Sub-lytic C5b-9 induces functional changes in retinal pigment epithelial cells consistent with age-related macular degeneration

Eye

Volumn 25, Issue 8, 2011, Pages 1074-1082

  Lueck, K ^a   Wasmuth, S ^a   Williams, J ^b   Hughes, T R ^c   Morgan, B P ^c   Lommatzsch, A ^a   Greenwood, J ^b   Moss, S E ^b   Pauleikhoff, D ^a  

^a ST FRANZISKUS HOSPITAL   (Germany)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

age related macular degeneration; complement; membrane attack complex; retinal pigment epithelial cells

Indexed keywords

COMPLEMENT MEMBRANE ATTACK COMPLEX; GELATINASE A; GELATINASE B; INTERLEUKIN 6; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; VASCULOTROPIN; VITRONECTIN;

ARTICLE; CELL DEATH; CELL VIABILITY; COMPLEMENT ACTIVATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MICROENVIRONMENT; PIGMENT EPITHELIUM; RETINA MACULA AGE RELATED DEGENERATION; WESTERN BLOTTING; ZYMOGRAPHY;

EID: 80051727391     PISSN: 0950222X     EISSN: 14765454     Source Type: Journal    
DOI: 10.1038/eye.2011.109     Document Type: Article

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