메뉴 건너뛰기




Volumn 11, Issue 11, 2011, Pages 988-1001

Genetic contributors to frontotemporal lobar degeneration: Beyond monogenic disease

Author keywords

Frontotemporal dementia; Frontotemporal lobar degeneration; Genetics; Polymorphism; Risk factors

Indexed keywords

APOLIPOPROTEIN E; PROGRANULIN; TAU PROTEIN;

EID: 80052282557     PISSN: 13895575     EISSN: 18755607     Source Type: Journal    
DOI: 10.2174/138955711797068517     Document Type: Review
Times cited : (2)

References (158)
  • 2
    • 0034764622 scopus 로고    scopus 로고
    • Work Group on Frontotemporal Dementia and Pick's Disease. Clinical and pathological diagnosis of frontotemporal dementia: Report of the Work Group on Frontotemporal Dementia and Pick's Disease
    • McKhann, G.M.; Albert, M.S.; Grossman, M.; Miller, B.; Dickson, D.; Trojanowski, J.Q. Work Group on Frontotemporal Dementia and Pick's Disease. Clinical and pathological diagnosis of frontotemporal dementia: report of the Work Group on Frontotemporal Dementia and Pick's Disease. Arch. Neurol., 2001, 58, 1803-9.
    • (2001) Arch. Neurol. , vol.58 , pp. 1803-1809
    • McKhann, G.M.1    Albert, M.S.2    Grossman, M.3    Miller, B.4    Dickson, D.5    Trojanowski, J.Q.6
  • 6
    • 34548625293 scopus 로고    scopus 로고
    • Genetic basis of frontotemporal dementia
    • Van Swieten, J.C. Genetic basis of frontotemporal dementia. Lancet. Neurol., 2007, 10, 840-1.
    • (2007) Lancet. Neurol. , vol.10 , pp. 840-841
    • van Swieten, J.C.1
  • 7
    • 0028073692 scopus 로고
    • Localization of disinhibition-dementia-parkinsonismamyotrophy complex to 17q21-22
    • Wilhelmsen, K.C.; Lynch, T.; Pavlou, E.; Higgins, M.; Nygaard, T.G. Localization of disinhibition-dementia-parkinsonismamyotrophy complex to 17q21-22. Am. J. Hum. Genet., 1994, 55, 1159-65.
    • (1994) Am. J. Hum. Genet. , vol.55 , pp. 1159-1165
    • Wilhelmsen, K.C.1    Lynch, T.2    Pavlou, E.3    Higgins, M.4    Nygaard, T.G.5
  • 9
    • 0030757803 scopus 로고    scopus 로고
    • Mapping of a disease locus for familial rapidly progressive frontotemporal dementia to chromosome 17q12-21
    • Froelich, S.; Basun, H.; Forsell, C.; Lilius, L.; Axelman, K.; Andreadis, A.; Lannfelt, L. Mapping of a disease locus for familial rapidly progressive frontotemporal dementia to chromosome 17q12-21. Am. J. Med. Genet., 1997, 74, 380-5.
    • (1997) Am. J. Med. Genet. , vol.74 , pp. 380-385
    • Froelich, S.1    Basun, H.2    Forsell, C.3    Lilius, L.4    Axelman, K.5    Andreadis, A.6    Lannfelt, L.7
  • 14
    • 0030977392 scopus 로고    scopus 로고
    • Frontotemporal dementia and parkinsonism linked to chromosome 17: A consensus conference. Conference Participants
    • Foster, N.L.; Wilhelmsen, K.; Sima, A.A.; Jones, M.Z.; D'Amato, C.J.; Gilman, S. Frontotemporal dementia and parkinsonism linked to chromosome 17: a consensus conference. Conference Participants. Ann. Neurol., 1997, 41, 706-15.
