메뉴 건너뛰기




Volumn 16, Issue 3, 2011, Pages 493-505

Emerging drugs to treat juvenile idiopathic arthritis

Author keywords

biological agents; joint damage; juvenile idiopathic arthritis; small molecules

Indexed keywords

ABATACEPT; ADALIMUMAB; ARKALIST; CANAKINUMAB; ETANERCEPT; INFLIXIMAB; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; PROTEIN TYROSINE KINASE INHIBITOR; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; RILONACET; TOCILIZUMAB; TUMOR NECROSIS FACTOR INHIBITOR; UNCLASSIFIED DRUG;

EID: 80051975943     PISSN: 14728214     EISSN: None     Source Type: Journal    
DOI: 10.1517/14728214.2011.581662     Document Type: Review
Times cited : (24)

References (116)
  • 1
    • 33847287323 scopus 로고    scopus 로고
    • Juvenile idiopathic arthritis
    • A clinical review on juvenile idiopathic arthritis
    • Ravelli A, Martini A. Juvenile idiopathic arthritis. Lancet 2007;369:767-78 A clinical review on juvenile idiopathic arthritis.
    • (2007) Lancet , vol.369 , pp. 767-778
    • Ravelli, A.1    Martini, A.2
  • 2
    • 80051998548 scopus 로고    scopus 로고
    • Juvenile idiopathic arthritis: New perspectives on classification pathogenesis and treatment
    • in press A clinical and pathogenetic review on juvenile idiopathic arthritis
    • Prakken B, Albani S, Martini A. Juvenile idiopathic arthritis: New perspectives on classification, pathogenesis and treatment. Lancet 2011;in press A clinical and pathogenetic review on juvenile idiopathic arthritis.
    • (2011) Lancet
    • Prakken, B.1    Albani, S.2    Martini, A.3
  • 3
    • 0031720762 scopus 로고    scopus 로고
    • Revision of the proposed classification criteria for juvenile idiopathic arthritides: Durban, 1997
    • Petty RE, Southwood TR, Baum J, et al. Revision of the proposed classification criteria for juvenile idiopathic arthritides: Durban, 1997. J Rheumatol 1998;25:1991-4
    • (1998) J Rheumatol , vol.25 , pp. 1991-1994
    • Petty, R.E.1    Southwood, T.R.2    Baum, J.3
  • 4
    • 10744230484 scopus 로고    scopus 로고
    • International league of associations for rheumatology classification of juvenile idiopathic arthritis: Second revision, Edmonton, 2001
    • Petty RE, Southwood TR, Manners P, et al. International league of associations for rheumatology classification of juvenile idiopathic arthritis: Second revision, Edmonton, 2001. J Rheumatol 2004;31:390-2
    • (2004) J Rheumatol , vol.31 , pp. 390-392
    • Petty, R.E.1    Southwood, T.R.2    Manners, P.3
  • 5
    • 0042193643 scopus 로고    scopus 로고
    • Are the number of joints involved or the presence of psoriasis still useful tools to identify homogeneous disease entities in juvenile idiopathic arthritis?
    • Martini A. Are the number of joints involved or the presence of psoriasis still useful tools to identify homogeneous disease entities in juvenile idiopathic arthritis? J Rheumatol 2003;30:1900-3
    • (2003) J Rheumatol , vol.30 , pp. 1900-1903
    • Martini, A.1
  • 6
    • 0031993121 scopus 로고    scopus 로고
    • Is systemic juvenile rheumatoid arthritis an interleukin 6 mediated disease?
    • De Benedetti F, Martini A. Is systemic juvenile rheumatoid arthritis an interleukin 6 mediated disease? J Rheumatol 1998;25:203-7
    • (1998) J Rheumatol , vol.25 , pp. 203-207
    • De Benedetti, F.1    Martini, A.2
  • 7
    • 14944373440 scopus 로고    scopus 로고
    • Targeting the interleukin-6 receptor: A new treatment for systemic juvenile idiopathic arthritis?
    • De Benedetti F, Martini A. Targeting the interleukin-6 receptor: A new treatment for systemic juvenile idiopathic arthritis? Arthritis Rheum 2005;52:687-93
    • (2005) Arthritis Rheum , vol.52 , pp. 687-693
    • De Benedetti, F.1    Martini, A.2
  • 8
    • 40749152243 scopus 로고    scopus 로고
    • Efficacy and safety of tocilizumab in patients with systemic-onset juvenile idiopathic arthritis: A randomised, double-blind, placebo-controlled, withdrawal Phase III trial
    • Phase III trial with tocilizuman in juvenile idiopathic arthritis
    • Yokota S, Imagawa T, Mori M, et al. Efficacy and safety of tocilizumab in patients with systemic-onset juvenile idiopathic arthritis: A randomised, double-blind, placebo-controlled, withdrawal Phase III trial. Lancet 2008;371:998-1006 Phase III trial with tocilizuman in juvenile idiopathic arthritis.
    • (2008) Lancet , vol.371 , pp. 998-1006
    • Yokota, S.1    Imagawa, T.2    Mori, M.3
  • 9
    • 79959357631 scopus 로고    scopus 로고
    • Efficacy and safety of tocilizumab in patients with systemic juvenile idiopathic arthritis (sJIA): 12-week data from the Phase III TENDER Trial
    • De Benedetti F, Brunner HI, Ruperto N, et al. Efficacy and safety of tocilizumab in patients with systemic juvenile idiopathic arthritis (sJIA): 12-week data from the Phase III TENDER Trial. Ann Rheum Dis 2010;69
    • (2010) Ann Rheum Dis , pp. 69
    • De Benedetti, F.1    Brunner, H.I.2    Ruperto, N.3
  • 10
    • 18644385243 scopus 로고    scopus 로고
    • Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade
    • Role of IL-1 in systemic juvenile idiopathic arthritis
    • Pascual V, Allantaz F, Arce E, et al. Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade. J Exp Med 2005;201:1479-86 Role of IL-1 in systemic juvenile idiopathic arthritis.
    • (2005) J Exp Med , vol.201 , pp. 1479-1486
    • Pascual, V.1    Allantaz, F.2    Arce, E.3
  • 11
    • 45349095718 scopus 로고    scopus 로고
    • A diagnostic score for molecular analysis of hereditary autoinflammatory syndromes with periodic fever in children
    • Gattorno M, Sormani MP, D'Osualdo A, et al. A diagnostic score for molecular analysis of hereditary autoinflammatory syndromes with periodic fever in children. Arthritis Rheum 2008;58:1823-32
    • (2008) Arthritis Rheum , vol.58 , pp. 1823-1832
    • Gattorno, M.1    Sormani, M.P.2    D'Osualdo, A.3
  • 12
    • 33746876396 scopus 로고    scopus 로고
    • Neonatal-onset multisystem inflammatory disease responsive to interleukin-1beta inhibition
    • Goldbach-Mansky R, Dailey NJ, Canna SW, et al. Neonatal-onset multisystem inflammatory disease responsive to interleukin-1beta inhibition. N Engl J Med 2006;355:581-92
    • (2006) N Engl J Med , vol.355 , pp. 581-592
    • Goldbach-Mansky, R.1    Dailey, N.J.2    Canna, S.W.3
  • 13
    • 34848875155 scopus 로고    scopus 로고
    • Pattern of interleukin-1beta secretion in response to lipopolysaccharide and ATP before and after interleukin-1 blockade in patients with CIAS1 mutations
    • Role of IL-1 in systemic juvenile idiopathic arthritis
    • Gattorno M, Tassi S, Carta S, et al. Pattern of interleukin-1beta secretion in response to lipopolysaccharide and ATP before and after interleukin-1 blockade in patients with CIAS1 mutations. Arthritis Rheum 2007;56:3138-48 Role of IL-1 in systemic juvenile idiopathic arthritis.
