The pathologic effect of a novel neomorphic Fgf9 Y162C allele is restricted to decreased vision and retarded lens growth

PLoS ONE

Volumn 6, Issue 8, 2011, Pages

  Puk, Oliver ^a   Möller, Gabriele ^a   Geerlof, Arie ^a   Krowiorz, Kathrin ^a   Ahmad, Nafees ^a   Wagner, Sibylle ^a   Adamski, Jerzy ^a,b   de Angelis, Martin Hrabé ^a,b   Graw, Jochen ^a  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CONNEXIN 46; ETHYLNITROSOUREA; FIBROBLAST GROWTH FACTOR 9; HEPARIN;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL GROWTH; CHROMOSOME 14; CONTROLLED STUDY; ELECTRORETINOGRAPHY; EYE DEVELOPMENT; FEMALE; FGF9 GENE; GENE; GENE DOSAGE; GENE EXPRESSION; GENE FUNCTION; GENE SEQUENCE; GENETIC LINKAGE; GJA3 GENE; IFT88 GENE; LENS DISEASE; LENS FIBER; MALE; MALE TO FEMALE TRANSSEXUAL; MICROPHAKIA; MISSENSE MUTATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN STRUCTURE; SEQUENCE ANALYSIS; SKELETON MALFORMATION; VISUAL IMPAIRMENT; AMINO ACID SEQUENCE; ANIMAL; BINDING COMPETITION; C3H MOUSE; C57BL MOUSE; CATARACT; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; GENOTYPE; GROWTH, DEVELOPMENT AND AGING; HAPLOTYPE; LENS; METABOLISM; MOLECULAR GENETICS; MOUSE MUTANT; PRENATAL DEVELOPMENT; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; VISION; VISUAL ACUITY;

ALLELES; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BINDING, COMPETITIVE; CATARACT; FEMALE; FIBROBLAST GROWTH FACTOR 9; GENOTYPE; HAPLOTYPES; HEPARIN; LENS, CRYSTALLINE; MALE; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; VISION, OCULAR; VISUAL ACUITY;

EID: 80051723933     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023678     Document Type: Article

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