메뉴 건너뛰기




Volumn 10, Issue 4, 2011, Pages 422-427

CD8 T cell responses to influenza virus infection in aged mice

Author keywords

Aged mice; CD8 T cell; Influenza virus

Indexed keywords

AGE; AGING; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL FUNCTION; CELL INTERACTION; CELLULAR IMMUNITY; DENDRITIC CELL; HELPER CELL; IMMUNOFLUORESCENCE; INFLUENZA; INFLUENZA VIRUS; MOLECULAR MECHANICS; NONHUMAN; REGULATORY T LYMPHOCYTE; REVIEW;

EID: 80052313290     PISSN: 15681637     EISSN: 18729649     Source Type: Journal    
DOI: 10.1016/j.arr.2011.02.001     Document Type: Review
Times cited : (46)

References (80)
  • 1
    • 60549106099 scopus 로고    scopus 로고
    • Clonal expansions and loss of receptor diversity in the naive CD8 T cell repertoire of aged mice
    • Ahmed M., Lanzer K.G., Yager E.J., Adams P.S., Johnson L.L., Blackman M.A. Clonal expansions and loss of receptor diversity in the naive CD8 T cell repertoire of aged mice. J. Immunol. 2009, 182:784-792.
    • (2009) J. Immunol. , vol.182 , pp. 784-792
    • Ahmed, M.1    Lanzer, K.G.2    Yager, E.J.3    Adams, P.S.4    Johnson, L.L.5    Blackman, M.A.6
  • 2
    • 35548997439 scopus 로고    scopus 로고
    • Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic
    • Ahmed R., Oldstone M.B., Palese P. Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic. Nat. Immunol. 2007, 8:1188-1193.
    • (2007) Nat. Immunol. , vol.8 , pp. 1188-1193
    • Ahmed, R.1    Oldstone, M.B.2    Palese, P.3
  • 4
    • 41749126024 scopus 로고
    • The susceptibility of mice to the viruses of human and swine influenza
    • Andrewers C.H., Laidlaw P.P., Smith W. The susceptibility of mice to the viruses of human and swine influenza. Lancet 1934, 224:859-862.
    • (1934) Lancet , vol.224 , pp. 859-862
    • Andrewers, C.H.1    Laidlaw, P.P.2    Smith, W.3
  • 5
    • 0036801709 scopus 로고    scopus 로고
    • The assessment of antigen-specific CD8+ T cells through the combination of MHC class I tetramer and intracellular staining
    • Appay V., Rowland-Jones S.L. The assessment of antigen-specific CD8+ T cells through the combination of MHC class I tetramer and intracellular staining. J. Immunol. Methods 2002, 268:9-19.
    • (2002) J. Immunol. Methods , vol.268 , pp. 9-19
    • Appay, V.1    Rowland-Jones, S.L.2
  • 7
    • 0034027174 scopus 로고    scopus 로고
    • A previously unrecognized H-2D(b)-restricted peptide prominent in the primary influenza A virus-specific CD8(+) T-cell response is much less apparent following secondary challenge
    • Belz G.T., Xie W., Altman J.D., Doherty P.C. A previously unrecognized H-2D(b)-restricted peptide prominent in the primary influenza A virus-specific CD8(+) T-cell response is much less apparent following secondary challenge. J. Virol. 2000, 74:3486-3493.
    • (2000) J. Virol. , vol.74 , pp. 3486-3493
    • Belz, G.T.1    Xie, W.2    Altman, J.D.3    Doherty, P.C.4
  • 8
    • 0025821667 scopus 로고
    • Influenza in senescent mice: impaired cytotoxic T-lymphocyte activity is correlated with prolonged infection
    • Bender B.S., Johnson M.P., Small P.A. Influenza in senescent mice: impaired cytotoxic T-lymphocyte activity is correlated with prolonged infection. Immunology 1991, 72:514-519.
    • (1991) Immunology , vol.72 , pp. 514-519
    • Bender, B.S.1    Johnson, M.P.2    Small, P.A.3
  • 9
    • 0027140283 scopus 로고
    • Unexpected expansions of CD8-bearing cells in old mice
    • Callahan J.E., Kappler J.W., Marrack P. Unexpected expansions of CD8-bearing cells in old mice. J. Immunol. 1993, 151:6657-6669.
    • (1993) J. Immunol. , vol.151 , pp. 6657-6669
    • Callahan, J.E.1    Kappler, J.W.2    Marrack, P.3
  • 10
    • 0023772130 scopus 로고
    • Induction of cytotoxic T lymphocytes by primary in vitro stimulation with peptides
    • Carbone F.R., Moore M.W., Sheil J.M., Bevan M.J. Induction of cytotoxic T lymphocytes by primary in vitro stimulation with peptides. J. Exp. Med. 1988, 167:1767-1779.
