The simplest method for in vitro Β-cell production from human adult stem cells

Differentiation

Volumn 82, Issue 3, 2011, Pages 144-152

  Bhandari, Dilli Ram ^a   Seo, Kwang Won ^a   Sun, Bo ^a   Seo, Min Soo ^a   Kim, Hyung Sik ^a   Seo, Yoo Jin ^a   Marcin, Jurga ^b   Forraz, Nicolas ^b   Roy, Helene Le ^b   Larry, Denner ^c   Colin, McGuckin ^b   Kang, Kyung Sun ^a  

^a Seoul National University   (South Korea)

^b Cell Therapy Research Institute   (France)

^c University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Diabetes; Differentiation; Duration; Insulin; Protocol; Stem cells

Indexed keywords

BETA ACTIN; C PEPTIDE; CONNEXIN 36; GLUCAGON; GLUCOSE; INSULIN; NESTIN; NEUROGENIN 3; PEPTIDE YY; TRANSCRIPTION FACTOR NKX6.1; TRANSCRIPTION FACTOR PDX 1; TRANSCRIPTION FACTOR SOX17;

ADULT STEM CELL; AMNIOTIC EPITHELIAL STEM CELL; ARTICLE; CELL DIFFERENTIATION; CONNEXIN 36 GENE; CONTROLLED STUDY; CULTURE MEDIUM; ENDODERM; ENZYME LINKED IMMUNOSORBENT ASSAY; GCG GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INS GENE; MARKER GENE; MESENCHYMAL STEM CELL; NGN3 GENE; NKX6.1 GENE; PANCREAS; PANCREAS ISLET BETA CELL; PANCREATIC ENDODERM; PANCREATIC FOREGUT; PDX1 GENE; PPY GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOX17 GENE; STEM CELL; UMBILICAL CORD BLOOD DERIVED MESENCHYMAL STEM CELL; WHARTON JELLY DERIVED MESENCHYMAL STEM CELL;

ADULT; ADULT STEM CELLS; BIOLOGICAL MARKERS; C-PEPTIDE; CELL DIFFERENTIATION; GLUCOSE; HUMANS; INSULIN; INSULIN-SECRETING CELLS; MESENCHYMAL STROMAL CELLS; WHARTON JELLY;

EID: 80052378655     PISSN: 03014681     EISSN: 14320436     Source Type: Journal    
DOI: 10.1016/j.diff.2011.06.003     Document Type: Article

References (36)

