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Volumn 18, Issue 3, 2009, Pages 428-439

Cx36 makes channels coupling human pancreatic β-cells, and correlates with insulin expression

Author keywords

[No Author keywords available]

Indexed keywords

CONNEXIN 36; INSULIN; MESSENGER RNA;

EID: 58749115233     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddn370     Document Type: Article
Times cited : (97)

References (76)
  • 1
    • 17344390158 scopus 로고    scopus 로고
    • Plasma membrane channels formed by connexins: Their regulation and functions
    • Saez, J.C., Berthoud, V.M., Branes, M.C., Martinez, A.D. and Beyer, E.C. (2003) Plasma membrane channels formed by connexins: Their regulation and functions. Physiol. Rev., 83, 1359-1400.
    • (2003) Physiol. Rev , vol.83 , pp. 1359-1400
    • Saez, J.C.1    Berthoud, V.M.2    Branes, M.C.3    Martinez, A.D.4    Beyer, E.C.5
  • 2
    • 1942438964 scopus 로고    scopus 로고
    • Gap junctions and the connexin protein family
    • Söhl, G. and Willecke, K. (2004) Gap junctions and the connexin protein family. Cardiovasc. Res., 62, 228-232.
    • (2004) Cardiovasc. Res , vol.62 , pp. 228-232
    • Söhl, G.1    Willecke, K.2
  • 6
    • 0024430064 scopus 로고
    • Homologous but not heterologous contact increases the insulin secretion of individual pancreatic B-cells
    • Bosco, D., Orci, L. and Meda, P. (1989) Homologous but not heterologous contact increases the insulin secretion of individual pancreatic B-cells. Exp. Cell Res., 184, 72-80.
    • (1989) Exp. Cell Res , vol.184 , pp. 72-80
    • Bosco, D.1    Orci, L.2    Meda, P.3
  • 7
    • 0025149615 scopus 로고
    • Rapid and reversible secretion changes during uncoupling of rat insulin-producing cells
    • Meda, P., Bosco, D., Chanson, M., Giordano, E., Vallar, L., Wollheim, C. and Orci, L. (1990) Rapid and reversible secretion changes during uncoupling of rat insulin-producing cells. J. Clin. Invest., 86 759-768.
    • (1990) J. Clin. Invest , vol.86 , pp. 759-768
    • Meda, P.1    Bosco, D.2    Chanson, M.3    Giordano, E.4    Vallar, L.5    Wollheim, C.6    Orci, L.7
  • 8
    • 0037315584 scopus 로고    scopus 로고
    • Connexin 36 controls synchronization of Ca2+ oscillations and insulin secretion in MIN6 cells
    • Calabrese, A., Zhang, M., Serre-Beinier, V., Caton, D., Mas, C., Satin, L.S. and Meda, P. (2003) Connexin 36 controls synchronization of Ca2+ oscillations and insulin secretion in MIN6 cells. Diabetes, 52 417-424.
    • (2003) Diabetes , vol.52 , pp. 417-424
    • Calabrese, A.1    Zhang, M.2    Serre-Beinier, V.3    Caton, D.4    Mas, C.5    Satin, L.S.6    Meda, P.7
  • 9
    • 0038010435 scopus 로고    scopus 로고
    • Lentivirus-mediated transduction of connexin cDNAs shows level- and isoform-specific alterations in insulin secretion of primary pancreatic beta-cells
    • Caton, D., Calabrese, A., Mas, C., Serre-Beinier, V., Charollais, A., Caille, D., Zufferey, R., Trono, D. and Meda, P. (2003) Lentivirus-mediated transduction of connexin cDNAs shows level- and isoform-specific alterations in insulin secretion of primary pancreatic beta-cells. J. Cell Sci., 116, 2285-2294.
    • (2003) J. Cell Sci , vol.116 , pp. 2285-2294
    • Caton, D.1    Calabrese, A.2    Mas, C.3    Serre-Beinier, V.4    Charollais, A.5    Caille, D.6    Zufferey, R.7    Trono, D.8    Meda, P.9
  • 10
    • 0022572975 scopus 로고
    • Heterogeneity and contact-dependent regulation of hormone secretion by individual B cells
    • Salomon, D. and Meda, P. (1988) Heterogeneity and contact-dependent regulation of hormone secretion by individual B cells. Exp. Cell Res. 162, 507-520.