    • (2007) Arthritis Rheum , vol.56 , pp. 3138-3148
    • Gattorno, M.1    Tassi, S.2    Carta, S.3
  • 14
    • 79953323633 scopus 로고    scopus 로고
    • A multicentre, randomised, double-blind, placebo-controlled trial with the interleukin-1 receptor antagonist anakinra in patients with systemic-onset juvenile idiopathic arthritis (ANAJIS trial)
    • Quartier P, Allantaz F, Cimaz R, et al. A multicentre, randomised, double-blind, placebo-controlled trial with the interleukin-1 receptor antagonist anakinra in patients with systemic-onset juvenile idiopathic arthritis (ANAJIS trial). Ann Rheum Dis 2011;70:747-54
    • (2011) Ann Rheum Dis , vol.70 , pp. 747-754
    • Quartier, P.1    Allantaz, F.2    Cimaz, R.3
  • 15
    • 79551654446 scopus 로고    scopus 로고
    • Anakinra as first-line disease-modifying therapy in systemic juvenile idiopathic arthritis: Report of forty-six patients from an international multicenter series
    • Nigrovic PA, Mannion M, Prince FH, et al. Anakinra as first-line disease-modifying therapy in systemic juvenile idiopathic arthritis: Report of forty-six patients from an international multicenter series. Arthritis Rheum 2011;63:545-55
    • (2011) Arthritis Rheum , vol.63 , pp. 545-555
    • Nigrovic, P.A.1    Mannion, M.2    Prince, F.H.3
  • 16
    • 79959506175 scopus 로고    scopus 로고
    • Analysis of disease activity functional disability and articular damage in patients with juvenile idiopathic arthritis: A prospective outcome study
    • published online doi:3987 [pii]
    • Susic GZ, Stojanovic RM, Pejnovic NN, et al. Analysis of disease activity, functional disability and articular damage in patients with juvenile idiopathic arthritis: A prospective outcome study. Clin Exp Rheumatol 2011; published online, doi:3987 [pii]
    • (2011) Clin Exp Rheumatol
    • Susic, G.Z.1    Stojanovic, R.M.2    Pejnovic, N.N.3
  • 17
    • 70149106369 scopus 로고    scopus 로고
    • Inactive disease in polyarticular juvenile idiopathic arthritis: Current patterns and associations
    • Ringold S, Seidel KD, Koepsell TD, Wallace CA. Inactive disease in polyarticular juvenile idiopathic arthritis: Current patterns and associations. Rheumatology (Oxford) 2009;48:972-7
    • (2009) Rheumatology (Oxford) , vol.48 , pp. 972-977
    • Ringold, S.1    Seidel, K.D.2    Koepsell, T.D.3    Wallace, C.A.4
  • 18
    • 14944372145 scopus 로고    scopus 로고
    • Patients with antinuclear antibody-positive juvenile idiopathic arthritis constitute a homogeneous subgroup irrespective of the course of joint disease
    • Ravelli A, Felici E, Magni-Manzoni S, et al. Patients with antinuclear antibody-positive juvenile idiopathic arthritis constitute a homogeneous subgroup irrespective of the course of joint disease. Arthritis Rheum 2005;52:826-32
    • (2005) Arthritis Rheum , vol.52 , pp. 826-832
    • Ravelli, A.1    Felici, E.2    Magni-Manzoni, S.3
  • 19
    • 78650793943 scopus 로고    scopus 로고
    • Antinuclear antibody-positive patients should be grouped as a separate category in the classification of juvenile idiopathic arthritis
    • Ravelli A, Varnier GC, Oliveira S, et al. Antinuclear antibody-positive patients should be grouped as a separate category in the classification of juvenile idiopathic arthritis. Arthritis Rheum 2011;63:267-75
    • (2011) Arthritis Rheum , vol.63 , pp. 267-275
    • Ravelli, A.1    Varnier, G.C.2    Oliveira, S.3
  • 20
    • 47949107950 scopus 로고    scopus 로고
    • A longitudinal analysis of physical functional disability over the course of juvenile idiopathic arthritis
    • Magni-Manzoni S, Pistorio A, Labo E, et al. A longitudinal analysis of physical functional disability over the course of juvenile idiopathic arthritis. Ann Rheum Dis 2008;67:1159-64
    • (2008) Ann Rheum Dis , vol.67 , pp. 1159-1164
    • Magni-Manzoni, S.1    Pistorio, A.2    Labo, E.3
  • 21
    • 0034861802 scopus 로고    scopus 로고
    • Factors affecting the efficacy of intraarticular corticosteroid injection of knees in juvenile idiopathic arthritis
    • Ravelli A, Manzoni SM, Viola S, et al. Factors affecting the efficacy of intraarticular corticosteroid injection of knees in juvenile idiopathic arthritis. J Rheumatol 2001;28:2100-2
    • (2001) J Rheumatol , vol.28 , pp. 2100-2102
    • Ravelli, A.1    Manzoni, S.M.2    Viola, S.3
  • 22
    • 56049126403 scopus 로고    scopus 로고
    • Assessing current outcomes of juvenile idiopathic arthritis: A cross-sectional study in a tertiary center sample
    • Solari N, Viola S, Pistorio A, et al. Assessing current outcomes of juvenile idiopathic arthritis: A cross-sectional study in a tertiary center sample. Arthritis Rheum 2008;59:1571-9
    • (2008) Arthritis Rheum , vol.59 , pp. 1571-1579
    • Solari, N.1    Viola, S.2    Pistorio, A.3
  • 23
    • 67650045888 scopus 로고    scopus 로고
    • Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets
    • Griffin TA, Barnes MG, Ilowite NT, et al. Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets. Arthritis Rheum 2009;60:2113-23
    • (2009) Arthritis Rheum , vol.60 , pp. 2113-2123
    • Griffin, T.A.1    Barnes, M.G.2    Ilowite, N.T.3
  • 24
    • 77956377340 scopus 로고    scopus 로고
    • Biologic similarities based on age at onset in oligoarticular and polyarticular subtypes of juvenile idiopathic arthritis
    • Barnes MG, Grom AA, Thompson SD, et al. Biologic similarities based on age at onset in oligoarticular and polyarticular subtypes of juvenile idiopathic arthritis. Arthritis Rheum 2010;62:3249-58
    • (2010) Arthritis Rheum , vol.62 , pp. 3249-3258
    • Barnes, M.G.1    Grom, A.A.2    Thompson, S.D.3
  • 25
    • 39549121704 scopus 로고    scopus 로고
    • The magnitude of early response to methotrexate therapy predicts long-term outcome of patients with juvenile idiopathic arthritis
    • Bartoli M, Taro M, Magni-Manzoni S, et al. The magnitude of early response to methotrexate therapy predicts long-term outcome of patients with juvenile idiopathic arthritis. Ann Rheum Dis 2008;67:370-4
    • (2008) Ann Rheum Dis , vol.67 , pp. 370-374
    • Bartoli, M.1    Taro, M.2    Magni-Manzoni, S.3
  • 26
    • 38649099725 scopus 로고    scopus 로고
    • Comparison of Vancouver and International League of Associations for rheumatology classification criteria for juvenile psoriatic arthritis
    • Stoll ML, Lio P, Sundel RP, Nigrovic PA. Comparison of Vancouver and International League of Associations for rheumatology classification criteria for juvenile psoriatic arthritis. Arthritis Rheum 2008;59:51-8
    • (2008) Arthritis Rheum , vol.59 , pp. 51-58
    • Stoll, M.L.1    Lio, P.2    Sundel, R.P.3    Nigrovic, P.A.4
  • 27
    • 33750932012 scopus 로고    scopus 로고
    • Patients with juvenile psoriatic arthritis comprise two distinct populations
    • Stoll ML, Zurakowski D, Nigrovic LE, et al. Patients with juvenile psoriatic arthritis comprise two distinct populations. Arthritis Rheum 2006;54:3564-72
    • (2006) Arthritis Rheum , vol.54 , pp. 3564-3572
    • Stoll, M.L.1    Zurakowski, D.2    Nigrovic, L.E.3
  • 28
    • 0032888041 scopus 로고    scopus 로고
    • A look at the future of pediatric therapeutics: An investigator's perspective of the new pediatric rule
    • Connor JD. A look at the future of pediatric therapeutics: An investigator's perspective of the new pediatric rule. Pediatrics 1999;104:610-13
    • (1999) Pediatrics , vol.104 , pp. 610-613
    • Connor, J.D.1
  • 29
    • 85007680228 scopus 로고    scopus 로고
    • Use of unlabelled and off licence drugs in children. A European paediatric rule is needed to protect children
    • for the Paediatric Rheumatology International Trials Organization (PRINTO)
    • Ruperto N, Martini A, for the Paediatric Rheumatology International Trials Organization (PRINTO). Use of unlabelled and off licence drugs in children. A European paediatric rule is needed to protect children. BMJ 2000;320:1210-11
    • (2000) BMJ , vol.320 , pp. 1210-1211
    • Ruperto, N.1    Martini, A.2
  • 30
    • 79956299521 scopus 로고    scopus 로고
    • Networking in pediatrics: The example of the Pediatric Rheumatology International Trials Organisation (PRINTO)
    • for the Paediatric Rheumatology International Trials Organisation (PRINTO). epub ahed of print The role of networking in pediatric rheumatology
    • Ruperto N, Martini A, for the Paediatric Rheumatology International Trials Organisation (PRINTO). Networking in pediatrics: The example of the Pediatric Rheumatology International Trials Organisation (PRINTO). Arch Dis Child 2011;epub ahed of print The role of networking in pediatric rheumatology.
