-
1
-
-
0030972757
-
Current concepts in the treatment of articular cartilage defects
-
Minas T, Nehrer S. Current concepts in the treatment of articular cartilage defects. Orthopedics 1997; 20:525-538.
-
(1997)
Orthopedics
, vol.20
, pp. 525-538
-
-
Minas, T.1
Nehrer, S.2
-
2
-
-
0036083985
-
Articular cartilage repair: Basic science and clinical progress. A review of the current status and prospects
-
Hunziker EB. Articular cartilage repair: basic science and clinical progress. A review of the current status and prospects. Osteoarthritis Cartilage 2002; 10:432-463.
-
(2002)
Osteoarthritis Cartilage
, vol.10
, pp. 432-463
-
-
Hunziker, E.B.1
-
3
-
-
33749343814
-
Results after microfracture of full-thickness chondral defects in different compartments in the knee
-
Kreuz PC, Steinwachs MR, Erggelet C, et al. Results after microfracture of full-thickness chondral defects in different compartments in the knee. Osteoarthritis Cartilage 2006; 14:1119-1125.
-
(2006)
Osteoarthritis Cartilage
, vol.14
, pp. 1119-1125
-
-
Kreuz, P.C.1
Steinwachs, M.R.2
Erggelet, C.3
-
4
-
-
0028031550
-
Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation
-
Brittberg M, Lindahl A, Nilsson A, et al. Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. N Engl J Med 1994; 331:889-895.
-
(1994)
N Engl J Med
, vol.331
, pp. 889-895
-
-
Brittberg, M.1
Lindahl, A.2
Nilsson, A.3
-
5
-
-
0042635558
-
Articular cartilage engineering with autologous chondrocyte transplantation. A review of recent developments
-
Brittberg M, Peterson L, Sjogren-Jansson E, et al. Articular cartilage engineering with autologous chondrocyte transplantation. A review of recent developments. J Bone Joint Surg Am 2003; 85A (Suppl 3):109-115.
-
(2003)
J Bone Joint Surg Am
, vol.85 A
, Issue.SUPPL. 3
, pp. 109-115
-
-
Brittberg, M.1
Peterson, L.2
Sjogren-Jansson, E.3
-
6
-
-
0032199210
-
Chondrocyte implantation in the repair of chondral lesions of the knee: Economics and quality of life
-
Minas T. Chondrocyte implantation in the repair of chondral lesions of the knee: economics and quality of life. Am J Orthop 1998; 27:739-744.
-
(1998)
Am J Orthop
, vol.27
, pp. 739-744
-
-
Minas, T.1
-
8
-
-
0034018392
-
Two- to 9-year outcome after autologous chondrocyte transplantation of the knee
-
Peterson L, Minas T, Brittberg M, et al. Two- to 9-year outcome after autologous chondrocyte transplantation of the knee. Clin Orthop Rel Res 2000; 374:212-234.
-
(2000)
Clin Orthop Rel Res
, vol.374
, pp. 212-234
-
-
Peterson, L.1
Minas, T.2
Brittberg, M.3
-
9
-
-
7244220098
-
Indications and implementation of recommendations of the working group 'Tissue Regeneration and Tissue Substitutes' for autologous chondrocyte transplantation (ACT)
-
Behrens P, Bosch U, Bruns J, et al. Indications and implementation of recommendations of the working group 'Tissue Regeneration and Tissue Substitutes' for autologous chondrocyte transplantation (ACT). Z Orthop Ihre Grenzgeb 2004; 142:529-539.
-
(2004)
Z Orthop Ihre Grenzgeb
, vol.142
, pp. 529-539
-
-
Behrens, P.1
Bosch, U.2
Bruns, J.3
-
11
-
-
0037315539
-
Autologous chondrocyte implantation and osteochondral cylinder transplantation in cartilage repair of the knee joint. A prospective, comparative trial
-
Horas U, Pelinkovic D, Herr G, et al. Autologous chondrocyte implantation and osteochondral cylinder transplantation in cartilage repair of the knee joint. A prospective, comparative trial. J Bone Joint Surg Am 2003; 85A:185-192.