    • (1997) Ann. Neurol. , vol.41 , pp. 706-715
    • Foster, N.L.1    Wilhelmsen, K.2    Sima, A.A.3    Jones, M.Z.4    D'Amato, C.J.5    Gilman, S.6
  • 18
    • 0024387161 scopus 로고
    • Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: Differential expression of tau protein mRNAs in human brain
    • Goedert, M.; Spillantini, M.G.; Potier, M.C.; Ulrich, J.; Crowther, R.A. Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain. EMBO J., 1989, 8, 393-9.
    • (1989) EMBO J , vol.8 , pp. 393-399
    • Goedert, M.1    Spillantini, M.G.2    Potier, M.C.3    Ulrich, J.4    Crowther, R.A.5
  • 26
    • 39749187585 scopus 로고    scopus 로고
    • Frequency and clinical characteristics of progranulin mutation carriers in the Manchester frontotemporal lobar degeneration cohort: Comparison with patients with MAPT and no known mutations
    • Pickering-Brown, S.M.; Rollinson, S.; Du Plessis, D.; Morrison, K.E.; Varma, A.; Richardson, A.M.T; Neary, D.; Snowden, J.S.; Mann, D.M.A. Frequency and clinical characteristics of progranulin mutation carriers in the Manchester frontotemporal lobar degeneration cohort: comparison with patients with MAPT and no known mutations. Brain, 2008, 131, 721-731.
    • (2008) Brain , vol.131 , pp. 721-731
    • Pickering-Brown, S.M.1    Rollinson, S.2    du Plessis, D.3    Morrison, K.E.4    Varma, A.5    Richardson, A.M.T.6    Neary, D.7    Snowden, J.S.8    Mann, D.M.A.9
  • 39
    • 57449097370 scopus 로고    scopus 로고
    • Low prevalence of progranulin mutations in Finnish patients with frontotemporal lobar degeneration
    • Krüger, J.; Kaivorinne, A.L.; Udd, B.; Majamaa, K.; Remes, A.M. Low prevalence of progranulin mutations in Finnish patients with frontotemporal lobar degeneration. Eur. J. Neurol., 2009, 16, 27-30.
    • (2009) Eur. J. Neurol. , vol.16 , pp. 27-30
    • Krüger, J.1    Kaivorinne, A.L.2    Udd, B.3    Majamaa, K.4    Remes, A.M.5
  • 44
    • 42249085980 scopus 로고    scopus 로고
    • Refining frontotemporal dementia with parkinsonism linked to chromosome 17: Introducing FTDP-17 (MAPT) and FTDP-17 (PGRN)
    • Boeve, B.F.; Hutton, M. Refining frontotemporal dementia with parkinsonism linked to chromosome 17: introducing FTDP-17 (MAPT) and FTDP-17 (PGRN). Arch. Neurol., 2008, 65, 460-4.
    • (2008) Arch. Neurol. , vol.65 , pp. 460-464
    • Boeve, B.F.1    Hutton, M.2
  • 45
    • 41249089087 scopus 로고    scopus 로고
    • Loss of progranulin function in frontotemporal lobar degeneration
    • Cruts, M.; Van Broeckhoven, C. Loss of progranulin function in frontotemporal lobar degeneration. Trends Genet., 2008, 24, 186-94.
    • (2008) Trends Genet , vol.24 , pp. 186-194
    • Cruts, M.1    van Broeckhoven, C.2
  • 46
    • 56749171877 scopus 로고    scopus 로고
    • Granulin mutations associated with frontotemporal lobar degeneration and related disorders: An update
    • Gijselinck, I.; Van Broeckhoven, C.; Cruts, M. Granulin mutations associated with frontotemporal lobar degeneration and related disorders: an update. Hum. Mutat., 2008, 29, 1373-86.
    • (2008) Hum. Mutat. , vol.29 , pp. 1373-1386
    • Gijselinck, I.1    van Broeckhoven, C.2    Cruts, M.3
  • 50
    • 1842483843 scopus 로고    scopus 로고
    • Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein
    • Watts, G.D.; Wymer, J.; Kovach, M.J.; Mehta, S.G.; Mumm, S.; Darvish, D.; Pestronk, A.; Whyte, M.P.; Kimonis, V.E. Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein. Nat. Genet., 2004, 36, 377-81.
