메뉴 건너뛰기




Volumn 19, Issue 1, 2009, Pages 79-89

GluR6-containing KA receptor mediates the activation of p38 MAP kinase in rat hippocampal CA1 region during brain ischemia injury

Author keywords

Brain ischemia; Glutamate receptor 6 (GluR6); Hippocampus; Mixed lineage kinase 3 (MLK3); p38 MAP kinase

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; GLUTAMATE RECEPTOR 6; KAINIC ACID RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE KINASE 6; MITOGEN ACTIVATED PROTEIN KINASE P38; MIXED LINEAGE KINASE 3; POSTSYNAPTIC DENSITY PROTEIN 95; STRESS ACTIVATED PROTEIN KINASE;

EID: 58149473580     PISSN: 10509631     EISSN: 10981063     Source Type: Journal    
DOI: 10.1002/hipo.20479     Document Type: Article
Times cited : (24)

References (40)
  • 1
    • 0032829387 scopus 로고    scopus 로고
    • Prevention of neuronal apoptosis by phorbol ester-induced activation of protein kinase C: Blockade of p38 mitogen-activated protein kinase
    • Behrens MM, Strasser U, Koh JY, Gwag BJ, Choi DW, 1999. Prevention of neuronal apoptosis by phorbol ester-induced activation of protein kinase C: Blockade of p38 mitogen-activated protein kinase. Neuroscience 94:917-927.
    • (1999) Neuroscience , vol.94 , pp. 917-927
    • Behrens, M.M.1    Strasser, U.2    Koh, J.Y.3    Gwag, B.J.4    Choi, D.W.5
  • 2
    • 33747632142 scopus 로고    scopus 로고
    • MAPK-activated protein kinase 2 deficiency in microglia inhibits proinflammatory mediator release and resultant neurotoxicity. Relevance to neuroinflammation in a transgenic mouse model of Alzheimer disease
    • Culbert AA, Skaper SD, Howlett DR, Evans NA, Facci L, Soden PE, Seymour ZM, Guillot F, Gaestel M, Richardson JC. 2006. MAPK-activated protein kinase 2 deficiency in microglia inhibits proinflammatory mediator release and resultant neurotoxicity. Relevance to neuroinflammation in a transgenic mouse model of Alzheimer disease, J Biol Chem 281:23658-23667.
    • (2006) J Biol Chem , vol.281 , pp. 23658-23667
    • Culbert, A.A.1    Skaper, S.D.2    Howlett, D.R.3    Evans, N.A.4    Facci, L.5    Soden, P.E.6    Seymour, Z.M.7    Guillot, F.8    Gaestel, M.9    Richardson, J.C.10
  • 3
    • 0030712362 scopus 로고    scopus 로고
    • Blockade of p38 mitogen-activated protein kinase pathway inhibits inducible nitricoxide synthase expression in mouse astrocytes
    • Da Silva J, Pierrat B, Mary JL, Lesslauer W. 1997. Blockade of p38 mitogen-activated protein kinase pathway inhibits inducible nitricoxide synthase expression in mouse astrocytes. J Biol Chem 272:28373-28380.
    • (1997) J Biol Chem , vol.272 , pp. 28373-28380
    • Da Silva, J.1    Pierrat, B.2    Mary, J.L.3    Lesslauer, W.4
  • 6
    • 0028340349 scopus 로고
    • Identification and characterization of SPRK, a novel srchomology 3 domain-containing proline-rich kinase with serine/threonine kinase activity
    • Gallo KA, Mark MR, Scadden DT, Wang Z, Gu Q, Godowski PJ. 1994. Identification and characterization of SPRK, a novel srchomology 3 domain-containing proline-rich kinase with serine/threonine kinase activity. J Biol Chem 269:15092-15100.