    • (2011) Arch Dis Child
    • Ruperto, N.1    Martini, A.2
  • 31
    • 4344638042 scopus 로고    scopus 로고
    • International research networks in pediatric rheumatology: The PRINTO perspective
    • Ruperto N, Martini A. International research networks in pediatric rheumatology: The PRINTO perspective. Curr Opin Rheumatol 2004;16:566-70
    • (2004) Curr Opin Rheumatol , vol.16 , pp. 566-570
    • Ruperto, N.1    Martini, A.2
  • 32
    • 78249278823 scopus 로고    scopus 로고
    • Is it time to move to active comparator trials in juvenile idiopathic arthritis? A review of current study designs
    • Current study designs in juvenile idiopathic arthritis
    • Ruperto N, Giannini EH, Pistorio A, et al. Is it time to move to active comparator trials in juvenile idiopathic arthritis? A review of current study designs. Arthritis Rheum 2010;62:3131-9 Current study designs in juvenile idiopathic arthritis.
    • (2010) Arthritis Rheum , vol.62 , pp. 3131-3139
    • Ruperto, N.1    Giannini, E.H.2    Pistorio, A.3
  • 33
    • 0029982473 scopus 로고    scopus 로고
    • Intravenous immunoglobulin in the treatment of polyarticular juvenile rheumatoid arthritis: A Phase I/II study
    • Giannini EH, Lovell DJ, Silverman ED, et al. Intravenous immunoglobulin in the treatment of polyarticular juvenile rheumatoid arthritis: A Phase I/II study. J Rheumatol 1996;23:919-24
    • (1996) J Rheumatol , vol.23 , pp. 919-924
    • Giannini, E.H.1    Lovell, D.J.2    Silverman, E.D.3
  • 34
    • 0030960980 scopus 로고    scopus 로고
    • Preliminary definition of improvement in juvenile arthritis
    • Criteria to evaluate response to therapy in juvenile idiopathic arthritis
    • Giannini EH, Ruperto N, Ravelli A, et al. Preliminary definition of improvement in juvenile arthritis. Arthritis Rheum 1997;40:1202-9 Criteria to evaluate response to therapy in juvenile idiopathic arthritis.
    • (1997) Arthritis Rheum , vol.40 , pp. 1202-1209
    • Giannini, E.H.1    Ruperto, N.2    Ravelli, A.3
  • 35
    • 77954438269 scopus 로고    scopus 로고
    • Synovial and inflammatory diseases in childhood: Role of new imaging modalities in the assessment of patients with juvenile idiopathic arthritis
    • Damasio MB, Malattia C, Martini A, Toma P. Synovial and inflammatory diseases in childhood: Role of new imaging modalities in the assessment of patients with juvenile idiopathic arthritis. Pediatr Radiol 2010;40:985-98
    • (2010) Pediatr Radiol , vol.40 , pp. 985-998
    • Damasio, M.B.1    Malattia, C.2    Martini, A.3    Toma, P.4
  • 36
    • 35148814384 scopus 로고    scopus 로고
    • Radiologic investigation of rheumatic diseases
    • Babyn P, Doria AS. Radiologic investigation of rheumatic diseases. Rheum Dis Clin North Am 2007;33:403-40
    • (2007) Rheum Dis Clin North Am , vol.33 , pp. 403-440
    • Babyn, P.1    Doria, A.S.2
  • 37
    • 34848913504 scopus 로고    scopus 로고
    • Adapted versions of the Sharp/van der Heijde score are reliable and valid for assessment of radiographic progression in juvenile idiopathic arthritis
    • Ravelli A, Ioseliani M, Norambuena X, et al. Adapted versions of the Sharp/van der Heijde score are reliable and valid for assessment of radiographic progression in juvenile idiopathic arthritis. Arthritis Rheum 2007;56:3087-95
    • (2007) Arthritis Rheum , vol.56 , pp. 3087-3095
    • Ravelli, A.1    Ioseliani, M.2    Norambuena, X.3
  • 38
    • 57149094052 scopus 로고    scopus 로고
    • Magnetic resonance imaging, ultrasonography, and conventional radiography in the assessment of bone erosions in juvenile idiopathic arthritis
    • Malattia C, Damasio MB, Magnaguagno F, et al. Magnetic resonance imaging, ultrasonography, and conventional radiography in the assessment of bone erosions in juvenile idiopathic arthritis. Arthritis Rheum 2008;59:1764-72
    • (2008) Arthritis Rheum , vol.59 , pp. 1764-1772
    • Malattia, C.1    Damasio, M.B.2    Magnaguagno, F.3
  • 39
    • 79951510538 scopus 로고    scopus 로고
    • Development and preliminary validation of a paediatric-targeted MRI scoring system for the assessment of disease activity and damage in juvenile idiopathic arthritis
    • published online doi: Ard. 2009.126862 [pii];10.1136/ ard.2009.126862 [doi]
    • Malattia C, Damasio MB, Pistorio A, et al. Development and preliminary validation of a paediatric-targeted MRI scoring system for the assessment of disease activity and damage in juvenile idiopathic arthritis. Ann Rheum Dis 2010; published online, doi: Ard.2009.126862 [pii];10.1136/ ard.2009.126862 [doi]
    • (2010) Ann Rheum Dis
    • Malattia, C.1    Damasio, M.B.2    Pistorio, A.3
  • 40
    • 0026609159 scopus 로고
    • Methotrexate in resistant juvenile rheumatoid arthritis. Results of the USAUSSR. double-blind, placebo-controlled trial
    • Phase III trial with methotrexate in juvenile idiopathic arthritis
    • Giannini EH, Brewer EJ, Kuzmina N, et al. Methotrexate in resistant juvenile rheumatoid arthritis. Results of the USAUSSR. double-blind, placebo-controlled trial. N Engl J Med 1992;326:1043-9 Phase III trial with methotrexate in juvenile idiopathic arthritis.
    • (1992) N Engl J Med , vol.326 , pp. 1043-1049
    • Giannini, E.H.1    Brewer, E.J.2    Kuzmina, N.3
  • 41
    • 3142746016 scopus 로고    scopus 로고
    • A randomized trial of parenteral methotrexate comparing an intermediate dose with a higher dose in children with juvenile idiopathic arthritis who failed to respond to standard doses of methotrexate
    • Phase III trial with higher methotrexate doses in juvenile idiopathic arthritis
    • Ruperto N, Murray KJ, Gerloni V, et al. A randomized trial of parenteral methotrexate comparing an intermediate dose with a higher dose in children with juvenile idiopathic arthritis who failed to respond to standard doses of methotrexate. Arthritis Rheum 2004;50:2191-201 Phase III trial with higher methotrexate doses in juvenile idiopathic arthritis.
    • (2004) Arthritis Rheum , vol.50 , pp. 2191-2201
    • Ruperto, N.1    Murray, K.J.2    Gerloni, V.3
  • 42
    • 20244384845 scopus 로고    scopus 로고
    • Leflunomide or methotrexate for juvenile rheumatoid arthritis
    • Phase III trial with leflunomide in juvenile idiopathic arthritis
    • Silverman E, Mouy R, Spiegel L, et al. Leflunomide or methotrexate for juvenile rheumatoid arthritis. N Engl J Med 2005;352:1655-66 Phase III trial with leflunomide in juvenile idiopathic arthritis.
