Neuroprotective role of PrP c against kainate-induced epileptic seizures and cell death depends on the modulation of JNK3 activation by GluR6/7-PSD-95 binding

Molecular Biology of the Cell

Volumn 22, Issue 17, 2011, Pages 3041-3054

  Carulla, Patricia ^a,b,c   Bribián, Ana ^a,b,c   Rangel, Alejandra ^a,b,c,f   Gavín, Rosalina ^b,c   Ferrer, Isidro ^c,d   Caelles, Carme ^b,e   Del Río, José Antonio ^a,b,c   Llorens, Franc ^a,b,c  

^a INSTITUTE FOR BIOENGINEERING OF CATALONIA IBEC   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

^c CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

^d BELLVITGE BIOMEDICAL RESEARCH INSTITUTE IDIBELL   (Spain)

^e INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

^f NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6,7 DINITRO 2,3 QUINOXALINEDIONE; 6,7,8,9 TETRAHYDRO 5 NITROBENZ[G]INDOLE 2,3 DIONE 3 OXIME; KAINIC ACID; MITOGEN ACTIVATED PROTEIN KINASE 12; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; N METHYL DEXTRO ASPARTIC ACID; POSTSYNAPTIC DENSITY PROTEIN 95; PRION PROTEIN; DLGH4 PROTEIN, MOUSE; GLUK2 KAINATE RECEPTOR; GLUK3 KAINATE RECEPTOR; GUANYLATE KINASE; KAINIC ACID RECEPTOR; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 10; PRNP PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; EXCITOTOXICITY; MOUSE; NERVE CELL EXCITABILITY; NEUROPROTECTION; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SEIZURE; SYNAPTIC TRANSMISSION; ANIMAL; C57BL MOUSE; CELL DEATH; CHEMICALLY INDUCED DISORDER; DOWN REGULATION; DRUG EFFECT; EPILEPSY; GENE EXPRESSION; GENETICS; HIPPOCAMPUS; METABOLISM; MOUSE MUTANT; NERVE CELL; PATHOLOGY; PRIMARY CELL CULTURE; PRION; PROTEIN BINDING;

MUS;

ANIMALS; CELL DEATH; DOWN-REGULATION; ENZYME ACTIVATION; EPILEPSY; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION; GUANYLATE KINASE; HIPPOCAMPUS; KAINIC ACID; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASE 10; NEURONS; PRIMARY CELL CULTURE; PRIONS; PROTEIN BINDING; PRPC PROTEINS; RECEPTORS, KAINIC ACID;

EID: 80052228220     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E11-04-0321     Document Type: Article

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