    • (2004) Nat. Genet. , vol.36 , pp. 377-381
    • Watts, G.D.1    Wymer, J.2    Kovach, M.J.3    Mehta, S.G.4    Mumm, S.5    Darvish, D.6    Pestronk, A.7    Whyte, M.P.8    Kimonis, V.E.9
  • 64
    • 0037403561 scopus 로고    scopus 로고
    • Tau haplotype frequency in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
    • Hughes, A.; Mann, D.; Pickering-Brown, S. Tau haplotype frequency in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Exp. Neurol., 2003, 181, 12-6.
    • (2003) Exp. Neurol. , vol.181 , pp. 12-16
    • Hughes, A.1    Mann, D.2    Pickering-Brown, S.3
  • 74
    • 77449111778 scopus 로고    scopus 로고
    • Common variant in GRN is a genetic risk factor for hippocampal sclerosis in the elderly
    • Dickson, D.W.; Baker, M.; Rademakers, R. Common variant in GRN is a genetic risk factor for hippocampal sclerosis in the elderly. Neurodegener. Dis., 2010, 7, 170-4.
    • (2010) Neurodegener. Dis. , vol.7 , pp. 170-174
    • Dickson, D.W.1    Baker, M.2    Rademakers, R.3
  • 77
    • 70449564311 scopus 로고    scopus 로고
    • Variation at GRN 3'-UTR rs5848 is not associated with a risk of frontotemporal lobar degeneration in Dutch population
    • Simón-Sánchez, J.; Seelaar, H.; Bochdanovits, Z.; Deeg, D.J.; van Swieten, J.C.; Heutink, P. Variation at GRN 3'-UTR rs5848 is not associated with a risk of frontotemporal lobar degeneration in Dutch population. PLoS One, 2009, 4, e7494.
    • (2009) PLoS One , vol.4
    • Simón-Sánchez, J.1    Seelaar, H.2    Bochdanovits, Z.3    Deeg, D.J.4    van Swieten, J.C.5    Heutink, P.6
  • 78
    • 77955544847 scopus 로고    scopus 로고
    • Genetics and biology of Alzheimer's disease and frontotemporal lobar degeneration
    • Galimberti, D.; Scarpini, E. Genetics and biology of Alzheimer's disease and frontotemporal lobar degeneration. Int. J. Exp. Med., 2010, 15, 129-43
    • (2010) Int. J. Exp. Med. , vol.15 , pp. 129-143
    • Galimberti, D.1    Scarpini, E.2
  • 82
    • 80052280407 scopus 로고    scopus 로고
    • The French Research Network on FTD and FTD/MND. CHMP2B mutations are rare in French families with frontotemporal lobar degeneration
    • Ghanim, M.; Guillot-Noel, L.; Pasquier, F.; Jornea, L.; Deramecourt, V.; Dubois, B.; Le Ber, I.; Brice, A. The French Research Network on FTD and FTD/MND. CHMP2B mutations are rare in French families with frontotemporal lobar degeneration. J. Neurol., 2010.
    • (2010) J. Neurol.
    • Ghanim, M.1    Guillot-Noel, L.2    Pasquier, F.3    Jornea, L.4    Deramecourt, V.5    Dubois, B.6    Le Ber, I.7    Brice, A.8
  • 83
    • 0035115847 scopus 로고    scopus 로고
    • Two distal downstream enhancers direct expression of the human apolipoprotein E gene to astrocytes in the brain
    • Grehan, S.; Tse, E.; Taylor, J.M. Two distal downstream enhancers direct expression of the human apolipoprotein E gene to astrocytes in the brain. J. Neurosci., 2001, 21, 812-22.
    • (2001) J. Neurosci. , vol.21 , pp. 812-822
    • Grehan, S.1    Tse, E.2    Taylor, J.M.3
  • 84
    • 0023280054 scopus 로고
    • Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B, E (LDL) receptors in the brain
    • Pitas, R.E.; Boyles, J.K.; Lee, S.H.; Hui, D.; Weisgraber, K.H. Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B, E (LDL) receptors in the brain. J. Biol. Chem., 1987, 262, 14352-60.