    • (2005) N Engl J Med , vol.352 , pp. 1655-1666
    • Silverman, E.1    Mouy, R.2    Spiegel, L.3
  • 43
    • 0031969434 scopus 로고    scopus 로고
    • Sulfasalazine in the treatment of juvenile chronic arthritis: A randomized, double-blind, placebo-controlled, multicenter study
    • Dutch Juvenile Chronic Arthritis Study Group, Phase III trial with sulfasalazine in juvenile idiopathic arthritis
    • Van Rossum MA, Fiselier TJ, Franssen MJ, et al. Sulfasalazine in the treatment of juvenile chronic arthritis: A randomized, double-blind, placebo-controlled, multicenter study. Dutch Juvenile Chronic Arthritis Study Group. Arthritis Rheum 1998;41:808-16 Phase III trial with sulfasalazine in juvenile idiopathic arthritis.
    • (1998) Arthritis Rheum , vol.41 , pp. 808-816
    • Van Rossum, M.A.1    Fiselier, T.J.2    Franssen, M.J.3
  • 44
    • 79957483535 scopus 로고    scopus 로고
    • 2011 American College of Rheumatology recommendations for the treatment of juvenile idiopathic arthritis: Initiation and safety monitoring of therapeutic agents for the treatment of arthritis and systemic features
    • American College of Rheumatology recommendation for the treatment of JIA
    • Beukelman T, Patkar NM, Saag KG, et al. 2011 American College of Rheumatology recommendations for the treatment of juvenile idiopathic arthritis: Initiation and safety monitoring of therapeutic agents for the treatment of arthritis and systemic features. Arthritis Care Res (Hoboken) 2011;63:465-82 American College of Rheumatology recommendation for the treatment of JIA.
    • (2011) Arthritis Care Res (Hoboken) , vol.63 , pp. 465-482
    • Beukelman, T.1    Patkar, N.M.2    Saag, K.G.3
  • 45
    • 0034673697 scopus 로고    scopus 로고
    • Etanercept in children with polyarticular juvenile rheumatoid arthritis
    • Phase III trial with etanercept in juvenile idiopathic arthritis
    • Lovell DJ, Giannini EH, Reiff A, et al. Etanercept in children with polyarticular juvenile rheumatoid arthritis. N Engl J Med 2000;342:763-9 Phase III trial with etanercept in juvenile idiopathic arthritis.
    • (2000) N Engl J Med , vol.342 , pp. 763-769
    • Lovell, D.J.1    Giannini, E.H.2    Reiff, A.3
  • 46
    • 9644255827 scopus 로고    scopus 로고
    • The German etanercept registry for treatment of juvenile idiopathic arthritis
    • Phase IV study with etanercept in juvenile idiopathic arthritis
    • Horneff G, Schmeling H, Biedermann T, et al. The German etanercept registry for treatment of juvenile idiopathic arthritis. Ann Rheum Dis 2004;63:1638-44 Phase IV study with etanercept in juvenile idiopathic arthritis.
    • (2004) Ann Rheum Dis , vol.63 , pp. 1638-1644
    • Horneff, G.1    Schmeling, H.2    Biedermann, T.3
  • 47
    • 66149142293 scopus 로고    scopus 로고
    • Long-term follow-up on effectiveness and safety of etanercept in juvenile idiopathic arthritis: The Dutch national register
    • Prince FH, Twilt M, Ten CR, et al. Long-term follow-up on effectiveness and safety of etanercept in juvenile idiopathic arthritis: The Dutch national register. Ann Rheum Dis 2009;68:635-41
    • (2009) Ann Rheum Dis , vol.68 , pp. 635-641
    • Prince, F.H.1    Twilt, M.2    Ten, C.R.3
  • 48
    • 78249250295 scopus 로고    scopus 로고
    • Effects of long-term etanercept treatment on growth in children with selected categories of juvenile idiopathic arthritis
    • Giannini EH, Ilowite NT, Lovell DJ, et al. Effects of long-term etanercept treatment on growth in children with selected categories of juvenile idiopathic arthritis. Arthritis Rheum 2010;62:3259-64
    • (2010) Arthritis Rheum , vol.62 , pp. 3259-3264
    • Giannini, E.H.1    Ilowite, N.T.2    Lovell, D.J.3
  • 49
    • 34848884299 scopus 로고    scopus 로고
    • A randomized, placebo-controlled trial of infliximab plus methotrexate for the treatment of polyarticular-course juvenile rheumatoid arthritis
    • Phase III trial with infliximab in juvenile idiopathic arthritis
    • Ruperto N, Lovell DJ, Cuttica R, et al. A randomized, placebo-controlled trial of infliximab plus methotrexate for the treatment of polyarticular-course juvenile rheumatoid arthritis. Arthritis Rheum 2007;56:3096-106 Phase III trial with infliximab in juvenile idiopathic arthritis.
    • (2007) Arthritis Rheum , vol.56 , pp. 3096-3106
    • Ruperto, N.1    Lovell, D.J.2    Cuttica, R.3
  • 50
    • 77950301852 scopus 로고    scopus 로고
    • Long-term efficacy and safety of infliximab plus methotrexate for the treatment of polyarticular-course juvenile rheumatoid arthritis: Findings from an open-label treatment extension
    • Ruperto N, Lovell DJ, Cuttica R, et al. Long-term efficacy and safety of infliximab plus methotrexate for the treatment of polyarticular-course juvenile rheumatoid arthritis: Findings from an open-label treatment extension. Ann Rheum Dis 2010;69:718-22
    • (2010) Ann Rheum Dis , vol.69 , pp. 718-722
    • Ruperto, N.1    Lovell, D.J.2    Cuttica, R.3
  • 51
    • 49949115223 scopus 로고    scopus 로고
    • Adalimumab with or without methotrexate in juvenile rheumatoid arthritis
    • Phase III trial with adalimumab in juvenile idiopathic arthritis
    • Lovell DJ, Ruperto N, Goodman S, et al. Adalimumab with or without methotrexate in juvenile rheumatoid arthritis. N Engl J Med 2008;359:810-20 Phase III trial with adalimumab in juvenile idiopathic arthritis.
    • (2008) N Engl J Med , vol.359 , pp. 810-820
    • Lovell, D.J.1    Ruperto, N.2    Goodman, S.3
  • 52
    • 65249098979 scopus 로고    scopus 로고
    • Safety and efficacy of combination of etanercept and methotrexate compared to treatment with etanercept only in patients with juvenile idiopathic arthritis (JIA): Preliminary data from the German JIA Registry
    • Horneff G, De BF, Foeldvari I, et al. Safety and efficacy of combination of etanercept and methotrexate compared to treatment with etanercept only in patients with juvenile idiopathic arthritis (JIA): Preliminary data from the German JIA Registry. Ann Rheum Dis 2009;68:519-25
    • (2009) Ann Rheum Dis , vol.68 , pp. 519-525
    • Horneff, G.1    De, B.F.2    Foeldvari, I.3
  • 53
    • 52649108201 scopus 로고    scopus 로고
    • Preliminary evidence that etanercept may reduce radiographic progression in juvenile idiopathic arthritis
    • Nielsen S, Ruperto N, Gerloni V, et al. Preliminary evidence that etanercept may reduce radiographic progression in juvenile idiopathic arthritis. Clin Exp Rheumatol 2008;26:688-92
    • (2008) Clin Exp Rheumatol , vol.26 , pp. 688-692
    • Nielsen, S.1    Ruperto, N.2    Gerloni, V.3
  • 54
    • 77957584399 scopus 로고    scopus 로고
    • The safety profile of biologic therapies for juvenile idiopathic arthritis
    • published online doi: Nrrheum.2010.142 [pii];10.1038/ nrrheum.2010.142 [doi]
    • Hashkes PJ, Uziel Y, Laxer RM. The safety profile of biologic therapies for juvenile idiopathic arthritis. Nat Rev Rheumatol 2010; published online, doi: Nrrheum.2010.142 [pii];10.1038/ nrrheum.2010.142 [doi]
    • (2010) Nat Rev Rheumatol
    • Hashkes, P.J.1    Uziel, Y.2    Laxer, R.M.3
  • 55
    • 77955371398 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha blockers and malignancy in children: Forty-eight cases reported to the Food and Drug Administration
    • Diak P, Siegel J, La GL, et al. Tumor necrosis factor alpha blockers and malignancy in children: Forty-eight cases reported to the Food and Drug Administration. Arthritis Rheum 2010;62:2517-24
    • (2010) Arthritis Rheum , vol.62 , pp. 2517-2524
    • Diak, P.1    Siegel J La, G.L.2
  • 56
    • 78649648584 scopus 로고    scopus 로고
    • Juvenile idiopathic arthritis and risk of cancer: A nationwide cohort study
    • published online doi:10.1002/art. 27741 [doi] Risk of cancer in juvenile idiopathic arthritis
    • Simard J, Neovius M, Hagelberg S, Askling J. Juvenile idiopathic arthritis and risk of cancer: A nationwide cohort study. Arthritis Rheum 2010; published online, doi:10.1002/art. 27741 [doi] Risk of cancer in juvenile idiopathic arthritis.
