Elevated serum receptor activator of NFκB ligand (RANKL), osteoprotegerin (OPG), matrix metalloproteinase (MMP)3, and ProMMP1 in patients with juvenile idiopathic arthritis

Clinical Rheumatology

Volumn 27, Issue 3, 2008, Pages 289-294

  Sarma, Pradip Kumar ^a   Misra, Ramnath ^a   Aggarwal, Amita ^a  

^a SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Matrix metalloproteinases; Osteoprotegerin; Proteinases; Receptor activator of nuclear factor B; Tissue inhibitor of metalloproteinases

Indexed keywords

ETANERCEPT; HYDROXYCHLOROQUINE; INTERSTITIAL COLLAGENASE; LEFLUNOMIDE; METHOTREXATE; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; SALAZOSULFAPYRIDINE; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; BIOLOGICAL MARKER; TNFRSF11B PROTEIN, HUMAN; TNFSF11 PROTEIN, HUMAN; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ARTICLE; CHILD; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE DURATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; HUMAN; JOINT INJURY; JOINT SWELLING; JUVENILE RHEUMATOID ARTHRITIS; MAJOR CLINICAL STUDY; MALE; MORNING STIFFNESS; ONSET AGE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RHEUMATOID ARTHRITIS; VISUAL ANALOG SCALE; BLOOD; CASE CONTROL STUDY; CLASSIFICATION; HOSPITALIZATION; PATHOPHYSIOLOGY; PRESCHOOL CHILD;

ADOLESCENT; ADULT; ARTHRITIS, JUVENILE RHEUMATOID; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; MALE; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 3; OSTEOPROTEGERIN; RANK LIGAND; SEVERITY OF ILLNESS INDEX; TISSUE INHIBITOR OF METALLOPROTEINASE-1;

EID: 41949119550     PISSN: 07703198     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10067-007-0701-3     Document Type: Article

References (15)

1. CE Rabinovich 2000 Bone mineral status in juvenile rheumatoid arthritis J Rheumatol 27 34 37
2. P Aggarwal A Aggarwal S Gupta R Misra 2006 Osteopenia is common in adult male patients with active juvenile idiopathic arthritis J Rheumatol 33 1642 1645 16881120
3. LC Hofbauer AE Heufelder 2001 A role of osteoprotegerin and receptor activator of nuclear factor kB ligand in the pathogenesis and treatment of rheumatoid arthritis Arthritis Rheum 44 253 259 11229454 10.1002/1529- 0131(200102)44:2<253::AID-ANR41>3.0.CO;2-S 1:CAS:528:DC%2BD3MXitlCgtLk%3D (Pubitemid 32207017)
4. Masi Laura G Simonini E Piscitelli F Del Monte T Giani R Cimaz, et al. 2004 Osteoprotegerin (OPG)/RANK-L system in juvenile idiopathic arthritis: is there a potential modulating role for OPG/RANK-L in bone injury? J Rheumatol 31 986 991
5. MJ Green AK Gough J Devlin, et al. 2003 Serum MMP-3, MMP-1, and progression of joint damage in early rheumatoid arthritis Rheumatology (Oxford) 42 83 88 10.1093/rheumatology/keg037 1:CAS:528:DC%2BD3sXovFamsQ%3D%3D (Pubitemid 36131572)
6. C Ribbens B Andre JM Jaspar, et al. 2000 Matrix metalloproteinase-3 serum levels are correlated with disease activity and predict clinical response in rheumatoid arthritis J Rheumatol 27 888 893 10782811 1:CAS:528: DC%2BD3cXivFOrsb4%3D
7. Y Yoshihara H Nakamura K Obata, et al. 2000 Matrix metalloproteinases and tissue inhibitors of metalloproteinases in synovial fluids from patients with rheumatoid arthritis or osteoarthritis Ann Rheum Dis 59 455 461 10834863 10.1136/ard.59.6.455 1:CAS:528:DC%2BD3cXksVCktbw%3D (Pubitemid 30395603)
8. M Fiedorczyk PA Klimiuk S Sierakowski E Gindzienska-Sieskiewicz J Chwiecko 2006 Serum matrix metalloproteinases and tissue inhibitors of metalloproteinases in patients with early rheumatoid arthritis J Rheumatol 33 1523 1529 16881109 1:CAS:528:DC%2BD28Xpt1Oksbo%3D
9. M Gattorno S Vignola F Falcini F Sabatini A Buoncompagni G Simonini P Picco V Pistoia 2002 Serum and synovial fluid concentrations of matrix metalloproteinases 3 and its tissue inhibitor 1 in juvenile idiopathic arthritis J Rheumatol 29 826 831 11950028 1:CAS:528:DC%2BD38XjtFGltLk%3D (Pubitemid 34303880)
10. NJ Khawajal K Khawaja1 A Myers D Jones TE Cawston AD Rowan HE Foster 2005 Levels of matrix metalloproteinase (MMP)-1 in paired sera and synovial fluids of juvenile idiopathic arthritis patients: relationship to inflammatory activity, MMP-3 and tissue inhibitor of metalloproteinases-1 in a longitudinal study Rheumatology (Oxford) 44 1383 1389 10.1093/rheumatology/kei025 (Pubitemid 41631861)
11. RE Prttry TR Southwood P Manners, et al. 2004 International League of Associations for Rheumatology classification of juvenile idiopathic arthritis: second revision, Edmonton, 2001 J Rheumatol 31 390 392
12. A Lurati I Pontikaki B Teruzzi F Desiati V Gerloni M Gattinara R Cimaz F Fantini 2006 A comparison of response criteria to evaluate therapeutic response in patients with juvenile idiopathic arthritis treated with methotrexate and/or anti-tumor necrosis factor alpha agents Arthritis Rheum 54 5 1602 1607 16646003 10.1002/art.21784 1:CAS:528:DC%2BD28XlsFWjsro%3D
13. S Viola E Felici S Magni-Manzoni A Pistorio A Buoncompagni N Ruperto F Rossi M Bartoli A Martini A Ravelli 2005 Development and validation of a clinical index for assessment of long-term damage in juvenile idiopathic arthritis Arthritis Rheum 52 2092 2102 15986372 10.1002/art.21119 (Pubitemid 40994332)
14. M Ziolkowska A Kurowska A Radzikowska, et al. 2002 High levels of osteoprotegerin and soluble receptor activator of nuclear factor kappa B ligand in serum of rheumatoid arthritis patients and their normalization after anti-tumor necrosis factor alpha treatment Arthritis Rheum 46 1744 1753 12124857 10.1002/art.10388 1:CAS:528:DC%2BD38XmtFWgs78%3D (Pubitemid 34774505)
15. T Nakashima Y Kobayashi S Yamasaki, et al. 2000 Protein expression and functional difference of membrane-bound and soluble receptor activator of NF-kappaB ligand: modulation of the expression by osteotropic factors and cytokines Biochem Biophys Res Commun 275 768 775 10973797 10.1006/bbrc.2000.3379 1:CAS:528:DC%2BD3cXmtFGlsL8%3D (Pubitemid 30708235)