    • (1987) J. Biol. Chem. , vol.262 , pp. 14352-14360
    • Pitas, R.E.1    Boyles, J.K.2    Lee, S.H.3    Hui, D.4    Weisgraber, K.H.5
  • 85
    • 33645808672 scopus 로고    scopus 로고
    • Apolipoprotein E4: A causative factor and therapeutic target in neuropathology, including Alzheimer's disease
    • Mahley, R.W.; Weisgraber, K.H.; Huang, Y. Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's disease. Proc. Natl. Acad. Sci. USA., 2006, 103, 5644-51.
    • (2006) Proc. Natl. Acad. Sci. USA. , vol.103 , pp. 5644-5651
    • Mahley, R.W.1    Weisgraber, K.H.2    Huang, Y.3
  • 91
    • 0035072923 scopus 로고    scopus 로고
    • Clinic-based cases with frontotemporal lobar degenerationshow increased cerebrospinal fluid tau and high apolipoprotein E epsilon4 frequency, but no tau gene mutations
    • Fabre, S.F.; Forsell, C.; Viitanen, M.; Sjögren, M.; Wallin, A.; Blennow, K.; Blomberg, M.; Andersen, C.; Wahlund, L.O.; Lannfelt, L. Clinic-based cases with frontotemporal lobar degenerationshow increased cerebrospinal fluid tau and high apolipoprotein E epsilon4 frequency, but no tau gene mutations. Exp. Neurol., 2001, 168, 413-8.
    • (2001) Exp. Neurol. , vol.168 , pp. 413-418
    • Fabre, S.F.1    Forsell, C.2    Viitanen, M.3    Sjögren, M.4    Wallin, A.5    Blennow, K.6    Blomberg, M.7    Andersen, C.8    Wahlund, L.O.9    Lannfelt, L.10
  • 96
    • 0035947446 scopus 로고    scopus 로고
    • Amyloid beta protein deposition in patients with frontotemporal lobar degeneration: Relationship to age and apolipoprotein E genotype
    • Mann, D.M.; McDonagh, A.M.; Pickering-Brown, S.M.; Kowa, H.; Iwatsubo, T. Amyloid beta protein deposition in patients with frontotemporal lobar degeneration: relationship to age and apolipoprotein E genotype. Neurosci. Lett., 2001, 304, 161-4.
    • (2001) Neurosci. Lett. , vol.304 , pp. 161-164
    • Mann, D.M.1    McDonagh, A.M.2    Pickering-Brown, S.M.3    Kowa, H.4    Iwatsubo, T.5
  • 101
    • 0030610527 scopus 로고    scopus 로고
    • The apolipoprotein E epsilon4 allele frequency is normal in frontotemporal dementia, but correlates with age at onset of disease
    • Minthon, L.; Hesse, C.; Sjogren, M.; Englund, E.; Gustafson, L.; Blennow, K. The apolipoprotein E epsilon4 allele frequency is normal in frontotemporal dementia, but correlates with age at onset of disease. Neurosci. Lett., 1997, 226, 65-67.
    • (1997) Neurosci. Lett. , vol.226 , pp. 65-67
    • Minthon, L.1    Hesse, C.2    Sjogren, M.3    Englund, E.4    Gustafson, L.5    Blennow, K.6
  • 107
    • 0242669211 scopus 로고    scopus 로고
    • Neuronal and glial inclusions in frontotemporal dementia with or without motor neuron disease are immunopositive for p62
    • Arai, T.; Nonaka, T.; Hasegawa, M.; Akiyama, H.; Yoshida, M.; Hashizume, Y.; Tsuchiya, K.; Oda, T.; Ikeda, K. Neuronal and glial inclusions in frontotemporal dementia with or without motor neuron disease are immunopositive for p62. Neurosci. Lett., 2003, 342, 41-44.