    • (1988) J. Exp. Med. , vol.167 , pp. 1767-1779
    • Carbone, F.R.1    Moore, M.W.2    Sheil, J.M.3    Bevan, M.J.4
  • 12
    • 77950958001 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention (CDC), Update: Influenza Activity-United States, August 30, 2009-March 27, 2010 and Composition of the 2010-11 Influenza Vaccine. MMWR 59, 423-430.
    • Centers for Disease Control and Prevention (CDC), 2010. Update: Influenza Activity-United States, August 30, 2009-March 27, 2010 and Composition of the 2010-11 Influenza Vaccine. MMWR 59, 423-430.
    • (2010)
  • 13
    • 0025873357 scopus 로고
    • The binding affinity and dissociation rates of peptides for class I major histocompatibility complex molecules
    • Cerundolo V., Elliott T., Elvin J., Bastin J., Rammensee H.G., Townsend A. The binding affinity and dissociation rates of peptides for class I major histocompatibility complex molecules. Eur. J. Immunol. 1991, 21:2069-2075.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 2069-2075
    • Cerundolo, V.1    Elliott, T.2    Elvin, J.3    Bastin, J.4    Rammensee, H.G.5    Townsend, A.6
  • 14
    • 37349112715 scopus 로고    scopus 로고
    • Increased Foxp3(+) Treg cell activity reduces dendritic cell co-stimulatory molecule expression in aged mice
    • Chiu B.C., Stolberg V.R., Zhang H., Chensue S.W. Increased Foxp3(+) Treg cell activity reduces dendritic cell co-stimulatory molecule expression in aged mice. Mech. Ageing Dev. 2007, 128:618-627.
    • (2007) Mech. Ageing Dev. , vol.128 , pp. 618-627
    • Chiu, B.C.1    Stolberg, V.R.2    Zhang, H.3    Chensue, S.W.4
  • 15
    • 0026793582 scopus 로고
    • Molecular detection and in vivo analysis of the specific T cell response to a protein antigen
    • Cochet M., Pannetier C., Regnault A., Darche S., Leclerc C., Kourilsky P. Molecular detection and in vivo analysis of the specific T cell response to a protein antigen. Eur. J. Immunol. 1992, 22:2639-2647.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 2639-2647
    • Cochet, M.1    Pannetier, C.2    Regnault, A.3    Darche, S.4    Leclerc, C.5    Kourilsky, P.6
  • 16
    • 0043076183 scopus 로고    scopus 로고
    • Differential antigen presentation regulates the changing patterns of CD8+ T cell immunodominance in primary and secondary influenza virus infections
    • Crowe S.R., Turner S.J., Miller S.C., Roberts A.D., Rappolo R.A., Doherty P.C., Ely K.H., Woodland D.L. Differential antigen presentation regulates the changing patterns of CD8+ T cell immunodominance in primary and secondary influenza virus infections. J. Exp. Med. 2003, 198:399-410.
    • (2003) J. Exp. Med. , vol.198 , pp. 399-410
    • Crowe, S.R.1    Turner, S.J.2    Miller, S.C.3    Roberts, A.D.4    Rappolo, R.A.5    Doherty, P.C.6    Ely, K.H.7    Woodland, D.L.8
  • 17
    • 0027163489 scopus 로고
    • Prominent usage of V beta 8.3 T cells in the H-2Db-restricted response to an influenza A virus nucleoprotein epitope
    • Deckhut A.M., Allan W., McMickle A., Eichelberger M., Blackman M.A., Doherty P.C., Woodland D.L. Prominent usage of V beta 8.3 T cells in the H-2Db-restricted response to an influenza A virus nucleoprotein epitope. J. Immunol. 1993, 151:2658-2666.
    • (1993) J. Immunol. , vol.151 , pp. 2658-2666
    • Deckhut, A.M.1    Allan, W.2    McMickle, A.3    Eichelberger, M.4    Blackman, M.A.5    Doherty, P.C.6    Woodland, D.L.7
  • 18
    • 77954478724 scopus 로고    scopus 로고
    • Cell-intrinsic defects in the proliferative response of antiviral memory CD8 T cells in aged mice upon secondary infection
    • Decman V., Laidlaw B.J., Dimenna L.J., Abdulla S., Mozdzanowska K., Erikson J., Ertl H.C., Wherry E.J. Cell-intrinsic defects in the proliferative response of antiviral memory CD8 T cells in aged mice upon secondary infection. J. Immunol. 2010, 184:5151-5159.
