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Volumn 34, Issue 7, 2011, Pages 1113-1123

Self-microemulsifying drug delivery system for improved oral bioavailability of dipyridamole: Preparation and evaluation

Author keywords

Dipyridamole; Dissolution; Microemulsion; Oral bioavailability; Self microemulsifying drug delivery system (SMEDDS)

Indexed keywords

2 PROPANOL; DIPYRIDAMOLE; OLEIC ACID; SOLUTOL HS 15;

EID: 80052313492     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-011-0709-8     Document Type: Article
Times cited : (42)

References (38)
  • 1
    • 0028948839 scopus 로고
    • A theoretical basis for a biopharmaceutic drug classification: The correlation of in vitro drug product dissolution and in vivo bioavailability
    • 7617530 10.1023/A:1016212804288 1:CAS:528:DyaK2MXksVGqur8%3D
    • G. L. Amidon H. Lennernäs V. P. Shah J. R. Crison 1995 A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability Pharm. Res. 12 413 420 7617530 10.1023/A:1016212804288 1:CAS:528:DyaK2MXksVGqur8%3D
    • (1995) Pharm. Res. , vol.12 , pp. 413-420
    • Amidon, G.L.1    Lennernäs, H.2    Shah, V.P.3    Crison, J.R.4
  • 2
    • 67349166936 scopus 로고    scopus 로고
    • Enhanced oral bioavailability of Coenzyme Q10 by self-emulsifying drug delivery systems
    • 19446761 10.1016/j.ijpharm.2009.03.008 1:CAS:528:DC%2BD1MXlvFGltLs%3D
    • P. Balakrishnan B. J. Lee D. H. Oh J. O. Kim Y. I. Lee D. D. Kim J. P. Jee Y. B. Lee J. S. Woo C. S. Yong H. G. Choi 2009 Enhanced oral bioavailability of Coenzyme Q10 by self-emulsifying drug delivery systems Int. J. Pharm. 374 66 72 19446761 10.1016/j.ijpharm.2009.03.008 1:CAS:528:DC%2BD1MXlvFGltLs%3D
    • (2009) Int. J. Pharm. , vol.374 , pp. 66-72
    • Balakrishnan, P.1    Lee, B.J.2    Oh, D.H.3    Kim, J.O.4    Lee, Y.I.5    Kim, D.D.6    Jee, J.P.7    Lee, Y.B.8    Woo, J.S.9    Yong, C.S.10    Choi, H.G.11
  • 3
    • 33646640645 scopus 로고    scopus 로고
    • Current industrial practices of assessing permeability and P-glycoprotein interaction
    • DOI 10.1208/aapsj080101
    • P. V. Balimane Y. H. Han S. Chong 2006 Current industrial practices of assessing permeability and Pglycoprotein interaction AAPS J. 8 E1 E13 16584115 10.1208/aapsj080101 1:CAS:528:DC%2BD28XjsVCisL4%3D (Pubitemid 43116028)
    • (2006) AAPS Journal , vol.8 , Issue.1 , pp. 1
    • Balimane, P.V.1    Han, Y.-H.2    Chong, S.3
  • 4
    • 0028818632 scopus 로고
    • Preparation of controlled-release coevaporates of dipyridamole by loading neutral pellets in a fluidized-bed coating system
    • 8570519 10.1023/A:1016253119194 1:CAS:528:DyaK2MXpslOit7g%3D
    • D. B. Beten K. Amighi A. J. Moës 1995 Preparation of controlled-release coevaporates of dipyridamole by loading neutral pellets in a fluidized-bed coating system Pharm. Res. 12 1269 1272 8570519 10.1023/A:1016253119194 1:CAS:528:DyaK2MXpslOit7g%3D
    • (1995) Pharm. Res. , vol.12 , pp. 1269-1272
    • Beten, D.B.1    Amighi, K.2    Moës, A.J.3
  • 5
