Aminopyridines correct early dysfunction and delay neurodegeneration in a mouse model of spinocerebellar ataxia type

Journal of Neuroscience

Volumn 31, Issue 33, 2011, Pages 11795-11807

  Hourez, Raphael ^a,d   Servais, Laurent ^a,b,e   Orduz, David ^a   Gall, David ^a   Millard, Isabelle ^a   de Kerchove d'Exaerde, Alban ^a   Cheron, Guy ^b   Orr, Harry T ^c   Pandolfo, Massimo ^a   Schiffmann, Serge N ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b UNIVERSITY OF MONS   (Belgium)

^c UNIVERSITY OF MINNESOTA   (United States)

^d LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^e PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

3,4 DIAMINOPYRIDINE; 4 AMINOPYRIDINE; AMINOPYRIDINE DERIVATIVE; BRAIN DERIVED NEUROTROPHIC FACTOR; GLUTAMIC ACID; GROWTH FACTOR; POTASSIUM; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL KV4.3; SHAL POTASSIUM CHANNEL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASYMPTOMATIC DISEASE; CONTROLLED STUDY; DISEASE MODEL; ELECTRIC ACTIVITY; IN VIVO STUDY; LOCOMOTION; MOTOR DYSFUNCTION; MOUSE; NERVE CELL STIMULATION; NERVE DEGENERATION; NEUROPROTECTION; NEUROTRANSMISSION; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; PURKINJE CELL; SPINOCEREBELLAR ATAXIA TYPE 1; SPINOCEREBELLAR DEGENERATION; SYNAPSE; TISSUE SECTION;

ACTION POTENTIALS; AMINOPYRIDINES; ANIMALS; CONDITIONING, EYELID; DISEASE MODELS, ANIMAL; MICE; MICE, TRANSGENIC; MOTOR SKILLS DISORDERS; NERVE DEGENERATION; NEUROPROTECTIVE AGENTS; SPINOCEREBELLAR ATAXIAS; TIME FACTORS;

EID: 80051770615     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0905-11.2011     Document Type: Article

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