    • (1994) J Biol Chem , vol.269 , pp. 15092-15100
    • Gallo, K.A.1    Mark, M.R.2    Scadden, D.T.3    Wang, Z.4    Gu, Q.5    Godowski, P.J.6
  • 7
    • 0030044182 scopus 로고    scopus 로고
    • Characterization of the structure and function of a novel MAP kinase kinase (MKK6)
    • Han J, Lee JD, Jiang Y, Li Z, Feng L, Ulevitch RJ. 1996. Characterization of the structure and function of a novel MAP kinase kinase (MKK6). J Biol Chem 271:2886-2891.
    • (1996) J Biol Chem , vol.271 , pp. 2886-2891
    • Han, J.1    Lee, J.D.2    Jiang, Y.3    Li, Z.4    Feng, L.5    Ulevitch, R.J.6
  • 8
    • 0031047962 scopus 로고    scopus 로고
    • Identification and characterization of a predominant isoform of human MKK3
    • Han J, Wang X, Jiang Y, Ulevitch RJ, Lin S. 1997. Identification and characterization of a predominant isoform of human MKK3. FEBS Lett 403:19-22.
    • (1997) FEBS Lett , vol.403 , pp. 19-22
    • Han, J.1    Wang, X.2    Jiang, Y.3    Ulevitch, R.J.4    Lin, S.5
  • 9
    • 0035033952 scopus 로고    scopus 로고
    • Signalling for survival and death in neurones: The role of stress-activated kinases, JNK and p38
    • Harper SJ, LoGrasso P. 2001. Signalling for survival and death in neurones: The role of stress-activated kinases, JNK and p38 Cell Signal 13:299-310.
    • (2001) Cell Signal , vol.13 , pp. 299-310
    • Harper, S.J.1    LoGrasso, P.2
  • 11
    • 0036263403 scopus 로고    scopus 로고
    • Role of mitogen- and stress-activated kinases in ischemic injury
    • Irving EA, Bamford M. 2002. Role of mitogen- and stress-activated kinases in ischemic injury. J Cereb Blood Flow Metab 22:631-647.
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 631-647
    • Irving, E.A.1    Bamford, M.2
  • 12
    • 0030741894 scopus 로고    scopus 로고
    • Activation and involvement of p38 mitogenactivated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells
    • Kawasaki H, Morooka T, Shimohama S, Kimura J, Hirano T, Gotoh Y, Nishida E. 1997. Activation and involvement of p38 mitogenactivated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells. J Biol Chem 272:18518-18521.
    • (1997) J Biol Chem , vol.272 , pp. 18518-18521
    • Kawasaki, H.1    Morooka, T.2    Shimohama, S.3    Kimura, J.4    Hirano, T.5    Gotoh, Y.6    Nishida, E.7
  • 13
    • 3142741044 scopus 로고    scopus 로고
    • Mixed lineage kinase 3 (MLK3)-activated p38 MAP kinase mediates transforming growth factor-β-induced apoptosis in hepatoma cells
    • Kim KY, Kim BC, Xu Z, Kim SJ. 2004. Mixed lineage kinase 3 (MLK3)-activated p38 MAP kinase mediates transforming growth factor-β-induced apoptosis in hepatoma cells. J Biol Chem 279:29478-29484.
    • (2004) J Biol Chem , vol.279 , pp. 29478-29484
    • Kim, K.Y.1    Kim, B.C.2    Xu, Z.3    Kim, S.J.4
  • 15
    • 0035910529 scopus 로고    scopus 로고
    • The kinase activation loop is the key to mixed lineage kinase-3 activation via both autophosphorylation and hematopoietic progenitor kinase 1 phosphorylation
    • Leung IW, Lassam N. 2001. The kinase activation loop is the key to mixed lineage kinase-3 activation via both autophosphorylation and hematopoietic progenitor kinase 1 phosphorylation. J Biol Chem 276:1961-1967.
    • (2001) J Biol Chem , vol.276 , pp. 1961-1967
    • Leung, I.W.1    Lassam, N.2
  • 17
    • 0032473367 scopus 로고    scopus 로고
    • Molecular biology of glutamate receptors in the central nervous system and their role in excitotoxicity, oxidative stress and aging
    • Michaelis EK. 1998. Molecular biology of glutamate receptors in the central nervous system and their role in excitotoxicity, oxidative stress and aging. Prog Neurobiol 54:369-415.