    • (1988) Exp. Cell Res , vol.162 , pp. 507-520
    • Salomon, D.1    Meda, P.2
  • 11
    • 0001245306 scopus 로고    scopus 로고
    • Reconstructing islet function in vitro
    • Bosco, D. and Meda, P. (1997) Reconstructing islet function in vitro. Adv. Exp. Med. Biol., 426, 285-298.
    • (1997) Adv. Exp. Med. Biol , vol.426 , pp. 285-298
    • Bosco, D.1    Meda, P.2
  • 12
    • 0025718832 scopus 로고
    • Actively synthesizing beta-cells secrete preferentially after glucose stimulation
    • Bosco, D. and Meda, P. (1991) Actively synthesizing beta-cells secrete preferentially after glucose stimulation. Endocrinology, 129 3157-3166.
    • (1991) Endocrinology , vol.129 , pp. 3157-3166
    • Bosco, D.1    Meda, P.2
  • 13
    • 20044389102 scopus 로고    scopus 로고
    • Loss of connexin36 channels alters beta-cell coupling, islet synchronization of glucose-induced Ca2+ and insulin oscillations, and basal insulin release
    • Ravier, M.A., Güldenagel, M., Charollais, A., Gjinovci, A., Caille, D., Söhl, G., Wollheim, C.B., Willecke, K., Henquin, J.C. and Meda, P. (2005) Loss of connexin36 channels alters beta-cell coupling, islet synchronization of glucose-induced Ca2+ and insulin oscillations, and basal insulin release. Diabetes, 54, 1798-1807.
    • (2005) Diabetes , vol.54 , pp. 1798-1807
    • Ravier, M.A.1    Güldenagel, M.2    Charollais, A.3    Gjinovci, A.4    Caille, D.5    Söhl, G.6    Wollheim, C.B.7    Willecke, K.8    Henquin, J.C.9    Meda, P.10
  • 14
    • 39549098881 scopus 로고    scopus 로고
    • A conditional mouse mutant with cyan fluorescent reporter protein reveals specific expression and functions of Connexin36 in neurons of the central nervous system and pancreatic beta-cells
    • Wellershaus, K., Degen, J., Deuchars, J., Theis, M., Charollais, A., Caille, D., Gauthier, B., Janssen-Bienhold, U., Meda, P. and Willecke, K. (2008) A conditional mouse mutant with cyan fluorescent reporter protein reveals specific expression and functions of Connexin36 in neurons of the central nervous system and pancreatic beta-cells. Exp. Cell Res., 314, 997-1012.
    • (2008) Exp. Cell Res , vol.314 , pp. 997-1012
    • Wellershaus, K.1    Degen, J.2    Deuchars, J.3    Theis, M.4    Charollais, A.5    Caille, D.6    Gauthier, B.7    Janssen-Bienhold, U.8    Meda, P.9    Willecke, K.10
  • 15
    • 34047149839 scopus 로고    scopus 로고
    • Cx36-mediated coupling reduces beta-cell heterogeneity, confines the stimulating glucose concentration range, and affects insulin release kinetics
    • Speier, S., Gjinovci, A., Charollais, A., Meda, P. and Rupnik, M. (2007) Cx36-mediated coupling reduces beta-cell heterogeneity, confines the stimulating glucose concentration range, and affects insulin release kinetics. Diabetes, 56, 1078-1086.
    • (2007) Diabetes , vol.56 , pp. 1078-1086
    • Speier, S.1    Gjinovci, A.2    Charollais, A.3    Meda, P.4    Rupnik, M.5
  • 16
    • 0023226183 scopus 로고
    • Pulsatility of insulin and glucagon release: Physiological significance and pharmacological implications
    • Lefebvre, P.J., Paolisso, G., Scheen, A.J. and Henquin, J.C. (1987) Pulsatility of insulin and glucagon release: Physiological significance and pharmacological implications. Diabetologia, 30, 443-452.
    • (1987) Diabetologia , vol.30 , pp. 443-452
    • Lefebvre, P.J.1    Paolisso, G.2    Scheen, A.J.3    Henquin, J.C.4
  • 17
    • 0019415621 scopus 로고
    • Brief, irregular oscillations of basal plasma insulin and glucose concentrations in diabetic man
    • Lang, D.A., Matthews, D.R., Burnett, M.A. and Turner, R.C. (1981) Brief, irregular oscillations of basal plasma insulin and glucose concentrations in diabetic man. Diabetes, 30, 435-439.