    • 0036805875 scopus 로고    scopus 로고
    • Improved oral bioavailability of cyclosporin A in male Wistar rats: Comparison of a Solutol HS 15 containing self-dispersing formulation and a microsuspension
    • DOI 10.1016/S0378-5173(02)00339-3, PII S0378517302003393
    • R. C. Bravo González J. Huwyler I. Walter R. Mountfield B. Bittner 2002 Improved oral bioavailability of cyclosporin A in male Wistar rats: comparison of a Solutol HS 15 containing self-dispersing formulation and a microsuspension Int. J. Pharm. 245 143 151 12270251 10.1016/S0378-5173(02)00339- 3 (Pubitemid 35299900)
    • (2002) International Journal of Pharmaceutics , vol.245 , Issue.1-2 , pp. 143-151
    • Bravo Gonzalez, R.C.1    Huwyler, J.2    Walter, I.3    Mountfield, R.4    Bittner, B.5
  • 6
    • 0029145993 scopus 로고
    • Comparison of solutol HS 15, Cremophor EL and novel ethoxylated fatty acid surfactants as multidrug resistance modification agents
    • 7635569 10.1002/ijc.2910620413 1:CAS:528:DyaK2MXpsVWms7o%3D
    • L. E. Buckingham M. Balasubramanian R. M. Emanuele K. E. Clodfelter J. S. Coon 1995 Comparison of solutol HS 15, Cremophor EL and novel ethoxylated fatty acid surfactants as multidrug resistance modification agents Int. J. Cancer 62 436 442 7635569 10.1002/ijc.2910620413 1:CAS:528:DyaK2MXpsVWms7o%3D
    • (1995) Int. J. Cancer , vol.62 , pp. 436-442
    • Buckingham, L.E.1    Balasubramanian, M.2    Emanuele, R.M.3    Clodfelter, K.E.4    Coon, J.S.5
  • 7
    • 37849030987 scopus 로고    scopus 로고
    • Self-microemulsifying drug delivery system (SMEDDS) of vinpocetine: Formulation development and in vivo assessment
    • 18175953 10.1248/bpb.31.118 1:CAS:528:DC%2BD1cXmtlalu74%3D
    • Y. Chen G. Li X. Wu Z. Chen J. Hang B. Qin S. Chen R. Wang 2008 Self-microemulsifying drug delivery system (SMEDDS) of vinpocetine: formulation development and in vivo assessment Biol. Pharm. Bull. 31 118 125 18175953 10.1248/bpb.31.118 1:CAS:528:DC%2BD1cXmtlalu74%3D
    • (2008) Biol. Pharm. Bull. , vol.31 , pp. 118-125
    • Chen, Y.1    Li, G.2    Wu, X.3    Chen, Z.4    Hang, J.5    Qin, B.6    Chen, S.7    Wang, R.8
  • 8
    • 33645318967 scopus 로고    scopus 로고
    • Stability and pharmacokinetic studies of O-palmitoyl amylopectin anchored dipyridamole liposomes
    • 16540271 10.1016/j.ijpharm.2006.01.031 1:CAS:528:DC%2BD28XjtVGqtLc%3D
    • J. Cheng J. B. Zhu N. Wen F. Xiong 2006 Stability and pharmacokinetic studies of O-palmitoyl amylopectin anchored dipyridamole liposomes Int. J. Pharm. 313 136 143 16540271 10.1016/j.ijpharm.2006.01.031 1:CAS:528: DC%2BD28XjtVGqtLc%3D
    • (2006) Int. J. Pharm. , vol.313 , pp. 136-143
    • Cheng, J.1    Zhu, J.B.2    Wen, N.3    Xiong, F.4
  • 9
    • 2442671307 scopus 로고    scopus 로고
    • Impact of excipients on the absorption of P-glycoprotein substrates in vitro and in vivo
    • DOI 10.1016/j.ijpharm.2004.03.001, PII S037851730400170X