    • (2003) Neurosci. Lett. , vol.342 , pp. 41-44
    • Arai, T.1    Nonaka, T.2    Hasegawa, M.3    Akiyama, H.4    Yoshida, M.5    Hashizume, Y.6    Tsuchiya, K.7    Oda, T.8    Ikeda, K.9
  • 108
    • 0033016291 scopus 로고    scopus 로고
    • The ubiquitin-proteasome pathway and pathogenesis of human diseases. Annu
    • Schwartz, A.L.; Ciechanover, A. The ubiquitin-proteasome pathway and pathogenesis of human diseases. Annu. Rev. Med., 1999, 50, 57-74.
    • (1999) Rev. Med. , vol.50 , pp. 57-74
    • Schwartz, A.L.1    Ciechanover, A.2
  • 109
    • 2942708228 scopus 로고    scopus 로고
    • Mechanism of neurodegenerative disease: Role of the ubiquitin proteasome system
    • Petrucelli, L.; Dawson, T.M. Mechanism of neurodegenerative disease: role of the ubiquitin proteasome system. Ann. Med., 2004, 36, 315-320.
    • (2004) Ann. Med. , vol.36 , pp. 315-320
    • Petrucelli, L.1    Dawson, T.M.2
  • 112
    • 21744455599 scopus 로고    scopus 로고
    • The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae
    • Kurz, T.; Ö zlü, N.; Rudolf, F. The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae. Nature., 2005, 435, 1257-1261.
    • (2005) Nature , vol.435 , pp. 1257-1261
    • Kurz, T.1    Ö zlü, N.2    Rudolf, F.3
  • 114
    • 0034916581 scopus 로고    scopus 로고
    • Prion diseases of humans and animals: Their causes and molecular basis
    • [Collinge, J. Prion diseases of humans and animals: their causes and molecular basis. Annu. Rev. Neurosci., 2001, 24, 519-550.
    • (2001) Annu. Rev. Neurosci. , vol.24 , pp. 519-550
    • Collinge, J.1
  • 115
    • 0036459944 scopus 로고    scopus 로고
    • Mutations of the prion protein gene phenotypic spectrum
    • Kovacs, G.G.; Trabattoni, G.; Hainfellner, J.A. Mutations of the prion protein gene phenotypic spectrum. J. Neurol., 2002, 249, 1567-1582.
    • (2002) J. Neurol. , vol.249 , pp. 1567-1582
    • Kovacs, G.G.1    Trabattoni, G.2    Hainfellner, J.A.3
  • 117
    • 0035914410 scopus 로고    scopus 로고
    • Prion protein protects human neurons against Bax-mediated apoptosis
    • Bounhar, Y.; Zhang, Y.; Goodyer, C.G.; LeBlanc, A. Prion protein protects human neurons against Bax-mediated apoptosis. J. Biol. Chem., 2001, 276, 39145-39149.
    • (2001) J. Biol. Chem. , vol.276 , pp. 39145-39149
    • Bounhar, Y.1    Zhang, Y.2    Goodyer, C.G.3    Leblanc, A.4
  • 119
    • 2342667384 scopus 로고    scopus 로고
    • New roles for VEGF in nervous tissue-- beyond blood vessels
    • Rosenstein, J.M.; Krum J.M. New roles for VEGF in nervous tissue-- beyond blood vessels. Exp. Neurol., 2004, 187, 246-53.
    • (2004) Exp. Neurol. , vol.187 , pp. 246-253
    • Rosenstein, J.M.1    Krum, J.M.2
  • 121
    • 0036445830 scopus 로고    scopus 로고
    • Vascular and neuronal effects of VEGF in the nervous system: Implications for neurological disorders
    • Carmeliet, P.; Storkebaum, E. Vascular and neuronal effects of VEGF in the nervous system: implications for neurological disorders. Semin. Cell. Dev. Biol., 2002, 13, 39-53.
    • (2002) Semin. Cell. Dev. Biol. , vol.13 , pp. 39-53
    • Carmeliet, P.1    Storkebaum, E.2
  • 123
    • 85081150413 scopus 로고    scopus 로고
    • Haplotype analysis in VEGF gene and increate risk of Alzheimer's Disease
    • Del Bo, R.; Scarlato, M.; Martinelli-Boneschi, F. Haplotype analysis in VEGF gene and increate risk of Alzheimer's Disease. Ann. Neurol., 2005, 58, 488-9.