    • (1981) Diabetes , vol.30 , pp. 435-439
    • Lang, D.A.1    Matthews, D.R.2    Burnett, M.A.3    Turner, R.C.4
  • 18
    • 0023951171 scopus 로고    scopus 로고
    • Impaired pulsatile secretion of insulin in relatives of patients with non-insulin-dependent diabetes
    • O'Rahilly, S., Turner, R.C. and Matthews, D.R. Impaired pulsatile secretion of insulin in relatives of patients with non-insulin-dependent diabetes. N. Engl. J. Med., 318, 1225-1230.
    • N. Engl. J. Med , vol.318 , pp. 1225-1230
    • O'Rahilly, S.1    Turner, R.C.2    Matthews, D.R.3
  • 19
    • 0034235095 scopus 로고    scopus 로고
    • Assessment of insulin secretion in relatives of patients with type 2 (non-insulin-dependent) diabetes mellitus: Evidence of early beta-cell dysfunction
    • Nyholm, B., Pørksen, N., Juhl, C.B., Gravholt, C.H., Butler, P.C., Weeke, J., Veldhuis, J.D., Pincus, S. and Schmitz, O. (2000) Assessment of insulin secretion in relatives of patients with type 2 (non-insulin-dependent) diabetes mellitus: Evidence of early beta-cell dysfunction. Metabolism, 49, 896-905.
    • (2000) Metabolism , vol.49 , pp. 896-905
    • Nyholm, B.1    Pørksen, N.2    Juhl, C.B.3    Gravholt, C.H.4    Butler, P.C.5    Weeke, J.6    Veldhuis, J.D.7    Pincus, S.8    Schmitz, O.9
  • 23
  • 24
    • 48249083049 scopus 로고    scopus 로고
    • Voltage-gated ion channels in human pancreatic β-cells: Electrophysiological characterization and role in insulin secretion
    • Braun, M., Ramracheya, R., Bengtsson, M., Zhang, Q., Karanauskaite, J., Partidge, C., Johnson, P.R. and Rorsman, P. (2008) Voltage-gated ion channels in human pancreatic β-cells: Electrophysiological characterization and role in insulin secretion. Diabetes, 57 1618-1628.
    • (2008) Diabetes , vol.57 , pp. 1618-1628
    • Braun, M.1    Ramracheya, R.2    Bengtsson, M.3    Zhang, Q.4    Karanauskaite, J.5    Partidge, C.6    Johnson, P.R.7    Rorsman, P.8
  • 25
  • 27
    • 0032101281 scopus 로고    scopus 로고
    • Enhanced secretion of amylase from exocrine pancreas of connexin32-deficient mice
    • Chanson, M., Fanjul, M., Bosco, D., Nelles, E., Suter, S., Willecke, K. and Meda, P. (1998) Enhanced secretion of amylase from exocrine pancreas of connexin32-deficient mice. J. Cell Biol., 141, 1267-1275.
    • (1998) J. Cell Biol , vol.141 , pp. 1267-1275
    • Chanson, M.1    Fanjul, M.2    Bosco, D.3    Nelles, E.4    Suter, S.5    Willecke, K.6    Meda, P.7
  • 28
    • 0033045837 scopus 로고    scopus 로고
    • Loss of alpha 1 connexin does not alter the prenatal differentiation of pancreatic beta cells and leads to the identification of another islet cell connexin
    • Charollais, A., Serre, V., Mock, C., Cogne, F., Bosco, D. and Meda, P. (1999) Loss of alpha 1 connexin does not alter the prenatal differentiation of pancreatic beta cells and leads to the identification of another islet cell connexin. Dev. Genet., 24, 13-26.
    • (1999) Dev. Genet , vol.24 , pp. 13-26
    • Charollais, A.1    Serre, V.2    Mock, C.3    Cogne, F.4    Bosco, D.5    Meda, P.6
  • 29
    • 0023680541 scopus 로고
    • The gap junction: A channel for multiple functions?
    • Bruzzone, R. and Meda, P. (1988) The gap junction: A channel for multiple functions? Eur. J. Clin. Invest., 18, 444-453.
