메뉴 건너뛰기




Volumn 151, Issue 2, 2000, Pages 169-179

Inhibition of carcinogen-induced rat mammary tumor growth and other estrogen-dependent responses by symmetrical dihalo-substituted analogs of diindolylmethane

Author keywords

Ah receptor; Antitumorigenic; Dihalodims

Indexed keywords

4,4' DICHLORO 3,3' DIINDOLYLMETHANE; 5,5' DIBROMO 3,3' DIINDOLYLMETHANE; 5,5' DICHLORO 2,2' DIMETHYL 3,3' DIINDOLYLMETHANE; 5,5' DICHLORO 3,3' DIINDOLYLMETHANE; 5,5' DIFLUORO 3,3' DIINDOLYLMETHANE; 6,6' DICHLORO 3,3' DIINDOLYLMETHANE; CARCINOGEN; DIMETHYLBENZ[A]ANTHRACENE; ESTRADIOL; INDOLE DERIVATIVE; PROGESTERONE RECEPTOR; UNCLASSIFIED DRUG;

EID: 0034646769     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(99)00406-1     Document Type: Article
Times cited : (64)

References (34)
  • 1
    • 0028132860 scopus 로고
    • Steroid hormones and risk of breast cancer
    • Hulka B.S., Liu E.T., Lininger R.A. Steroid hormones and risk of breast cancer. Cancer. 74:1994;1111-1124.
    • (1994) Cancer , vol.74 , pp. 1111-1124
    • Hulka, B.S.1    Liu, E.T.2    Lininger, R.A.3
  • 2
    • 0030986245 scopus 로고    scopus 로고
    • Hormone-associated cancer: Mechanistic similarities between human breast cancer and estrogen-induced kidney carcinogenesis in hamsters
    • Liehr J.G. Hormone-associated cancer: mechanistic similarities between human breast cancer and estrogen-induced kidney carcinogenesis in hamsters. Environ. Health Perspect. 105:1997;565-569.
    • (1997) Environ. Health Perspect. , vol.105 , pp. 565-569
    • Liehr, J.G.1
  • 3
    • 0025223739 scopus 로고
    • Estrogen carcinogenesis in hamster tissues: A critical review
    • Li J.J., Li S.A. Estrogen carcinogenesis in hamster tissues: a critical review. Endocr. Rev. 11:1990;524-531.
    • (1990) Endocr. Rev. , vol.11 , pp. 524-531
    • Li, J.J.1    Li, S.A.2
  • 4
    • 0025373464 scopus 로고
    • Genotoxic effects of estrogens
    • Liehr J.G. Genotoxic effects of estrogens. Mutat. Res. 238:1990;269-276.
    • (1990) Mutat. Res. , vol.238 , pp. 269-276
    • Liehr, J.G.1
  • 5
    • 0022346543 scopus 로고
    • Estradiol 16α-hydroxylation in the mouse correlate with mammary tumor incidence and presence of murine mammary tumor virus: A possible model for the hormonal etiology of breast cancer in humans
    • Bradlow H.L., Hershcopf R.J., Martucci C.P., Fishman J. Estradiol 16α-hydroxylation in the mouse correlate with mammary tumor incidence and presence of murine mammary tumor virus: a possible model for the hormonal etiology of breast cancer in humans. Proc. Natl. Acad. Sci. USA. 82:1985;6295-6299.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 6295-6299
    • Bradlow, H.L.1    Hershcopf, R.J.2    Martucci, C.P.3    Fishman, J.4
  • 6
    • 0343178292 scopus 로고
    • Covalent binding of the endogenouse estrogen 16α-hydroxyestrone to estradiol receptor in human breast cancer cells: Characterization and intranuclear localization
    • Swaneck G.E., Fishman J. Covalent binding of the endogenouse estrogen 16α-hydroxyestrone to estradiol receptor in human breast cancer cells: characterization and intranuclear localization. Proc. Natl. Acad. Sci. USA. 85:1988;7831-7835.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 7831-7835
    • Swaneck, G.E.1    Fishman, J.2
  • 7
    • 0021709492 scopus 로고
    • Biochemical pharmacology of antiestrogen action
    • Jordan V.C. Biochemical pharmacology of antiestrogen action. Pharmacol. Rev. 36:1984;245-270.
    • (1984) Pharmacol. Rev. , vol.36 , pp. 245-270
    • Jordan, V.C.1
  • 8
    • 0027172047 scopus 로고
    • A current view of tamoxifen for the treatment and prevention of breast cancer
