Calmodulin kinase II accelerates L-type Ca2+ current recovery from inactivation and compensates for the direct inhibitory effect of [Ca2+]i in rat ventricular myocytes

Journal of Physiology

Volumn 574, Issue 2, 2006, Pages 509-518

  Guo, Jiqing ^a   Duff, Henry J ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL L TYPE; CALCIUM ION; EGTAZIC ACID; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; PROTEIN KINASE (CALCIUM,CALMODULIN) II; THAPSIGARGIN; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II;

ADAPTATION; ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CONTROLLED STUDY; ENZYME ACTIVITY; HEART MUSCLE CELL; HEART RATE; HEART VENTRICLE; MALE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; ADULT; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; ENZYME ACTIVATION; PERFORATED PATCH CLAMP; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM;

ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM; CALCIUM CHANNELS, L-TYPE; CHELATING AGENTS; EGTAZIC ACID; ENZYME ACTIVATION; ENZYME INHIBITORS; FEEDBACK, BIOCHEMICAL; MALE; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; PEPTIDES; RATS; RATS, INBRED STRAINS; SARCOPLASMIC RETICULUM; THAPSIGARGIN;

EID: 33745751387     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2006.109199     Document Type: Article

References (30)

1. 2+ channel inactivation in controlling heart excitation. Proc Natl Acad Sci U S A 99, 17185-17190.
2. Anderson ME (2004). Calmodulin kinase and L-type calcium channels; a recipe for arrhythmias?Trends Cardiovasc Med 14, 152-161.
3. Bers DM (2001). Control of cardiac contraction by ER and sarcolemmal Ca flux. Excitation-Contraction Coupling and Cardiac Contractile Force, 2nd edition. ed. Bers DM, pp. 3-39. Kluwer Academic Publishers, Dordrecht.
4. 2+ buffers. Methods Cell Biol 40, 3-29.
5. 2+ oscillations. Science 279, 227-230.
6. 2+ release by the sarcoplasmic reticulum. J Mol Cell Cardiol 31, 1783-1793.
7. Dzhura I, Wu Y, Colbran RJ, Balser JR & Anderson ME (2000). Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels. Nat Cell Biol 2, 173-177.
8. 2+ channels. J Physiol 545, 399-406.
9. Fan JS & Palade P (1998). Perforated patch recording with b-escin. Pflugers Arch 436, 1021-1023.
10. 2+ stores depletion, is mediated by arachidonic acid. Cell Calcium 24, 293-304.
11. Ca-L is the major determinant of use-dependent facilitation in rat cardiomyocytes. J Physiol 547, 797-805.
12. 2+ signals for facilitation. J Cell Biol 171, 537-547.
13. Ishida A, Kameshita I, Okuno S, Kitani T & Fujisawa H (1995). A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II. Biochem Biophys Res Commun 212, 806-812.
14. 2+ channels. J Biol Chem 281, 4691-4698.
15. 2+ - and voltage-dependent inactivation of the expressed L-type Cav1.2 calcium channel. Arch Biochem Biophys 437, 42-50.
16. 2+ release. Circ Res 92, 904-911.
17. 2+] at the mouth of a calcium channel. J Neurosci 17, 6961-6973.
18. 2+ release channel (ryanodine receptor) in cardiac sarcoplasmic reticulum. Arch Biochem Biophys 333, 368-376.
19. 2+-dependent inactivation of L-type calcium channels. Neuron 22, 549-558.
20. 2+ channels. J Biol Chem 276, 30794-30802.
21. 2+ channels in rat heart. J Physiol 536, 387-396.
22. Tong CW, Gaffin RD, Zawieja DC & Muthuchamy M (2004). Roles of phosphorylation of myosin binding protein-C and troponin I in mouse cardiac muscle twitch dynamics. J Physiol 558, 927-941.
23. Tsien RY (1980). New calcium indicators and buffers with high selectivity against magnesium and protons: Design, synthesis, and properties of prototype structures. Biochemistry 19, 2396-2404.
24. 2+/ calmodulin-dependent protein kinase II activation. Circ Res 87, 760-767.
25. 2+ current in rabbit ventricular myocytes by a common mechanism. J Physiol 535, 679-687.
26. 2+ current: A cellular mechanism for long Q-T arrhythmias. Am J Physiol 276, H2168-H2178.
27. 2+/calmodulin-dependent kinase II activity by membrane voltage and by calcium influx. Proc Natl Acad Sci U S A 91, 9659-9663.
28. Yuan W & Bers DM (1994). Ca-dependent facilitation of cardiac Ca current is due to Ca-calmodulin-dependent protein kinase. Am J Physiol 267, H982-H993.
29. Zuhlke RD, Pitt GS, Deisseroth K, Tsien RW & Reuter H (1999). Calmodulin supports both inactivation and facilitation of L-type calcium channels. Nature 399, 159-162.
30. 2+ channels both depend on specific amino acid residues in a consensus calmodulin-binding motif in the (alpha) 1C subunit. J Biol Chem 275, 21121-21129.