    • (1988) Eur. J. Clin. Invest , vol.18 , pp. 444-453
    • Bruzzone, R.1    Meda, P.2
  • 30
    • 13644255296 scopus 로고    scopus 로고
    • Expression of connexin26 in islets of Langerhans is associated with impaired glucose tolerance in patients with pancreatic adenocarcinoma
    • Pfeffer, F., Koczan, D., Adam, U., Benz, S., von Dobschuetz, E., Prall, F., Nizze, H., Thiesen, H.J., Hopt, U.T. and Löbler, M. (2004) Expression of connexin26 in islets of Langerhans is associated with impaired glucose tolerance in patients with pancreatic adenocarcinoma. Pancreas, 29, 284-290.
    • (2004) Pancreas , vol.29 , pp. 284-290
    • Pfeffer, F.1    Koczan, D.2    Adam, U.3    Benz, S.4    von Dobschuetz, E.5    Prall, F.6    Nizze, H.7    Thiesen, H.J.8    Hopt, U.T.9    Löbler, M.10
  • 31
    • 0037035519 scopus 로고    scopus 로고
    • Connexin family members target to lipid raft domains and interact with caveolin-1
    • Schubert, A.L., Schubert, W., Spray, D.C. and Lisanti, M.P. (2002) Connexin family members target to lipid raft domains and interact with caveolin-1. Biochemistry, 41, 5754-5764.
    • (2002) Biochemistry , vol.41 , pp. 5754-5764
    • Schubert, A.L.1    Schubert, W.2    Spray, D.C.3    Lisanti, M.P.4
  • 32
    • 41649104490 scopus 로고    scopus 로고
    • Caveolin-1 and -2 interact with connexin43 and regulate gap junctional intercellular communication in keratinocytes
    • Langlois, S., Cowan, K.N., Shao, Q., Cowan, B.J. and Laird, D.W. (2007) Caveolin-1 and -2 interact with connexin43 and regulate gap junctional intercellular communication in keratinocytes. Mol. Biol. Cell., 19, 912-918.
    • (2007) Mol. Biol. Cell , vol.19 , pp. 912-918
    • Langlois, S.1    Cowan, K.N.2    Shao, Q.3    Cowan, B.J.4    Laird, D.W.5
  • 35
    • 33745831899 scopus 로고    scopus 로고
    • Caveolin-1 functions as a novel Cdc42 guanine nucleotide dissociation inhibitor in pancreatic beta-cells
    • Nevins, A.K. and Thurmond, D.C. (2006) Caveolin-1 functions as a novel Cdc42 guanine nucleotide dissociation inhibitor in pancreatic beta-cells. J. Biol. Chem., 281, 18961-18972.
    • (2006) J. Biol. Chem , vol.281 , pp. 18961-18972
    • Nevins, A.K.1    Thurmond, D.C.2
  • 36
    • 12944263962 scopus 로고    scopus 로고
    • Association of connexin36 with zonula occludens-1 in HeLa cells, betaTC-3 cells, pancreas, and adrenal gland
    • Li, X., Olson, C., Lu, S. and Nagy, J. (2004) Association of connexin36 with zonula occludens-1 in HeLa cells, betaTC-3 cells, pancreas, and adrenal gland. Histochem. Cell. Biol., 122, 485-498.
    • (2004) Histochem. Cell. Biol , vol.122 , pp. 485-498
    • Li, X.1    Olson, C.2    Lu, S.3    Nagy, J.4
  • 37
    • 2342567031 scopus 로고    scopus 로고
    • Neuronal connexin36 association with zonula occludens-1 protein (ZO-1) in mouse brain and interaction with the first PDZ domain of ZO-1
    • Li, X., Olson, C., Lu, S., Kamasawa, N., Yasumura, T., Rash, J.E. and Nagy, J.I. (2004) Neuronal connexin36 association with zonula occludens-1 protein (ZO-1) in mouse brain and interaction with the first PDZ domain of ZO-1. Eur. J. Neurosci., 19, 2132-2146.
