy, C.1    Kropp, S.2    Dong-Si, T.3
  • 26
    • 33750142791 scopus 로고    scopus 로고
    • Low protein Z levels and risk of occurrence of deep vein thrombosis
    • Santacroce R, Sarno M, Cappucci F et al. Low protein Z levels and risk of occurrence of deep vein thrombosis. J Thromb Haemost 2006; 4: 2417-2422
    • (2006) J Thromb Haemost , vol.4 , pp. 2417-2422
    • Santacroce, R.1    Sarno, M.2    Cappucci, F.3
  • 27
    • 60849106268 scopus 로고    scopus 로고
    • Haplotypic or genotypic combinations of three protein Z polymorphisms influence protein Z plasma level
    • Le Cam-Duchez V, Barbay V, Bal Dit Sollier C et al. Haplotypic or genotypic combinations of three protein Z polymorphisms influence protein Z plasma level. Thromb Haemost 2009; 101: 212-214.
    • (2009) Thromb Haemost , vol.101 , pp. 212-214
    • Le Cam-Duchez, V.1    Barbay, V.2    Bal Dit Sollier, C.3
  • 28
    • 64049097137 scopus 로고    scopus 로고
    • Association of the protein Z ATG haplotype with symptomatic nonvascular stroke or thromboembolism in white children: a family-based cohort study
    • Nowak-Göttl U, Fröhlich B, Thedieck S et al. Association of the protein Z ATG haplotype with symptomatic nonvascular stroke or thromboembolism in white children: a family-based cohort study. Blood 2009; 113: 2336-2341.
    • (2009) Blood , vol.113 , pp. 2336-2341
    • Nowak-Göttl, U.1    Fröhlich, B.2    Thedieck, S.3
  • 29
    • 20444410354 scopus 로고    scopus 로고
    • Protein Z gene polymorphisms, protein Z concentrations, and ischemic stroke
    • Staton J, Sayer M, Hankey GJ et al. Protein Z gene polymorphisms, protein Z concentrations, and ischemic stroke. Stroke 2005; 36: 1123-1127.
    • (2005) Stroke , vol.36 , pp. 1123-1127
    • Staton, J.1    Sayer, M.2    Hankey, G.J.3
  • 30
    • 12744254918 scopus 로고    scopus 로고
    • R255h amino acid substitution of protein Z identified in patients with factor V Leiden mutation
    • Kemkes-Matthes B, Matthes KJ, Souri M et al. R255h amino acid substitution of protein Z identified in patients with factor V Leiden mutation. Br J Haematol 2005; 128: 248-252.
    • (2005) Br J Haematol , vol.128 , pp. 248-252
    • Kemkes-Matthes, B.1    Matthes, K.J.2    Souri, M.3
  • 31
    • 33745627306 scopus 로고    scopus 로고
    • A nonsense polymorphism in the protein Z-dependent protease inhibitor increases the risk for venous thrombosis
    • Corral J, González-Conejero R, Soria JM et al. A nonsense polymorphism in the protein Z-dependent protease inhibitor increases the risk for venous thrombosis. Blood 2006; 108: 177-183.
    • (2006) Blood , vol.108 , pp. 177-183
    • Corral, J.1    González-Conejero, R.2    Soria, J.M.3
  • 32
    • 65349096879 scopus 로고    scopus 로고
    • Protein Z-dependent protease inhibitor and protein Z in peripheral arterial disease patients
    • Sofi F, Cesari F, Tu Y et al. Protein Z-dependent protease inhibitor and protein Z in peripheral arterial disease patients. J Thromb Haemost 2009; 7: 731-735.
    • (2009) J Thromb Haemost , vol.7 , pp. 731-735
    • Sofi, F.1    Cesari, F.2    Tu, Y.3
  • 33
    • 0026615279 scopus 로고
    • 2+ binding properties of the gamma-carboxyglutamic acid-containing module of protein Z in the intact protein and in N-terminal fragments
    • 2+ binding properties of the gamma-carboxyglutamic acid-containing module of protein Z in the intact protein and in N-terminal fragments. FEBS Lett 1992; 314: 5-9.
    • (1992) FEBS Lett , vol.314 , pp. 5-9
    • Persson, E.1    Stenflo, J.2
  • 34
    • 0025243491 scopus 로고
    • Amino acid sequence of human protein Z, a vitamin K-dependent plasma glycoprotein
    • Ichinose A, Takeya H, Espling E et al. Amino acid sequence of human protein Z, a vitamin K-dependent plasma glycoprotein. Biochem Biophys Res Commun 1990; 172: 1139-1144.
