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Volumn 15, Issue 5, 2011, Pages 383-389

Pharmacological modulation of late radio-induced side effects;Modulation pharmacologique des effets tardifs de l'irradiation

Author keywords

Late effect; Pharmacomodulation; Radiotherapy; Sequelae

Indexed keywords

FIBROSIS; HUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; QUALITY OF LIFE; RADIATION SICKNESS; RADIOTHERAPY; SHORT SURVEY; TOXICITY;

EID: 79961211357     PISSN: 12783218     EISSN: 17696658     Source Type: Journal    
DOI: 10.1016/j.canrad.2011.01.008     Document Type: Short Survey
Times cited : (7)

References (99)
  • 1
    • 0031773119 scopus 로고    scopus 로고
    • How do tissues respond to damage at the cellular level? The role of cytokines in irradiated tissues
    • Barcellos-Hoff M.H. How do tissues respond to damage at the cellular level? The role of cytokines in irradiated tissues. Radiat Res 1998, 150:S109-S120.
    • (1998) Radiat Res , vol.150
    • Barcellos-Hoff, M.H.1
  • 2
    • 33947536682 scopus 로고    scopus 로고
    • Responses of normal cells to ionizing radiation
    • Rodemann H.P., Blaese M.A. Responses of normal cells to ionizing radiation. Semin Radiat Oncol 2007, 17:81-88.
    • (2007) Semin Radiat Oncol , vol.17 , pp. 81-88
    • Rodemann, H.P.1    Blaese, M.A.2
  • 3
    • 0036283219 scopus 로고    scopus 로고
    • The radiotherapeutic injury: a complex 'wound'
    • Denham J.W., Hauer-Jensen M. The radiotherapeutic injury: a complex 'wound'. Radiother Oncol 2002, 63:129-145.
    • (2002) Radiother Oncol , vol.63 , pp. 129-145
    • Denham, J.W.1    Hauer-Jensen, M.2
  • 4
    • 0034333042 scopus 로고    scopus 로고
    • Acute radiation proctitis: a sequential clinicopathologic study during pelvic radiotherapy
    • Hovdenak N., Fajardo L.F., Hauer-Jensen M. Acute radiation proctitis: a sequential clinicopathologic study during pelvic radiotherapy. Int J Radiat Oncol Biol Phys 2000, 48:1111-1117.
    • (2000) Int J Radiat Oncol Biol Phys , vol.48 , pp. 1111-1117
    • Hovdenak, N.1    Fajardo, L.F.2    Hauer-Jensen, M.3
  • 5
    • 0001515617 scopus 로고
    • Erfahrungen über die verträglichkeitsgrenze für röntgenstrahlen und deren nutzanwendung zur verhütung von schäden
    • Holthusen H. Erfahrungen über die verträglichkeitsgrenze für röntgenstrahlen und deren nutzanwendung zur verhütung von schäden. Strahlentherapie 1936, 57:254-269.
    • (1936) Strahlentherapie , vol.57 , pp. 254-269
    • Holthusen, H.1
  • 6
    • 77955328522 scopus 로고    scopus 로고
    • Effets secondaires des rayonnements sur les tissus sains et organes à risque
    • Cosset J.M. Effets secondaires des rayonnements sur les tissus sains et organes à risque. Cancer Radiother 2010, 14:228-231.
    • (2010) Cancer Radiother , vol.14 , pp. 228-231
    • Cosset, J.M.1
  • 9
    • 0035194395 scopus 로고    scopus 로고
    • Consequential late effects in normal tissues
    • Dorr W., Hendry J.H. Consequential late effects in normal tissues. Radiother Oncol 2001, 61:223-231.
    • (2001) Radiother Oncol , vol.61 , pp. 223-231
    • Dorr, W.1    Hendry, J.H.2
  • 10
    • 0028351348 scopus 로고
    • Patient-to-patient variability in the expression of radiation-induced normal tissue injury
    • Bentzen S.M., Overgaard J. Patient-to-patient variability in the expression of radiation-induced normal tissue injury. Semin Radiat Oncol 1994, 4:68-80.
    • (1994) Semin Radiat Oncol , vol.4 , pp. 68-80
    • Bentzen, S.M.1    Overgaard, J.2
  • 11