-
(2003)
J Bone Joint Surg Am
, vol.85 A
, pp. 185-192
-
-
Horas, U.1
Pelinkovic, D.2
Herr, G.3
-
12
-
-
10744225506
-
Autologous chondrocyte implantation compared with microfracture in the knee. A randomized trial
-
Knutsen G, Engebretsen L, Ludvigsen TC, et al. Autologous chondrocyte implantation compared with microfracture in the knee. A randomized trial. J Bone Joint Surg Am 2004; 86A:455-464.
-
(2004)
J Bone Joint Surg Am
, vol.86 A
, pp. 455-464
-
-
Knutsen, G.1
Engebretsen, L.2
Ludvigsen, T.C.3
-
13
-
-
29844449078
-
Autologous chondrocyte implantation: A systematic review
-
This overview on selected clinical cartilage repair studies addresses, beside outcome, also a possible conflict of interest of authors since many cartilage repair studies receive funding from companies
-
Ruano-Ravina A, Jato DM. Autologous chondrocyte implantation: a systematic review. Osteoarthritis Cartilage 2006; 14:47-51. This overview on selected clinical cartilage repair studies addresses, beside outcome, also a possible conflict of interest of authors since many cartilage repair studies receive funding from companies.
-
(2006)
Osteoarthritis Cartilage
, vol.14
, pp. 47-51
-
-
Ruano-Ravina, A.1
Jato, D.M.2
-
14
-
-
0037355664
-
A prospective, randomised comparison of autologous chondrocyte implantation versus mosaicplasty for osteochondral defects in the knee
-
Bentley G, Biant LC, Carrington RW, et al. A prospective, randomised comparison of autologous chondrocyte implantation versus mosaicplasty for osteochondral defects in the knee. J Bone Joint Surg Br 2003; 85:223-230.
-
(2003)
J Bone Joint Surg Br
, vol.85
, pp. 223-230
-
-
Bentley, G.1
Biant, L.C.2
Carrington, R.W.3
-
15
-
-
33644920939
-
Autologous cultured chondrocytes: Adverse events reported to the United States Food and Drug Administration
-
An overview on the most common adverse events reported in association with the Carticel ACT technique of Genzyme reflecting graft failure, delamination and tissue hypertrophy as the most common adverse events
-
Wood JJ, Malek MA, Frassica FJ, et al. Autologous cultured chondrocytes: adverse events reported to the United States Food and Drug Administration. J Bone Joint Surg Am 2006; 88:503-507. An overview on the most common adverse events reported in association with the Carticel ACT technique of Genzyme reflecting graft failure, delamination and tissue hypertrophy as the most common adverse events.
-
(2006)
J Bone Joint Surg Am
, vol.88
, pp. 503-507
-
-
Wood, J.J.1
Malek, M.A.2
Frassica, F.J.3
-
16
-
-
0038077280
-
Histological assessment of cartilage repair: A report by the Histology Endpoint Committee of the International Cartilage Repair Society (ICRS)
-
Mainil-Varlet P, Aigner T, Brittberg M, et al. Histological assessment of cartilage repair: a report by the Histology Endpoint Committee of the International Cartilage Repair Society (ICRS). J Bone Joint Surg Am 2003; 85A (Suppl 2):45-57.
-
(2003)
J Bone Joint Surg Am
, vol.85 A
, Issue.SUPPL. 2
, pp. 45-57
-
-
Mainil-Varlet, P.1
Aigner, T.2
Brittberg, M.3
-
17
-
-
0035148799
-
Matrix turnover in human cartilage repair tissue in autologous chondrocyte implantation
-
Roberts S, Hollander AP, Caterson B, et al. Matrix turnover in human cartilage repair tissue in autologous chondrocyte implantation. Arthritis Rheum 2001; 44:2586-2598.
