Protein Z gene polymorphisms are associated with protein Z plasma levels [4]

Journal of Thrombosis and Haemostasis

Volumn 2, Issue 7, 2004, Pages 1197-1199

  Santacroce, R ^a   Cappucci, F ^b   di Perna, P ^b   Sessa, F ^a   Margaglione, Maurizio ^a  

^a UNIVERSITY OF FOGGIA   (Italy)

^b CASA SOLLIEVO DELLA SOFFERENZA HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; DNA; DNA FRAGMENT; FATTY ACID BINDING PROTEIN;

ADULT; AGED; BLEEDING; BLOOD SAMPLING; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; DNA EXTRACTION; ENZYME LINKED IMMUNOSORBENT ASSAY; EXON; FEMALE; FETUS WASTAGE; GENE EXPRESSION; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HEREDITY; HETEROZYGOSITY; HUMAN; INTRON; ITALY; LETTER; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; POPULATION RESEARCH; PRIORITY JOURNAL; PROTEIN ANALYSIS; SEQUENCE ANALYSIS;

ADULT; AGED; BLOOD PROTEINS; FEMALE; GENE FREQUENCY; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; REFERENCE VALUES;

EID: 13244289834     PISSN: 15387933     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2004.00808.x     Document Type: Letter

References (15)

1. Broze GJ Jr. Protein Z dependent regulation of coagulation. Thromb Haemost 2001; 86: 8-13.
2. Kemkes-Matthes B, Matthes KJ. Protein Z deficiency: a new cause of bleeding tendency. Thromb Res 1995; 79: 49-55.
3. Yin ZF, Huang ZF, Cui J, Fiehler R, Lasky N, Ginsburg D, Broze GJ Jr. Prothrombotic phenotype of protein Z deficiency. Proc Natl Acad Sci USA 2000; 97: 6734-8.
4. Kemkes-Matthes B, Nees M, Kuhnel G, Matzdorff A, Matthes KJ. Protein Z influences prothrombotic phenotype of factor V Leiden in humans. Thromb Res 2002; 106: 183-5.
5. Gris JC, Quéré I, Dechaud H, Mercier E, Pincon C, Hoffet M, Vasse M, Mares P. High frequency of protein Z deficiency in patients with unexplained early fetal loss. Blood 2002; 99: 2606-8.
6. Ravi S, Mauron T, Lämmle B, Wuillemin WA. Protein Z in healthy human individuals and in patients with bleeding tendency. Br J Haematol 1998; 102: 1219-23.
7. Vasse M, Guegan-Massardier E, Borg JY, Woimant F, Soria C. Frequency of protein Z deficiency in patients with ischemic stroke. Lancet 2001; 357: 933-4.
8. Hopmeier P, van Trotsemburg M, Dossenbach-Glanicher A. Recurrent pregnancy loss between the 8th and the 15th week of gestation is not associated with an increased frequency of protein Z deficiency. J Thromb Haemost 2003; 1 (Suppl.): P0865 [Abstract].
9. Rice GI, Futers TS, Grant PJ. Identification of novel polymorphisms within the protein Z gene, haplotype distribution and linkage analysis. Thromb Haemost 2001; 85: 1123-4.
10. 20210 gene variant. Ann Intern Med 1998; 129: 89-93.
11. Miletich JP, Broze GJ Jr. Human plasma protein Z antigen: range in normal subjects and effects of warfarin therapy. Blood 1987; 69: 1580-6.
12. McQuillan AM, Eikelboom JW, Hankey GJ, Baker R, Thom J, Staton J, Yi Q, Cole V. Protein Z in ischemic stroke and its etiologic subtypes. Stroke 2003; 34: 2415-9.
13. Sofi F, Fedi S, Tellini I, Cesari F, De Brogi D, Marcucci R, Prisco D, Pepe G, Abbate R, Gensini GF. Protein Z levels in acute coronary syndromes. J Thromb Haemost 2003; 1 (Suppl.): P0507 [Abstract].
14. Vasse M, Denoyelle C, Legrand E, Vannier JP, Soria C. Weak regulation of protein Z biosynthesis by inflammatory cytokines. Thromb Haemost 2002; 87: 350-1.
15. Lichy C, Kropp S, Dong-Si T, Genius J, Dolan T, Hampe T, Stoll F, Renner K, Grond-Ginsbach C, Grau A. A common polymorphism of the protein Z gene is associated with protein Z plasma levels and with risk of cerebral ischemia in the young. Stroke 2004; 35: 40-5.