    • (2010) Arthritis Rheum
    • Simard, J.1    Neovius, M.2    Hagelberg, S.3    Askling, J.4
  • 57
    • 78650990577 scopus 로고    scopus 로고
    • Pediatric rheumatology: JIA, treatment and possible risk of malignancies
    • Ruperto N, Martini A. Pediatric rheumatology: JIA, treatment and possible risk of malignancies. Nat Rev Rheumatol 2011;7:6-7
    • (2011) Nat Rev Rheumatol , vol.7 , pp. 6-7
    • Ruperto, N.1    Martini, A.2
  • 58
    • 79951691845 scopus 로고    scopus 로고
    • Report on malignancies in the German juvenile idiopathic arthritis registry
    • Risk of cancer in juvenile idiopathic arthritis
    • Horneff G, Foeldvari I, Minden K, et al. Report on malignancies in the German juvenile idiopathic arthritis registry. Rheumatology (Oxford) 2011;50:230-6 Risk of cancer in juvenile idiopathic arthritis.
    • (2011) Rheumatology (Oxford) , vol.50 , pp. 230-236
    • Horneff, G.1    Foeldvari, I.2    Minden, K.3
  • 59
    • 79953317032 scopus 로고    scopus 로고
    • Malignancies in juvenile idiopathic arthritis: A preliminary report
    • Risk of cancer in juvenile idiopathic arthritis
    • Bernatsky S, Rosenberg AM, Oen KG, et al. Malignancies in juvenile idiopathic arthritis: A preliminary report. J Rheumatol 2011;38:760-3 Risk of cancer in juvenile idiopathic arthritis.
    • (2011) J Rheumatol , vol.38 , pp. 760-763
    • Bernatsky, S.1    Rosenberg, A.M.2    Oen, K.G.3
  • 60
    • 48349093002 scopus 로고    scopus 로고
    • Abatacept in children with juvenile idiopathic arthritis: A randomised, double-blind, placebo-controlled withdrawal trial
    • Phase III trial with abatacept in juvenile idiopathic arthritis
    • Ruperto N, Lovell DJ, Quartier P, et al. Abatacept in children with juvenile idiopathic arthritis: A randomised, double-blind, placebo-controlled withdrawal trial. Lancet 2008;372:383-91 Phase III trial with abatacept in juvenile idiopathic arthritis.
    • (2008) Lancet , vol.372 , pp. 383-391
    • Ruperto, N.1    Lovell, D.J.2    Quartier, P.3
  • 61
    • 79952063531 scopus 로고    scopus 로고
    • Abatacept improves health-related quality of life, pain, sleep quality and daily participation in subjects with juvenile idiopathic arthritis
    • Ruperto N, Lovell DJ, Li T, et al. Abatacept improves health-related quality of life, pain, sleep quality and daily participation in subjects with juvenile idiopathic arthritis. Arthritis Care Res 2010;62:1542-51
    • (2010) Arthritis Care Res , vol.62 , pp. 1542-1551
    • Ruperto, N.1    Lovell, D.J.2    Li, T.3
  • 62
    • 77952898132 scopus 로고    scopus 로고
    • Long-term safety and efficacy of abatacept in children with juvenile idiopathic arthritis
    • published online doi:10.1002/ art.27431 [doi]
    • Ruperto N, Lovell DJ, Quartier P, et al. Long-term safety and efficacy of abatacept in children with juvenile idiopathic arthritis. Arthritis Rheum 2010; published online, doi:10.1002/ art.27431 [doi]
    • (2010) Arthritis Rheum
    • Ruperto, N.1    Lovell, D.J.2    Quartier, P.3
  • 63
    • 69249203713 scopus 로고    scopus 로고
    • Recent developments in anti-rheumatic drugs in pediatrics: Treatment of juvenile idiopathic arthritis
    • Hayward K, Wallace CA. Recent developments in anti-rheumatic drugs in pediatrics: Treatment of juvenile idiopathic arthritis. Arthritis Res 2009;11:216-27
    • (2009) Arthritis Res , vol.11 , pp. 216-227
    • Hayward, K.1    Wallace, C.A.2
  • 64
    • 77955307038 scopus 로고    scopus 로고
    • Current therapeutic approaches to autoimmune chronic uveitis in children
    • Simonini G, Cantarini L, Bresci C, et al. Current therapeutic approaches to autoimmune chronic uveitis in children. Autoimmun Rev 2010;9:674-83
    • (2010) Autoimmun Rev , vol.9 , pp. 674-683
    • Simonini, G.1    Cantarini, L.2    Bresci, C.3
  • 65
    • 49549118435 scopus 로고    scopus 로고
    • Development and validation of a preliminary definition of minimal disease activity in patients with juvenile idiopathic arthritis
    • Magni-Manzoni S, Ruperto N, Pistorio A, et al. Development and validation of a preliminary definition of minimal disease activity in patients with juvenile idiopathic arthritis. Arthritis Rheum 2008;59:1120-7
    • (2008) Arthritis Rheum , vol.59 , pp. 1120-1127
    • Magni-Manzoni, S.1    Ruperto, N.2    Pistorio, A.3
  • 66
    • 7544222361 scopus 로고    scopus 로고
    • Preliminary criteria for clinical remission for select categories of juvenile idiopathic arthritis
    • Wallace CA, Ruperto N, Giannini E, et al. Preliminary criteria for clinical remission for select categories of juvenile idiopathic arthritis. J Rheumatol 2004;31:2290-4
    • (2004) J Rheumatol , vol.31 , pp. 2290-2294
    • Wallace, C.A.1    Ruperto, N.2    Giannini, E.3
  • 67
    • 33750697627 scopus 로고    scopus 로고
    • Remission in juvenile idiopathic arthritis
    • Ravelli A, Martini A. Remission in juvenile idiopathic arthritis. Clin Exp Rheumatol 2006;24:S105-10
    • (2006) Clin Exp Rheumatol , vol.24
    • Ravelli, A.1    Martini, A.2
  • 68
    • 67650478336 scopus 로고    scopus 로고
    • Accuracy of Wallace criteria for clinical remission in juvenile idiopathic arthritis: A cohort study of 761 consecutive cases
    • Lurati A, Salmaso A, Gerloni V, et al. Accuracy of Wallace criteria for clinical remission in juvenile idiopathic arthritis: A cohort study of 761 consecutive cases. J Rheumatol 2009;36:1532-5
    • (2009) J Rheumatol , vol.36 , pp. 1532-1535
    • Lurati, A.1    Salmaso, A.2    Gerloni, V.3
  • 69
    • 77950512831 scopus 로고    scopus 로고
    • Methotrexate withdrawal at 6 vs 12 months in juvenile idiopathic arthritis in remission: A randomized clinical trial
    • Phase III trial for methotrexate discontinuation in juvenile idiopathic arthritis in remission
    • Foell D, Wulffraat N, Wedderburn LR, et al. Methotrexate withdrawal at 6 vs 12 months in juvenile idiopathic arthritis in remission: A randomized clinical trial. JAMA 2010;303:1266-73 Phase III trial for methotrexate discontinuation in juvenile idiopathic arthritis in remission.