    • Jordan V.C. A current view of tamoxifen for the treatment and prevention of breast cancer. Br. J. Pharmacol. 110:1993;507-517.
    • (1993) Br. J. Pharmacol. , vol.110 , pp. 507-517
    • Jordan, V.C.1
  • 9
    • 0028018928 scopus 로고
    • Aromatase and its inhibitors in breast cancer treatment - overview and perspective
    • Brodie A.M., Santen R.J. Aromatase and its inhibitors in breast cancer treatment - overview and perspective. Breast Cancer Res. Treat. 30:1994;1-6.
    • (1994) Breast Cancer Res. Treat. , vol.30 , pp. 1-6
    • Brodie, A.M.1    Santen, R.J.2
  • 10
    • 0026702938 scopus 로고
    • Effects of synthetic Vitamin D analogues on breast cancer cell proliferation in vivo and in vitro
    • Colston K.W., Chander S.K., Mackay A.G., Coombes R.C. Effects of synthetic Vitamin D analogues on breast cancer cell proliferation in vivo and in vitro. Biochem. Pharmacol. 44:1992;693-702.
    • (1992) Biochem. Pharmacol. , vol.44 , pp. 693-702
    • Colston, K.W.1    Chander, S.K.2    MacKay, A.G.3    Coombes, R.C.4
  • 11
    • 0001319804 scopus 로고
    • Retinoids and human cancer
    • M.B. Sporn, A.B. Roberts, & D.S. Goodman. New York: Raven Press
    • Hong W.K., Itri L.M. Retinoids and human cancer. Sporn M.B., Roberts A.B., Goodman D.S. The Retinoids: Biology, Chemistry, and Medicine. 1994;597-630 Raven Press, New York.
    • (1994) The Retinoids: Biology, Chemistry, and Medicine , pp. 597-630
    • Hong, W.K.1    Itri, L.M.2
  • 12
    • 0021683985 scopus 로고
    • Growth inhibition by retinol of a human breast carcinoma cell line in vitro and in athymic mice
    • Fraker L.D., Halter S.A., Forbes J.T. Growth inhibition by retinol of a human breast carcinoma cell line in vitro and in athymic mice. Cancer Res. 44:1984;5757-5763.
    • (1984) Cancer Res. , vol.44 , pp. 5757-5763
    • Fraker, L.D.1    Halter, S.A.2    Forbes, J.T.3
  • 13
    • 0029118684 scopus 로고
    • Modulation of gene expression and endocrine response pathways by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds
    • Safe S. Modulation of gene expression and endocrine response pathways by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds. Pharmacol. Therap. 67:1995;247-281.
    • (1995) Pharmacol. Therap. , vol.67 , pp. 247-281
    • Safe, S.1
  • 14
    • 0000362058 scopus 로고    scopus 로고
    • Antiestrogenic activity of TCDD and related compounds
    • K.S. Korach. New York: Marcel Dekker
    • Zacharewski T., Safe S. Antiestrogenic activity of TCDD and related compounds. Korach K.S. Reproductive and Developmental Toxicology. 1998;431-448 Marcel Dekker, New York.
    • (1998) Reproductive and Developmental Toxicology , pp. 431-448
    • Zacharewski, T.1    Safe, S.2
  • 15
    • 0031747226 scopus 로고    scopus 로고
    • Interactions between hormone and chemicals in breast cancer
    • Safe S. Interactions between hormone and chemicals in breast cancer. Annu. Rev. Pharmacol. Toxicol. 38:1998;121-158.
    • (1998) Annu. Rev. Pharmacol. Toxicol. , vol.38 , pp. 121-158
    • Safe, S.1
  • 17
    • 0028285283 scopus 로고
    • Inhibition of 7,12-dimethylbenzanthracene-induced rat mammary tumor growth by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Holcomb M., Safe S. Inhibition of 7,12-dimethylbenzanthracene-induced rat mammary tumor growth by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Cancer Lett. 82:1994;43-47.
    • (1994) Cancer Lett. , vol.82 , pp. 43-47
    • Holcomb, M.1    Safe, S.2
  • 18
    • 0028810505 scopus 로고
    • Persistence of TCDD-induced hepatic cell proliferation and growth of enzyme altered foci after chronic exposure followed by cessation of treatment in DEN initiated female rats