    • (2010) J. Immunol. , vol.184 , pp. 5151-5159
    • Decman, V.1    Laidlaw, B.J.2    Dimenna, L.J.3    Abdulla, S.4    Mozdzanowska, K.5    Erikson, J.6    Ertl, H.C.7    Wherry, E.J.8
  • 19
    • 55849129637 scopus 로고    scopus 로고
    • Toward a broadly protective influenza vaccine
    • Doherty P.C., Kelso A. Toward a broadly protective influenza vaccine. J. Clin. Invest. 2008, 118:3273-3275.
    • (2008) J. Clin. Invest. , vol.118 , pp. 3273-3275
    • Doherty, P.C.1    Kelso, A.2
  • 20
    • 0020519752 scopus 로고
    • Diminished T-cell response to influenza virus in aged mice
    • Effros R.B., Walford R.L. Diminished T-cell response to influenza virus in aged mice. Immunology 1983, 49:387-392.
    • (1983) Immunology , vol.49 , pp. 387-392
    • Effros, R.B.1    Walford, R.L.2
  • 21
    • 35748976568 scopus 로고    scopus 로고
    • Antigen-specific CD8+ T cell clonal expansions develop from memory T cell pools established by acute respiratory virus infections
    • Ely K.H., Ahmed M., Kohlmeier J.E., Roberts A.D., Wittmer S.T., Blackman M.A., Woodland D.L. Antigen-specific CD8+ T cell clonal expansions develop from memory T cell pools established by acute respiratory virus infections. J. Immunol. 2007, 179:3535-3542.
    • (2007) J. Immunol. , vol.179 , pp. 3535-3542
    • Ely, K.H.1    Ahmed, M.2    Kohlmeier, J.E.3    Roberts, A.D.4    Wittmer, S.T.5    Blackman, M.A.6    Woodland, D.L.7
  • 23
    • 0028220953 scopus 로고
    • Circulating T cell repertoire complexity in normal individuals and bone marrow recipients analyzed by CDR3 size spectratyping Correlation with immune status
    • Gorski J., Yassai M., Zhu X., Kissela B., Keever C., Flomenberg N. Circulating T cell repertoire complexity in normal individuals and bone marrow recipients analyzed by CDR3 size spectratyping Correlation with immune status. J. Immunol. 1994, 152(15):5109-5119.
    • (1994) J. Immunol. , vol.152 , Issue.15 , pp. 5109-5119
    • Gorski, J.1    Yassai, M.2    Zhu, X.3    Kissela, B.4    Keever, C.5    Flomenberg, N.6
  • 24
    • 32044433093 scopus 로고    scopus 로고
    • Longitudinal studies of clonally expanded CD8 T cells reveal a repertoire shrinkage predicting mortality and an increased number of dysfunctional cytomegalovirus-specific T cells in the very elderly
    • Hadrup S.R., Strindhall J., Kollgaard T., Seremet T., Johansson B., Pawelec G., thor Straten P., Wikby A. Longitudinal studies of clonally expanded CD8 T cells reveal a repertoire shrinkage predicting mortality and an increased number of dysfunctional cytomegalovirus-specific T cells in the very elderly. J. Immunol. 2006, 176:2645-2653.
    • (2006) J. Immunol. , vol.176 , pp. 2645-2653
    • Hadrup, S.R.1    Strindhall, J.2    Kollgaard, T.3    Seremet, T.4    Johansson, B.5    Pawelec, G.6    thor Straten, P.7    Wikby, A.8
  • 26
    • 0344304396 scopus 로고    scopus 로고
    • CD4 T cell memory derived from young naive cells functions well into old age, but memory generated from aged naive cells functions poorly
    • Haynes L., Eaton S.M., Burns E.M., Randall T.D., Swain S.L. CD4 T cell memory derived from young naive cells functions well into old age, but memory generated from aged naive cells functions poorly. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:15053-15058.
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 15053-15058
    • Haynes, L.1    Eaton, S.M.2    Burns, E.M.3    Randall, T.D.4    Swain, S.L.5
  • 27
    • 0033975580 scopus 로고    scopus 로고
    • The defects in effector generation associated with aging can be reversed by addition of IL-2 but not other related gamma(c)-receptor binding cytokines
    • Haynes L., Eaton S.M., Swain S.L. The defects in effector generation associated with aging can be reversed by addition of IL-2 but not other related gamma(c)-receptor binding cytokines. Vaccine 2000, 18:1649-1653.
