Inactivation of COX-2, HMLH1 and CDKN2A gene by promoter methylation in gastric cancer: Relationship with histological subtype, tumor location and helicobacter pylori genotype

Pathobiology

Volumn 78, Issue 5, 2011, Pages 266-276

  Alves, Markênia Kélia Santos ^a   Ferrasi, Adriana Camargo ^b   Lima, Valeska Portela ^a   Ferreira, Márcia Valéria Pitombeira ^a   De Moura Campos Pardini, Maria Inês ^b   Rabenhorst, Silvia Helena Barem ^a  

^a FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

COX 2; Gastric cancer; Helicobacter pylori genotypes; Histological subtypes; HMLH1; Methylation; p16 INK4A; Tumor location

Indexed keywords

BIOLOGICAL MARKER; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLOOXYGENASE 2; PROTEIN MLH1;

ARTICLE; CARDIA; CONTROLLED STUDY; CORRELATION COEFFICIENT; DNA EXTRACTION; DNA METHYLATION; GENE EXPRESSION PROFILING; GENE INACTIVATION; GENOTYPE; HELICOBACTER PYLORI; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; STOMACH CANCER;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOCARCINOMA; AGED; CYCLOOXYGENASE 2; DNA METHYLATION; FEMALE; GENES, P16; GENOTYPE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NEOPLASM STAGING; NUCLEAR PROTEINS; POLYMERASE CHAIN REACTION; PROMOTER REGIONS, GENETIC; STOMACH NEOPLASMS;

HELICOBACTER PYLORI;

EID: 80051610922     PISSN: 10152008     EISSN: 14230291     Source Type: Journal    
DOI: 10.1159/000329475     Document Type: Article

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