    • (2004) Eur. J. Neurosci , vol.19 , pp. 2132-2146
    • Li, X.1    Olson, C.2    Lu, S.3    Kamasawa, N.4    Yasumura, T.5    Rash, J.E.6    Nagy, J.I.7
  • 38
    • 20444377656 scopus 로고    scopus 로고
    • Connexins and their environment: Effects of lipids composition on ion channels
    • Cascio, M. (2005) Connexins and their environment: Effects of lipids composition on ion channels. Biochim. Biophys. Acta, 1711, 142-153.
    • (2005) Biochim. Biophys. Acta , vol.1711 , pp. 142-153
    • Cascio, M.1
  • 39
    • 0024557352 scopus 로고
    • Effects of n alcohols on junctional coupling and amylase secretion of pancreatic acinar cells
    • Chanson, M., Bruzzone, R., Bosco, D. and Meda, P. (1989) Effects of n alcohols on junctional coupling and amylase secretion of pancreatic acinar cells. J. Cell. Physiol., 139, 147-156.
    • (1989) J. Cell. Physiol , vol.139 , pp. 147-156
    • Chanson, M.1    Bruzzone, R.2    Bosco, D.3    Meda, P.4
  • 41
    • 34848866666 scopus 로고    scopus 로고
    • Beta cells preferentially exchange cationic molecules via connexin 36 gap junction channels
    • Charpantier, E., Cancela, J. and Meda, P. (2007) Beta cells preferentially exchange cationic molecules via connexin 36 gap junction channels. Diabetologia, 50, 2332-2341.
    • (2007) Diabetologia , vol.50 , pp. 2332-2341
    • Charpantier, E.1    Cancela, J.2    Meda, P.3
  • 42
    • 0035704411 scopus 로고    scopus 로고
    • Emerging issues of connexin channels: Biophysics fills the gap
    • Harris, A.L. (2001) Emerging issues of connexin channels: Biophysics fills the gap. Q Rev. Biophys., 34, 325-472.
    • (2001) Q Rev. Biophys , vol.34 , pp. 325-472
    • Harris, A.L.1
  • 44
    • 0026059963 scopus 로고
    • Biophysical properties of gap junctions between freshly dispersed pairs of mouse pancreatic beta cells
    • Pérez-Armendariz, M., Roy, C., Spray, D.C. and Bennett, M.V. (1991) Biophysical properties of gap junctions between freshly dispersed pairs of mouse pancreatic beta cells. Biophys. J., 59, 76-92.
    • (1991) Biophys. J , vol.59 , pp. 76-92
    • Pérez-Armendariz, M.1    Roy, C.2    Spray, D.C.3    Bennett, M.V.4
  • 45
    • 0029101240 scopus 로고
    • Magnitude and modulation of pancreatic beta-cell gap junction electrical conductance in situ
    • Mears, D., Sheppard, N.F. Jr., Atwater, I. and Rojas, E. (1995) Magnitude and modulation of pancreatic beta-cell gap junction electrical conductance in situ. J. Membr. Biol., 146, 163-176.
    • (1995) J. Membr. Biol , vol.146 , pp. 163-176
    • Mears, D.1    Sheppard Jr., N.F.2    Atwater, I.3    Rojas, E.4
  • 47
    • 0017123493 scopus 로고
    • Electrophysiological evidence for coupling between beta cells of pancreatic islets
    • Meissner, H.P. (1976) Electrophysiological evidence for coupling between beta cells of pancreatic islets. Nature, 262, 502-504.
    • (1976) Nature , vol.262 , pp. 502-504
    • Meissner, H.P.1
  • 48
    • 0037403708 scopus 로고    scopus 로고
    • On-line analysis of gap junctions reveals more efficient electrical than dye coupling between islet cells
    • Quesada, I., Fuentes, E., Andreu, E., Meda, P., Nadal, A. and Soria, B. (2003) On-line analysis of gap junctions reveals more efficient electrical than dye coupling between islet cells. Am. J. Physiol. Endocrinol. Metab., 284, E980-E987.
    • (2003) Am. J. Physiol. Endocrinol. Metab , vol.284
    • Quesada, I.1    Fuentes, E.2    Andreu, E.3    Meda, P.4    Nadal, A.5    Soria, B.6
  • 49
    • 0029588550 scopus 로고
    • Adequate connexin-mediated coupling is required for proper insulin production
    • Vozzi, C., Ullrich, S., Charollais, A., Philippe, J., Orci, L. and Meda, P. (1995) Adequate connexin-mediated coupling is required for proper insulin production. J. Cell Biol., 131, 1561-1572.
