Transforming growth factor-β inhibits myocardial PPARγ expression in pressure overload-induced cardiac fibrosis and remodeling in mice

Journal of Hypertension

Volumn 29, Issue 9, 2011, Pages 1810-1819

  Gong, Kaizheng ^a,d   Chen, Yiu Fai ^a   Li, Peng ^a   Lucas, Jason A ^a   Hage, Fadi G ^a   Yang, Qinglin ^b   Nozell, Susan E ^c   Oparil, Suzanne ^a   Xing, Dongqi ^a  

^a University of Alabama at Birmingham   (United States)

^b Department of Nutrition Sciences ^*  (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d YANGZHOU UNIVERSITY   (China)

Author keywords

cardiac fibroblast; cardiac fibrosis; peroxisome proliferatoractivated receptor gamma; Smad; transforming growth factor

Indexed keywords

HISTONE DEACETYLASE 1; HISTONE H3; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FIBROBLAST; FIBROGENESIS; GENETIC TRANSCRIPTION; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEART VENTRICLE OVERLOAD; HEART VENTRICLE REMODELING; HISTONE ACETYLATION; INTRACELLULAR SIGNALING; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; STEADY STATE; WILD TYPE;

EID: 80051945454     PISSN: 02636352     EISSN: 14735598     Source Type: Journal    
DOI: 10.1097/HJH.0b013e32834a4d03     Document Type: Article

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