    • 0030232710 scopus 로고    scopus 로고
    • The p53 gene as a modifier of intrinsic radiosensitivity: implications for radiotherapy
    • Bristow R.G., Benchimol S., Hill R.P. The p53 gene as a modifier of intrinsic radiosensitivity: implications for radiotherapy. Radiother Oncol 1996, 40:197-223.
    • (1996) Radiother Oncol , vol.40 , pp. 197-223
    • Bristow, R.G.1    Benchimol, S.2    Hill, R.P.3
  • 13
    • 0035184902 scopus 로고    scopus 로고
    • The inherited basis of human radiosensitivity
    • Gatti R.A. The inherited basis of human radiosensitivity. Acta Oncol 2001, 40:702-711.
    • (2001) Acta Oncol , vol.40 , pp. 702-711
    • Gatti, R.A.1
  • 14
    • 0037365789 scopus 로고    scopus 로고
    • ATM and related protein kinases: safeguarding genome integrity
    • Shiloh Y. ATM and related protein kinases: safeguarding genome integrity. Nat Rev Cancer 2003, 3:155-168.
    • (2003) Nat Rev Cancer , vol.3 , pp. 155-168
    • Shiloh, Y.1
  • 15
    • 0043066892 scopus 로고    scopus 로고
    • Relative roles of ICAM-1 and VCAM-1 in the pathogenesis of experimental radiation-induced intestinal inflammation
    • Molla M., Gironella M., Miquel R., Tovar V., Engel P., Biete A., et al. Relative roles of ICAM-1 and VCAM-1 in the pathogenesis of experimental radiation-induced intestinal inflammation. Int J Radiat Oncol Biol Phys 2003, 57:264-273.
    • (2003) Int J Radiat Oncol Biol Phys , vol.57 , pp. 264-273
    • Molla, M.1    Gironella, M.2    Miquel, R.3    Tovar, V.4    Engel, P.5    Biete, A.6
  • 16
    • 34447290442 scopus 로고    scopus 로고
    • Radiation-induced intestinal inflammation
    • Molla M., Panes J. Radiation-induced intestinal inflammation. World J Gastroenterol 2007, 13:3043-3046.
    • (2007) World J Gastroenterol , vol.13 , pp. 3043-3046
    • Molla, M.1    Panes, J.2
  • 17
    • 0032696277 scopus 로고    scopus 로고
    • Influence of dose-rate on inflammatory damage and adhesion molecule expression after abdominal radiation in the rat
    • Molla M., Panes J., Casadevall M., Salas A., Conill C., Biete A., et al. Influence of dose-rate on inflammatory damage and adhesion molecule expression after abdominal radiation in the rat. Int J Radiat Oncol Biol Phys 1999, 45:1011-1018.
    • (1999) Int J Radiat Oncol Biol Phys , vol.45 , pp. 1011-1018
    • Molla, M.1    Panes, J.2    Casadevall, M.3    Salas, A.4    Conill, C.5    Biete, A.6
  • 18
    • 3543107212 scopus 로고    scopus 로고
    • Fibrotic disease and the T(H)1/T(H)2 paradigm
    • Wynn T.A. Fibrotic disease and the T(H)1/T(H)2 paradigm. Nat Rev Immunol 2004, 4:583-594.
    • (2004) Nat Rev Immunol , vol.4 , pp. 583-594
    • Wynn, T.A.1
  • 20
    • 0015225464 scopus 로고
    • Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction
    • Gabbiani G., Ryan G.B., Majne G. Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction. Experientia 1971, 27:549-550.
    • (1971) Experientia , vol.27 , pp. 549-550
    • Gabbiani, G.1    Ryan, G.B.2    Majne, G.3
  • 22
    • 38549159026 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of fibrosis
    • Wynn T.A. Cellular and molecular mechanisms of fibrosis. J Pathol 2008, 214:199-210.
    • (2008) J Pathol , vol.214 , pp. 199-210
    • Wynn, T.A.1
  • 23
    • 0035020567 scopus 로고    scopus 로고
    • Fibrosis of the lung and other tissues: new concepts in pathogenesis and treatment
    • Sime P.J., O'Reilly K.M. Fibrosis of the lung and other tissues: new concepts in pathogenesis and treatment. Clin Immunol 2001, 99:308-319.
