p34sei-1 inhibits ros-induced cell death through suppression of ASK1

Cancer Biology and Therapy

Volumn 12, Issue 5, 2011, Pages 421-426

  Hong, Seung Woo ^a,b   Shin, Jae Sik ^a,b   Lee, Young Min ^d   Kim, Dong Gil ^c   Lee, Sok Young ^d   Yoon, Dok Hyun ^b   Jung, Seong Yun ^a   Hwang, Jung Jin ^a   Lee, Seung Jin ^a   Cho, Dong Hyung ^e   Hong, Yong Sang ^a,b   Kim, Tae Won ^a,b   Jin, Dong Hoon ^a,b   Lee, Won Keun ^c  

^a University of Ulsan College of Medicine   (South Korea)

^b Asan Medical Center   (South Korea)

^c Myong Ji University   (South Korea)

^d National Institute of Animal Science   (South Korea)

^e Kyung Hee University   (South Korea)

Author keywords

ASK1; p34SEI 1; ROS; Ubiquitination

Indexed keywords

APOPTOSIS SIGNAL REGULATING KINASE 1; CYCLIN DEPENDENT KINASE 1; HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE; INHIBITOR OF APOPTOSIS PROTEIN; MAP3K5 PROTEIN, HUMAN; NUCLEAR PROTEIN; SERTAD1 PROTEIN, HUMAN; SMALL INTERFERING RNA; TRANSACTIVATOR PROTEIN; UBIQUITIN;

ARTICLE; CELL DEATH; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; UBIQUITINATION; APOPTOSIS; CELL CYCLE; CELL LINE; COLON TUMOR; GENETICS; METABOLISM; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

APOPTOSIS; CELL CYCLE; CELL LINE; COLONIC NEOPLASMS; HUMANS; HYDROGEN PEROXIDE; INHIBITOR OF APOPTOSIS PROTEINS; MAP KINASE KINASE KINASE 5; NUCLEAR PROTEINS; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; UBIQUITIN; UBIQUITINATION;

EID: 80052379330     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.12.5.15972     Document Type: Article

References (24)