    • (1990) Biochem Biophys Res Commun , vol.172 , pp. 1139-1144
    • Ichinose, A.1    Takeya, H.2    Espling, E.3
  • 35
    • 50649096216 scopus 로고    scopus 로고
    • Protein Z-dependent protease inhibitor binds to the C-terminal domain of protein Z
    • Rezaie AR, Bae JS, Manithody C et al. Protein Z-dependent protease inhibitor binds to the C-terminal domain of protein Z. J Biol Chem 2008; 283: 19922-19926.
    • (2008) J Biol Chem , vol.283 , pp. 19922-19926
    • Rezaie, A.R.1    Bae, J.S.2    Manithody, C.3
  • 36
    • 70449572365 scopus 로고    scopus 로고
    • Crystal structure of protein Z-dependent inhibitor complex shows how protein Z functions as a cofactor in the membrane inhibition of factor X
    • Wei Z, Yan Y, Carrell RW et al. Crystal structure of protein Z-dependent inhibitor complex shows how protein Z functions as a cofactor in the membrane inhibition of factor X. Blood 2009; 114: 3662-3667.
    • (2009) Blood , vol.114 , pp. 3662-3667
    • Wei, Z.1    Yan, Y.2    Carrell, R.W.3
  • 37
    • 77953741281 scopus 로고    scopus 로고
    • Basis for the specificity and activation of the serpin protein Z-dependent proteinase inhibitor (ZPI) as an inhibitor of membrane-associated factor Xa
    • Huang X, Dementiev A, Olson ST et al. Basis for the specificity and activation of the serpin protein Z-dependent proteinase inhibitor (ZPI) as an inhibitor of membrane-associated factor Xa. J Biol Chem 2010; 285: 20399-20409.
    • (2010) J Biol Chem , vol.285 , pp. 20399-20409
    • Huang, X.1    Dementiev, A.2    Olson, S.T.3
  • 38
    • 0033600562 scopus 로고    scopus 로고
    • The protein Z-dependent protease inhibitor is a serpin
    • Han X, Huang ZF, Fiehler R et al. The protein Z-dependent protease inhibitor is a serpin. Biochemistry 1999; 38: 11073-11078.
    • (1999) Biochemistry , vol.38 , pp. 11073-11078
    • Han, X.1    Huang, Z.F.2    Fiehler, R.3
  • 39
    • 57649233041 scopus 로고    scopus 로고
    • Kinetic characterization of the protein Z-dependent protease inhibitor reaction with blood coagulation factor Xa
    • Huang X, Swanson R, Broze GJ Jr et al. Kinetic characterization of the protein Z-dependent protease inhibitor reaction with blood coagulation factor Xa. J Biol Chem 2008; 283: 29770-29783.
    • (2008) J Biol Chem , vol.283 , pp. 29770-29783
    • Huang, X.1    Swanson, R.2    Broze Jr., G.J.3
  • 40
    • 79953167472 scopus 로고    scopus 로고
    • Heparin is a major activator of the anticoagulant serpin, protein Z-dependent protease inhibitor
    • Huang X, Rezaie AR, Broze GJ Jr et al. Heparin is a major activator of the anticoagulant serpin, protein Z-dependent protease inhibitor. J Biol Chem 2011; 286: 8740-8751.
    • (2011) J Biol Chem , vol.286 , pp. 8740-8751
    • Huang, X.1    Rezaie, A.R.2    Broze Jr., G.J.3
  • 41
    • 25444475057 scopus 로고    scopus 로고
    • Identification of factor Xa residues critical for interaction with protein Z-dependent protease inhibitor: both active site and exosite interactions are required for inhibition
    • Rezaie AR, Manithody C, Yang L. Identification of factor Xa residues critical for interaction with protein Z-dependent protease inhibitor: both active site and exosite interactions are required for inhibition. J Biol Chem 2005; 280: 32722-32728.
    • (2005) J Biol Chem , vol.280 , pp. 32722-32728
    • Rezaie, A.R.1    Manithody, C.2    Yang, L.3
  • 42
    • 0035942002 scopus 로고    scopus 로고
    • Frequency of protein Z deficiency in patients with ischaemic stroke
    • Vasse M, Guegan-Massardier E, Borg JY et al. Frequency of protein Z deficiency in patients with ischaemic stroke. Lancet 2001; 357: 933-934.
