N-Imidazolebenzyl-histidine substitution in somatostatin and in its octapeptide analogue modulates receptor selectivity and function

Journal of Medicinal Chemistry

Volumn 54, Issue 17, 2011, Pages 5981-5987

  Erchegyi, Judit ^a   Cescato, Renzo ^b   Waser, Beatrice ^b   Rivier, Jean E ^a   Reubi, Jean Claude ^b  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

HISTIDINE; LUCIFERASE; N IMIDAZOLEBENZYL HISTIDINE; OCTAPEPTIDE; SOMATOSTATIN; SOMATOSTATIN RECEPTOR; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; ENANTIOSELECTIVITY; HUMAN; HUMAN CELL; PROTEIN FUNCTION; RECEPTOR BINDING;

CELLS, CULTURED; HISTIDINE; HUMANS; IMIDAZOLES; IMMUNOENZYME TECHNIQUES; LUCIFERASES; OLIGOPEPTIDES; PEPTIDES, CYCLIC; RADIOLIGAND ASSAY; RECEPTORS, SOMATOSTATIN; SOMATOSTATIN; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 80052365882     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm200307v     Document Type: Article

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