Killing hypoxic cell populations in a 3D tumor model with EtNBS-PDT

PLoS ONE

Volumn 6, Issue 8, 2011, Pages

  Evans, Conor L ^a   Abu Yousif, Adnan O ^a   Park, Yong Jin ^b   Klein, Oliver J ^a   Celli, Jonathan P ^a   Rizvi, Imran ^a   Zheng, Xiang ^a   Hasan, Tayyaba ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

5 ETHYLAMINO 9 DIETHYL AMINOBENZO[A]PHENOTHIAZINIUM CHLORIDE; PHOTOSENSITIZING AGENT; UNCLASSIFIED DRUG; 5 ETHYLAMINO 9 DIETHYLAMINOBENZO(A)PHENOTHIAZINIUM; 5-ETHYLAMINO-9-DIETHYLAMINOBENZO(A)PHENOTHIAZINIUM; CARBOPLATIN; PORPHYRIN; THIAZINE DERIVATIVE; VERTEPORFIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL DEATH; CELL KILLING; CELL POPULATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DISEASE SEVERITY; DRUG CYTOTOXICITY; FEMALE; HUMAN; HUMAN CELL; HYPOXIC CELL; IN VITRO STUDY; LIGHT IRRADIANCE; METASTASIS; MULTIPHOTON MICROSCOPY; OPTICAL COHERENCE TOMOGRAPHY; OVARY CANCER; PHOTODYNAMIC THERAPY; PHOTOTOXICITY; THERAPY EFFECT; THREE DIMENSIONAL IMAGING; TIME LAPSE IMAGING; TISSUE OXYGENATION; TUMOR MODEL; TUMOR RESISTANCE; BIOLOGICAL MODEL; CELL HYPOXIA; CELL SURVIVAL; DRUG EFFECT; DRUG RESISTANCE; DRUG SCREENING; LIGHT; NEOPLASM; PATHOLOGY; PHOTOCHEMOTHERAPY; RADIATION EXPOSURE; TREATMENT OUTCOME; TUMOR CELL LINE;

CARBOPLATIN; CELL DEATH; CELL HYPOXIA; CELL LINE, TUMOR; CELL SURVIVAL; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; LIGHT; MODELS, BIOLOGICAL; NEOPLASM METASTASIS; NEOPLASMS; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PORPHYRINS; THIAZINES; TREATMENT OUTCOME;

EID: 80051839527     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023434     Document Type: Article

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