    • (2001) Lancet , vol.357 , pp. 933-934
    • Vasse, M.1    Guegan-Massardier, E.2    Borg, J.Y.3
  • 43
    • 0037092632 scopus 로고    scopus 로고
    • Protein Z influences the prothrombotic phenotype in factor V Leiden patients
    • Kemkes-Matthes B, Nees M, Kühnel G et al. Protein Z influences the prothrombotic phenotype in factor V Leiden patients. Thromb Res 2002; 106: 183-185.
    • (2002) Thromb Res , vol.106 , pp. 183-185
    • Kemkes-Matthes, B.1    Nees, M.2    Kühnel, G.3
  • 44
    • 41749120573 scopus 로고    scopus 로고
    • Protein Z levels and anti-protein Z antibodies in patients with arterial and venous thrombosis
    • Pardos-Gea J, Ordi-Ros J, Serrano S et al. Protein Z levels and anti-protein Z antibodies in patients with arterial and venous thrombosis. Thromb Res 2008; 121: 727-734.
    • (2008) Thromb Res , vol.121 , pp. 727-734
    • Pardos-Gea, J.1    Ordi-Ros, J.2    Serrano, S.3
  • 45
    • 29244465864 scopus 로고    scopus 로고
    • Low levels of protein Z and the risk of venous thromboembolism
    • Martinelli I, Razzari C, Biguzzi E et al. Low levels of protein Z and the risk of venous thromboembolism. J Thromb Haemost 2005; 3: 2817-2819.
    • (2005) J Thromb Haemost , vol.3 , pp. 2817-2819
    • Martinelli, I.1    Razzari, C.2    Biguzzi, E.3
  • 46
    • 0042657717 scopus 로고    scopus 로고
    • Low protein Z levels and risk of ischemic stroke: differences by diabetic status and gender
    • Heeb MJ, Paganini-Hill A, Griffin JH et al. Low protein Z levels and risk of ischemic stroke: differences by diabetic status and gender. Blood Cells Mol Dis 2002; 29: 139-144.
    • (2002) Blood Cells Mol Dis , vol.29 , pp. 139-144
    • Heeb, M.J.1    Paganini-Hill, A.2    Griffin, J.H.3
  • 47
    • 0033560668 scopus 로고    scopus 로고
    • Plasma protein Z levels inversely correlate with plasma interleukin-6 levels in patients with acute leukemia and non-Hodgkin's lymphoma
    • Undar L, Karadogan I, Oztürk F. Plasma protein Z levels inversely correlate with plasma interleukin-6 levels in patients with acute leukemia and non-Hodgkin's lymphoma. Thromb Res 1999; 94: 131-134.
    • (1999) Thromb Res , vol.94 , pp. 131-134
    • Undar, L.1    Karadogan, I.2    Oztürk, F.3
  • 48
    • 0141530977 scopus 로고    scopus 로고
    • Protein Z in ischemic stroke and its etiologic subtypes
    • McQuillan AM, Eikelboom JW, Hankey GJ et al. Protein Z in ischemic stroke and its etiologic subtypes. Stroke 2003; 34: 2415-2419.
    • (2003) Stroke , vol.34 , pp. 2415-2419
    • McQuillan, A.M.1    Eikelboom, J.W.2    Hankey, G.J.3
  • 49
    • 33746665242 scopus 로고    scopus 로고
    • Protein Z gene polymorphisms (intron F 79 G>A; -13 A>G) are not associated with acute coronary syndromes
    • Cesari F, Fatini C, Sticchi E et al. Protein Z gene polymorphisms (intron F 79 G>A; -13 A>G) are not associated with acute coronary syndromes. Thromb Haemost 2006; 96: 98-99.
    • (2006) Thromb Haemost , vol.96 , pp. 98-99
    • Cesari, F.1    Fatini, C.2    Sticchi, E.3
  • 50
    • 67749106111 scopus 로고    scopus 로고
    • Rare genotypes of protein Z gene are a risk factor for premature myocardial infarction but not protein Z plasma level
    • Le Cam-Duchez V, Soria C, Dit Sollier CB et al. Rare genotypes of protein Z gene are a risk factor for premature myocardial infarction but not protein Z plasma level. Thromb Haemost 2009; 102: 131-136.
    • (2009) Thromb Haemost , vol.102 , pp. 131-136
    • Le Cam-Duchez, V.1    Soria, C.2    Dit Sollier, C.B.3
  • 51
    • 79952746175 scopus 로고    scopus 로고
    • Genes associated with adult cerebral venous thrombosis
    • Marjot T, Yadav S, Hasan N et al. Genes associated with adult cerebral venous thrombosis. Stroke 2011; 42: 913-918.