    • Tritscher A.M., Clark G.C., Sewall C., Sills R.C., Maronpot R., Lucier G.W. Persistence of TCDD-induced hepatic cell proliferation and growth of enzyme altered foci after chronic exposure followed by cessation of treatment in DEN initiated female rats. Carcinogenesis. 16:1995;2807-2811.
    • (1995) Carcinogenesis , vol.16 , pp. 2807-2811
    • Tritscher, A.M.1    Clark, G.C.2    Sewall, C.3    Sills, R.C.4    Maronpot, R.5    Lucier, G.W.6
  • 19
    • 0027214018 scopus 로고
    • Correlation of in vitro and in vivo growth suppression of MCF-7 human breast cancer by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Gierthy J.F., Bennett J.A., Bradley L.M., Cutler D.S. Correlation of in vitro and in vivo growth suppression of MCF-7 human breast cancer by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Cancer Res. 53:1993;3149-3153.
    • (1993) Cancer Res. , vol.53 , pp. 3149-3153
    • Gierthy, J.F.1    Bennett, J.A.2    Bradley, L.M.3    Cutler, D.S.4
  • 20
    • 0030731436 scopus 로고    scopus 로고
    • Inhibition of 7,12-dimethylbenz[a]anthracene-induced rat mammary tumor growth by aryl hydrocarbon receptor agonists
    • McDougal A., Wilson C., Safe S. Inhibition of 7,12-dimethylbenz[a]anthracene-induced rat mammary tumor growth by aryl hydrocarbon receptor agonists. Cancer Lett. 120:1997;53-63.
    • (1997) Cancer Lett. , vol.120 , pp. 53-63
    • McDougal, A.1    Wilson, C.2    Safe, S.3
  • 21
    • 0031715037 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor-mediated antiestrogenic and antitumorigenic activity of diindolylmethane
    • Chen I., McDougal A., Wang F., Safe S. Aryl hydrocarbon receptor-mediated antiestrogenic and antitumorigenic activity of diindolylmethane. Carcinogenesis. 19:1998;1631-1639.
    • (1998) Carcinogenesis , vol.19 , pp. 1631-1639
    • Chen, I.1    McDougal, A.2    Wang, F.3    Safe, S.4
  • 22
    • 0032842573 scopus 로고    scopus 로고
    • Development of selective aryl hydrocarbon receptor modulators (SARMs) for treatment of breast cancer
    • Safe S., Qin C., McDougal A. Development of selective aryl hydrocarbon receptor modulators (SARMs) for treatment of breast cancer. Exp. Opin. Invest. Drugs. 8:1999;1385-1396.
    • (1999) Exp. Opin. Invest. Drugs , vol.8 , pp. 1385-1396
    • Safe, S.1    Qin, C.2    McDougal, A.3
  • 23
    • 2442464650 scopus 로고
    • Uterine peroxidase as a marker for estrogen action
    • Lyttle C.R., DeSombre E.R. Uterine peroxidase as a marker for estrogen action. Proc. Natl. Acad. Sci. USA. 74:1977;3162-3166.
    • (1977) Proc. Natl. Acad. Sci. USA , vol.74 , pp. 3162-3166
    • Lyttle, C.R.1    Desombre, E.R.2
  • 24
    • 0028180131 scopus 로고
    • Benzo[a]pyrene resistant (BaPR) human breast cancer cells: A unique aryl hydrocarbon (Ah)-non-responsive clone
    • Moore M., Wang X., Lu Y.-F., Wormke M., Craig A., Gerlach J., Burghardt R., Safe S. Benzo[a]pyrene resistant (BaPR) human breast cancer cells: a unique aryl hydrocarbon (Ah)-non-responsive clone. J. Biol. Chem. 269:1994;11751-11759.
    • (1994) J. Biol. Chem. , vol.269 , pp. 11751-11759
    • Moore, M.1    Wang, X.2    Lu, Y.-F.3    Wormke, M.4    Craig, A.5    Gerlach, J.6    Burghardt, R.7    Safe, S.8
  • 25
    • 0023816418 scopus 로고
    • Comparative antiestrogenic activities of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 6-methyl-1,3,8- trichlorodibenzofuran in the female rat
    • Astroff B., Safe S. Comparative antiestrogenic activities of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 6-methyl-1,3,8- trichlorodibenzofuran in the female rat. Toxicol. Appl. Pharmacol. 95:1988;435-443.
    • (1988) Toxicol. Appl. Pharmacol. , vol.95 , pp. 435-443
    • Astroff, B.1    Safe, S.2
  • 26