    • G. Cornaire J. Woodley P. Hermann A. Cloarec C. Arellano G. Houin 2004 Impact of excipients on the absorption of P-glycoprotein substrates in vitro and in vivo. Int. J. Pharm. 278 119 131 15158955 10.1016/j.ijpharm.2004.03.001 1:CAS:528:DC%2BD2cXktFOiur4%3D (Pubitemid 38670443)
    • (2004) International Journal of Pharmaceutics , vol.278 , Issue.1 , pp. 119-131
    • Cornaire, G.1    Woodley, J.2    Hermann, P.3    Cloarec, A.4    Arellano, C.5    Houin, G.6
  • 10
    • 62749095208 scopus 로고    scopus 로고
    • Enhancement of oral absorption of curcumin by selfmicroemulsifying drug delivery systems
    • 19124065 10.1016/j.ijpharm.2008.12.009 1:CAS:528:DC%2BD1MXjslWktbg%3D
    • J. Cui B. Yu Y. Zhao W. Zhu H. Li H. Lou G. Zhai 2009 Enhancement of oral absorption of curcumin by selfmicroemulsifying drug delivery systems Int. J. Pharm. 371 148 155 19124065 10.1016/j.ijpharm.2008.12.009 1:CAS:528: DC%2BD1MXjslWktbg%3D
    • (2009) Int. J. Pharm. , vol.371 , pp. 148-155
    • Cui, J.1    Yu, B.2    Zhao, Y.3    Zhu, W.4    Li, H.5    Lou, H.6    Zhai, G.7
  • 11
    • 34250867442 scopus 로고    scopus 로고
    • The effect of different lipid based formulations on the oral absorption of lipophilic drugs: The ability of in vitro lipolysis and consecutive ex vivo intestinal permeability data to predict in vivo bioavailability in rats
    • DOI 10.1016/j.ejpb.2007.01.017, PII S0939641107000227
    • A. Dahan A. Hoffman 2007 The effect of different lipid based formulations on the oral absorption of lipophilic drugs: the ability of in vitro lipolysis and consecutive ex vivo intestinal permeability data to predict in vivo bioavailability in rats Eur. J. Pharm. Biopharm. 67 96 105 17329087 10.1016/j.ejpb.2007.01.017 1:CAS:528:DC%2BD2sXntF2lsrg%3D (Pubitemid 46991342)
    • (2007) European Journal of Pharmaceutics and Biopharmaceutics , vol.67 , Issue.1 , pp. 96-105
    • Dahan, A.1    Hoffman, A.2
  • 12
    • 33646547331 scopus 로고    scopus 로고
    • Microemulsions: A potential drug delivery system
    • DOI 10.2174/156720106776359168
    • P. K. Ghosh R. S. Murthy 2006 Microemulsions: a potential drug delivery system Curr. Drug Deliv. 3 167 180 16611003 10.2174/156720106776359168 1:CAS:528:DC%2BD28XjvFWitbc%3D (Pubitemid 43725014)
    • (2006) Current Drug Delivery , vol.3 , Issue.2 , pp. 167-180
    • Ghosh, P.K.1    Murthy, R.S.R.2
  • 13
    • 33749057113 scopus 로고    scopus 로고
    • Design and development of microemulsion drug delivery system of acyclovir for improvement of oral bioavailability
    • 17025257 10.1208/pt070377
    • P. K. Ghosh R. J. Majithiya M. L. Umrethia R. S. Murthy 2006 Design and development of microemulsion drug delivery system of acyclovir for improvement of oral bioavailability AAPS PharmSciTech 7 77 17025257 10.1208/pt070377
    • (2006) AAPS PharmSciTech , vol.7 , pp. 77
    • Ghosh, P.K.1    Majithiya, R.J.2    Umrethia, M.L.3    Murthy, R.S.4
  • 14
    • 1842684453 scopus 로고    scopus 로고
    • Self-emulsifying drug delivery systems (SEDDS) for improved oral delivery of lipophilic drugs