    • (2011) Stroke , vol.42 , pp. 913-918
    • Marjot, T.1    Yadav, S.2    Hasan, N.3
  • 52
    • 56349172087 scopus 로고    scopus 로고
    • The G79A polymorphism of protein Z gene is an independent risk factor for cerebral venous thrombosis
    • Le Cam-Duchez V, Bagan-Triquenot A, Barbay V et al. The G79A polymorphism of protein Z gene is an independent risk factor for cerebral venous thrombosis. J Neurol 2008; 255: 1521-1525.
    • (2008) J Neurol , vol.255 , pp. 1521-1525
    • Le Cam-Duchez, V.1    Bagan-Triquenot, A.2    Barbay, V.3
  • 53
    • 33745289088 scopus 로고    scopus 로고
    • Protein Z and ZPI levels and cardiovascular events
    • Refaai MA, Ahn C, Lu L et al. Protein Z and ZPI levels and cardiovascular events. J Thromb Haemost 2006; 4: 1628-1629.
    • (2006) J Thromb Haemost , vol.4 , pp. 1628-1629
    • Refaai, M.A.1    Ahn, C.2    Lu, L.3
  • 54
    • 5644235083 scopus 로고    scopus 로고
    • Mutations within the protein Z-dependent protease inhibitor gene are associated with venous thromboembolic disease: a new form of thrombophilia
    • Van de Water N, Tan T, Ashton F et al. Mutations within the protein Z-dependent protease inhibitor gene are associated with venous thromboembolic disease: a new form of thrombophilia. Br J Haematol 2004; 127: 190-194.
    • (2004) Br J Haematol , vol.127 , pp. 190-194
    • Van de Water, N.1    Tan, T.2    Ashton, F.3
  • 55
    • 33646466168 scopus 로고    scopus 로고
    • Polymorphisms of the protein Z-dependent protease inhibitor (ZPI) gene and the risk of venous thromboembolism
    • Razzari C, Martinelli I, Bucciarelli P et al. Polymorphisms of the protein Z-dependent protease inhibitor (ZPI) gene and the risk of venous thromboembolism. Thromb Haemost 2006; 95: 909-910.
    • (2006) Thromb Haemost , vol.95 , pp. 909-910
    • Razzari, C.1    Martinelli, I.2    Bucciarelli, P.3
  • 56
    • 52649152263 scopus 로고    scopus 로고
    • Polymorphisms of the Z protein protease inhibitor and risk of venous thromboembolism: a meta-analysis
    • Dentali F, Gianni M, Lussana F et al. Polymorphisms of the Z protein protease inhibitor and risk of venous thromboembolism: a meta-analysis. Br J Haematol 2008; 143: 284-287.
    • (2008) Br J Haematol , vol.143 , pp. 284-287
    • Dentali, F.1    Gianni, M.2    Lussana, F.3
  • 57
    • 0036529843 scopus 로고    scopus 로고
    • High frequency of protein Z deficiency in patients with unexplained early fetal loss
    • Gris JC, Quéré I, Dechaud H et al. High frequency of protein Z deficiency in patients with unexplained early fetal loss. Blood 2002; 99: 2606-2608.
    • (2002) Blood , vol.99 , pp. 2606-2608
    • Gris, J.C.1    Quéré, I.2    Dechaud, H.3
  • 58
    • 33748531805 scopus 로고    scopus 로고
    • Tissue microarray: an effective high-throughput method to study the placenta for clinical and research purposes
    • Richani K, Romero R, Kim YM et al. Tissue microarray: an effective high-throughput method to study the placenta for clinical and research purposes. J Matern Fetal Neonatal Med 2006; 19: 509-515.
    • (2006) J Matern Fetal Neonatal Med , vol.19 , pp. 509-515
    • Richani, K.1    Romero, R.2    Kim, Y.M.3
  • 59
    • 53149152221 scopus 로고    scopus 로고
    • Pyelonephritis during pregnancy: a cause for an acquired deficiency of protein Z
    • Nien JK, Romero R, Hoppensteadt D et al. Pyelonephritis during pregnancy: a cause for an acquired deficiency of protein Z. J Matern Fetal Neonatal Med 2008; 21: 629-637.
    • (2008) J Matern Fetal Neonatal Med , vol.21 , pp. 629-637
    • Nien, J.K.1    Romero, R.2    Hoppensteadt, D.3
  • 60
    • 5144228347 scopus 로고    scopus 로고
    • Protein Z levels and unexplained fetal losses
    • Grandone E, Colaizzo D, Cappucci F et al. Protein Z levels and unexplained fetal losses. Fertil Steril 2004; 82: 982-983.