    • (2010) JAMA , vol.303 , pp. 1266-1273
    • Foell, D.1    Wulffraat, N.2    Wedderburn, L.R.3
  • 70
    • 77953256541 scopus 로고    scopus 로고
    • Targeting IL-17 and Th17 cells in rheumatoid arthritis
    • Sarkar S, Fox DA. Targeting IL-17 and Th17 cells in rheumatoid arthritis. Rheum Dis Clin North Am 2010;36:345-66
    • (2010) Rheum Dis Clin North Am , vol.36 , pp. 345-366
    • Sarkar, S.1    Fox, D.A.2
  • 71
    • 70349968220 scopus 로고    scopus 로고
    • IL-17 as a future therapeutic target for rheumatoid arthritis
    • Van den Berg WB, Miossec P. IL-17 as a future therapeutic target for rheumatoid arthritis. Nat Rev Rheumatol 2009;5:549-53
    • (2009) Nat Rev Rheumatol , vol.5 , pp. 549-553
    • Van Den Berg, W.B.1    Miossec, P.2
  • 72
    • 78649544524 scopus 로고    scopus 로고
    • The transient nature of the Th17 phenotype
    • Annunziato F, Romagnani S. The transient nature of the Th17 phenotype. Eur J Immunol 2010;40:3312-16
    • (2010) Eur J Immunol , vol.40 , pp. 3312-3316
    • Annunziato, F.1    Romagnani, S.2
  • 73
    • 40649083317 scopus 로고    scopus 로고
    • Interleukin 17 levels are increased in juvenile idiopathic arthritis synovial fluid and induce synovial fibroblasts to produce proinflammatory cytokines and matrix metalloproteinases
    • Agarwal S, Misra R, Aggarwal A. Interleukin 17 levels are increased in juvenile idiopathic arthritis synovial fluid and induce synovial fibroblasts to produce proinflammatory cytokines and matrix metalloproteinases. J Rheumatol 2008;35:515-19
    • (2008) J Rheumatol , vol.35 , pp. 515-519
    • Agarwal, S.1    Misra, R.2    Aggarwal, A.3
  • 74
    • 70349245581 scopus 로고    scopus 로고
    • Th17 transcription factor RORC2 is inversely correlated with FOXP3 expression in the joints of children with juvenile idiopathic arthritis
    • Olivito B, Simonini G, Ciullini S, et al. Th17 transcription factor RORC2 is inversely correlated with FOXP3 expression in the joints of children with juvenile idiopathic arthritis. J Rheumatol 2009;36:2017-24
    • (2009) J Rheumatol , vol.36 , pp. 2017-2024
    • Olivito, B.1    Simonini, G.2    Ciullini, S.3
  • 75
    • 40549138745 scopus 로고    scopus 로고
    • Interleukin-17-producing T cells are enriched in the joints of children with arthritis, but have a reciprocal relationship to regulatory T cell numbers
    • Nistala K, Moncrieffe H, Newton KR, et al. Interleukin-17-producing T cells are enriched in the joints of children with arthritis, but have a reciprocal relationship to regulatory T cell numbers. Arthritis Rheum 2008;58:875-87
    • (2008) Arthritis Rheum , vol.58 , pp. 875-887
    • Nistala, K.1    Moncrieffe, H.2    Newton, K.R.3
  • 76
    • 77957032994 scopus 로고    scopus 로고
    • Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment
    • Nistala K, Adams S, Cambrook H, et al. Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment. Proc Natl Acad Sci USA 2010;107:14751-6
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 14751-14756
    • Nistala, K.1    Adams, S.2    Cambrook, H.3
  • 77
    • 77950535421 scopus 로고    scopus 로고
    • LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A Phase I randomized, double-blind, placebo-controlled, proof-of-concept study
    • Genovese MC, Van den Bosch F, Roberson SA, et al. LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A Phase I randomized, double-blind, placebo-controlled, proof-of-concept study. Arthritis Rheum 2010;62:929-39
    • (2010) Arthritis Rheum , vol.62 , pp. 929-939
    • Genovese, M.C.1    Van Den Bosch, F.2    Roberson, S.A.3
  • 78
    • 70349926431 scopus 로고    scopus 로고
    • AIN457, an anti-IL17 antibody, shows goodsafety and induces clinical responses in patients with active rheumatoid arthritis (RA) despite methotrexate therapy in a randomized, double-blind proof-of-concept trial
    • Durez P, Chindalore V, Bittmer B. AIN457, an anti-IL17 antibody, shows goodsafety and induces clinical responses in patients with active rheumatoid arthritis (RA) despite methotrexate therapy in a randomized, double-blind proof-of-concept trial. Ann Rheum Dis 2009;68:125
    • (2009) Ann Rheum Dis , vol.68 , pp. 125
    • Durez, P.1    Chindalore, V.2    Bittmer, B.3
  • 79
    • 41449110468 scopus 로고    scopus 로고
    • Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome
    • Milner JD, Brenchley JM, Laurence A, et al. Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome. Nature 2008;452:773-6
    • (2008) Nature , vol.452 , pp. 773-776
    • Milner, J.D.1    Brenchley, J.M.2    Laurence, A.3
  • 80
    • 77149124612 scopus 로고    scopus 로고
    • Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I
    • Puel A, Doffinger R, Natividad A, et al. Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I. J Exp Med 2010;207:291-7
    • (2010) J Exp Med , vol.207 , pp. 291-297
    • Puel, A.1    Doffinger, R.2    Natividad, A.3
  • 81
    • 74049134371 scopus 로고    scopus 로고
    • Mixed results with modulation of TH-17 cells in human autoimmune diseases
    • Steinman L. Mixed results with modulation of TH-17 cells in human autoimmune diseases. Nat Immunol 2010;11:41-4
    • (2010) Nat Immunol , vol.11 , pp. 41-44
    • Steinman, L.1
  • 82
    • 60249084148 scopus 로고    scopus 로고
    • Ustekinumab, a human interleukin 12/23 monoclonal antibody, for psoriatic arthritis: Randomised, double-blind, placebo-controlled, crossover trial
    • Gottlieb A, Menter A, Mendelsohn A, et al. Ustekinumab, a human interleukin 12/23 monoclonal antibody, for psoriatic arthritis: Randomised, double-blind, placebo-controlled, crossover trial. Lancet 2009;373:633-40
    • (2009) Lancet , vol.373 , pp. 633-640
    • Gottlieb, A.1    Menter, A.2    Mendelsohn, A.3
  • 83
    • 80052005268 scopus 로고    scopus 로고
    • A Phase IIa, randomized, placebo-controlled clinical study of Apilimod Mesylate, an oral IL-12/IL-23 inhibitor, in patients with active rheumatoid arthritis
    • Krausz S, Boumans MJH, Gerlag DM. A Phase IIa, randomized, placebo-controlled clinical study of Apilimod Mesylate, an oral IL-12/IL-23 inhibitor, in patients with active rheumatoid arthritis. Arthritis Rheum 2010;10(S):S458
    • (2010) Arthritis Rheum , vol.10 , Issue.S
    • Krausz, S.1    Boumans, M.J.H.2    Gerlag, D.M.3
  • 84
    • 77953693548 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled trial of the oral interleukin-12/23 inhibitor apilimod mesylate for treatment of active Crohn's disease
    • Sands BE, Jacobson EW, Sylwestrowicz T, et al. Randomized, double-blind, placebo-controlled trial of the oral interleukin-12/23 inhibitor apilimod mesylate for treatment of active Crohn's disease. Inflamm Bowel Dis 2010;16:1209-18
    • (2010) Inflamm Bowel Dis , vol.16 , pp. 1209-1218
    • Sands, B.E.1    Jacobson, E.W.2    Sylwestrowicz, T.3
  • 85
    • 77956158598 scopus 로고    scopus 로고
    • Targeting the B cell in rheumatoid arthritis
    • Cohen SB. Targeting the B cell in rheumatoid arthritis. Best Pract Res Clin Rheumatol 2010;24:553-63
    • (2010) Best Pract Res Clin Rheumatol , vol.24 , pp. 553-563
    • Cohen, S.B.1
  • 86
    • 79951553465 scopus 로고    scopus 로고
    • EULAR recommendations for vaccination in adult patients with autoimmune inflammatory rheumatic diseases