1. Beischer W., Heinze E., Keller L., Raptis S., Kerner W., Pfeiffer E.F. Human C-peptide, Part II: clinical studies. Klin. Wochenschr. 1976, 54:717-725.
2. Bhandari D.R., Seo K.W., Jung J.W., Kim H.S., Yang S.R., Kang K.S. The regulatory role of c-MYC on HDAC2 and PcG expression in human multipotent stem cells. J. Cell. Mol. Med. 2011, 15:1603-1614.
3. Bhandari D.R., Seo K.W., Roh K.H., Jung J.W., Kang S.K., Kang K.S. REX-1 expression and p38 MAPK activation status can determine proliferation/differentiation fates in human mesenchymal stem cells. PLoS One 2011, 5:e10493.
4. Bristow A.F., Das R.E. WHO international reference reagents for human proinsulin and human insulin C-peptide. J. Biol. Standards 1988, 16:179-186.
5. Copeland N., Harris D., Gaballa M.A. Human umbilical cord blood stem cells, myocardial infarction and stroke. Clin. Med. 2009, 9:342-345.
6. D'Amour K.A., Bang A.G., Eliazer S., Kelly O.G., Agulnick A.D., Smart N.G., Moorman M.A., Kroon E., Carpenter M.K., Baetge E.E. Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat. Biotechnol. 2006, 24:1392-1401.
7. Gao F., Wu D.Q., Hu Y.H., Jin G.X. Extracellular matrix gel is necessary for in vitro cultivation of insulin producing cells from human umbilical cord blood derived mesenchymal stem cells. Chin. Med. J. (Engl.) 2008, 121:811-818.
8. Gjessing H.J., Matzen L.E., Faber O.K., Froland A. Sensitivity and reproducibility of urinary C-peptide as estimate of islet B-cell function in insulin-treated diabetes. Diabet. Med. 1989, 6:329-333.
9. Goicoa S., Alvarez S., Ricordi C., Inverardi L., Dominguez-Bendala J. Sodium butyrate activates genes of early pancreatic development in embryonic stem cells. Cloning Stem Cells 2006, 8:140-149.
10. Jiang J., Au M., Lu K., Eshpeter A., Korbutt G., Fisk G., Majumdar A.S. Generation of insulin-producing islet-like clusters from human embryonic stem cells. Stem Cells 2007, 25:1940-1953.
11. Jiang W., Shi Y., Zhao D., Chen S., Yong J., Zhang J., Qing T., Sun X., Zhang P., Ding M., Li D., Deng H. In vitro derivation of functional insulin-producing cells from human embryonic stem cells. Cell Res. 2007, 17:333-344.
12. Kang K.S., Kim S.W., Oh Y.H., Yu J.W., Kim K.Y., Park H.K., Song C.H., Han H. A 37-year-old spinal cord-injured female patient, transplanted of multipotent stem cells from human UC blood, with improved sensory perception and mobility, both functionally and morphologically: a case study. Cytotherapy 2005, 7:368-373.
13. Le Gurun S., Martin D., Formenton A., Maechler P., Caille D., Waeber G., Meda P., Haefliger J.A. Connexin-36 contributes to control function of insulin-producing cells. J. Biol. Chem. 2003, 278:37690-37697.
14. Lumelsky N., Blondel O., Laeng P., Velasco I., Ravin R., McKay R. Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets. Science 2001, 292:1389-1394.
15. Magatti M., De Munari S., Vertua E., Gibelli L., Wengler G.S., Parolini O. Human amnion mesenchyme harbors cells with allogeneic T-cell suppression and stimulation capabilities. Stem Cells 2008, 26:182-192.
16. Mfopou J.K., Chen B., Sui L., Sermon K., Bouwens L. Recent advances and prospects in the differentiation of pancreatic cells from human embryonic stem cells. Diabetes 2011, 59:2094-2101.
17. Moodley Y., Ilancheran S., Samuel C., Vaghjiani V., Atienza D., Williams E.D., Jenkin G., Wallace E., Trounson A., Manuelpillai U. Human amnion epithelial cell transplantation abrogates lung fibrosis and augments repair. Am. J. Respir. Crit. Care Med. 2011, 182:643-651.
18. Movassat J., Beattie G.M., Lopez A.D., Portha B., Hayek A. Keratinocyte growth factor and beta-cell differentiation in human fetal pancreatic endocrine precursor cells. Diabetologia 2003, 46:822-829.
19. Murphy S., Rosli S., Acharya R., Mathias L., Lim R., Wallace E., Jenkin G. Amnion epithelial cell isolation and characterization for clinical use. Curr. Protocol Stem Cell Biol. 2011, 1E(6):1-25. (Chapter 1).