    • (1995) J. Cell Biol , vol.131 , pp. 1561-1572
    • Vozzi, C.1    Ullrich, S.2    Charollais, A.3    Philippe, J.4    Orci, L.5    Meda, P.6
  • 51
    • 0037064004 scopus 로고    scopus 로고
    • Molecular cloning, functional expression, and tissue distribution of a novel human gap junction-forming protein, connexin-31.9. Interaction with zona occludens protein-1
    • Nielsen, P.A., Beahm, D.L., Giepmans, B.N., Baruch, A., Hall, J.E. and Kumar, N.M. (2002) Molecular cloning, functional expression, and tissue distribution of a novel human gap junction-forming protein, connexin-31.9. Interaction with zona occludens protein-1. J. Biol. Chem., 277, 38272-38283.
    • (2002) J. Biol. Chem , vol.277 , pp. 38272-38283
    • Nielsen, P.A.1    Beahm, D.L.2    Giepmans, B.N.3    Baruch, A.4    Hall, J.E.5    Kumar, N.M.6
  • 52
    • 1942470625 scopus 로고    scopus 로고
    • Contribution of connexins to the function of the vascular wall
    • Haefliger, J.A., Nicod, P. and Meda, P. (2004) Contribution of connexins to the function of the vascular wall. Cardiovasc. Res., 62, 345-356.
    • (2004) Cardiovasc. Res , vol.62 , pp. 345-356
    • Haefliger, J.A.1    Nicod, P.2    Meda, P.3
  • 53
    • 38449116948 scopus 로고    scopus 로고
    • Transplantation: Current developments and future directions; the future of clinical islet transplantation as a cure for diabetes
    • Hogan, A., Pileggi, A. and Ricordi, C. (2008) Transplantation: Current developments and future directions; the future of clinical islet transplantation as a cure for diabetes. Front. Biosci., 13, 1192-1205.
    • (2008) Front. Biosci , vol.13 , pp. 1192-1205
    • Hogan, A.1    Pileggi, A.2    Ricordi, C.3
  • 54
    • 34249066108 scopus 로고    scopus 로고
    • Connexin-dependent transcellular transcriptomic networks in mouse brain
    • Iacobas, D.A., Iacobas, S. and Spray, D.C. (2007) Connexin-dependent transcellular transcriptomic networks in mouse brain. Prog. Biophys. Mol. Biol., 94, 169-185.
    • (2007) Prog. Biophys. Mol. Biol , vol.94 , pp. 169-185
    • Iacobas, D.A.1    Iacobas, S.2    Spray, D.C.3
  • 57
    • 0032928542 scopus 로고    scopus 로고
    • Loci on chromosomes 2 (NIDDM1) and 15 interact to increase susceptibility to diabetes in Mexican Americans
    • Cox, N.J., Frigge, M., Nicolae, D.L., Concannon, P., Hanis, C.L., Bell, G.I. and Kong, A. (1999) Loci on chromosomes 2 (NIDDM1) and 15 interact to increase susceptibility to diabetes in Mexican Americans. Nat. Genet., 21, 213-215.
    • (1999) Nat. Genet , vol.21 , pp. 213-215
    • Cox, N.J.1    Frigge, M.2    Nicolae, D.L.3    Concannon, P.4    Hanis, C.L.5    Bell, G.I.6    Kong, A.7
  • 58
    • 0036230486 scopus 로고    scopus 로고
    • Genome-wide search for type 2 diabetes in Japanese affected sib-pairs confirms susceptibility genes on 3q, 15q, and 20q and identifies two new candidate Loci on 7p and 11p
    • Mori, Y., Otabe, S., Dina, C., Yasuda, K., Populaire, C., Lecoeur, C., Vatin, V., Durand, E., Hara, K., Okada, T. et al. (2002) Genome-wide search for type 2 diabetes in Japanese affected sib-pairs confirms susceptibility genes on 3q, 15q, and 20q and identifies two new candidate Loci on 7p and 11p. Diabetes, 51, 1247-1255.