    • DOI 10.1016/j.biopha.2004.02.001, PII S0753332204000319
    • R. N. Gursoy S. Benita 2004 Self-emulsifying drug delivery systems (SEDDS) for improved oral delivery of lipophilic drugs Biomed. Pharmacother. 58 173 182 15082340 10.1016/j.biopha.2004.02.001 (Pubitemid 38479922)
    • (2004) Biomedicine and Pharmacotherapy , vol.58 , Issue.3 , pp. 173-182
    • Gursoy, R.N.1    Benita, S.2
  • 15
    • 33745815950 scopus 로고    scopus 로고
    • Applications of microemulsion based drug delivery system
    • DOI 10.2174/156720106777731118
    • K. R. Jadhav I. M. Shaikh K. W. Ambade V. J. Kadam 2006 Applications of microemulsion based drug delivery system Curr. Drug Deliv. 3 267 273 16848728 10.2174/156720106777731118 1:CAS:528:DC%2BD28Xms1Clu7o%3D (Pubitemid 44031625)
    • (2006) Current Drug Delivery , vol.3 , Issue.3 , pp. 267-273
    • Jadhav, K.R.1    Shaikh, I.M.2    Ambade, K.W.3    Kadam, V.J.4
  • 16
    • 0024335311 scopus 로고
    • Modulation of 5-fluorouracil and 5-fluorouridine toxicity by membrane transport inhibitors in normal tissues of rats with liver adenocarcinoma
    • B. Jakobsson I. A. el Hag C. Erichsen P. I. Christensson P. E. Jönsson U. Stenram 1989 Modulation of 5-fluorouracil and 5-fluorouridine toxicity by membrane transport inhibitors in normal tissues of rats with liver adenocarcinoma Anticancer Res. 9 285 290 2751255 1:CAS:528:DyaL1MXlsVKgtb4%3D (Pubitemid 19174627)
    • (1989) Anticancer Research , vol.9 , Issue.2 , pp. 285-290
    • Jakobsson, B.1    El Hag, I.A.2    Erichsen, C.3    Christensson, P.-I.4    Jonsson, P.-E.5    Stenram, U.6
  • 17
    • 44849119532 scopus 로고    scopus 로고
    • Design and evaluation of self-emulsifying drug delivery systems (SEDDS) of nimodipine
    • 18446481 10.1208/s12249-008-9037-9 1:CAS:528:DC%2BC3cXosFGnt7k%3D
    • A. A. Kale V. B. Patravale 2008 Design and evaluation of self-emulsifying drug delivery systems (SEDDS) of nimodipine AAPS PharmSciTech 9 191 196 18446481 10.1208/s12249-008-9037-9 1:CAS:528:DC%2BC3cXosFGnt7k%3D
    • (2008) AAPS PharmSciTech , vol.9 , pp. 191-196
    • Kale, A.A.1    Patravale, V.B.2
  • 18
    • 0032103706 scopus 로고    scopus 로고
    • Formulation design and bioavailability assessment of lipidic self- emulsifying formulations of halofantrine
    • DOI 10.1016/S0378-5173(98)00054-4, PII S0378517398000544
    • S. M. Khoo A. J. Humberstone C. J. H. Porter G. A. Edwards W. N. Charman 1998 Formulation design and bioavailability assessment of lipidic self-emulsifying formulations of halofantrine Int. J. Pharm. 167 155 164 10.1016/S0378-5173(98)00054-4 1:CAS:528:DyaK1cXksF2mu7s%3D (Pubitemid 28341517)
    • (1998) International Journal of Pharmaceutics , vol.167 , Issue.1-2 , pp. 155-164
    • Khoo, S.-M.1    Humberstone, A.J.2    Porter, C.J.H.3    Edwards, G.A.4    Charman, W.N.5
  • 19
    • 0026545273 scopus 로고
    • Evaluation of pH-independent sustained-release granules of dipyridamole by using gastric-acidity-controlled rabbits and human subjects
