Knockdown of apoptosis signal-regulating kinase 1 modulates basal glycogen synthase kinase-3β kinase activity and regulates cell migration

FEBS Letters

Volumn 584, Issue 18, 2010, Pages 4097-4101

  Noh, Kyung Tae ^a   Cho, Ssang Goo ^b   Choi, Eui Ju ^a  

^a Korea University   (South Korea)

^b Konkuk University   (South Korea)

Author keywords

Catenin; ASK1; Axin; GSK 3 ; Migration

Indexed keywords

APOPTOSIS SIGNAL REGULATING KINASE 1; AXIN; BETA CATENIN; GLYCOGEN SYNTHASE KINASE 3BETA; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; MAP3K5 PROTEIN, HUMAN;

ARTICLE; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CELL MIGRATION; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; ANTAGONISTS AND INHIBITORS; APOPTOSIS; BREAST TUMOR; CELL MOTION; ENZYMOLOGY; GENE SILENCING; GENETICS; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

APOPTOSIS; BETA CATENIN; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; GENE KNOCKDOWN TECHNIQUES; GLYCOGEN SYNTHASE KINASE 3; HUMANS; MAP KINASE KINASE KINASE 5;

EID: 77956937498     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2010.08.029     Document Type: Article

References (17)

1. Ichijo H., Nishida E., Irie K., ten Dijke P., Saitoh M., Moriguchi T., Takagi M., Matsumoto K., Miyazono K., Gotoh Y. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 1997, 275:90-94.
2. Hatai T., Matsuzawa A., Inoshita S., Mochida Y., Kuroda T., Sakamaki K., Kuida K., Yonehara S., Ichijo H., Takeda K. Execution of apoptosis signal-regulating kinase 1 (ASK1)-induced apoptosis by the mitochondria-dependent caspase activation. J. Biol. Chem. 2000, 275:26576-26581.
3. Matsuzawa A., Ichijo H. Redox control of cell fate by MAP kinase: physiological roles of ASK1-MAP kinase pathway in stress signaling. Biochim. Biophys. Acta 2008, 1780:1325-1336.
4. J.R. Woodgett, Judging a protein by more than its name: GSK-3, Sci. STKE (2001) re12.
5. Yamamoto H., Kishida S., Kishida M., Ikeda S., Takada S., Kikuchi A. Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability. J. Biol. Chem. 2009, 274:10681-10684.
6. Kikuchi A. Roles of Axin in the Wnt signalling pathway. Cell. Signal. 1999, 11:777-788.
7. Kishida M., Koyama S., Kishida S., Matsubara K., Nakashima S., Higano K., Takada R., Takada S., Kikuchi A. Axin prevents Wnt-3a-induced accumulation of beta-catenin. Oncogene 1999, 18:979-985.
8. Ikeda S., Kishida S., Yamamoto H., Murai H., Koyama S., Kikuchi A. Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin. EMBO J. 1998, 17:1371-1384.
9. Stambolic V., Ruel L., Woodgett J.R. Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells. Curr. Biol. 1996, 6:1664-1668.
10. Giles R.H., van Es J.H., Clevers H. Caught up in a Wnt storm: Wnt signaling in cancer. Biochim. Biophys. Acta 2003, 1653:1-24.
11. Moon R.T., Kohn A.D., De Ferrari G.V., Kaykas A. WNT and beta-catenin signalling: diseases and therapies. Nat. Rev. Genet. 2004, 5:691-701.
12. Kim E.K., Noh K.T., Yoon J.H., Cho J.H., Yoon K.W., Dreyfuss G., Choi E.J. Positive regulation of ASK1-mediated c-Jun NH(2)-terminal kinase signaling pathway by the WD-repeat protein Gemin5. Cell Death Differ. 2007, 14:1518-1528.
13. Willert K., Shibamoto S., Nusse R. Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex. Genes Dev. 1999, 13:1768-1773.
14. Ishibe S., Haydu J.E., Togawa A., Marlier A., Cantley L.G. Cell confluence regulates hepatocyte growth factor-stimulated cell morphogenesis in a beta-catenin-dependent manner. Mol. Cell. Biol. 2006, 26:9232-9243.
15. Qi J., Chen N., Wang J., Siu C.H. Transendothelial migration of melanoma cells involves N-cadherin-mediated adhesion and activation of the beta-catenin signaling pathway. Mol. Biol. Cell 2005, 16:4386-4397.
16. Zhou B.P., Deng J., Xia W., Xu J., Li Y.M., Gunduz M., Hung M.C. Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition. Nat. Cell Biol. 2004, 6:931-940.
17. Bachelder R.E., Yoon S.O., Franci C., de Herreros A.G., Mercurio A.M. Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription: implications for the epithelial-mesenchymal transition. J. Cell Biol. 2005, 168:29-33.