    • (2002) Diabetes , vol.51 , pp. 1247-1255
    • Mori, Y.1    Otabe, S.2    Dina, C.3    Yasuda, K.4    Populaire, C.5    Lecoeur, C.6    Vatin, V.7    Durand, E.8    Hara, K.9    Okada, T.10
  • 59
    • 1442349990 scopus 로고    scopus 로고
    • A genome-wide scan for childhood obesity-associated traits in French families shows significant linkage on chromosome 6q22.31-q23.2
    • Meyre, D., Lecoeur, C., Delplanque, J., Francke, S., Vatin, V., Durand, E., Weill, J., Dina, C. and Froguel, P. (2004) A genome-wide scan for childhood obesity-associated traits in French families shows significant linkage on chromosome 6q22.31-q23.2. Diabetes, 53, 803-811.
    • (2004) Diabetes , vol.53 , pp. 803-811
    • Meyre, D.1    Lecoeur, C.2    Delplanque, J.3    Francke, S.4    Vatin, V.5    Durand, E.6    Weill, J.7    Dina, C.8    Froguel, P.9
  • 60
    • 34247373877 scopus 로고    scopus 로고
    • Quantitative trait locus on 15q for a metabolic syndrome variable derived from factor analysis
    • Bosse, Y., Despres, J.P., Chagnon, Y.C., Rice, T., Rao, D.C., Bouchard, C., Perusse, L. and Vohl, M.C. (2007) Quantitative trait locus on 15q for a metabolic syndrome variable derived from factor analysis. Obesity, 15, 544-550.
    • (2007) Obesity , vol.15 , pp. 544-550
    • Bosse, Y.1    Despres, J.P.2    Chagnon, Y.C.3    Rice, T.4    Rao, D.C.5    Bouchard, C.6    Perusse, L.7    Vohl, M.C.8
  • 63
    • 41949138132 scopus 로고    scopus 로고
    • ICER-1gamma overexpression drives palmitate-mediated connexin36 down-regulation in insulin-secreting cells
    • Allagnat, F., Alonso, F., Martin, D., Abderrahmani, A., Waeber, G. and Haefliger, J.A. (2008) ICER-1gamma overexpression drives palmitate-mediated connexin36 down-regulation in insulin-secreting cells. J. Biol. Chem., 283, 5226-5234.
    • (2008) J. Biol. Chem , vol.283 , pp. 5226-5234
    • Allagnat, F.1    Alonso, F.2    Martin, D.3    Abderrahmani, A.4    Waeber, G.5    Haefliger, J.A.6
  • 64
    • 0020513139 scopus 로고
    • In vivo modulation of gap junctions and dye coupling between B-cells of the intact pancreatic islet
    • Meda, P., Michaels, R.L., Halban, P.A., Orci, L. and Sheridan, J.D. (1983) In vivo modulation of gap junctions and dye coupling between B-cells of the intact pancreatic islet. Diabetes, 32, 858-868.
    • (1983) Diabetes , vol.32 , pp. 858-868
    • Meda, P.1    Michaels, R.L.2    Halban, P.A.3    Orci, L.4    Sheridan, J.D.5
  • 66
    • 0023912253 scopus 로고
    • Automated method for isolation of human pancreatic islets
    • Ricordi, C., Lacy, P.E., Finke, E.H., Olack, B.J. and Scharp, D.W. (1988) Automated method for isolation of human pancreatic islets. Diabetes, 37, 413-420.
    • (1988) Diabetes , vol.37 , pp. 413-420
    • Ricordi, C.1    Lacy, P.E.2    Finke, E.H.3    Olack, B.J.4    Scharp, D.W.5
  • 69
    • 3843101644 scopus 로고    scopus 로고
    • Oligonucleotide microarray analysis reveals PDX1 as an essential regulator of mitochondrial metabolism in rat islets
    • Gauthier, B.R., Brun, T., Sarret, E.J., Ishihara, H., Schaad, O., Descombes, P. and Wollheim, C.B. (2004) Oligonucleotide microarray analysis reveals PDX1 as an essential regulator of mitochondrial metabolism in rat islets. J. Biol. Chem., 279 (30), 31121-31130.
    • (2004) J. Biol. Chem , vol.279 , Issue.30 , pp. 31121-31130
    • Gauthier, B.R.1    Brun, T.2    Sarret, E.J.3    Ishihara, H.4    Schaad, O.5    Descombes, P.6    Wollheim, C.B.7
  • 70
    • 0026682934 scopus 로고
    • Coupling and connexin 43 expression in microvascular and large vessel endothelial cells
    • Pepper, M.S., Montesano, R., el Aoumari, A., Gros, D., Orci, L. and Meda, P. (1992) Coupling and connexin 43 expression in microvascular and large vessel endothelial cells. Am. J. Physiol., 262, C1246-C1257.