    • (2004) Fertil Steril , vol.82 , pp. 982-983
    • Grandone, E.1    Colaizzo, D.2    Cappucci, F.3
  • 61
    • 10744230738 scopus 로고    scopus 로고
    • Anti-protein Z antibodies in women with pathologic pregnancies
    • Gris JC, Amadio C, Mercier E et al. Anti-protein Z antibodies in women with pathologic pregnancies. Blood 2003; 101: 4850-4852.
    • (2003) Blood , vol.101 , pp. 4850-4852
    • Gris, J.C.1    Amadio, C.2    Mercier, E.3
  • 62
    • 79953676853 scopus 로고    scopus 로고
    • High frequency of anti-protein Z IgM and IgG autoantibodies in women with idiopathic recurrent spontaneous miscarriage
    • Sater MS, Finan RR, Al-Hammad SA et al. High frequency of anti-protein Z IgM and IgG autoantibodies in women with idiopathic recurrent spontaneous miscarriage. Am J Reprod Immunol 2011; 65: 526-531.
    • (2011) Am J Reprod Immunol , vol.65 , pp. 526-531
    • Sater, M.S.1    Finan, R.R.2    Al-Hammad, S.A.3
  • 63
    • 44449118967 scopus 로고    scopus 로고
    • Clinical significance of anti-protein Z antibodies in patients with lupus anticoagulant
    • Sailer T, Vormittag R, Koder S et al. Clinical significance of anti-protein Z antibodies in patients with lupus anticoagulant. Thromb Res 2008; 122: 153-160.
    • (2008) Thromb Res , vol.122 , pp. 153-160
    • Sailer, T.1    Vormittag, R.2    Koder, S.3
  • 64
    • 70350666477 scopus 로고    scopus 로고
    • Maternal antiprotein Z antibodies in pregnancies complicated by pre-eclampsia, SGA and fetal death
    • Erez O, Romero R, Vaisbuch E et al. Maternal antiprotein Z antibodies in pregnancies complicated by pre-eclampsia, SGA and fetal death. J Matern Fetal Neonatal Med 2009; 22: 662-671.
    • (2009) J Matern Fetal Neonatal Med , vol.22 , pp. 662-671
    • Erez, O.1    Romero, R.2    Vaisbuch, E.3
  • 65
    • 2342633147 scopus 로고    scopus 로고
    • Low-molecular-weight heparin versus low-dose aspirin in women with one fetal loss and a constitutional thrombophilic disorder
    • Gris JC, Mercier E, Quéré I et al. Low-molecular-weight heparin versus low-dose aspirin in women with one fetal loss and a constitutional thrombophilic disorder. Blood 2004; 103: 3695-3699.
    • (2004) Blood , vol.103 , pp. 3695-3699
    • Gris, J.C.1    Mercier, E.2    Quéré, I.3
  • 66
    • 52949094675 scopus 로고    scopus 로고
    • Association of the protein Z intron F G79A gene polymorphism with recurrent pregnancy loss
    • Dossenbach-Glaninger A, van Trotsenburg M, Helmer H et al. Association of the protein Z intron F G79A gene polymorphism with recurrent pregnancy loss. Fertil Steril 2008; 90: 1155-1160.
    • (2008) Fertil Steril , vol.90 , pp. 1155-1160
    • Dossenbach-Glaninger, A.1    van Trotsenburg, M.2    Helmer, H.3
  • 67
    • 80053591754 scopus 로고    scopus 로고
    • Relationship of the protein Z intron F G79A and IL6 C634G gene polymorphisms with the risk of recurrent pregnancy loss in Egyptian women
    • El-Hamid SA, El-Khayat W. Relationship of the protein Z intron F G79A and IL6 C634G gene polymorphisms with the risk of recurrent pregnancy loss in Egyptian women. J Investig Med 2011.
    • (2011) J Investig Med
    • El-Hamid, S.A.1    El-Khayat, W.2
  • 68
    • 64549164580 scopus 로고    scopus 로고
    • Low protein Z levels, but not the intron F G79A polymorphism, are associated with unexplained pregnancy loss
    • Topalidou M, Effraimidou S, Farmakiotis D et al. Low protein Z levels, but not the intron F G79A polymorphism, are associated with unexplained pregnancy loss. Thromb Res 2009; 124: 24-27.
    • (2009) Thromb Res , vol.124 , pp. 24-27
    • Topalidou, M.1    Effraimidou, S.2    Farmakiotis, D.3
  • 69
    • 51449085317 scopus 로고    scopus 로고
    • An unreported mutation within protein Z gene is associated with very low protein levels in women with fetal loss
    • Grandone E, Colaizzo D, Cappucci F et al. An unreported mutation within protein Z gene is associated with very low protein levels in women with fetal loss. Fertil Steril 2008; 90: 864-865.
