Orally administered glucosylceramide improves the skin barrier function by upregulating genes associated with the tight junction and cornified envelope formation

Bioscience, Biotechnology and Biochemistry

Volumn 75, Issue 8, 2011, Pages 1516-1523

  Ideta, Ritsuro ^a   Sakuta, Tomohiro ^a   Nakano, Yusuke ^a   Uchiyama, Taro ^a  

^a SHISEIDO RESEARCH CENTER   (Japan)

Author keywords

Cornified envelope; Glucosylceramide; Skin barrier; Sphingoid base; Tight junction

Indexed keywords

CORNIFIED ENVELOPE; ELECTRICAL RESISTANCES; GLUCOSYLCERAMIDE; KERATINOCYTES; MOLECULAR MECHANISM; MOUSE SKIN; MRNA EXPRESSION; ORAL ADMINISTRATION; PHYTOSPHINGOSINES; SKIN BARRIER FUNCTIONS; SPHINGOID BASE; SPHINGOSINE; TIGHT JUNCTIONS; TRANSEPIDERMAL WATER LOSS;

MAMMALS; METABOLISM; METABOLITES;

GENE EXPRESSION;

DODECYL SULFATE SODIUM; DRUG DERIVATIVE; GLUCOSYLCERAMIDE; PHYTOSPHINGOSINE; RNA; SPHINGOSINE;

ANIMAL; ARTICLE; BIOSYNTHESIS; CYTOLOGY; DRUG EFFECT; EPIDERMIS; EPITHELIUM CELL; GENE EXPRESSION PROFILING; GENETICS; HAIRLESS MOUSE; IMPEDANCE; KERATINOCYTE; MALE; METABOLISM; MOUSE; ORAL DRUG ADMINISTRATION; TIGHT JUNCTION; TOPICAL DRUG ADMINISTRATION; UPREGULATION;

ADMINISTRATION, ORAL; ADMINISTRATION, TOPICAL; ANIMALS; ELECTRIC IMPEDANCE; EPIDERMIS; EPITHELIAL CELLS; GENE EXPRESSION PROFILING; GLUCOSYLCERAMIDES; KERATINOCYTES; MALE; MICE; MICE, HAIRLESS; RNA; SODIUM DODECYL SULFATE; SPHINGOSINE; TIGHT JUNCTIONS; UP-REGULATION;

SPHINGOIDEA;

EID: 80052011658     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.110215     Document Type: Article

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