    • 10.1016/0378-5173(92)90042-Z 1:CAS:528:DyaK38Xit1WntLs%3D
    • N. Kohri N. Miyata M. Takahashi H. Endo K. Iseki K. Miyazaki S. Takechi A. Nomura 1992 Evaluation of pH-independent sustained-release granules of dipyridamole by using gastric-acidity-controlled rabbits and human subjects Int. J. Pharm. 81 49 58 10.1016/0378-5173(92)90042-Z 1:CAS:528:DyaK38Xit1WntLs%3D
    • (1992) Int. J. Pharm. , vol.81 , pp. 49-58
    • Kohri, N.1    Miyata, N.2    Takahashi, M.3    Endo, H.4    Iseki, K.5    Miyazaki, K.6    Takechi, S.7    Nomura, A.8
  • 20
    • 57049152323 scopus 로고    scopus 로고
    • Optimization and in situ intestinal absorption of selfmicroemulsifying drug delivery system of oridonin
    • 18782611 10.1016/j.ijpharm.2008.08.009 1:CAS:528:DC%2BD1cXhsVKnur7P
    • Y. Liu P. Zhang N. Feng X. Zhang S. Wu J. Zhao 2009 Optimization and in situ intestinal absorption of selfmicroemulsifying drug delivery system of oridonin Int. J. Pharm. 365 136 142 18782611 10.1016/j.ijpharm.2008.08.009 1:CAS:528:DC%2BD1cXhsVKnur7P
    • (2009) Int. J. Pharm. , vol.365 , pp. 136-142
    • Liu, Y.1    Zhang, P.2    Feng, N.3    Zhang, X.4    Wu, S.5    Zhao, J.6
  • 21
    • 67549143093 scopus 로고    scopus 로고
    • Preparation and evaluation of self-nanoemulsifying tablets of carvedilol
    • 19238556 10.1208/s12249-009-9192-7 1:CAS:528:DC%2BC3cXotV2mtbk%3D
    • E. A. Mahmoud E. R. Bendas M. I. Mohamed 2009 Preparation and evaluation of self-nanoemulsifying tablets of carvedilol AAPS PharmSciTech 10 183 192 19238556 10.1208/s12249-009-9192-7 1:CAS:528:DC%2BC3cXotV2mtbk%3D
    • (2009) AAPS PharmSciTech , vol.10 , pp. 183-192
    • Mahmoud, E.A.1    Bendas, E.R.2    Mohamed, M.I.3
  • 22
    • 0035984949 scopus 로고    scopus 로고
    • Lipid-based formulations for intestinal lymphatic delivery
    • DOI 10.1016/S0928-0987(02)00051-9, PII S0928098702000519
    • C. M. O'Driscoll 2002 Lipid-based formulations for intestinal lymphatic delivery Eur. J. Pharm. Sci. 15 405 415 12036717 10.1016/S0928-0987(02)00051-9 (Pubitemid 34567104)
    • (2002) European Journal of Pharmaceutical Sciences , vol.15 , Issue.5 , pp. 405-415
    • O'Driscoll, C.M.1
  • 23
    • 37549031769 scopus 로고    scopus 로고
    • Oral bioavailability enhancement of acyclovir by self-microemulsifying drug delivery systems (SMEDDS)
    • 18097805 10.1080/03639040701385527 1:CAS:528:DC%2BD2sXhsVCgsL3M
    • D. Patel K. K. Sawant 2007 Oral bioavailability enhancement of acyclovir by self-microemulsifying drug delivery systems (SMEDDS) Drug Dev. Ind. Pharm. 33 1318 1326 18097805 10.1080/03639040701385527 1:CAS:528:DC%2BD2sXhsVCgsL3M
    • (2007) Drug Dev. Ind. Pharm. , vol.33 , pp. 1318-1326
    • Patel, D.1    Sawant, K.K.2
  • 24
    • 68949135410 scopus 로고    scopus 로고
    • Self micro-emulsifying drug delivery system: Formulation development and biopharmaceutical evaluation of lipophilic drugs
    • 19534704 10.2174/156720109789000519 1:CAS:528:DC%2BD1MXhtFKksrzJ
