Calmodulin kinase II inhibition shortens action potential duration by upregulation of K+ currents

Circulation Research

Volumn 99, Issue 10, 2006, Pages 1092-1099

  Li, Jingdong ^a,b   Marionneau, Céline ^c   Zhang, Rong ^d   Shah, Vaibhavi ^a   Hell, Johannes W ^a   Nerbonne, Jeanne M ^c   Anderson, Mark E ^a,e  

^a UNIVERSITY OF IOWA   (United States)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d STANFORD UNIVERSITY   (United States)

^e University of Iowa ^*  (United States)

Author keywords

Ca2+ calmodulin dependent protein kinase II; Calcium signaling; Repolarization

Indexed keywords

CALCIUM CHANNEL L TYPE; CYCLIC AMP DEPENDENT PROTEIN KINASE; INWARDLY RECTIFYING POTASSIUM CHANNEL; PHOSPHOLAMBAN; PROTEIN KINASE (CALCIUM,CALMODULIN) II;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM CELL LEVEL; CALCIUM CURRENT; CALCIUM SIGNALING; CONTROLLED STUDY; DIALYSIS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; FEMALE; HEART MUSCLE CELL; HEART MUSCLE POTENTIAL; HEART REPOLARIZATION; INTRACELLULAR RECORDING; MALE; MOUSE; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; QT INTERVAL; SIGNAL TRANSDUCTION; TRANSGENICS; UPREGULATION; VOLTAGE CLAMP; WHOLE CELL;

ACTION POTENTIALS; ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM; CALCIUM CHANNELS, L-TYPE; CALCIUM-BINDING PROTEINS; CARRIER PROTEINS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ELECTROCARDIOGRAPHY; HEART VENTRICLES; MICE; MYOCYTES, CARDIAC; PHOSPHORYLATION; POTASSIUM CHANNELS; SARCOPLASMIC RETICULUM; UP-REGULATION;

EID: 33750915091     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000249369.71709.5c     Document Type: Article

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