Development and validation of a ultra-high-performance liquid chromatography-UV method for the detection and quantification of erectile dysfunction drugs and some of their analogues found in counterfeit medicines

Journal of Chromatography A

Volumn 1218, Issue 37, 2011, Pages 6439-6447

  Sacré, Pierre Yves ^a,b   Deconinck, Eric ^a   Chiap, Patrice ^c   Crommen, Jacques ^b   Mansion, François ^b   Rozet, Eric ^b   Courselle, Patricia ^a   De Beer, Jacques O ^a  

^a SCIENTIFIC INSTITUTE OF PUBLIC HEALTH   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

Accuracy profiles; Analogues; Counterfeit drugs; Method validation; Phosphodiesterase type 5 inhibitors; UHPLC

Indexed keywords

ACCURACY PROFILES; ANALOGUES; COUNTERFEIT DRUGS; METHOD VALIDATIONS; PHOSPHODIESTERASES; UHPLC;

ACETONITRILE; AMMONIUM COMPOUNDS; ESTERS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHASE SEPARATION;

CRIME;

ACETILDENAFIL; ACETONITRILE; AMINOTADALAFIL; AMMONIUM FORMATE; DIMETHYLSILDENAFIL; HDYROXYACETILDENAFIL; PSEUDOVARDENAFIL; SILDENAFIL; TADALAFIL; TRANS TADALAFIL; UNCLASSIFIED DRUG; VARDENAFIL;

ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG STRUCTURE; INTERMETHOD COMPARISON; MASS SPECTROMETRY; PRIORITY JOURNAL; SEPARATION TECHNIQUE; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ULTRAVIOLET RADIATION; VALIDATION PROCESS;

ACETONITRILES; ANALYSIS OF VARIANCE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COUNTERFEIT DRUGS; LINEAR MODELS; PHOSPHODIESTERASE 5 INHIBITORS; PIPERAZINES; PURINES; REPRODUCIBILITY OF RESULTS; SPECTROPHOTOMETRY, ULTRAVIOLET; SULFONES;

EID: 80051883505     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2011.07.029     Document Type: Article

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