    • (2008) Fertil Steril , vol.90 , pp. 864-865
    • Grandone, E.1    Colaizzo, D.2    Cappucci, F.3
  • 70
    • 63249123194 scopus 로고    scopus 로고
    • Protein Z g-42a variant and the risk of pregnancy-related venous thromboembolism in a cohort of Italian patients
    • Grandone E, Favuzzi G, De Stefano V et al. Protein Z g-42a variant and the risk of pregnancy-related venous thromboembolism in a cohort of Italian patients. Thromb Res 2009; 123: 848-850.
    • (2009) Thromb Res , vol.123 , pp. 848-850
    • Grandone, E.1    Favuzzi, G.2    De Stefano, V.3
  • 71
    • 0346903191 scopus 로고    scopus 로고
    • Low protein Z plasma levels are independently associated with acute coronary syndromes
    • Fedi S, Sofi F, Brogi D, Tellini I et al. Low protein Z plasma levels are independently associated with acute coronary syndromes. Thromb Haemost 2003; 90: 1173-1178.
    • (2003) Thromb Haemost , vol.90 , pp. 1173-1178
    • Fedi, S.1    Sofi, F.2    Brogi, D.3    Tellini, I.4
  • 72
    • 33845879901 scopus 로고    scopus 로고
    • Modifications of protein Z and interleukin-6 during the acute phase of coronary artery disease
    • Cesari F, Gori AM, Fedi S et al. Modifications of protein Z and interleukin-6 during the acute phase of coronary artery disease. Blood Coagul Fibrinolysis 2007; 18: 85-86.
    • (2007) Blood Coagul Fibrinolysis , vol.18 , pp. 85-86
    • Cesari, F.1    Gori, A.M.2    Fedi, S.3
  • 73
    • 33645544034 scopus 로고    scopus 로고
    • Human endothelial cells synthesize protein Z, but not the protein Z dependent inhibitor
    • Vasse M, Denoyelle C, Corbière C et al. Human endothelial cells synthesize protein Z, but not the protein Z dependent inhibitor. Thromb Haemost 2006; 95: 519-523.
    • (2006) Thromb Haemost , vol.95 , pp. 519-523
    • Vasse, M.1    Denoyelle, C.2    Corbière, C.3
  • 74
    • 0034923318 scopus 로고    scopus 로고
    • Protein Z-dependent regulation of coagulation
    • Broze GJ Jr. Protein Z-dependent regulation of coagulation. Thromb Haemost 2001; 86: 8-13.
    • (2001) Thromb Haemost , vol.86 , pp. 8-13
    • Broze Jr., G.J.1
  • 75
    • 0036901177 scopus 로고    scopus 로고
    • Correlation of serum IL-2, IL-6 and IL-10 levels with International Prognostic Index in patients with aggressive non-Hodgkin's lymphoma
    • Aydin F, Yilmaz M, Ozdemir F et al. Correlation of serum IL-2, IL-6 and IL-10 levels with International Prognostic Index in patients with aggressive non-Hodgkin's lymphoma. Am J Clin Oncol 2002; 25: 570-572.
    • (2002) Am J Clin Oncol , vol.25 , pp. 570-572
    • Aydin, F.1    Yilmaz, M.2    Ozdemir, F.3
  • 76
    • 59649118459 scopus 로고    scopus 로고
    • Identifying cancer patients at risk for venous thromboembolism
    • Sousou T, Khorana A. Identifying cancer patients at risk for venous thromboembolism. Hamostaseologie 2009; 29: 121-124.
    • (2009) Hamostaseologie , vol.29 , pp. 121-124
    • Sousou, T.1    Khorana, A.2
  • 77
    • 34548099426 scopus 로고    scopus 로고
    • Clinical significance of protein Z detection in patients with malignant tumors
    • Shang Y, Pan XY, Ding CP et al. Clinical significance of protein Z detection in patients with malignant tumors. Ai Zheng 2005; 24: 1144-1147.
    • (2005) Ai Zheng , vol.24 , pp. 1144-1147
    • Shang, Y.1    Pan, X.Y.2    Ding, C.P.3
  • 78
    • 34547812138 scopus 로고    scopus 로고
    • Coagulation-related factors, thrombomodulin and protein Z, are not associated with risk for oral cancer
    • Vairaktaris E, Serefoglou Z, Yapijakis C et al. Coagulation-related factors, thrombomodulin and protein Z, are not associated with risk for oral cancer. Anticancer Res 2007; 27: 2449-2451.