    • 0029598803 scopus 로고
    • Alkyl polychlorinated dibenzofurans and related compounds as antiestrogens in the female rat uterus: Structure-activity studies
    • Dickerson R., Howie-Keller L., Safe S. Alkyl polychlorinated dibenzofurans and related compounds as antiestrogens in the female rat uterus: structure-activity studies. Toxicol. Appl. Pharmacol. 135:1995;287-298.
    • (1995) Toxicol. Appl. Pharmacol. , vol.135 , pp. 287-298
    • Dickerson, R.1    Howie-Keller, L.2    Safe, S.3
  • 27
    • 0018137952 scopus 로고
    • Inhibition of aromatic hydrocarbon-induced neoplasia by naturally occurring indoles
    • Wattenberg L.W., Loub W.D. Inhibition of aromatic hydrocarbon-induced neoplasia by naturally occurring indoles. Cancer Res. 38:1978;1410-1413.
    • (1978) Cancer Res. , vol.38 , pp. 1410-1413
    • Wattenberg, L.W.1    Loub, W.D.2
  • 28
    • 0025140870 scopus 로고
    • Inhibitory effect of sinigrin and indole-3-carbinol in diethylnitrosamine-induced hepatocarcinogenesis in male ACI/N rats
    • Tanaka T., Mori Y., Morishita Y., Hara A., Ohno T., Kojima T., Mori H. Inhibitory effect of sinigrin and indole-3-carbinol in diethylnitrosamine-induced hepatocarcinogenesis in male ACI/N rats. Carcinogenesis. 11:1990;1403-1406.
    • (1990) Carcinogenesis , vol.11 , pp. 1403-1406
    • Tanaka, T.1    Mori, Y.2    Morishita, Y.3    Hara, A.4    Ohno, T.5    Kojima, T.6    Mori, H.7
  • 30
    • 0028298317 scopus 로고
    • Biphasic modifying effect on indole-3-carbinol on diethylnitrosamine-induced preneoplastic glutathione S-transferase placental form-positive liver cell foci in Sprague-Dawley rats
    • Kim D.J., Lee K.K., Han B.S., Ahn B., Bae J.H., Jang J.J. Biphasic modifying effect on indole-3-carbinol on diethylnitrosamine-induced preneoplastic glutathione S-transferase placental form-positive liver cell foci in Sprague-Dawley rats. Jpn. J. Cancer Res. 85:1994;578-583.
    • (1994) Jpn. J. Cancer Res. , vol.85 , pp. 578-583
    • Kim, D.J.1    Lee, K.K.2    Han, B.S.3    Ahn, B.4    Bae, J.H.5    Jang, J.J.6
  • 31
    • 0025317426 scopus 로고
    • Effects of indole-3-carbinol on lung tumorigenesis and DNA methylation induced by 4-(methylnitrosamino)-1-(3-pyridl)-1-butanone (NNK) and on the metabolism and disposition of NNK in A/J mice
    • Morse M.A., LaGreca S.D., Amin S.G., Chung F.L. Effects of indole-3-carbinol on lung tumorigenesis and DNA methylation induced by 4-(methylnitrosamino)-1-(3-pyridl)-1-butanone (NNK) and on the metabolism and disposition of NNK in A/J mice. Cancer Res. 50:1990;1613-1617.
    • (1990) Cancer Res. , vol.50 , pp. 1613-1617
    • Morse, M.A.1    Lagreca, S.D.2    Amin, S.G.3    Chung, F.L.4
  • 32
    • 0028281779 scopus 로고
    • Chemoprevention of spontaneous endometrial cancer in female Donryu rats by dietary indol-3-carbinol
    • Kojima T., Tanaka T., Mori H. Chemoprevention of spontaneous endometrial cancer in female Donryu rats by dietary indol-3-carbinol. Cancer Res. 54:1994;1446-1449.
    • (1994) Cancer Res. , vol.54 , pp. 1446-1449
    • Kojima, T.1    Tanaka, T.2    Mori, H.3
  • 34
    • 0026046412 scopus 로고
    • Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo - comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Bjeldanes L.F., Kim J.Y., Grose K.R., Bartholomew J.C., Bradfield C.A. Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo - comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin. Proc. Natl. Acad. Sci. USA. 88:1991;9543-9547.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 9543-9547
    • Bjeldanes, L.F.1    Kim, J.Y.2    Grose, K.R.3    Bartholomew, J.C.4    Bradfield, C.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.