    • (2005) Ann. Neurol. , vol.58 , pp. 488-489
    • Del Bo, R.1    Scarlato, M.2    Martinelli-Boneschi, F.3
  • 128
    • 0032032658 scopus 로고    scopus 로고
    • nNOS expressing neurons in the entorhinal cortex and hippocampus are affected in patients with Alzheimer's disease
    • Thorns, V.; Hansen, L.; Masliah, E. nNOS expressing neurons in the entorhinal cortex and hippocampus are affected in patients with Alzheimer's disease. Experimental Neurology, 1998, 15, 14-20.
    • (1998) Experimental Neurology , vol.15 , pp. 14-20
    • Thorns, V.1    Hansen, L.2    Masliah, E.3
  • 131
    • 0037331863 scopus 로고    scopus 로고
    • Functional characterization of Glu298Asp mutant human endothelial nitric oxide synthase purified from a yeast expression system
    • Golser, R.; Gorren, A.C.F.; Mayer, B.; Schmidt, K. Functional characterization of Glu298Asp mutant human endothelial nitric oxide synthase purified from a yeast expression system. Nitric. Oxide., 2003, 8, 7-14.
    • (2003) Nitric. Oxide. , vol.8 , pp. 7-14
    • Golser, R.1    Gorren, A.C.F.2    Mayer, B.3    Schmidt, K.4
  • 133
    • 0033532605 scopus 로고    scopus 로고
    • A novel polymorphism in the MCP-1 gene regulatory region that influences MCP-1 expression
    • Rovin, B.H.; Lu, L.; Saxena, R. A novel polymorphism in the MCP-1 gene regulatory region that influences MCP-1 expression. Biochem. Biophys. Res. Commun., 1999, 259, 344-8.
    • (1999) Biochem. Biophys. Res. Commun. , vol.259 , pp. 344-348
    • Rovin, B.H.1    Lu, L.2    Saxena, R.3
  • 135
    • 63449102727 scopus 로고    scopus 로고
    • FOXP2 as a molecular window into speech and language
    • Fisher, S.E.; Scharff, C. FOXP2 as a molecular window into speech and language. Trends Genet., 2009, 25, 166-77.
    • (2009) Trends Genet , vol.25 , pp. 166-177
    • Fisher, S.E.1    Scharff, C.2
  • 136
    • 0035807360 scopus 로고    scopus 로고
    • A forkheaddomain gene is mutated in a severe speech and language disorder
    • Lai, C.S.; Fisher, S.E.; Hurst, J.A.; Vargha-Khadem, F.; Monaco, A.P. A forkheaddomain gene is mutated in a severe speech and language disorder. Nature, 2001, 413, 519-523.
    • (2001) Nature , vol.413 , pp. 519-523
    • Lai, C.S.1    Fisher, S.E.2    Hurst, J.A.3    Vargha-Khadem, F.4    Monaco, A.P.5
  • 142
    • 0035901697 scopus 로고    scopus 로고
    • Increased risk for frontotemporal dementia through interaction between tau polymorphisms and apolipoprotein
    • Ingelson, M.; Fabre, S.F.; Lilius, L. Increased risk for frontotemporal dementia through interaction between tau polymorphisms and apolipoprotein E epsilon4. Neuroreport., 2001, 12, 905-909.
    • (2001) E Epsilon4. Neuroreport. , vol.12 , pp. 905-909
    • Ingelson, M.1    Fabre, S.F.2    Lilius, L.3
  • 144
    • 0036219387 scopus 로고    scopus 로고
    • Differences in tau and apolipoprotein E polymorphism frequencies in sporadic frontotemporal lobar degeneration syndromes
    • Short, R.A.; Graff-Radford, N.R.; Adamson, J.; Baker, M.; Hutton, M. Differences in tau and apolipoprotein E polymorphism frequencies in sporadic frontotemporal lobar degeneration syndromes. Arch. Neurol., 2002, 59, 611-615.