    • (1998) Prog Neurobiol , vol.54 , pp. 369-415
    • Michaelis, E.K.1
  • 18
    • 0033970158 scopus 로고    scopus 로고
    • JNK and p38 stresskinases-degenerative effectors of signal-transduction-cascades in the nervous system
    • Mielke K, Herdegen T. 2000. JNK and p38 stresskinases-degenerative effectors of signal-transduction-cascades in the nervous system. Prog Neurobiol 61:45-60.
    • (2000) Prog Neurobiol , vol.61 , pp. 45-60
    • Mielke, K.1    Herdegen, T.2
  • 20
    • 0032895885 scopus 로고    scopus 로고
    • Induction of apoptosis signal regulating kinase 1 (ASK1) after spinal cord injury in rats; Possible involvement of ASK1-JNK and -p38 pathways in neuronal apoptosis
    • Nakahara S, Yone K, Sakou T, Wada S, Nagamine T, Niiyama T, Ichijo H. 1999. Induction of apoptosis signal regulating kinase 1 (ASK1) after spinal cord injury in rats; Possible involvement of ASK1-JNK and -p38 pathways in neuronal apoptosis. J Neuropathol Exp Neurol 58:442-450.
    • (1999) J Neuropathol Exp Neurol , vol.58 , pp. 442-450
    • Nakahara, S.1    Yone, K.2    Sakou, T.3    Wada, S.4    Nagamine, T.5    Niiyama, T.6    Ichijo, H.7
  • 22
    • 12844273579 scopus 로고    scopus 로고
    • The neuroprotective effects of K252a through inhibiting MLK3/MKK7/JNK3 signaling pathway on ischemic brain injury in rat hippocampal CA1 region
    • Pan J, Zhang QG, Zhang GY. 2005. The neuroprotective effects of K252a through inhibiting MLK3/MKK7/JNK3 signaling pathway on ischemic brain injury in rat hippocampal CA1 region. Neuroscience 131:147-159.
    • (2005) Neuroscience , vol.131 , pp. 147-159
    • Pan, J.1    Zhang, Q.G.2    Zhang, G.Y.3
  • 23
    • 28444432377 scopus 로고    scopus 로고
    • Neuroprotective effects of GluR6 antisense oligodeoxynucleotides on transient brain ischemia/reperfusion-induced neuronal death in rat hippocampal CA1 region
    • Pei DS, Guan QH, Sun YF, Zhang QX, Xu TL, Zhang GY. 2005. Neuroprotective effects of GluR6 antisense oligodeoxynucleotides on transient brain ischemia/reperfusion-induced neuronal death in rat hippocampal CA1 region. J Neurosci Res 82:642-649.
    • (2005) J Neurosci Res , vol.82 , pp. 642-649
    • Pei, D.S.1    Guan, Q.H.2    Sun, Y.F.3    Zhang, Q.X.4    Xu, T.L.5    Zhang, G.Y.6
  • 24
    • 31544459549 scopus 로고    scopus 로고
    • Neuroprotection against ischaemic brain injury by a GluR6-9c peptide containing the TAT protein transduction sequence
    • Pei DS, Wang XT, Liu Y, Sun YF, Guan QH, Wang W, Yan JZ, Zong YY, Xu TL, Zhang GY. 2006. Neuroprotection against ischaemic brain injury by a GluR6-9c peptide containing the TAT protein transduction sequence. Brain 129 (Part 2):465-479.
    • (2006) Brain , vol.129 , Issue.PART 2 , pp. 465-479
    • Pei, D.S.1    Wang, X.T.2    Liu, Y.3    Sun, Y.F.4    Guan, Q.H.5    Wang, W.6    Yan, J.Z.7    Zong, Y.Y.8    Xu, T.L.9    Zhang, G.Y.10
  • 25
    • 0018347695 scopus 로고
    • A new model of bilateral hemispheric ischemia in the unanesthetized rat
    • Pulsinelli WA, Brierley JB. 1979. A new model of bilateral hemispheric ischemia in the unanesthetized rat. Stroke 10:267-272.