1. Nagai H., Noguchi T., Takeda K., Ichijo H. Pathophysiological roles of ASK1-MAP kinase signaling pathways. J Biochem Mol Biol 2007; 40:1-6; PMID: 17244475; DOI: 10.5483/BMBRep.2007.40.1.001.
2. Matsuzawa A., Nishitoh H., Tobiume K., Takeda K., Ichijo H. Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: advanced findings from ASK1 knockout mice. Antioxid Redox Signal 2002; 4:415-25; PMID: 12215209; DOI: 10.1089/ 15230860260196218.
3. Kyriakis J.M., Avruch J. Protein kinase cascades activated by stress and inflammatory cytokines. Bioessays 1996; 18:567-77; PMID: 8757935; DOI: 10.1002/ bies.950180708.
4. Matsuzawa A., Ichijo H. Stress-responsive protein kinases in redoxregulated apoptosis signaling. Antioxid Redox Signal 2005; 7:472-81; PMID: 15706095; DOI: 10.1089/ars.2005.7.472.
5. Giorgio M., Trinei M., Migliaccio E., Pelicci PG. Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals? Nat Rev Mol Cell Biol 2007; 8:722-8; PMID: 17700625; DOI: 10.1038/ nrm2240.
6. Matsuzawa A., Ichijo H. Redox control of cell fate by MAP kinase: physiological roles of ASK1-MAP kinase pathway in stress signaling. Biochim Biophysica Acta 2008; 1780:1325-36; PMID: 18206122.
7. Tobiume K., Saitoh M., Ichijo H. Activation of apoptosis signal-regulating kinase 1 by the stress-induced activating phosphorylation of pre-formed oligomer. J Cell Physiol 2002; 191:95-104; PMID: 11920685; DOI: 10.1002/jcp.10080.
8. Fujino G., Nogucji T., Matsuzawa A., Yamauchi S., Saitoh M., Takeda K., et al. Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1. Mol Cell Biol 2007; 27:8152-63; PMID: 17724081; DOI: 10.1128/MCB.00227-07.
9. Gao Y., Han C., Huang H., Xin Y., Xu Y., Luo L., et al. Heat shock protein 70 together with its co-chaperone CHIP inhibits TNFalpha induced apoptosis by promoting proteasomal degradation of apoptosis signalregulating kinase1. Apoptosis 2010; 15:822-33; PMID: 20349136; DOI: 10.1007/s10495-010- 0495-7.
10. Zhao Y., Conze D.B., Hanover J.A., Ashwell JD. Tumor necrosis factor receptor 2 signaling induces selective c-IAP1-dependent ASK1 ubiquitination and terminates mitogen-activated protein kinase signaling. J Biol Chem 2007; 282:7777-82; PMID: 17220297; DOI: 10.1074/jbc.M609146200.
11. Ballinger C.A., Connell P., Wu Y., Hu Z., Thompson L.J., Yin L.Y., et al. Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions. Mol Cell Biol 1999; 19:4535-4545; PMID: 10330192.
12. Hwang J.R., Zhang C., Patterson C. C-terminus of heat shock protein 70-interacting protein facilitates degradation of apoptosis signal-regulating kinase 1 and inhibits apoptosis signal-regulating kinase 1-dependent apoptosis. Cell Stress Chaperones 2005; 10:147-56; PMID: 16038411; DOI: 10.1379/CSC-90R.1.
13. Sugimoto M., Nakamura T., Hampson L., Hampson I.N., Shimamoto A., et al. Regulation of CDK4 activity by a novel CDK4-binding protein, p34(SEI-1). Genes Dev 1999; 13:3027-33; PMID: 10580009; DOI: 10.1101/gad.13.22.3027.
14. Hong S.W., Kim C.J., Park W.S., Shin J.S., Lee S.D., Ko S.G., et al. p34SEI-1 inhibits apoptosis through the stabilization of the X-linked inhibitor of apoptosis protein: p34SEI-1 as a novel target for anti-breast cancer strategies. Cancer Res 2009; 69:741-6; PMID: 19176394; DOI: 10.1158/0008-5472. CAN-08-1189.
15. Lee S.L.O., Hong S.W., Shin J.S., Kim J.S., Ko S.G., Hong N.J., et al. p34SEI-1 inhibits doxorubicin-induced senescence through a pathway mediated by protein kinase C-delta and c-Jun-NH2-kinase 1 activation in human breast cancer MCF7 cells. Mol Cancer Res 2009; 7:1845-53; PMID: 19903772; DOI: 10.1158/1541-7786.MCR-09-0086.
16. Subramanyam M., Takahashi N., Hasegawa Y., Mohri T., Okada Y. Inhibition of protein kinase Akt1 by Apoptosis Signal-regulating Kinase-1 (ASK1) is involved in apoptotic inhibition of regulatory volume increase. J Biol Chem 2010; 285:6109-17; PMID: 20048146; DOI: 10.1074/jbc.M109.072785.
17. Kuo P.L., Chen C.Y., Hsu YL. Isoobtusilactone A induces cell cycle arrest and apoptosis through reactive oxygen species/apoptosis signal-regulating kinase 1 signaling pathway in human breast cancer cells. Cancer Res 2007; 67:7406-20; PMID: 17671211; DOI: 10.1158/0008-5472.CAN-07-1089.
18. Shieh J.M., Huang T.F., Hung C.F., Chou K.H., Tsai Y.J., Wu WB. Activation of c-Jun N-terminal kinase is essential for mitochondrial membrane potential change and apoptosis induced by doxycycline in melanoma cells. Br J Pharmacol 2010; 160:1171-84; PMID: 20590610; DOI: 10.1111/j.1476-5381.2010. 00746.x.
19. Ouyang M., Shen X. Critical role of ASK1 in the 6-hydroxydopamine-induced apoptosis in human neuroblastoma SH-SY5Y cells. J Neurochem 2006; 97:234-44; PMID: 16515547; DOI: 10.1111/j.1471- 4159.2006.03730.x.
20. Kuo C.T., Chen B.C., Yu C.C., Weng C.M., Hsu M.J., Chen C.C., et al. Apoptosis signal-regulating kinase 1 mediates denbinobin-induced apoptosis in human lung adenocarcinoma cells. J Biomed Sci 2009; 16:43; PMID: 19405983; DOI: 10.1186/1423-0127-16-43.
21. Liu Y., Min W. Thioredoxin Promotes ASK1 ubiquitination and degradation to inhibit ASK1-mediated apoptosis in a redox activity-independent manner. Circ Res 2002; 90:1259-66; PMID: 12089063; DOI: 10.1161/01.RES.0000022160.64355.62.
22. Zhang Z., Hao J., Zhao Z., Ben P., Fang F., Shi L., et al. beta-Arrestins facilitate ubiquitin-dependent degradation of apoptosis signal-regulating kinase 1 (ASK1) and attenuate H2O2-induced apoptosis. Cell Signal 2009; 21:1195-206; PMID: 19306926; DOI: 10.1016/j. cellsig.2009.03.010.
23. Noh K.T., Cho S.G., Choi EJ. Knockdown of apoptosis signal-regulating kinase 1 modulates basal glycogen synthase kinase-3β kinase activity and regulates cell migration. FEBS Lett 2010; 584:4097-101; PMID: 20800594; DOI: 10.1016/j.febslet.2010.08.029.
24. Subramanyam M., Takahashi N., Hasegawa Y., Mohri T., Okada Y. Inhibition of protein kinase Akt1 by apoptosis signal-regulating kinase-1 (ASK1) is involved in apoptotic inhibition of regulatory volume increase. J Biol Chem 2010; 285:6109-17; PMID: 20048146; DOI: 10.1074/jbc.M109.072785.