    • van AS, Agmon-Levin N, Elkayam O, et al. EULAR recommendations for vaccination in adult patients with autoimmune inflammatory rheumatic diseases. Ann Rheum Dis 2011;70:414-22
    • (2011) Ann Rheum Dis , vol.70 , pp. 414-422
    • Van, A.S.1    Agmon-Levin, N.2    Elkayam, O.3
  • 87
    • 74849096560 scopus 로고    scopus 로고
    • Immunization responses in rheumatoid arthritis patients treated with rituximab: Results from a controlled clinical trial
    • Bingham CO III, Looney RJ, Deodhar A, et al. Immunization responses in rheumatoid arthritis patients treated with rituximab: Results from a controlled clinical trial. Arthritis Rheum 2010;62:64-74
    • (2010) Arthritis Rheum , vol.62 , pp. 64-74
    • Bingham III, C.O.1    Looney, R.J.2    Deodhar, A.3
  • 88
    • 74849103999 scopus 로고    scopus 로고
    • Humoral responses after influenza vaccination are severely reduced in patients with rheumatoid arthritis treated with rituximab
    • van Assen S, Holvast A, Benne CA, et al. Humoral responses after influenza vaccination are severely reduced in patients with rheumatoid arthritis treated with rituximab. Arthritis Rheum 2010;62:75-81
    • (2010) Arthritis Rheum , vol.62 , pp. 75-81
    • Van Assen, S.1    Holvast, A.2    Benne, C.A.3
  • 89
    • 38149138097 scopus 로고    scopus 로고
    • The effects of rituximab on immunocompetency in patients with autoimmune disease
    • Looney RJ, Srinivasan R, Calabrese LH. The effects of rituximab on immunocompetency in patients with autoimmune disease. Arthritis Rheum 2008;58:5-14
    • (2008) Arthritis Rheum , vol.58 , pp. 5-14
    • Looney, R.J.1    Srinivasan, R.2    Calabrese, L.H.3
  • 90
    • 49449116285 scopus 로고    scopus 로고
    • Rituximab treatment in children: Comment on the review by Looney et al
    • Bader-Meunier B. Rituximab treatment in children: Comment on the review by Looney, et al. Arthritis Rheum 2008;58:2583-4
    • (2008) Arthritis Rheum , vol.58 , pp. 2583-2584
    • Bader-Meunier, B.1
  • 91
    • 0035802696 scopus 로고    scopus 로고
    • Treatment of childhood autoimmune haemolytic anaemia with rituximab
    • Quartier P, Brethon B, Philippet P, et al. Treatment of childhood autoimmune haemolytic anaemia with rituximab. Lancet 2001;358:1511-13
    • (2001) Lancet , vol.358 , pp. 1511-1513
    • Quartier, P.1    Brethon, B.2    Philippet, P.3
  • 92
    • 63249113825 scopus 로고    scopus 로고
    • Successful treatment with B-cell depleting therapy for refractory systemic onset juvenile idiopathic arthritis: A case report
    • Kasher-Meron M, Uziel Y, Amital H. Successful treatment with B-cell depleting therapy for refractory systemic onset juvenile idiopathic arthritis: A case report. Rheumatology (Oxford) 2009;48:445-6
    • (2009) Rheumatology (Oxford) , vol.48 , pp. 445-446
    • Kasher-Meron, M.1    Uziel, Y.2    Amital, H.3
  • 93
    • 65249153520 scopus 로고    scopus 로고
    • Rituximab therapy for refractory systemic-onset juvenile idiopathic arthritis
    • Narvaez J, Diaz-Torne C, Juanola X, et al. Rituximab therapy for refractory systemic-onset juvenile idiopathic arthritis. Ann Rheum Dis 2009;68:607-8
    • (2009) Ann Rheum Dis , vol.68 , pp. 607-608
    • Narvaez, J.1    Diaz-Torne, C.2    Juanola, X.3
  • 94
    • 70350141204 scopus 로고    scopus 로고
    • Rituximab therapy produced rapid and sustained clinical improvement in a patient with systemic onset juvenile idiopathic arthritis refractory to TNF alpha antagonists
    • Feito JG, Pereda CA. Rituximab therapy produced rapid and sustained clinical improvement in a patient with systemic onset juvenile idiopathic arthritis refractory to TNF alpha antagonists. J Clin Rheumatol 2009;15:363-5
    • (2009) J Clin Rheumatol , vol.15 , pp. 363-365
    • Feito, J.G.1    Pereda, C.A.2
  • 95
    • 33746551122 scopus 로고    scopus 로고
    • Successful treatment of refractory adult onset still's disease with rituximab
    • Ahmadi-Simab K, Lamprecht P, Jankowiak C, Gross WL. Successful treatment of refractory adult onset still's disease with rituximab. Ann Rheum Dis 2006;65:1117-18
    • (2006) Ann Rheum Dis , vol.65 , pp. 1117-1118
    • Ahmadi-Simab, K.1    Lamprecht, P.2    Jankowiak, C.3    Gross, W.L.4
  • 96
    • 34447523762 scopus 로고    scopus 로고
    • Specific gene expression profiles in systemic juvenile idiopathic arthritis
    • Ogilvie EM, Khan A, Hubank M, et al. Specific gene expression profiles in systemic juvenile idiopathic arthritis. Arthritis Rheum 2007;56:1954-65
    • (2007) Arthritis Rheum , vol.56 , pp. 1954-1965
    • Ogilvie, E.M.1    Khan, A.2    Hubank, M.3
  • 97
    • 33750214515 scopus 로고    scopus 로고
    • Successful treatment of refractory polyarticular juvenile idiopathic arthritis with rituximab
    • Kuek A, Hazleman BL, Gaston JH, Ostor AJ. Successful treatment of refractory polyarticular juvenile idiopathic arthritis with rituximab. Rheumatology (Oxford) 2006;45:1448-9
    • (2006) Rheumatology (Oxford) , vol.45 , pp. 1448-1449
    • Kuek, A.1    Hazleman, B.L.2    Gaston, J.H.3    Ostor, A.J.4
  • 98
    • 75649148242 scopus 로고    scopus 로고
    • Phenotypic and functional characterization of switch memory B cells from patients with oligoarticular juvenile idiopathic arthritis
    • Corcione A, Ferlito F, Gattorno M, et al. Phenotypic and functional characterization of switch memory B cells from patients with oligoarticular juvenile idiopathic arthritis. Arthritis Res Ther 2009;11:R150
    • (2009) Arthritis Res Ther , vol.11
    • Corcione, A.1    Ferlito, F.2    Gattorno, M.3
  • 99
    • 33846706571 scopus 로고    scopus 로고
    • Lymphoid neogenesis in juvenile idiopathic arthritis correlates with ANA positivity and plasma cells infiltration
    • Gregorio A, Gambini C, Gerloni V, et al. Lymphoid neogenesis in juvenile idiopathic arthritis correlates with ANA positivity and plasma cells infiltration. Rheumatology (Oxford) 2007;46:308-13
    • (2007) Rheumatology (Oxford) , vol.46 , pp. 308-313
    • Gregorio, A.1    Gambini, C.2    Gerloni, V.3
  • 100
    • 47249157224 scopus 로고    scopus 로고
    • Therapeutic targeting of Janus kinases
    • Pesu M, Laurence A, Kishore N, et al. Therapeutic targeting of Janus kinases. Immunol Rev 2008;223:132-42
    • (2008) Immunol Rev , vol.223 , pp. 132-142
    • Pesu, M.1    Laurence, A.2    Kishore, N.3
  • 101
    • 77956165442 scopus 로고    scopus 로고
    • Inhibition of JAK kinases in patients with rheumatoid arthritis: Scientific rationale and clinical outcomes
    • Riese RJ, Krishnaswami S, Kremer J. Inhibition of JAK kinases in patients with rheumatoid arthritis: Scientific rationale and clinical outcomes. Best Pract Res Clin Rheumatol 2010;24:513-26
    • (2010) Best Pract Res Clin Rheumatol , vol.24 , pp. 513-526
    • Riese, R.J.1    Krishnaswami, S.2    Kremer, J.3
  • 102
    • 80051918343 scopus 로고    scopus 로고
    • Tasocitinib (CP-690,550), an orally available Janus kinase inhibitor, exhibits sustained safety and efficacy in the treatment of rheumatoid arthritis over 24 months
    • Connel CA, Riese R, Wood S. Tasocitinib (CP-690,550), an orally available Janus kinase inhibitor, exhibits sustained safety and efficacy in the treatment of rheumatoid arthritis over 24 months. Arthritis Rheum 2010;10(S):S473