    • (2000) Vaccine , vol.18 , pp. 1649-1653
    • Haynes, L.1    Eaton, S.M.2    Swain, S.L.3
  • 28
    • 0033523712 scopus 로고    scopus 로고
    • Interleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice
    • Haynes L., Linton P.J., Eaton S.M., Tonkonogy S.L., Swain S.L. Interleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice. J. Exp. Med. 1999, 190:1013-1024.
    • (1999) J. Exp. Med. , vol.190 , pp. 1013-1024
    • Haynes, L.1    Linton, P.J.2    Eaton, S.M.3    Tonkonogy, S.L.4    Swain, S.L.5
  • 29
    • 9244254815 scopus 로고
    • Antigen presentation: untapped peptides
    • Heemels M.T., Ploegh H. Antigen presentation: untapped peptides. Curr. Biol. 1993, 3:380-383.
    • (1993) Curr. Biol. , vol.3 , pp. 380-383
    • Heemels, M.T.1    Ploegh, H.2
  • 30
    • 77949824961 scopus 로고    scopus 로고
    • Incidence of 2009 pandemic influenza A H1N1 infection in England: a cross-sectional serological study
    • Miller E., Hoschler K., Hardelid P., Stanford E., Andrews N., Zambon M. Incidence of 2009 pandemic influenza A H1N1 infection in England: a cross-sectional serological study. Lancet 2010, 375:1100-1118.
    • (2010) Lancet , vol.375 , pp. 1100-1118
    • Miller, E.1    Hoschler, K.2    Hardelid, P.3    Stanford, E.4    Andrews, N.5    Zambon, M.6
  • 32
    • 34247877512 scopus 로고    scopus 로고
    • Mucosal dendritic cells
    • Iwasaki A. Mucosal dendritic cells. Annu. Rev. Immunol. 2007, 25:381-418.
    • (2007) Annu. Rev. Immunol. , vol.25 , pp. 381-418
    • Iwasaki, A.1
  • 34
    • 0141955151 scopus 로고    scopus 로고
    • Cuttine edge: T cells from aged mice are resistant to depletion early during virus infection
    • Jiang J., Anaraki F., Blank K.J., Murasko D.M. Cuttine edge: T cells from aged mice are resistant to depletion early during virus infection. J. Immunol. 2003, 171:3353-3357.
    • (2003) J. Immunol. , vol.171 , pp. 3353-3357
    • Jiang, J.1    Anaraki, F.2    Blank, K.J.3    Murasko, D.M.4
  • 36
    • 77957324102 scopus 로고    scopus 로고
    • Enhancement of virus-specific expansion of transgenic CD8 T cells in aged mice by dendritic cells
    • Jiang J., Fisher E., Bennett A.J., Murasko D.M. Enhancement of virus-specific expansion of transgenic CD8 T cells in aged mice by dendritic cells. Mech. Ageing Dev. 2010, 131:580-583.
    • (2010) Mech. Ageing Dev. , vol.131 , pp. 580-583
    • Jiang, J.1    Fisher, E.2    Bennett, A.J.3    Murasko, D.M.4
  • 37
    • 34247136761 scopus 로고    scopus 로고
    • Aging affects initiation and continuation of T cell proliferation
    • Jiang J., Gross D., Elbaum P., Murasko D.M. Aging affects initiation and continuation of T cell proliferation. Mech. Ageing Dev. 2007, 128:332-339.
    • (2007) Mech. Ageing Dev. , vol.128 , pp. 332-339
    • Jiang, J.1    Gross, D.2    Elbaum, P.3    Murasko, D.M.4
  • 38
    • 0029009977 scopus 로고
    • The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing
    • Jiang W., Swiggard W.J., Heufler C., Peng M., Mirza A., Steinman R.M., Nussenzweig M.C. The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing. Nature 1995, 375:151-155.
    • (1995) Nature , vol.375 , pp. 151-155
    • Jiang, W.1    Swiggard, W.J.2    Heufler, C.3    Peng, M.4    Mirza, A.5    Steinman, R.M.6    Nussenzweig, M.C.7
  • 39
    • 0036514779 scopus 로고    scopus 로고
    • Updating the accounts: global mortality of the 1918-1920 "Spanish" influenza pandemic
    • Johnson N.P., Mueller J. Updating the accounts: global mortality of the 1918-1920 "Spanish" influenza pandemic. Bull. Hist. Med. 2002, 76:105-115.
    • (2002) Bull. Hist. Med. , vol.76 , pp. 105-115
    • Johnson, N.P.1    Mueller, J.2
  • 42
    • 1842687400 scopus 로고    scopus 로고
    • Conserved T cell receptor usage in primary and recall responses to an immunodominant influenza virus nucleoprotein epitope
    • Kedzierska K., Turner S.J., Doherty P.C. Conserved T cell receptor usage in primary and recall responses to an immunodominant influenza virus nucleoprotein epitope. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:4942-4947.