    • D. Patel K. K. Sawant 2009 Self micro-emulsifying drug delivery system: formulation development and biopharmaceutical evaluation of lipophilic drugs Curr. Drug Deliv. 6 419 424 19534704 10.2174/156720109789000519 1:CAS:528:DC%2BD1MXhtFKksrzJ
    • (2009) Curr. Drug Deliv. , vol.6 , pp. 419-424
    • Patel, D.1    Sawant, K.K.2
  • 25
    • 34247467447 scopus 로고    scopus 로고
    • Statistical evaluation of influence of xanthan gum and guar gum blends on dipyridamole release from floating matrix tablets
    • DOI 10.1080/03639040601050155, PII 777595481
    • V. F. Patel N. M. Patel 2007 Statistical evaluation of influence of xanthan gum and guar gum blends on dipyridamole release from floating matrix tablets Drug Dev. Ind. Pharm. 33 327 334 17454065 10.1080/03639040601050155 1:CAS:528:DC%2BD2sXltVeisL4%3D (Pubitemid 46650748)
    • (2007) Drug Development and Industrial Pharmacy , vol.33 , Issue.3 , pp. 327-334
    • Patel, V.F.1    Patel, N.M.2
  • 26
    • 50249132541 scopus 로고    scopus 로고
    • Self-nanoemulsifying drug delivery systems (SNEDDS) for oral delivery of protein drugs: I. Formulation development
    • 18650038 10.1016/j.ijpharm.2008.05.018 1:CAS:528:DC%2BD1cXhtVGjsLzN
    • S. V. R. Rao J. Shao 2008 Self-nanoemulsifying drug delivery systems (SNEDDS) for oral delivery of protein drugs: I. Formulation development Int. J. Pharm. 362 2 9 18650038 10.1016/j.ijpharm.2008.05.018 1:CAS:528: DC%2BD1cXhtVGjsLzN
    • (2008) Int. J. Pharm. , vol.362 , pp. 2-9
    • Rao, S.V.R.1    Shao, J.2
  • 27
    • 15244353232 scopus 로고    scopus 로고
    • Effect of self-microemulsifying drug delivery systems containing Labrasol on tight junctions in Caco-2 cells
    • DOI 10.1016/j.ejps.2005.01.001
    • X. Sha G. Yan Y. Wu J. Li X. Fang 2005 Effect of selfmicroemulsifying drug delivery systems containing Labrasol on tight junctions in Caco-2 cells Eur. J. Pharm. Sci. 24 477 486 15784337 10.1016/j.ejps.2005.01.001 1:CAS:528:DC%2BD2MXisFGksbc%3D (Pubitemid 40387261)
    • (2005) European Journal of Pharmaceutical Sciences , vol.24 , Issue.5 , pp. 477-486
    • Sha, X.1    Yan, G.2    Wu, Y.3    Li, J.4    Fang, X.5
  • 28
    • 64149103691 scopus 로고    scopus 로고
    • High performance liquid chromatography method for the pharmacokinetic study of bicalutamide SMEDDS and suspension formulations after oral administration to rats
    • 19362193 10.1016/j.talanta.2009.01.058 1:CAS:528:DC%2BD1MXksVWhsro%3D
    • A. K. Singh A. Chaurasiya G. K. Jain A. Awasthi D. Asati G. Mishra R. K. Khar R. Mukherjee 2009 High performance liquid chromatography method for the pharmacokinetic study of bicalutamide SMEDDS and suspension formulations after oral administration to rats Talanta 78 1310 1314 19362193 10.1016/j.talanta. 2009.01.058 1:CAS:528:DC%2BD1MXksVWhsro%3D
    • (2009) Talanta , vol.78 , pp. 1310-1314
    • Singh, A.K.1    Chaurasiya, A.2    Jain, G.K.3    Awasthi, A.4    Asati, D.5    Mishra, G.6    Khar, R.K.7    Mukherjee, R.8
  • 29
    • 23244432152 scopus 로고    scopus 로고