    • (2007) Anticancer Res , vol.27 , pp. 2449-2451
    • Vairaktaris, E.1    Serefoglou, Z.2    Yapijakis, C.3
  • 79
    • 62149083774 scopus 로고    scopus 로고
    • Intron F G79A polymorphism of the protein Z gene in cancer patients with and without thrombosis
    • Eroglu A, Ozturk A, Cam R et al. Intron F G79A polymorphism of the protein Z gene in cancer patients with and without thrombosis. J Thromb Thrombolysis 2009; 27: 204-206.
    • (2009) J Thromb Thrombolysis , vol.27 , pp. 204-206
    • Eroglu, A.1    Ozturk, A.2    Cam, R.3
  • 80
    • 33745092361 scopus 로고    scopus 로고
    • Gene expression profiles of progressive pancreatic endocrine tumours and their liver metastases reveal potential novel markers and therapeutic targets
    • Capurso G, Lattimore S, Crnogorac-Jurcevic T et al. Gene expression profiles of progressive pancreatic endocrine tumours and their liver metastases reveal potential novel markers and therapeutic targets. Endocr Relat Cancer 2006; 13: 541-558.
    • (2006) Endocr Relat Cancer , vol.13 , pp. 541-558
    • Capurso, G.1    Lattimore, S.2    Crnogorac-Jurcevic, T.3
  • 81
    • 59149090670 scopus 로고    scopus 로고
    • Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas
    • Leja J, Essaghir A, Essand M et al. Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas. Mod Pathol 2009; 22: 261-272.
    • (2009) Mod Pathol , vol.22 , pp. 261-272
    • Leja, J.1    Essaghir, A.2    Essand, M.3
  • 82
    • 77954372982 scopus 로고    scopus 로고
    • Protein Z-dependent protease inhibitor (ZPI) is present in loco in human breast cancer tissue
    • Sierko E, Wojtukiewicz MZ, Ostrowska-Cichocka K et al. Protein Z-dependent protease inhibitor (ZPI) is present in loco in human breast cancer tissue. Thromb Haemost 2010; 104: 183-185.
    • (2010) Thromb Haemost , vol.104 , pp. 183-185
    • Sierko, E.1    Wojtukiewicz, M.Z.2    Ostrowska-Cichocka, K.3
  • 83
    • 80052910986 scopus 로고    scopus 로고
    • Protein Z is present in human breast cancer tissue
    • doi 10.1007/s12185-011-0846-3
    • Sierko E, Wojtukiewicz MZ, Zimnoch L et al. Protein Z is present in human breast cancer tissue. Int J Hematol 2011: doi 10.1007/s12185-011-0846-3.
    • (2011) Int J Hematol
    • Sierko, E.1    Wojtukiewicz, M.Z.2    Zimnoch, L.3
  • 84
    • 75749131631 scopus 로고    scopus 로고
    • Protein Z and protein Z-dependent protease inhibitor and renal tubules
    • Broze GJ Jr, Tu Y. Protein Z and protein Z-dependent protease inhibitor and renal tubules. Thromb Haemost 2010; 103: 473-474.
    • (2010) Thromb Haemost , vol.103 , pp. 473-474
    • Broze Jr., G.J.1    Tu, Y.2
  • 85
    • 0345731214 scopus 로고    scopus 로고
    • Detection of protein Z in a renal calculus composed of calcium oxalate monohydrate with the use of liquid chromatography-mass spectrometry/mass spectrometry following two-dimensional polyacrylamide gel electrophoresis separation
    • Kaneko K, Yamanobe T, Nakagomi K et al. Detection of protein Z in a renal calculus composed of calcium oxalate monohydrate with the use of liquid chromatography-mass spectrometry/mass spectrometry following two-dimensional polyacrylamide gel electrophoresis separation. Anal Biochem 2004; 324: 191-196.
    • (2004) Anal Biochem , vol.324 , pp. 191-196
    • Kaneko, K.1    Yamanobe, T.2    Nakagomi, K.3
  • 86
    • 77956580017 scopus 로고    scopus 로고
    • Proteomic signatures in plasma during early acute renal allograft rejection
    • Freue GV, Sasaki M, Meredith A et al. Proteomic signatures in plasma during early acute renal allograft rejection. Mol Cell Proteomics 2010; 9: 1954-1967.