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 4942-4947
    • Kedzierska, K.1    Turner, S.J.2    Doherty, P.C.3
  • 43
    • 0023881391 scopus 로고
    • Passive serum antibody causes temporary recovery from influenza virus infection of the nose, trachea and lung of nude mice
    • Kris R.M., Yetter R.A., Cogliano R., Ramphal R., Small P.A. Passive serum antibody causes temporary recovery from influenza virus infection of the nose, trachea and lung of nude mice. Immunology 1988, 63:349-353.
    • (1988) Immunology , vol.63 , pp. 349-353
    • Kris, R.M.1    Yetter, R.A.2    Cogliano, R.3    Ramphal, R.4    Small, P.A.5
  • 44
    • 0025774959 scopus 로고
    • Recognition of disparate HA and NS1 peptides by an H-2Kd-restricted, influenza specific CTL clone
    • Kuwano K., Reyes V.E., Humphreys R.E., Ennis F.A. Recognition of disparate HA and NS1 peptides by an H-2Kd-restricted, influenza specific CTL clone. Mol. Immunol. 1991, 28:1-7.
    • (1991) Mol. Immunol. , vol.28 , pp. 1-7
    • Kuwano, K.1    Reyes, V.E.2    Humphreys, R.E.3    Ennis, F.A.4
  • 46
    • 0035838981 scopus 로고    scopus 로고
    • Regulation of T cell immunity by dendritic cells
    • Lanzavecchia A., Sallusto F. Regulation of T cell immunity by dendritic cells. Cell 2001, 106:263-266.
    • (2001) Cell , vol.106 , pp. 263-266
    • Lanzavecchia, A.1    Sallusto, F.2
  • 48
    • 0028229934 scopus 로고
    • Heterosubtypic immunity to influenza type A virus in mice Effector mechanisms and their longevity
    • Liang S., Mozdzanowska K., Palladino G., Gerhard W. Heterosubtypic immunity to influenza type A virus in mice Effector mechanisms and their longevity. J. Immunol. 1994, 152:1653-1661.
    • (1994) J. Immunol. , vol.152 , pp. 1653-1661
    • Liang, S.1    Mozdzanowska, K.2    Palladino, G.3    Gerhard, W.4
  • 49
    • 0029826636 scopus 로고    scopus 로고
    • Antigen-independent changes in naive CD4 T cells with aging
    • Linton P.J., Haynes L., Klinman N.R., Swain S.L. Antigen-independent changes in naive CD4 T cells with aging. J. Exp. Med. 1996, 184:1891-1900.
    • (1996) J. Exp. Med. , vol.184 , pp. 1891-1900
    • Linton, P.J.1    Haynes, L.2    Klinman, N.R.3    Swain, S.L.4
  • 50
    • 20344374699 scopus 로고    scopus 로고
    • Intrinsic versus environmental influences on T-cell responses in aging
    • Linton P.J., Li S.P., Zhang Y., Bautista B., Huynh Q., Trinh T. Intrinsic versus environmental influences on T-cell responses in aging. Immunol. Rev. 2005, 205:207-219.
    • (2005) Immunol. Rev. , vol.205 , pp. 207-219
    • Linton, P.J.1    Li, S.P.2    Zhang, Y.3    Bautista, B.4    Huynh, Q.5    Trinh, T.6
  • 51
    • 0019412976 scopus 로고
    • Biological properties of an influenza A virus-specific killer T cell clone Inhibition of virus replication in vivo and induction of delayed-type hypersensitivity reactions
    • Lin Y.L., Askonas B.A. Biological properties of an influenza A virus-specific killer T cell clone Inhibition of virus replication in vivo and induction of delayed-type hypersensitivity reactions. J. Exp. Med. 1981, 154:225-234.
    • (1981) J. Exp. Med. , vol.154 , pp. 225-234
    • Lin, Y.L.1    Askonas, B.A.2
  • 52
    • 0021243967 scopus 로고
    • In vivo effector function of influenza virus-specific cytotoxic T lymphocyte clones is highly specific
    • Lukacher A.E., Braciale V.L., Braciale T.J. In vivo effector function of influenza virus-specific cytotoxic T lymphocyte clones is highly specific. J. Exp. Med. 1984, 160:814-826.
    • (1984) J. Exp. Med. , vol.160 , pp. 814-826
    • Lukacher, A.E.1    Braciale, V.L.2    Braciale, T.J.3
  • 54
    • 70349494070 scopus 로고    scopus 로고
    • CD4+ T cells and immunosenescence--a mini-review
    • Maue A.C., Haynes L. CD4+ T cells and immunosenescence--a mini-review. Gerontology 2009, 55:491-495.
