Use of liquid chromatography-mass spectrometry and a hydrolytic technique for the detection and structure elucidation of a novel synthetic vardenafil designer drug added illegally to a "natural" herbal dietary supplement

Journal of Chromatography A

Volumn 1125, Issue 1, 2006, Pages 67-75

  Reepmeyer, John C ^a   Woodruff, Jeffrey T ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Designer drug; Dietary supplement; Erectile dysfunction; Herbal; Phosphodiesterase 5 inhibitor; Piperidenafil; Vardenafil

Indexed keywords

HYDROLYSIS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NUTRITION; PHOSPHORUS; PROTEINS;

DESIGNER DRUGS; DIETARY SUPPLEMENTS; ERECTILE DYSFUNCTION; HERBAL; PHOSPHODIESTERASE-5 INHIBITORS; PIPERIDENAFIL; VARDENAFIL;

DRUG PRODUCTS;

ACETILDENAFIL; DESIGNER DRUG; HERBACEOUS AGENT; HOMOSILDENAFIL; HYDROXYHOMOSILDENAFIL; PHOSPHODIESTERASE V INHIBITOR; PIPERIDENAFIL; SILDENAFIL; TADALAFIL; UNCLASSIFIED DRUG; VARDENAFIL;

ARTICLE; CALCULATION; COLLISIONALLY ACTIVATED DISSOCIATION; DIET SUPPLEMENTATION; DRUG CAPSULE; DRUG DETERMINATION; DRUG HYDROLYSIS; DRUG IDENTIFICATION; DRUG STRUCTURE; ERECTILE DYSFUNCTION; GAS CHROMATOGRAPHY; INTERNET; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL; SEXUAL FUNCTION; STRUCTURE ANALYSIS;

CHROMATOGRAPHY, LIQUID; DESIGNER DRUGS; DIETARY SUPPLEMENTS; HYDROLYSIS; IMIDAZOLES; MASS SPECTROMETRY; MOLECULAR STRUCTURE; PHOSPHODIESTERASE INHIBITORS; PIPERAZINES; PLANT PREPARATIONS; SPECTROPHOTOMETRY, ULTRAVIOLET; SULFONES; TRIAZINES;

EID: 33746706234     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2006.05.018     Document Type: Article

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