-
(2001)
Arthritis Rheum
, vol.44
, pp. 2586-2598
-
-
Roberts, S.1
Hollander, A.P.2
Caterson, B.3
-
18
-
-
30444461215
-
Cartilage repair: Generations of autologous chondrocyte transplantation
-
Marlovits S, Zeller P, Singer P, et al. Cartilage repair: generations of autologous chondrocyte transplantation. Eur J Radiol 2006; 57:24-31.
-
(2006)
Eur J Radiol
, vol.57
, pp. 24-31
-
-
Marlovits, S.1
Zeller, P.2
Singer, P.3
-
19
-
-
0036326828
-
A cell-seeded biocomposite for cartilage repair
-
Russlies M, Behrens P, Wunsch L, et al. A cell-seeded biocomposite for cartilage repair. Ann Anat 2002; 184:317-323.
-
(2002)
Ann Anat
, vol.184
, pp. 317-323
-
-
Russlies, M.1
Behrens, P.2
Wunsch, L.3
-
20
-
-
0034918532
-
Transplantation of chondrocytes seeded on a hyaluronan derivative (hyaff-11) into cartilage defects in rabbits
-
Grigolo B, Roseti L, Fiorini M, et al. Transplantation of chondrocytes seeded on a hyaluronan derivative (hyaff-11) into cartilage defects in rabbits. Biomaterials 2001; 22:2417-2424.
-
(2001)
Biomaterials
, vol.22
, pp. 2417-2424
-
-
Grigolo, B.1
Roseti, L.2
Fiorini, M.3
-
21
-
-
18944373370
-
Autologous chondrocyte implantation versus matrix-induced autologous chondrocyte implantation for osteochondral defects of the knee: A prospective, randomised study
-
Bartlett W, Skinner JA, Gooding CR, et al. Autologous chondrocyte implantation versus matrix-induced autologous chondrocyte implantation for osteochondral defects of the knee: a prospective, randomised study. J Bone Joint Surg Br 2005; 87:640-645.
-
(2005)
J Bone Joint Surg Br
, vol.87
, pp. 640-645
-
-
Bartlett, W.1
Skinner, J.A.2
Gooding, C.R.3
-
22
-
-
0142151440
-
Autologous chondrocyte implantation for cartilage repair: Monitoring its success by magnetic resonance imaging and histology
-
Roberts S, McCall IW, Darby AJ, et al. Autologous chondrocyte implantation for cartilage repair: monitoring its success by magnetic resonance imaging and histology. Arthritis Res Ther 2003; 5:R60-R73.
-
(2003)
Arthritis Res Ther
, vol.5
-
-
Roberts, S.1
McCall, I.W.2
Darby, A.J.3
-
23
-
-
11844294603
-
Molecular and immunohistological characterization of human cartilage two years following autologous cell transplantation
-
Grigolo B, Roseti L, De Franceschi L, et al. Molecular and immunohistological characterization of human cartilage two years following autologous cell transplantation. J Bone Joint Surg Am 2005; 87:46-57.
-
(2005)
J Bone Joint Surg Am
, vol.87
, pp. 46-57
-
-
Grigolo, B.1
Roseti, L.2
De Franceschi, L.3
-
24
-
-
12344257714
-
Autologous chondrocyte implantation in knee joint: MR imaging and histologic features at 1-year follow-up
-
Tins BJ, McCall IW, Takahashi T, et al. Autologous chondrocyte implantation in knee joint: MR imaging and histologic features at 1-year follow-up. Radiology 2005; 234:501-508.