    • (2009) Gerontology , vol.55 , pp. 491-495
    • Maue, A.C.1    Haynes, L.2
  • 56
    • 0030579166 scopus 로고    scopus 로고
    • Reversal of age-related deficient influenza virus-specific CTL responses and IFN-gamma production by monophosphoryl lipid A
    • Mbawuike I.N., Acuna C., Caballero D., Pham-Nguyen K., Gilbert B., Petribon P., Harmon M. Reversal of age-related deficient influenza virus-specific CTL responses and IFN-gamma production by monophosphoryl lipid A. Cell. Immunol. 1996, 173:64-78.
    • (1996) Cell. Immunol. , vol.173 , pp. 64-78
    • Mbawuike, I.N.1    Acuna, C.2    Caballero, D.3    Pham-Nguyen, K.4    Gilbert, B.5    Petribon, P.6    Harmon, M.7
  • 57
    • 11844249429 scopus 로고    scopus 로고
    • Crystal structures of murine MHC Class I H-2 D(b) and K(b) molecules in complex with CTL epitopes from influenza A virus: implications for TCR repertoire selection and immunodominance
    • Meijers R., Lai C.C., Yang Y., Liu J.H., Zhong W., Wang J.H., Reinherz E.L. Crystal structures of murine MHC Class I H-2 D(b) and K(b) molecules in complex with CTL epitopes from influenza A virus: implications for TCR repertoire selection and immunodominance. J. Mol. Biol. 2005, 345:1099-1110.
    • (2005) J. Mol. Biol. , vol.345 , pp. 1099-1110
    • Meijers, R.1    Lai, C.C.2    Yang, Y.3    Liu, J.H.4    Zhong, W.5    Wang, J.H.6    Reinherz, E.L.7
  • 58
    • 2242419092 scopus 로고    scopus 로고
    • Direct link between mhc polymorphism T cell avidity, and diversity in immune defense
    • Messaoudi I., Guevara Patino J.A., Dyall R., LeMaoult J., Nikolich-Zugich J. Direct link between mhc polymorphism T cell avidity, and diversity in immune defense. Science 2002, 298:1797-1800.
    • (2002) Science , vol.298 , pp. 1797-1800
    • Messaoudi, I.1    Guevara Patino, J.A.2    Dyall, R.3    LeMaoult, J.4    Nikolich-Zugich, J.5
  • 59
    • 9244265523 scopus 로고    scopus 로고
    • Age-related CD8 T cell clonal expansions constrict CD8 T cell repertoire and have the potential to impair immune defense
    • Messaoudi I., Lemaoult J., Guevara-Patino J.A., Metzner B.M., Nikolich-Zugich J. Age-related CD8 T cell clonal expansions constrict CD8 T cell repertoire and have the potential to impair immune defense. J. Exp. Med. 2004, 200:1347-1358.
    • (2004) J. Exp. Med. , vol.200 , pp. 1347-1358
    • Messaoudi, I.1    Lemaoult, J.2    Guevara-Patino, J.A.3    Metzner, B.M.4    Nikolich-Zugich, J.5
  • 61
    • 0037825764 scopus 로고    scopus 로고
    • Large numbers of dysfunctional CD8+ T lymphocytes bearing receptors for a single dominant CMV epitope in the very old
    • Ouyang Q., Wagner W.M., Wikby A., Walter S., Aubert G., Dodi A.I., Travers P., Pawelec G. Large numbers of dysfunctional CD8+ T lymphocytes bearing receptors for a single dominant CMV epitope in the very old. J. Clin. Immunol. 2003, 23:247-257.
    • (2003) J. Clin. Immunol. , vol.23 , pp. 247-257
    • Ouyang, Q.1    Wagner, W.M.2    Wikby, A.3    Walter, S.4    Aubert, G.5    Dodi, A.I.6    Travers, P.7    Pawelec, G.8
  • 62
    • 84925548986 scopus 로고    scopus 로고
    • The instructive role of dendritic cells on T-cell responses
    • Sallusto F., Lanzavecchia A. The instructive role of dendritic cells on T-cell responses. Arthritis Res. 2002, 3(4 Suppl.):S127-132.
    • (2002) Arthritis Res. , vol.3 , Issue.4 SUPPL.