    • (2010) Mol Cell Proteomics , vol.9 , pp. 1954-1967
    • Freue, G.V.1    Sasaki, M.2    Meredith, A.3
  • 87
    • 0033807066 scopus 로고    scopus 로고
    • Complete antithrombin deficiency in mice results in embryonic lethality
    • Ishiguro K, Kojima T, Kadomatsu K et al. Complete antithrombin deficiency in mice results in embryonic lethality. J Clin Invest 2000; 106: 873-878.
    • (2000) J Clin Invest , vol.106 , pp. 873-878
    • Ishiguro, K.1    Kojima, T.2    Kadomatsu, K.3
  • 88
    • 0032532678 scopus 로고    scopus 로고
    • Inactivation of the gene for anticoagulant protein C causes lethal perinatal consumptive coagulopathy in mice
    • Jalbert LR, Rosen ED, Moons L et al. Inactivation of the gene for anticoagulant protein C causes lethal perinatal consumptive coagulopathy in mice. J Clin Invest 1998; 102: 1481-1488.
    • (1998) J Clin Invest , vol.102 , pp. 1481-1488
    • Jalbert, L.R.1    Rosen, E.D.2    Moons, L.3
  • 89
    • 70349575804 scopus 로고    scopus 로고
    • Generation and phenotypic analysis of protein S-deficient mice
    • Saller F, Brisset AC, Tchaikovski SN et al. Generation and phenotypic analysis of protein S-deficient mice. Blood 2009; 114: 2307-2314.
    • (2009) Blood , vol.114 , pp. 2307-2314
    • Saller, F.1    Brisset, A.C.2    Tchaikovski, S.N.3
  • 90
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis - an inflammatory disease
    • Ross R. Atherosclerosis - an inflammatory disease. N Engl J Med 1999; 340: 115-126.
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 91
    • 0035707639 scopus 로고    scopus 로고
    • Regulation of inflammatory responses by natural anticoagulants
    • Okajima K. Regulation of inflammatory responses by natural anticoagulants. Immunol Rev 2001; 184: 258-274.
    • (2001) Immunol Rev , vol.184 , pp. 258-274
    • Okajima, K.1
  • 92
    • 78249290243 scopus 로고    scopus 로고
    • Fibrinogen promotes early atherosclerotic changes of the carotid artery in young, healthy adults
    • Grebe MT, Luu B, Sedding D et al. Fibrinogen promotes early atherosclerotic changes of the carotid artery in young, healthy adults. J Atheroscler Thromb 2010; 17: 1003-1008.
    • (2010) J Atheroscler Thromb , vol.17 , pp. 1003-1008
    • Grebe, M.T.1    Luu, B.2    Sedding, D.3
  • 93
    • 0031928206 scopus 로고    scopus 로고
    • Localisation of protein Z in vascular lesions of patients with atherosclerosis
    • Greten J, Kreis I, Liliensiek B et al. Localisation of protein Z in vascular lesions of patients with atherosclerosis. Vasa 1998; 27: 144-148.
    • (1998) Vasa , vol.27 , pp. 144-148
    • Greten, J.1    Kreis, I.2    Liliensiek, B.3
  • 94
    • 0014575169 scopus 로고
    • Plasminogen activator activity in cultures from human tissues. An immunological and histochemical study
    • Bernik MB, Kwaan HC. Plasminogen activator activity in cultures from human tissues. An immunological and histochemical study. J Clin Invest 1969; 48: 1740-1753.
    • (1969) J Clin Invest , vol.48 , pp. 1740-1753
    • Bernik, M.B.1    Kwaan, H.C.2
  • 95
    • 65249116364 scopus 로고    scopus 로고
    • Regulation of arterial remodeling and angiogenesis by urokinase-type plasminogen activator
    • Tkachuk VA, Plekhanova OS, Parfyonova YV. Regulation of arterial remodeling and angiogenesis by urokinase-type plasminogen activator. Can J Physiol Pharmacol 2009; 87: 231-251.
    • (2009) Can J Physiol Pharmacol , vol.87 , pp. 231-251
    • Tkachuk, V.A.1    Plekhanova, O.S.2    Parfyonova, Y.V.3
  • 96
    • 23944512466 scopus 로고    scopus 로고
    • Tumor-associated prognostic factors of the plasminogen activator family: determination and clinical value of u-PA, t-PA, PAI-1, and PAI-2
    • Mengele K, Harbeck N, Reuning U et al. Tumor-associated prognostic factors of the plasminogen activator family: determination and clinical value of u-PA, t-PA, PAI-1, and PAI-2. Hämostaseologie 2005; 25: 301-310.
    • (2005) Hämostaseologie , vol.25 , pp. 301-310
    • Mengele, K.1    Harbeck, N.2    Reuning, U.3


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