    • (1979) Stroke , vol.10 , pp. 267-272
    • Pulsinelli, W.A.1    Brierley, J.B.2
  • 26
    • 0028935270 scopus 로고
    • Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine
    • Raingeaud J, Gupta S, Rogers JS, Dickens M, Han J, Ulevitch RJ, Davis RJ. 1995. Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J Biol Chem 270:7420-7426.
    • (1995) J Biol Chem , vol.270 , pp. 7420-7426
    • Raingeaud, J.1    Gupta, S.2    Rogers, J.S.3    Dickens, M.4    Han, J.5    Ulevitch, R.J.6    Davis, R.J.7
  • 27
    • 0030051528 scopus 로고    scopus 로고
    • MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway
    • Raingeaud J, Whitmarsh AJ, Barrett T, Derijard B, Dans RJ. 1996. MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. Mol Cell Biol 16:1247-1255.
    • (1996) Mol Cell Biol , vol.16 , pp. 1247-1255
    • Raingeaud, J.1    Whitmarsh, A.J.2    Barrett, T.3    Derijard, B.4    Dans, R.J.5
  • 28
    • 0037147130 scopus 로고    scopus 로고
    • K252a and CEP 1347 are neuroprotective compounds that inhibit mixed-lineage kinase-3 and induce activation of Akt and ERK
    • Roux PP, Dorval G, Boudreau M, Angers-Loustau A, Morris SJ, Makkerh J, Barker PA. 2002. K252a and CEP 1347 are neuroprotective compounds that inhibit mixed-lineage kinase-3 and induce activation of Akt and ERK. J Biol Chem 277:49473-49480.
    • (2002) J Biol Chem , vol.277 , pp. 49473-49480
    • Roux, P.P.1    Dorval, G.2    Boudreau, M.3    Angers-Loustau, A.4    Morris, S.J.5    Makkerh, J.6    Barker, P.A.7
  • 29
    • 0035815679 scopus 로고    scopus 로고
    • Kainate receptor activation induces mixed lineage kinase-mediated cellular signaling cascades via post-synaptic density protein 95
    • Savinainen A, Garcia EP, Dorow D, Marshall J, Liu YF. 2001. Kainate receptor activation induces mixed lineage kinase-mediated cellular signaling cascades via post-synaptic density protein 95. J Biol Chem 276:11382-11386.
    • (2001) J Biol Chem , vol.276 , pp. 11382-11386
    • Savinainen, A.1    Garcia, E.P.2    Dorow, D.3    Marshall, J.4    Liu, Y.F.5
  • 30
    • 0027234701 scopus 로고
    • The TINS/TiPS lecture. The molecular biology of mammalian glutamate receptor channels
    • Seeburg PH. 1993. The TINS/TiPS lecture. The molecular biology of mammalian glutamate receptor channels. Trends Neurosci 16:359-365.
    • (1993) Trends Neurosci , vol.16 , pp. 359-365
    • Seeburg, P.H.1
  • 31
    • 0030006618 scopus 로고    scopus 로고
    • Cloning and characterization of MEK6, a novel member of the mitogenactivated protein kinase kinase cascade
    • Stein B, Brady H, Yang MX, Young DB, Barbosa MS. 1996. Cloning and characterization of MEK6, a novel member of the mitogenactivated protein kinase kinase cascade. J Biol Chem 271:11427-11433.