-
(2005)
Radiology
, vol.234
, pp. 501-508
-
-
Tins, B.J.1
McCall, I.W.2
Takahashi, T.3
-
25
-
-
0036295210
-
Molecular analysis of expansion, differentiation, and growth factor treatment of human chondrocytes identifies differentiation markers and growth-related genes
-
Benz K, Breit S, Lukoschek M, et al. Molecular analysis of expansion, differentiation, and growth factor treatment of human chondrocytes identifies differentiation markers and growth-related genes. Biochem Biophys Res Commun 2002; 293:284-292.
-
(2002)
Biochem Biophys Res Commun
, vol.293
, pp. 284-292
-
-
Benz, K.1
Breit, S.2
Lukoschek, M.3
-
26
-
-
0034945018
-
Molecular markers predictive of the capacity of expanded human articular chondrocytes to form stable cartilage in vivo
-
Dell'Accio F, De Bari C, Luyten FP. Molecular markers predictive of the capacity of expanded human articular chondrocytes to form stable cartilage in vivo. Arthritis Rheum 2001; 44:1608-1619.
-
(2001)
Arthritis Rheum
, vol.44
, pp. 1608-1619
-
-
Dell'Accio, F.1
De Bari, C.2
Luyten, F.P.3
-
27
-
-
20444429578
-
Adult mesenchymal stem cells: Characterization, differentiation, and application in cell and gene therapy
-
Baksh D, Song L, Tuan RS. Adult mesenchymal stem cells: characterization, differentiation, and application in cell and gene therapy. J Cell Mol Med 2004; 8:301-316.
-
(2004)
J Cell Mol Med
, vol.8
, pp. 301-316
-
-
Baksh, D.1
Song, L.2
Tuan, R.S.3
-
28
-
-
0031817577
-
In vitro chondrogenesis of bone marrow-derived mesenchymal progenitor cells
-
Johnstone B, Hering TM, Caplan AI, et al. In vitro chondrogenesis of bone marrow-derived mesenchymal progenitor cells. Exp Cell Res 1998; 238:265-272.
-
(1998)
Exp Cell Res
, vol.238
, pp. 265-272
-
-
Johnstone, B.1
Hering, T.M.2
Caplan, A.I.3
-
29
-
-
0037331189
-
Cartilage-like gene expression in differentiated human stem cell spheroids: A comparison of bone marrow-derived and adipose tissue-derived stromal cells
-
Winter A, Breit S, Parsch D, et al. Cartilage-like gene expression in differentiated human stem cell spheroids: a comparison of bone marrow-derived and adipose tissue-derived stromal cells. Arthritis Rheum 2003; 48:418-429.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 418-429
-
-
Winter, A.1
Breit, S.2
Parsch, D.3
-
30
-
-
23644456193
-
Comparison of human stem cells derived from various mesenchymal tissues: Superiority of synovium as a cell source
-
Sakaguchi Y, Sekiya I, Yagishita K, et al. Comparison of human stem cells derived from various mesenchymal tissues: superiority of synovium as a cell source. Arthritis Rheum 2005; 52:2521-2529.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 2521-2529
-
-
Sakaguchi, Y.1
Sekiya, I.2
Yagishita, K.3
-
31
-
-
34247587579
-
-
Hennig T, Lorenz H, Thiel A, et al. Reduced chondrogenic potential of adipose tissue derived stromal cells correlates with an altered TGFbeta receptor and BMP profile and is overcome by BMP-6. J Cell Physiol 2007; 211:682-691. A comprehensive analysis on expression of growth factors of the TGF-β superfamily and their receptors by human MSCs from bone marrow and adipose tissue, and the effect of 17 growth factors and combinations of growth factors on the success of in-vitro chondrogenesis.
-
Hennig T, Lorenz H, Thiel A, et al. Reduced chondrogenic potential of adipose tissue derived stromal cells correlates with an altered TGFbeta receptor and BMP profile and is overcome by BMP-6. J Cell Physiol 2007; 211:682-691. A comprehensive analysis on expression of growth factors of the TGF-β superfamily and their receptors by human MSCs from bone marrow and adipose tissue, and the effect of 17 growth factors and combinations of growth factors on the success of in-vitro chondrogenesis.