    • Sallusto, F.1    Lanzavecchia, A.2
  • 63
    • 0035946840 scopus 로고    scopus 로고
    • Severe impairment of primary but not memory responses to influenza viral antigens in aged mice: costimulation in vivo partially reverses impaired primary immune responses
    • Sambhara S., Kurichh A., Miranda R., James O., Underdown B., Klein M., Tartaglia J., Burt D. Severe impairment of primary but not memory responses to influenza viral antigens in aged mice: costimulation in vivo partially reverses impaired primary immune responses. Cell. Immunol. 2001, 210:1-4.
    • (2001) Cell. Immunol. , vol.210 , pp. 1-4
    • Sambhara, S.1    Kurichh, A.2    Miranda, R.3    James, O.4    Underdown, B.5    Klein, M.6    Tartaglia, J.7    Burt, D.8
  • 64
    • 0042905868 scopus 로고    scopus 로고
    • Quantitative studies of CD8+ T-cell responses during microbial infection
    • Serbina N., Pamer E.G. Quantitative studies of CD8+ T-cell responses during microbial infection. Curr. Opin. Immunol. 2003, 15:436-442.
    • (2003) Curr. Opin. Immunol. , vol.15 , pp. 436-442
    • Serbina, N.1    Pamer, E.G.2
  • 65
    • 33845408098 scopus 로고    scopus 로고
    • High accumulation of T regulatory cells prevents the activation of immune responses in aged animals
    • Sharma S., Dominguez A.L., Lustgarten J. High accumulation of T regulatory cells prevents the activation of immune responses in aged animals. J. Immunol. 2006, 177:8348-8355.
    • (2006) J. Immunol. , vol.177 , pp. 8348-8355
    • Sharma, S.1    Dominguez, A.L.2    Lustgarten, J.3
  • 66
    • 0037432787 scopus 로고    scopus 로고
    • Requirement for CD4 T cell help in generating functional CD8 T cell memory
    • Shedlock D.J., Shen H. Requirement for CD4 T cell help in generating functional CD8 T cell memory. Science 2003, 300:337-339.
    • (2003) Science , vol.300 , pp. 337-339
    • Shedlock, D.J.1    Shen, H.2
  • 67
    • 0037432776 scopus 로고    scopus 로고
    • Defective CD8 T cell memory following acute infection without CD4 T cell help
    • Sun J.C., Bevan M.J. Defective CD8 T cell memory following acute infection without CD4 T cell help. Science 2003, 300:339-342.
    • (2003) Science , vol.300 , pp. 339-342
    • Sun, J.C.1    Bevan, M.J.2
  • 68
    • 0037198022 scopus 로고    scopus 로고
    • Age-associated decrease in virus-specific CD8+ T lymphocytes during primary influenza infection
    • Po J.L., Gardner E.M., Anaraki F., Katsikis P.D., Murasko D.M. Age-associated decrease in virus-specific CD8+ T lymphocytes during primary influenza infection. Mech. Ageing Dev. 2002, 123:1167-1181.
    • (2002) Mech. Ageing Dev. , vol.123 , pp. 1167-1181
    • Po, J.L.1    Gardner, E.M.2    Anaraki, F.3    Katsikis, P.D.4    Murasko, D.M.5
  • 70
    • 0027976958 scopus 로고
    • Clonal populations of T cells in normal elderly humans: the T cell equivalent to "benign monoclonal gammapathy"
    • Posnett D.N., Sinha R., Kabak S., Russo C. Clonal populations of T cells in normal elderly humans: the T cell equivalent to "benign monoclonal gammapathy" J. Exp. Med. 1994, 179:609-618.
    • (1994) J. Exp. Med. , vol.179 , pp. 609-618
    • Posnett, D.N.1    Sinha, R.2    Kabak, S.3    Russo, C.4
  • 71
    • 0023200385 scopus 로고
    • Class I MHC molecules rather than other mouse genes dictate influenza epitope recognition by cytotoxic T cells
    • Taylor P.M., Davey J., Howland K., Rothbard J.B., Askonas B.A. Class I MHC molecules rather than other mouse genes dictate influenza epitope recognition by cytotoxic T cells. Immunogenetics 1987, 26:267-272.
    • (1987) Immunogenetics , vol.26 , pp. 267-272
    • Taylor, P.M.1    Davey, J.2    Howland, K.3    Rothbard, J.B.4    Askonas, B.A.5
  • 72
    • 0037425564 scopus 로고    scopus 로고
    • Mortality associated with influenza and respiratory syncytial virus in the United States
    • Thompson W.W., Shay D.K., Weintraub E., Brammer L., Cox N., Anderson L.J., Fukuda K. Mortality associated with influenza and respiratory syncytial virus in the United States. JAMA 2003, 289:179-186.