    • (1996) J Biol Chem , vol.271 , pp. 11427-11433
    • Stein, B.1    Brady, H.2    Yang, M.X.3    Young, D.B.4    Barbosa, M.S.5
  • 32
    • 0043163796 scopus 로고    scopus 로고
    • Antioxidant N-acetylcysteine and AMPA/KA receptor antagonist DNQX inhibited mixed lineage kinase-3 activation following cerebral ischemia in rat hippocampus
    • Tian H, Zhang Q, Li H, Zhang G. 2003. Antioxidant N-acetylcysteine and AMPA/KA receptor antagonist DNQX inhibited mixed lineage kinase-3 activation following cerebral ischemia in rat hippocampus. Neurosci Res 47:47-53.
    • (2003) Neurosci Res , vol.47 , pp. 47-53
    • Tian, H.1    Zhang, Q.2    Li, H.3    Zhang, G.4
  • 33
    • 27444434211 scopus 로고    scopus 로고
    • 2-terminal kinase 3 is mediated by the GluR6.PSD-95.MLK3 signaling module following cerebral ischemia in rat hippocampus
    • 2-terminal kinase 3 is mediated by the GluR6.PSD-95.MLK3 signaling module following cerebral ischemia in rat hippocampus. Brain Res 1061:57-66.
    • (2005) Brain Res , vol.1061 , pp. 57-66
    • Tian, H.1    Zhang, Q.G.2    Zhu, G.X.3    Pei, D.S.4    Guan, Q.H.5    Zhang, G.Y.6
  • 35
    • 0028169790 scopus 로고
    • Selective block of recombinant glur6 receptors by NS-102, a novel non-NMDA receptor antagonist
    • Verdoorn TA, Johansen TH, Drejer J, Nielsen EO. 1994. Selective block of recombinant glur6 receptors by NS-102, a novel non-NMDA receptor antagonist. Eur J Pharmacol 269:43-49.
    • (1994) Eur J Pharmacol , vol.269 , pp. 43-49
    • Verdoorn, T.A.1    Johansen, T.H.2    Drejer, J.3    Nielsen, E.O.4
  • 37
    • 0037113928 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase-activated protein (MAPKAP) kinase 2 deficiency protects brain from ischemic injury in mice
    • Wang X, Xu L, Wang H, Young PR, Gaestel M, Feuerstein GZ. 2002. Mitogen-activated protein kinase-activated protein (MAPKAP) kinase 2 deficiency protects brain from ischemic injury in mice. J Biol Chem 277:43968-43972.
    • (2002) J Biol Chem , vol.277 , pp. 43968-43972
    • Wang, X.1    Xu, L.2    Wang, H.3    Young, P.R.4    Gaestel, M.5    Feuerstein, G.Z.6
  • 38
  • 39
    • 21244446243 scopus 로고    scopus 로고
    • Multi-gene gateway clone design for expression of multiple heterologous genes in living cells: Conditional gene expression at near physiological levels
    • Yahata K, Kishine H, Sone T, Sasaki Y, Hotta J, Chesnut JD, Okabe M, Imamoto F. 2005. Multi-gene gateway clone design for expression of multiple heterologous genes in living cells: Conditional gene expression at near physiological levels. J Biotechnol 118:123-134.
    • (2005) J Biotechnol , vol.118 , pp. 123-134
    • Yahata, K.1    Kishine, H.2    Sone, T.3    Sasaki, Y.4    Hotta, J.5    Chesnut, J.D.6    Okabe, M.7    Imamoto, F.8
  • 40
    • 33745112278 scopus 로고    scopus 로고
    • Blockade of the translocation and activation of mitogen-activated protein kinase kinase 4 (MKK4) signaling attenuates neuronal damage during later ischemia-reperfusion
    • Zhang QX, Pei DS, Guan QH, Sun YF, Liu XM, Zhang GY. 2006. Blockade of the translocation and activation of mitogen-activated protein kinase kinase 4 (MKK4) signaling attenuates neuronal damage during later ischemia-reperfusion. J Neurochem 98:170-179.
    • (2006) J Neurochem , vol.98 , pp. 170-179
    • Zhang, Q.X.1    Pei, D.S.2    Guan, Q.H.3    Sun, Y.F.4    Liu, X.M.5    Zhang, G.Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.