Intron F G79a polymorphism of the protein Z gene in cancer patients with and without thrombosis

Journal of Thrombosis and Thrombolysis

Volumn 27, Issue 2, 2009, Pages 204-206

  Eroglu, Aydan ^a   Ozturk, Aysenur ^b   Çam, Ragip ^b   Akar, Nejat ^b  

^a Numune State Hospital   (Turkey)

^b ANKARA UNIVERSITY   (Turkey)

Author keywords

Cancer; Polymorphism; Protein Z gene; Thrombosis

Indexed keywords

BLOOD CLOTTING FACTOR 5 LEIDEN; FATTY ACID BINDING PROTEIN; PROTHROMBIN;

ADULT; ALLELE; ARTICLE; CANCER PATIENT; CLINICAL ARTICLE; CONTROLLED STUDY; DNA DETERMINATION; FEMALE; GENE FREQUENCY; GENE MUTATION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HUMAN; INTRON; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; VEIN THROMBOSIS;

ADOLESCENT; ADULT; AGED; BLOOD PROTEINS; DNA MUTATIONAL ANALYSIS; FACTOR V; FEMALE; GENOTYPE; HUMANS; INTRONS; MALE; MIDDLE AGED; NEOPLASMS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTHROMBIN; THROMBOPHILIA; THROMBOSIS; YOUNG ADULT;

EID: 62149083774     PISSN: 09295305     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11239-008-0199-9     Document Type: Article

References (10)

1. Vasse M, Guegan-Massardier E, Burg JY, Woimant F, Soria C (2001) Frequency of protein Z deficiency in patients with ischemic stroke. Lancet 357:933-934
2. Kemkes-Matthes B, Nees M, Kuhnel G, Matzdorff A, Matthes KJ (2002) Protein Z influences prothrombotic phenotype of factor V Leiden in humans. Thromb Res 106:183-185
3. Santacroce R, Sarno M, Cappucci F, Sessa F, Colaizzo D, Brancaccio V, Grandone E, Margaglione M (2006) Low protein Z levels and risk of occurrence of deep vein thrombosis. J Thromb Haemost 4:2417-2422
4. Al-Shanquetti A, van Hylckama Vlieg A, Berntorp E, Rosendaal FR, Broze GJ Jr (2005) Protein Z and protein Z-dependent protease inhibitor. Determinants of levels and risk of venous thrombosis. Thromb Haemost 93:411-413
5. Martinelli I, Razzari C, Biguzzi E, Bucciarelli P, Mannucci PM (2005) Low levels of protein Z and the risk of venous thromboembolism. J Thromb Haemost 3:2817-2819
6. Rice GI, Futers TS, Grant PJ (2001) Identification of novel polymorphisms within the protein Z gene, haplotype distribution and linkage analysis. Thromb Haemost 85:1023-1024
7. Lichy C, Kropp S, Dong-Si T, Genius J, Dolan T, Hampe T, Stoll F, Reuner K, Grond-Ginsbach C, Grau A (2004) A common polymorphism of the protein Z gene is associated with protein Z plasma levels and with risk of cerebral ischemia in the young. Stroke 35:40-45
8. Staton J, Sayer M, Hankey GJ, Cole V, Thom J, Eikelboom JW (2005) Protein Z gene polymorphisms, protein Z concentrations, and ischemic stroke. Stroke 36:1123-1127
9. Lichy C, Dong-Si T, Reuner K, Genius J, Rickmann H, Hampe T, Dolan T, Stoll F, Grau A (2006) Risk of cerebral venous thrombosis and novel gene polymorphisms of the coagulation and fibrinolytic systems. J Neurol 253:316-320
10. Eroglu A, Ulu A, Cam R, Kurtman C, Akar N (2007) Prevalence of factor V 1691 G-A (Leiden) and prothrombin G20210A polymorphisms and the risk of venous thrombosis among cancer patients. J Thromb Thrombolysis 23:31-34