    • (1992) Am. J. Physiol , vol.262
    • Pepper, M.S.1    Montesano, R.2    el Aoumari, A.3    Gros, D.4    Orci, L.5    Meda, P.6
  • 71
    • 0036644062 scopus 로고    scopus 로고
    • Spatial raft coalescence represents an initial step in Fc gamma R signaling
    • Kono, H., Suzuki, T., Yamamoto, K., Okada, M., Yamamoto, T. and Honda, Z. (2002) Spatial raft coalescence represents an initial step in Fc gamma R signaling. J. Immunol., 169, 193-203.
    • (2002) J. Immunol , vol.169 , pp. 193-203
    • Kono, H.1    Suzuki, T.2    Yamamoto, K.3    Okada, M.4    Yamamoto, T.5    Honda, Z.6
  • 72
    • 0035879095 scopus 로고    scopus 로고
    • Glycolipid-enriched membrane domains are assembled into membrane patches by associating with the actin cytoskeleton
    • Rodgers, W. and Zavzavadjian, J. (2001) Glycolipid-enriched membrane domains are assembled into membrane patches by associating with the actin cytoskeleton. Exp. Cell Res., 267, 173-183.
    • (2001) Exp. Cell Res , vol.267 , pp. 173-183
    • Rodgers, W.1    Zavzavadjian, J.2
  • 73
    • 0035220391 scopus 로고    scopus 로고
    • Biochemical analysis of connexon assembly
    • VanSlyke, J.K. and Musil, L.S. (2001) Biochemical analysis of connexon assembly. Methods Mol. Biol., 154, 117-134.
    • (2001) Methods Mol. Biol , vol.154 , pp. 117-134
    • VanSlyke, J.K.1    Musil, L.S.2
  • 74
    • 23844553509 scopus 로고    scopus 로고
    • Expression and secretion of alpha1-proteinase inhibitor are regulated by proinflammatory cytokines in human pancreatic islet cells
    • Bosco, D., Meda, P., Morel, P., Matthey-Doret, D., Caille, D., Toso, C., Bühler, L.H. and Berney, T. (2005) Expression and secretion of alpha1-proteinase inhibitor are regulated by proinflammatory cytokines in human pancreatic islet cells. Diabetologia, 48, 1523-1233.
    • (2005) Diabetologia , vol.48 , pp. 1523-1233
    • Bosco, D.1    Meda, P.2    Morel, P.3    Matthey-Doret, D.4    Caille, D.5    Toso, C.6    Bühler, L.H.7    Berney, T.8
  • 75
    • 0034683747 scopus 로고    scopus 로고
    • Expression and function of alpha(v)beta(3) and alpha(v)beta(5) integrins in the developing pancreas: Roles in the adhesion and migration of putative endocrine progenitor cells
    • Cirulli, V., Beattie, G.M., Klier, G., Ellisman, M., Ricordi, C., Quaranta, V., Frasier, F., Ishii, J.K., Hayek, A. and Salomon, D.R. (2000) Expression and function of alpha(v)beta(3) and alpha(v)beta(5) integrins in the developing pancreas: Roles in the adhesion and migration of putative endocrine progenitor cells. J. Cell Biol., 150, 1445-1460.
    • (2000) J. Cell Biol , vol.150 , pp. 1445-1460
    • Cirulli, V.1    Beattie, G.M.2    Klier, G.3    Ellisman, M.4    Ricordi, C.5    Quaranta, V.6    Frasier, F.7    Ishii, J.K.8    Hayek, A.9    Salomon, D.R.10
  • 76
    • 0018643341 scopus 로고
    • Increase of gap junctions between pancreatic B-cells during stimulation of insulin secretion
    • Meda, P., Perrelet, A. and Orci, L. (1979) Increase of gap junctions between pancreatic B-cells during stimulation of insulin secretion. J. Cell Biol., 82, 441-448.
    • (1979) J. Cell Biol , vol.82 , pp. 441-448
    • Meda, P.1    Perrelet, A.2    Orci, L.3


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