Screening of Indian aphrodisiac ayurvedic/herbal healthcare products for adulteration with sildenafil, tadalafil and/or vardenafil using LC/PDA and extracted ion LC-MS/TOF

Journal of Pharmaceutical and Biomedical Analysis

Volumn 52, Issue 3, 2010, Pages 406-409

  Savaliya, Akash A ^a   Shah, Ravi P ^a   Prasad, Bhagwat ^a   Singh, Saranjit ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Adulteration; Herbal formulations; LC MS TOF; PDE 5 inhibitors; Sildenafil; Tadalafil; Vardenafil

Indexed keywords

METHANOL; POTASSIUM DIHYDROGEN PHOSPHATE; SILDENAFIL; TADALAFIL; VARDENAFIL;

ACCURACY; ARTICLE; CENTRIFUGATION; CONTROLLED STUDY; DRUG FORMULATION; DRUG ISOLATION; EARLY DIAGNOSIS; HERBAL MEDICINE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL; QUANTITATIVE STUDY; TIME OF FLIGHT MASS SPECTROMETRY; ULTRAVIOLET RADIATION; VALIDATION STUDY;

APHRODISIACS; CARBOLINES; CHROMATOGRAPHY, LIQUID; DRUG CONTAMINATION; HUMANS; IMIDAZOLES; INDIA; MALE; MASS SPECTROMETRY; MEDICINE, AYURVEDIC; PHOSPHODIESTERASE INHIBITORS; PIPERAZINES; PLANT PREPARATIONS; PURINES; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SULFONES; TRIAZINES;

EID: 77649336879     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2009.05.021     Document Type: Article

References (32)

1. Au A.M., Ko R., Boo F.O., Hsu R., Perez G., and Yang Z. Bull. Environ. Contam. Toxicol. 65 (2000) 112-119
2. Ko R.J. N. Engl. J. Med. 339 (1998) 847-848
3. Lau K.K., Lai C.K., and Chan A.W. Hum. Exp. Toxicol. 19 (2000) 385-386
4. Wu M.S., Hong J.J., Lin J.L., Yang C.W., and Chien H.C. Nephrol. Dial. Transplant. 11 (1996) 867-870
5. Corbin J.D., and Francis S.H. J. Androl. 24 (2003) S38-S41
6. Rang H.P., Dale M.M., Ritter J.M., and Moore P.K. Pharmacology. fifth ed. (2003), Elsevier, New Delhi, India pp. 443-444
7. Blok-Tip L., Zomer B., Bakker F., Hartog K.D., Hamzink M., Ten Hove J., Vredenbregt M., and De Kaste D. Food Addit. Contam. 21 (2004) 737-748
8. Gratz S.R., Flurer C.L., and Wolnik K.A. J. Pharm. Biomed. Anal. 36 (2004) 525-533
9. Hou P., Zou P., Low M.Y., Chan E., and Koh H.L. Food Addit. Contam. 23 (2006) 870-875
10. Lai K.C., Liu Y.C., Tseng M.C., and Lin J.H. J. Food Drug Anal. 14 (2006) 19-23
11. Liang Q., Qu J., Luo G., and Wang Y. J. Pharm. Biomed. Anal. 40 (2006) 305-311
12. Mei C.L., Yi C.L., and Jer H.L. J. Food Drug Anal. 14 (2006) 260-264
13. Oh S.S., Zou P., Low M.Y., and Koh H.L. J. Toxicol. Environ. Health A 69 (2006) 1951-1958
14. Poon W.T., Lam Y.H., Lai C.K., Chan A.Y., and Mak T.W. J. Hong Kong Med. 13 (2007) 359-363
15. Reepmeyer J.C., and Woodruff J.T. J. Chromatogr. A 1125 (2006) 67-75
16. Reepmeyer J.C., and Woodruff J.T. J. Pharm. Biomed. Anal. 44 (2007) 887-893
17. Reepmeyer J.C., Woodruff J.T., and d'Avignon D.A. J. Pharm. Biomed. Anal. 43 (2007) 1615-1621
18. Shin M.H., Hong M.K., Kim W.S., Lee Y.J., and Jeoung Y.C. Food Addit. Contam. 20 (2003) 793-796
19. Venhuis B.J., Zomer G., and de Kaste D. J. Pharm. Biomed. Anal. 46 (2008) 814-817
20. Zou P., Hou P., Oh S.S.Y., Ge X., Bloodworth B.C., Low M.Y., and Koh H.L. J. Pharm. Biomed. Anal. 47 (2008) 255-259
21. Zou P., Hou P., Oh S.S.Y., Chong Y.M., Bloodworth B.C., Low M.Y., and Koh H.L. J. Pharm. Biomed. Anal. 47 (2008) 279-284
22. Zou P., Oh S.S., Hou P., Low M.Y., and Koh H.L. J. Chromatogr. A 1104 (2006) 113-122
23. Krishnaprasad R., Pillay V.V., Rajesh R.R., and Vishnupriya N. J. Indian Soc. Toxicol. 1 (2005) 20-25
24. Ernst E. Pharm. J. 275 (2005) 167-168
25. Singh S., Prasad B., Savaliya A.A., Shah R.P., Gohil V.M., and Kaur A. Trends Anal. Chem. 28 (2009) 13-28
26. ICH, Q2(R1), in: International Conference on Harmonisation, IFPMA, Geneva, 2005.
27. Eerkes A., Addison T., and Naidong W. J. Chromatogr. B 768 (2002) 277-284
28. Ramakrishna N.V.S., Vishwottam K.N., Puran S., Koteshwara M., Manoj S., Santosh M., Chidambara J., Wishu S., and Sumatha B. J. Chromatogr. B 809 (2004) 243-249
29. Zhong D., Xing J., Zhang S., and Sun L. Rapid Commun. Mass Spectrom. 16 (2002) 1836-1843
30. Zhu X., Xiao S., Chen B., Zhang F., Yao S., Wan Z., Yang D., and Han H. J. Chromatogr. A 1066 (2005) 89-95
31. Zou P., Hou P., Oh S.S., Low M., and Koh H. Rapid Commun. Mass Spectrom. 20 (2006) 3488-3490
32. Gratz S.R., Gamble B.M., and Flurer R.A. Rapid Commun. Mass Spectrom. 20 (2006) 2317-2327