    • (2010) Arthritis Rheum , vol.10 , Issue.S
    • Connel, C.A.1    Riese, R.2    Wood, S.3
  • 103
    • 67650093218 scopus 로고    scopus 로고
    • The safety and efficacy of a JAK inhibitor in patients with active rheumatoid arthritis: Results of a double-blind, placebo-controlled phase IIa trial of three dosage levels of CP-690,550 versus placebo
    • Kremer JM, Bloom BJ, Breedveld FC, et al. The safety and efficacy of a JAK inhibitor in patients with active rheumatoid arthritis: Results of a double-blind, placebo-controlled phase IIa trial of three dosage levels of CP-690,550 versus placebo. Arthritis Rheum 2009;60:1895-905
    • (2009) Arthritis Rheum , vol.60 , pp. 1895-1905
    • Kremer, J.M.1    Bloom, B.J.2    Breedveld, F.C.3
  • 104
    • 55849114400 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis with a Syk kinase inhibitor: A twelve-week, randomized, placebo-controlled trial
    • Weinblatt ME, Kavanaugh A, Burgos-Vargas R, et al. Treatment of rheumatoid arthritis with a Syk kinase inhibitor: A twelve-week, randomized, placebo-controlled trial. Arthritis Rheum 2008;58:3309-18
    • (2008) Arthritis Rheum , vol.58 , pp. 3309-3318
    • Weinblatt, M.E.1    Kavanaugh, A.2    Burgos-Vargas, R.3
  • 105
    • 77957333252 scopus 로고    scopus 로고
    • An oral spleen tyrosine kinase (Syk) inhibitor for rheumatoid arthritis
    • Weinblatt ME, Kavanaugh A, Genovese MC, et al. An oral spleen tyrosine kinase (Syk) inhibitor for rheumatoid arthritis. N Engl J Med 2010;363:1303-12
    • (2010) N Engl J Med , vol.363 , pp. 1303-1312
    • Weinblatt, M.E.1    Kavanaugh, A.2    Genovese, M.C.3
  • 106
    • 78650294662 scopus 로고    scopus 로고
    • An oral syk kinase inhibitor in the treatment of rheumatoid arthritis: A 3 month randomized placebo controlled phase 2 study in patients with active RA who had failed biologic agents
    • published online doi:10.1002/art.30114 [doi]
    • Genovese MC, Kavanaugh A, Weinblatt ME, et al. An oral syk kinase inhibitor in the treatment of rheumatoid arthritis: A 3 month randomized placebo controlled phase 2 study in patients with active RA who had failed biologic agents. Arthritis Rheum 2010; published online, doi:10.1002/art.30114 [doi]
    • (2010) Arthritis Rheum
    • Genovese, M.C.1    Kavanaugh, A.2    Weinblatt, M.E.3
  • 107
    • 34548448017 scopus 로고    scopus 로고
    • Erosive arthritis
    • Schett G. Erosive arthritis. Arthritis Res Ther 2007;9(Suppl 1):S2
    • (2007) Arthritis Res Ther , vol.9 , Issue.SUPPL. 1
    • Schett, G.1
  • 108
    • 2342598382 scopus 로고    scopus 로고
    • Osteoprotegerin (OPG)/RANK-L system in juvenile idiopathic arthritis: Is there a potential modulating role for OPG/ RANK-L in bone injury?
    • Masi L, Simonini G, Piscitelli E, et al. Osteoprotegerin (OPG)/RANK-L system in juvenile idiopathic arthritis: Is there a potential modulating role for OPG/ RANK-L in bone injury? J Rheumatol 2004;31:986-91
    • (2004) J Rheumatol , vol.31 , pp. 986-991
    • Masi, L.1    Simonini, G.2    Piscitelli, E.3
  • 109
    • 0345700823 scopus 로고    scopus 로고
    • Synovial dendritic cells in juvenile idiopathic arthritis (JIA) express receptor activator of NF-kappaB (RANK)
    • Varsani H, Patel A, van KY, et al. Synovial dendritic cells in juvenile idiopathic arthritis (JIA) express receptor activator of NF-kappaB (RANK). Rheumatology (Oxford) 2003;42:583-90
    • (2003) Rheumatology (Oxford) , vol.42 , pp. 583-590
    • Varsani, H.1    Patel, A.2    Van, K.Y.3
  • 110
    • 56249099021 scopus 로고    scopus 로고
    • Osteoprotegerin/RANKL system imbalance in active polyarticular-onset juvenile idiopathic arthritis: A bone damage biomarker?
    • Spelling P, Bonfa E, Caparbo VF, Pereira RM. Osteoprotegerin/RANKL system imbalance in active polyarticular-onset juvenile idiopathic arthritis: A bone damage biomarker? Scand J Rheumatol 2008;37:439-44
    • (2008) Scand J Rheumatol , vol.37 , pp. 439-444
    • Spelling, P.1    Bonfa, E.2    Caparbo, V.F.3    Pereira, R.M.4
  • 111
    • 41949119550 scopus 로고    scopus 로고
    • Elevated serum receptor activator of NFkappaB ligand (RANKL), osteoprotegerin (OPG), matrix metalloproteinase (MMP) 3, and ProMMP1 in patients with juvenile idiopathic arthritis
    • Sarma PK, Misra R, Aggarwal A. Elevated serum receptor activator of NFkappaB ligand (RANKL), osteoprotegerin (OPG), matrix metalloproteinase (MMP)3, and ProMMP1 in patients with juvenile idiopathic arthritis. Clin Rheumatol 2008;27:289-94
    • (2008) Clin Rheumatol , vol.27 , pp. 289-294
    • Sarma, P.K.1    Misra, R.2    Aggarwal, A.3
  • 112
    • 77951565454 scopus 로고    scopus 로고
    • Effects of denosumab on bone mineral density and bone turnover in patients with rheumatoid arthritis receiving concurrent glucocorticoids or bisphosphonates
    • Dore RK, Cohen SB, Lane NE, et al. Effects of denosumab on bone mineral density and bone turnover in patients with rheumatoid arthritis receiving concurrent glucocorticoids or bisphosphonates. Ann Rheum Dis 2010;69:872-5
    • (2010) Ann Rheum Dis , vol.69 , pp. 872-875
    • Dore, R.K.1    Cohen, S.B.2    Lane, N.E.3
  • 113
    • 77950451127 scopus 로고    scopus 로고
    • Denosumab-mediated increase in hand bone mineral density associated with decreased progression of bone erosion in rheumatoid arthritis patients
    • Deodhar A, Dore RK, Mandel D, et al. Denosumab-mediated increase in hand bone mineral density associated with decreased progression of bone erosion in rheumatoid arthritis patients. Arthritis Care Res (Hoboken) 2010;62:569-74
    • (2010) Arthritis Care Res (Hoboken) , vol.62 , pp. 569-574
    • Deodhar, A.1    Dore, R.K.2    Mandel, D.3
  • 114
    • 43949139580 scopus 로고    scopus 로고
    • Denosumab treatment effects on structural damage, bone mineral density, and bone turnover in rheumatoid arthritis: A twelve-month, multicenter, randomized, double-blind, placebo-controlled, phase II clinical trial
    • Cohen SB, Dore RK, Lane NE, et al. Denosumab treatment effects on structural damage, bone mineral density, and bone turnover in rheumatoid arthritis: A twelve-month, multicenter, randomized, double-blind, placebo-controlled, phase II clinical trial. Arthritis Rheum 2008;58:1299-309
    • (2008) Arthritis Rheum , vol.58 , pp. 1299-1309
    • Cohen, S.B.1    Dore, R.K.2    Lane, N.E.3
  • 115
    • 77950422143 scopus 로고    scopus 로고
    • Denosumab prevents metacarpal shaft cortical bone loss in patients with erosive rheumatoid arthritis
    • Sharp JT, Tsuji W, Ory P, et al. Denosumab prevents metacarpal shaft cortical bone loss in patients with erosive rheumatoid arthritis. Arthritis Care Res (Hoboken) 2010;62:537-44
    • (2010) Arthritis Care Res (Hoboken) , vol.62 , pp. 537-544
    • Sharp, J.T.1    Tsuji, W.2    Ory, P.3
  • 116
    • 34547521058 scopus 로고    scopus 로고
    • Osteoclast-poor human osteopetrosis due to mutations in the gene encoding RANKL
    • Sobacchi C, Frattini A, Guerrini MM, et al. Osteoclast-poor human osteopetrosis due to mutations in the gene encoding RANKL. Nat Genet 2007;39:960-2
    • (2007) Nat Genet , vol.39 , pp. 960-962
    • Sobacchi, C.1    Frattini, A.2    Guerrini, M.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.