    • The use of an in vitro dissolution and absorption system to evaluate oral absorption of two weak bases in pH-independent controlled-release formulations
    • DOI 10.1016/j.ejps.2005.02.017, PII S0928098705001673
    • M. Sugawara S. Kadomura X. He Y. Takekuma N. Kohri K. Miyazaki 2005 The use of an in vitro dissolution and absorption system to evaluate oral absorption of two weak bases in pH-independent controlled-release formulations Eur. J. Pharm. Sci. 26 1 8 15961297 10.1016/j.ejps.2005.02.017 1:CAS:528: DC%2BD2MXntVCqu7k%3D (Pubitemid 41097255)
    • (2005) European Journal of Pharmaceutical Sciences , vol.26 , Issue.1 , pp. 1-8
    • Sugawara, M.1    Kadomura, S.2    He, X.3    Takekuma, Y.4    Kohri, N.5    Miyazaki, K.6
  • 30
    • 0022459112 scopus 로고
    • The absolute and relative bioavailability of dipyridamole from different preparations and the in vitro-in vivo comparison
    • B. Terhaag F. Donath G. Le Petit K. Feller 1986 The absolute and relative bioavailability of dipyridamole from different preparations and the in vitro-in vivo comparison Int. J. Clin. Pharmacol. Ther. Toxicol. 24 298 302 3733279 1:CAS:528:DyaL28XkvVGjtb0%3D (Pubitemid 16084158)
    • (1986) International Journal of Clinical Pharmacology Therapy and Toxicology , vol.24 , Issue.6 , pp. 298-302
    • Terhaag, B.1    Donath, F.2    Le Petit, G.3    Feller, K.4
  • 31
    • 33746057821 scopus 로고    scopus 로고
    • Functional role of P-glycoprotein in limiting peroral drug absorption: optimizing drug delivery
    • DOI 10.1016/j.cbpa.2006.06.015, PII S1367593106000846, Next-Generation Therapeutics
    • M. V. Varma O. P. Perumal R. Panchagnula 2006 Functional role of P-glycoprotein in limiting peroral drug absorption: optimizing drug delivery Curr. Opin. Chem. Biol. 10 367 373 16814593 10.1016/j.cbpa.2006.06.015 1:CAS:528:DC%2BD28XntlGitbk%3D (Pubitemid 44080650)
    • (2006) Current Opinion in Chemical Biology , vol.10 , Issue.4 , pp. 367-373
    • Varma, M.V.1    Perumal, O.P.2    Panchagnula, R.3
  • 33
    • 67549123935 scopus 로고    scopus 로고
    • Formulation development and bioavailability evaluation of a self-nanoemulsified drug delivery system of oleanolic acid
    • 19224372 10.1208/s12249-009-9190-9 1:CAS:528:DC%2BC3cXotV2mtbg%3D
    • J. Xi Q. Chang C. K. Chan Z. Y. Meng G. N. Wang J. B. Sun Y. T. Wang H. H. Tong Y. Zheng 2009 Formulation development and bioavailability evaluation of a self-nanoemulsified drug delivery system of oleanolic acid AAPS PharmSciTech 10 172 182 19224372 10.1208/s12249-009-9190-9 1:CAS:528:DC%2BC3cXotV2mtbg%3D
    • (2009) AAPS PharmSciTech , vol.10 , pp. 172-182
    • Xi, J.1    Chang, Q.2    Chan, C.K.3    Meng, Z.Y.4    Wang, G.N.5    Sun, J.B.6    Wang, Y.T.7    Tong, H.H.8    Zheng, Y.9
  • 34
    • 58149125516 scopus 로고    scopus 로고
    • Preparation of nobiletin in self-microemulsifying systems and its intestinal permeability in rats
    • 18801304 1:CAS:528:DC%2BD1MXht1Clsb3K