    • (2003) JAMA , vol.289 , pp. 179-186
    • Thompson, W.W.1    Shay, D.K.2    Weintraub, E.3    Brammer, L.4    Cox, N.5    Anderson, L.J.6    Fukuda, K.7
  • 73
    • 0022483534 scopus 로고
    • The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides
    • Townsend A.R., Rothbard J., Gotch F.M., Bahadur G., Wraith D., McMichael A.J. The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides. Cell 1986, 44:959-968.
    • (1986) Cell , vol.44 , pp. 959-968
    • Townsend, A.R.1    Rothbard, J.2    Gotch, F.M.3    Bahadur, G.4    Wraith, D.5    McMichael, A.J.6
  • 74
    • 79955780015 scopus 로고    scopus 로고
    • Expansion of Regulatory T cells in Aged Mice following Influenza Infection
    • (in press).
    • Williams-Bey, Y., Jiang, J., Murasko, D.M., 2011. Expansion of Regulatory T cells in Aged Mice following Influenza Infection. Mech. Ageing Dev. (in press).
    • (2011) Mech. Ageing Dev.
    • Williams-Bey, Y.1    Jiang, J.2    Murasko, D.M.3
  • 75
    • 41149170727 scopus 로고    scopus 로고
    • Age-associated decline in T cell repertoire diversity leads to holes in the repertoire and impaired immunity to influenza virus
    • Yager E.J., Ahmed M., Lanzer K., Randall T.D., Woodland D.L., Blackman M.A. Age-associated decline in T cell repertoire diversity leads to holes in the repertoire and impaired immunity to influenza virus. J. Exp. Med. 2008, 205:711-723.
    • (2008) J. Exp. Med. , vol.205 , pp. 711-723
    • Yager, E.J.1    Ahmed, M.2    Lanzer, K.3    Randall, T.D.4    Woodland, D.L.5    Blackman, M.A.6
  • 76
    • 0027428401 scopus 로고
    • Antigen processing: a critical factor in rational vaccine design
    • 30, 26-32; discussion
    • Yewdell J.W., Bennink J.R. Antigen processing: a critical factor in rational vaccine design. Semin. Hematol. 1993, 24-33. 30, 26-32; discussion.
    • (1993) Semin. Hematol. , pp. 24-33
    • Yewdell, J.W.1    Bennink, J.R.2
  • 77
    • 17644393143 scopus 로고    scopus 로고
    • Understanding presentation of viral antigens to CD8+ T cells in vivo: the key to rational vaccine design
    • Yewdell J.W., Haeryfar S.M. Understanding presentation of viral antigens to CD8+ T cells in vivo: the key to rational vaccine design. Annu. Rev. Immunol. 2005, 23:651-682.
    • (2005) Annu. Rev. Immunol. , vol.23 , pp. 651-682
    • Yewdell, J.W.1    Haeryfar, S.M.2
  • 78
    • 34249713646 scopus 로고    scopus 로고
    • Changes of CD4+ CD25+ Foxp3+ regulatory T cells in aged Balb/c mice
    • Zhao L., Sun L., Wang H., Ma H., Liu G., Zhao Y. Changes of CD4+ CD25+ Foxp3+ regulatory T cells in aged Balb/c mice. J. Leukoc. Biol. 2007, 81:1386-1394.
    • (2007) J. Leukoc. Biol. , vol.81 , pp. 1386-1394
    • Zhao, L.1    Sun, L.2    Wang, H.3    Ma, H.4    Liu, G.5    Zhao, Y.6
  • 79
    • 38449093221 scopus 로고    scopus 로고
    • Rectification of age-associated deficiency in cytotoxic T cell response to influenza A virus by immunization with immune complexes
    • Zheng B., Zhang Y., He H., Marinova E., Switzer K., Wansley D., Mbawuike I., Han S. Rectification of age-associated deficiency in cytotoxic T cell response to influenza A virus by immunization with immune complexes. J. Immunol. 2007, 179:6153-6159.
    • (2007) J. Immunol. , vol.179 , pp. 6153-6159
    • Zheng, B.1    Zhang, Y.2    He, H.3    Marinova, E.4    Switzer, K.5    Wansley, D.6    Mbawuike, I.7    Han, S.8
  • 80
    • 8344272118 scopus 로고    scopus 로고
    • In vivo selection of a TCR Vbeta repertoire directed against an immunodominant influenza virus CTL epitope
    • Zhong W., Reinherz E.L. In vivo selection of a TCR Vbeta repertoire directed against an immunodominant influenza virus CTL epitope. Int. Immunol. 2004, 16:1549-1559.
    • (2004) Int. Immunol. , vol.16 , pp. 1549-1559
    • Zhong, W.1    Reinherz, E.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.