-
-
-
-
32
-
-
33646367147
-
Potent induction of chondrocytic differentiation of human adipose-derived adult stem cells by bone morphogenetic protein 6
-
Estes BT, Wu AW, Guilak F. Potent induction of chondrocytic differentiation of human adipose-derived adult stem cells by bone morphogenetic protein 6. Arthritis Rheum 2006; 54:1222-1232.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 1222-1232
-
-
Estes, B.T.1
Wu, A.W.2
Guilak, F.3
-
33
-
-
0036845282
-
Replicative aging of human articular chondrocytes during ex vivo expansion
-
Parsch D, Brummendorf TH, Richter W, et al. Replicative aging of human articular chondrocytes during ex vivo expansion. Arthritis Rheum 2002; 46:2911-2916.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 2911-2916
-
-
Parsch, D.1
Brummendorf, T.H.2
Richter, W.3
-
34
-
-
0842330317
-
Telomere length and telomerase activity during expansion and differentiation of human mesenchymal stem cells and chondrocytes
-
Parsch D, Fellenberg J, Brummendorf TH, et al. Telomere length and telomerase activity during expansion and differentiation of human mesenchymal stem cells and chondrocytes. J Mol Med 2004; 82:49-55.
-
(2004)
J Mol Med
, vol.82
, pp. 49-55
-
-
Parsch, D.1
Fellenberg, J.2
Brummendorf, T.H.3
-
35
-
-
33750515870
-
Platelet-rich plasma improves expansion of human mesenchymal stem cells and retains differentiation capacity and in vivo bone formation in calcium phosphate ceramics
-
Vogel JP, Szalay K, Geiger F, et al. Platelet-rich plasma improves expansion of human mesenchymal stem cells and retains differentiation capacity and in vivo bone formation in calcium phosphate ceramics. Platelets 2006; 17:462-469.
-
(2006)
Platelets
, vol.17
, pp. 462-469
-
-
Vogel, J.P.1
Szalay, K.2
Geiger, F.3
-
36
-
-
0036184589
-
Human autologous culture expanded bone marrow mesenchymal cell transplantation for repair of cartilage defects in osteoarthritic knees
-
Wakitani S, Imoto K, Yamamoto T, et al. Human autologous culture expanded bone marrow mesenchymal cell transplantation for repair of cartilage defects in osteoarthritic knees. Osteoarthritis Cartilage 2002; 10:199-206.
-
(2002)
Osteoarthritis Cartilage
, vol.10
, pp. 199-206
-
-
Wakitani, S.1
Imoto, K.2
Yamamoto, T.3
-
37
-
-
0035882056
-
Chondrogenic differentiation of mesenchymal stem cells from bone marrow: Differentiation-dependent gene expression of matrix components
-
Barry F, Boynton RE, Liu B, et al. Chondrogenic differentiation of mesenchymal stem cells from bone marrow: differentiation-dependent gene expression of matrix components. Exp Cell Res 2001; 268:189-200.
-
(2001)
Exp Cell Res
, vol.268
, pp. 189-200
-
-
Barry, F.1
Boynton, R.E.2
Liu, B.3
-
38
-
-
15544381999
-
Induction of intervertebral disc-like cells from adult mesenchymal stem cells
-
Steck E, Bertram H, Abel R, et al. Induction of intervertebral disc-like cells from adult mesenchymal stem cells. Stem Cells 2005; 23:403-411.
-
(2005)
Stem Cells
, vol.23
, pp. 403-411
-
-
Steck, E.1
Bertram, H.2
Abel, R.3
-
39
-
-
30544449685
-
Chondrogenic differentiation and functional maturation of bovine mesenchymal stem cells in long-term agarose culture
-
Mauck RL, Yuan X, Tuan RS. Chondrogenic differentiation and functional maturation of bovine mesenchymal stem cells in long-term agarose culture. Osteoarthritis Cartilage 2006; 14:179-189.