    • J. Yao Y. Lu J. P. Zhou 2008 Preparation of nobiletin in self-microemulsifying systems and its intestinal permeability in rats J. Pharm. Pharm. Sci. 11 22 29 18801304 1:CAS:528:DC%2BD1MXht1Clsb3K
    • (2008) J. Pharm. Pharm. Sci. , vol.11 , pp. 22-29
    • Yao, J.1    Lu, Y.2    Zhou, J.P.3
  • 35
    • 70350618790 scopus 로고    scopus 로고
    • Docetaxel microemulsion for enhanced oral bioavailability: Preparation and in vitro and in vivo evaluation
    • 19709639 10.1016/j.jconrel.2009.08.015 1:CAS:528:DC%2BD1MXhtlOks73E
    • Y. M. Yin F. D. Cui C. F. Mu M. K. Choi J. S. Kim S. J. Chung C. K. Shim D. D. Kim 2009 Docetaxel microemulsion for enhanced oral bioavailability: preparation and in vitro and in vivo evaluation J. Control. Release 140 86 94 19709639 10.1016/j.jconrel.2009.08.015 1:CAS:528:DC%2BD1MXhtlOks73E
    • (2009) J. Control. Release , vol.140 , pp. 86-94
    • Yin, Y.M.1    Cui, F.D.2    Mu, C.F.3    Choi, M.K.4    Kim, J.S.5    Chung, S.J.6    Shim, C.K.7    Kim, D.D.8
  • 36
    • 29244448268 scopus 로고    scopus 로고
    • BCRP transports dipyridamole and is inhibited by calcium channel blockers
    • DOI 10.1007/s11095-005-8384-4
    • Y. Zhang A. Gupta H. Wang L. Zhou R. R. Vethanayagam J. D. Unadkat Q. Mao 2005 BCRP transports dipyridamole and is inhibited by calcium channel blockers Pharm. Res. 22 2023 2034 16247709 10.1007/s11095-005-8384-4 1:CAS:528: DC%2BD2MXhtlemtbnF (Pubitemid 41821581)
    • (2005) Pharmaceutical Research , vol.22 , Issue.12 , pp. 2023-2034
    • Zhang, Y.1    Gupta, A.2    Wang, H.3    Zhou, L.4    Vethanayagam, R.R.5    Unadkat, J.D.6    Mao, Q.7
  • 37
    • 20144387782 scopus 로고    scopus 로고
    • pH-dependent dissolution in Vitro and absorption in Vivo of weakly basic drugs: Development of a canine model
    • DOI 10.1007/s11095-004-1185-3
    • R. Zhou P. Moench C. Heran X. Lu N. Mathias T. N. Faria D. A. Wall M. A. Hussain R. L. Smith D. Sun 2005 pH-dependent dissolution in vitro and absorption in vivo of weakly basic drugs: development of a canine model Pharm. Res. 22 188 192 15783065 10.1007/s11095-004-1185-3 1:CAS:528:DC%2BD2MXitlClt74%3D (Pubitemid 40487201)
    • (2005) Pharmaceutical Research , vol.22 , Issue.2 , pp. 188-192
    • Zhou, R.1    Moench, P.2    Heran, C.3    Lu, X.4    Mathias, N.5    Faria, T.N.6    Wall, D.A.7    Hussain, M.A.8    Smith, R.L.9    Sun, D.10
  • 38
    • 76549111302 scopus 로고    scopus 로고
    • Microencapsulation of self-microemulsifying system: Improving solubility and permeability of furosemide
    • 20060454 10.1016/j.ijpharm.2009.12.055 1:CAS:528:DC%2BC3cXit1SgsLY%3D
    • A. Zvonar K. Berginc A. Kristl M. Gašperlin 2010 Microencapsulation of self-microemulsifying system: improving solubility and permeability of furosemide Int. J. Pharm. 388 151 158 20060454 10.1016/j.ijpharm.2009.12.055 1:CAS:528:DC%2BC3cXit1SgsLY%3D
    • (2010) Int. J. Pharm. , vol.388 , pp. 151-158
    • Zvonar, A.1    Berginc, K.2    Kristl, A.3    Gašperlin, M.4


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