Bromophycolide A targets heme crystallization in the human malaria parasite Plasmodium falciparum

ChemMedChem

Volumn 6, Issue 9, 2011, Pages 1572-1577

  Stout, E Paige ^a   Cervantes, Serena ^b   Prudhomme, Jacques ^b   France, Stefan ^a   La Clair, James J ^c   Le Roch, Karine ^b   Kubanek, Julia ^a  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Xenobe Research Institute   (United States)

Author keywords

Antimalarial agents; Confocal imaging; Hemins; Macroalgae; Natural products

Indexed keywords

4 DIMETHYLAMINOPYRIDINE; AMODIAQUINE; ANTIMALARIAL AGENT; BROMOPHYCOLIDE A; ETHYLDIISOPROPYLAMINE; HEMATIN; HYDROXYL GROUP; N' (3 DIMETHYLAMINOPROPYL) N ETHYLCARBODIIMIDE; N,N DIMETHYLFORMAMIDE; QUININE; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; CALLOPHYCUS SERRATUS; CELL CYCLE; CELL PROLIFERATION; CIRCULAR DICHROISM; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CRYSTALLIZATION; DRUG STRUCTURE; DRUG TARGETING; HUMAN; IC 50; IN VITRO STUDY; MACROALGA; MALARIA FALCIPARUM; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIMALARIALS; CRYSTALLIZATION; DITERPENES; HEME; HUMANS; MALARIA, FALCIPARUM; PLASMODIUM FALCIPARUM; SEAWEED;

EID: 80052089004     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201100252     Document Type: Article

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