-
(2006)
Osteoarthritis Cartilage
, vol.14
, pp. 179-189
-
-
Mauck, R.L.1
Yuan, X.2
Tuan, R.S.3
-
40
-
-
22544433139
-
Detailed examination of cartilage formation and endochondral ossification using human mesenchymal stem cells
-
Ichinose S, Yamagata K, Sekiya I, et al. Detailed examination of cartilage formation and endochondral ossification using human mesenchymal stem cells. Clin Exp Pharmacol Physiol 2005; 32:561-570.
-
(2005)
Clin Exp Pharmacol Physiol
, vol.32
, pp. 561-570
-
-
Ichinose, S.1
Yamagata, K.2
Sekiya, I.3
-
41
-
-
28944448291
-
The effect of glow discharge plasma surface modification of polymers on the osteogenic differentiation of committed human mesenchymal stem cells
-
Mwale F, Wang HT, Nelea V, et al. The effect of glow discharge plasma surface modification of polymers on the osteogenic differentiation of committed human mesenchymal stem cells. Biomaterials 2006; 27:2258-2264.
-
(2006)
Biomaterials
, vol.27
, pp. 2258-2264
-
-
Mwale, F.1
Wang, H.T.2
Nelea, V.3
-
42
-
-
33750321974
-
-
Pelttari K, Winter A, Steck E, et al. Premature induction of hypertrophy during in vitro chondrogenesis of human mesenchymal stem cells correlates with calcification and vascular invasion after ectopic transplantation in SCID mice. Arthritis Rheum 2006; 54:3254-3266. This study provides evidence that common protocols for in-vitro chondrogenesis of MSCs induce a differentiation program similar to endochondral bone formation and lead to transient cartilage rather than stable articular chondrocytes, which are resistant to hypertrophy in culture.
-
Pelttari K, Winter A, Steck E, et al. Premature induction of hypertrophy during in vitro chondrogenesis of human mesenchymal stem cells correlates with calcification and vascular invasion after ectopic transplantation in SCID mice. Arthritis Rheum 2006; 54:3254-3266. This study provides evidence that common protocols for in-vitro chondrogenesis of MSCs induce a differentiation program similar to endochondral bone formation and lead to transient cartilage rather than stable articular chondrocytes, which are resistant to hypertrophy in culture.
-
-
-
-
43
-
-
4644318980
-
Cyclic, mechanical compression enhances chondrogenesis of mesenchymal progenitor cells in tissue engineering scaffolds
-
Angele P, Schumann D, Angele M, et al. Cyclic, mechanical compression enhances chondrogenesis of mesenchymal progenitor cells in tissue engineering scaffolds. Biorheology 2004; 41:335-346.
-
(2004)
Biorheology
, vol.41
, pp. 335-346
-
-
Angele, P.1
Schumann, D.2
Angele, M.3
-
44
-
-
33745437125
-
Mechanobiological conditioning of stem cells for cartilage tissue engineering
-
Schumann D, Kujat R, Nerlich M, et al. Mechanobiological conditioning of stem cells for cartilage tissue engineering. Biomed Mater Eng 2006; 16:S37-S52.
-
(2006)
Biomed Mater Eng
, vol.16
-
-
Schumann, D.1
Kujat, R.2
Nerlich, M.3
-
45
-
-
33845412455
-
Regulation of cartilaginous ECM gene transcription by chondrocytes and MSCs in 3D culture in response to dynamic loading
-
Mauck RL, Byers BA, Yuan X, et al. Regulation of cartilaginous ECM gene transcription by chondrocytes and MSCs in 3D culture in response to dynamic loading. Biomech Model Mechanobiol 2007; 6:113-125.
-
(2007)
Biomech Model Mechanobiol
, vol.6
, pp. 113-125
-
-
Mauck, R.L.1
Byers, B.A.2
Yuan, X.3
|