20. Murtaugh L.C. Pancreas and beta-cell development: from the actual to the possible. Development 2007, 134:427-438.
21. Seo K.W., Lee S.R., Bhandari D.R., Roh K.H., Park S.B., So A.Y., Jung J.W., Seo M.S., Kang S.K., Lee Y.S., Kang K.S. OCT4A contributes to the stemness and multi-potency of human umbilical cord blood-derived multipotent stem cells (hUCB-MSCs). Biochem. Biophys. Res. Commun. 2009, 384:120-125.
22. Seo, Y., Yang, S.R., Jee, M.K., Joo, E.K., Roh, K.H., Seo, M.S., Han, T.H., Lee, S.Y., Ryu, P.D., Jung, J.W., Seo, K.W., Kang, S.K., and Kang, K.S. Human umbilical cord blood-derived mesenchymal stem cells protect against neuronal cell death and ameliorate motor Deficits in Niemann pick type C1 mice. Cell Transplant., in press. http://doi:0.3727/096368910X545086.
23. Serre-Beinier V., Bosco D., Zulianello L., Charollais A., Caille D., Charpantier E., Gauthier B.R., Diaferia G.R., Giepmans B.N., Lupi R., Marchetti P., Deng S., Buhler L., Berney T., Cirulli V., Meda P. Cx36 makes channels coupling human pancreatic beta-cells, and correlates with insulin expression. Hum. Mol. Genet. 2009, 18:428-439.
24. Serup P., Madsen O.D., Mandrup-Poulsen T. Islet and stem cell transplantation for treating diabetes. Br. Med. J. 2001, 322:29-32.
25. Shi Y., Hou L., Tang F., Jiang W., Wang P., Ding M., Deng H. Inducing embryonic stem cells to differentiate into pancreatic beta cells by a novel three-step approach with activin A and all-trans retinoic acid. Stem Cells 2005, 23:656-662.
26. Soria B. In-vitro differentiation of pancreatic beta-cells. Differentiation 2001, 68:205-219.
27. Sulzbacher S., Schroeder I.S., Truong T.T., Wobus A.M. Activin A-induced differentiation of embryonic stem cells into endoderm and pancreatic progenitors-the influence of differentiation factors and culture conditions. Stem Cell Rev. 2009, 5:159-173.
28. Tai M.H., Olson L.K., Madhukar B.V., Linning K.D., Van Camp L., Tsao M.S., Trosko J.E. Characterization of gap junctional intercellular communication in immortalized human pancreatic ductal epithelial cells with stem cell characteristics. Pancreas 2003, 26:e18-26.
29. Treutelaar M.K., Skidmore J.M., Dias-Leme C.L., Hara M., Zhang L., Simeone D., Martin D.M., Burant C.F. Nestin-lineage cells contribute to the microvasculature but not endocrine cells of the islet. Diabetes 2003, 52:2503-2512.
30. Uzan B., Figeac F., Portha B., Movassat J. Mechanisms of KGF mediated signaling in pancreatic duct cell proliferation and differentiation. PLoS One 2009, 4:e4734.
31. Wahren J., Ekberg K., Johansson J., Henriksson M., Pramanik A., Johansson B.L., Rigler R., Jornvall H. Role of C-peptide in human physiology. Am. J. Physiol. Endocrinol. Metab. 2000, 278:E759-768.
32. Wang H.S., Hung S.C., Peng S.T., Huang C.C., Wei H.M., Guo Y.J., Fu Y.S., Lai M.C., Chen C.C. Mesenchymal stem cells in the Wharton's jelly of the human umbilical cord. Stem Cells 2004, 22:1330-1337.
33. Wang H.S., Shyu J.F., Shen W.S., Hsu H.C., Chi T.C., Chen C.P., Huang S.W., Shyr Y.M., Tang K.T., Chen T.H. Transplantation of insulin producing cells derived from umbilical cord stromal mesenchymal stem cells to treat NOD mice. Cell Transplant 2011, 20:455-466.
34. Wei J.P., Zhang T.S., Kawa S., Aizawa T., Ota M., Akaike T., Kato K., Konishi I., Nikaido T. Human amnion-isolated cells normalize blood glucose in streptozotocin-induced diabetic mice. Cell Transplant. 2003, 12:545-552.
35. Ye F., Duvillie B., Scharfmann R. Fibroblast growth factors 7 and 10 are expressed in the human embryonic pancreatic mesenchyme and promote the proliferation of embryonic pancreatic epithelial cells. Diabetologia 2005, 48:277-281.
36. Zhao Y., Mazzone T. Human cord blood stem cells and the journey to a cure for type 1 diabetes. Autoimmun. Rev. 2011, 10:103-107.