    • (2002) Arch. Neurol. , vol.59 , pp. 611-615
    • Short, R.A.1    Graff-Radford, N.R.2    Adamson, J.3    Baker, M.4    Hutton, M.5
  • 145
    • 0036042633 scopus 로고    scopus 로고
    • Polymorphisms in the tau gene in sporadic frontotemporal dementia and other neurodegenerative disorders
    • Panegyres, P.K.; Zafiris-Toufexis, K. Polymorphisms in the tau gene in sporadic frontotemporal dementia and other neurodegenerative disorders. Eur. J. Neurol., 2002, 9, 485-489.
    • (2002) Eur. J. Neurol. , vol.9 , pp. 485-489
    • Panegyres, P.K.1    Zafiris-Toufexis, K.2
  • 147
    • 23844537812 scopus 로고    scopus 로고
    • TAU haplotype and the Satohin Q7R gene polymorphism do not influence CSF Tau in Alzheimer's disease and are not associated with frontotemporal dementia or Parkinson's disease
    • Johansson, A.; Zetterberg, H.; Håkansson, A.; Nissbrandt, H.; Blennow, K. TAU haplotype and the Satohin Q7R gene polymorphism do not influence CSF Tau in Alzheimer's disease and are not associated with frontotemporal dementia or Parkinson's disease. Neuro-degenerative diseases, 2005, 2, 28-35.
    • (2005) Neuro-degenerative Diseases , vol.2 , pp. 28-35
    • Johansson, A.1    Zetterberg, H.2    Håkansson, A.3    Nissbrandt, H.4    Blennow, K.5
  • 149
    • 0033625714 scopus 로고    scopus 로고
    • Apolipoprotein E epsilon4 allele has no effect on age at onset or duration of disease in cases of frontotemporal dementia with pickor microvacuolar-type histology
    • Pickering-Brown, S.M.; Owen, F.; Isaacs, A.; Snowden, J.; Varma, A.; Neary, D.; Furlong, R.; Daniel, S.E.; Cairns, N.J.; Mann, D.M. Apolipoprotein E epsilon4 allele has no effect on age at onset or duration of disease in cases of frontotemporal dementia with pickor microvacuolar-type histology. Exp. Neurol., 2000, 163, 452-6.
    • (2000) Exp. Neurol. , vol.163 , pp. 452-456
    • Pickering-Brown, S.M.1    Owen, F.2    Isaacs, A.3    Snowden, J.4    Varma, A.5    Neary, D.6    Furlong, R.7    Daniel, S.E.8    Cairns, N.J.9    Mann, D.M.10
  • 151
    • 0037954361 scopus 로고    scopus 로고
    • Apolipoprotein E epsilon 4 in an autopsy series of various dementing disorders
    • Nielsen, A.S.; Ravid, R.; Kamphorst, W.; Jørgensen, O.S. Apolipoprotein E epsilon 4 in an autopsy series of various dementing disorders. J. Alzheimers Dis., 2003, 5, 119-25.
    • (2003) J. Alzheimers Dis. , vol.5 , pp. 119-125
    • Nielsen, A.S.1    Ravid, R.2    Kamphorst, W.3    Jørgensen, O.S.4
  • 154
    • 70349106433 scopus 로고    scopus 로고
    • Association between BDNF Val66Met polymorphism and Alzheimer disease, dementia with Lewy bodies, and Pick disease
    • Fehér, A.; Juhász, A.; Rimanóczy, A.; Kálmán, J.; Janka, Z. Association between BDNF Val66Met polymorphism and Alzheimer disease, dementia with Lewy bodies, and Pick disease. Alzheimer Dis. Assoc. Disord., 2009, 23, 224-8.
    • (2009) Alzheimer Dis. Assoc. Disord. , vol.23 , pp. 224-228
    • Fehér, A.1    Juhász, A.2    Rimanóczy, A.3    Kálmán, J.4    Janka, Z.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.