    • (2001) Clin Immunol , vol.99 , pp. 308-319
    • Sime, P.J.1    O'Reilly, K.M.2
  • 24
    • 33744944779 scopus 로고    scopus 로고
    • Epithelial origin of myofibroblasts during fibrosis in the lung
    • Willis B.C., duBois R.M., Borok Z. Epithelial origin of myofibroblasts during fibrosis in the lung. Proc Am Thorac Soc 2006, 3:377-382.
    • (2006) Proc Am Thorac Soc , vol.3 , pp. 377-382
    • Willis, B.C.1    duBois, R.M.2    Borok, Z.3
  • 25
    • 0036885067 scopus 로고    scopus 로고
    • The lineage decisions of helper T cells
    • Murphy K.M., Reiner S.L. The lineage decisions of helper T cells. Nat Rev Immunol 2002, 2:933-944.
    • (2002) Nat Rev Immunol , vol.2 , pp. 933-944
    • Murphy, K.M.1    Reiner, S.L.2
  • 26
    • 1642423304 scopus 로고    scopus 로고
    • The endothelial cell is a unique target of radiation: an overview
    • CRC Press, Boca Raton, FL, D.B. Rubin (Ed.)
    • Fajardo L.F. The endothelial cell is a unique target of radiation: an overview. The radiation biology of the vascular endothelium 1998, 1-13. CRC Press, Boca Raton, FL. D.B. Rubin (Ed.).
    • (1998) The radiation biology of the vascular endothelium , pp. 1-13
    • Fajardo, L.F.1
  • 27
    • 0002747182 scopus 로고
    • Radiation-induced vascular injury and its relation to late effects in normal tissues
    • Law M.P. Radiation-induced vascular injury and its relation to late effects in normal tissues. Adv Radiat Biol 1981, 9.
    • (1981) Adv Radiat Biol , pp. 9
    • Law, M.P.1
  • 28
    • 0029561153 scopus 로고
    • E-selectin gene induction by ionizing radiation is independent of cytokine induction
    • Hallahan D., Clark E.T., Kuchibhotla J., et al. E-selectin gene induction by ionizing radiation is independent of cytokine induction. Biochem Biophys Res Commun 1995, 217:784-795.
    • (1995) Biochem Biophys Res Commun , vol.217 , pp. 784-795
    • Hallahan, D.1    Clark, E.T.2    Kuchibhotla, J.3
  • 29
    • 0029841449 scopus 로고    scopus 로고
    • Ionizing irradiation increases transcription of the von Willebrand factor gene in endothelial cells
    • Jahroudi N., Ardekani A.M., Greenberger J.S. Ionizing irradiation increases transcription of the von Willebrand factor gene in endothelial cells. Blood 1996, 88:3801-3814.
    • (1996) Blood , vol.88 , pp. 3801-3814
    • Jahroudi, N.1    Ardekani, A.M.2    Greenberger, J.S.3
  • 30
    • 0021792045 scopus 로고
    • Prostacyclin synthesis in irradiated endothelial cells cultured from bovine aorta
    • Rubin D.B., Drab E.A., Ts'ao C.H., Gardner D., Ward W.F. Prostacyclin synthesis in irradiated endothelial cells cultured from bovine aorta. J Appl Physiol 1985, 58:592-597.
    • (1985) J Appl Physiol , vol.58 , pp. 592-597
    • Rubin, D.B.1    Drab, E.A.2    Ts'ao, C.H.3    Gardner, D.4    Ward, W.F.5
  • 31
    • 0029042423 scopus 로고
    • The effect of ionizing radiation on endothelial tissue factor activity and its cellular localization
    • Verheij M., Dewit L.G., van Mourik J.A. The effect of ionizing radiation on endothelial tissue factor activity and its cellular localization. Thromb Haemost 1995, 73:894-895.
    • (1995) Thromb Haemost , vol.73 , pp. 894-895
    • Verheij, M.1    Dewit, L.G.2    van Mourik, J.A.3
  • 32
    • 0023786380 scopus 로고
    • Radiation-induced pulmonary endothelial dysfunction in rats: modification by an inhibitor of angiotensin converting enzyme
    • Ward W.F., Kim Y.T., Molteni A., Solliday N.H. Radiation-induced pulmonary endothelial dysfunction in rats: modification by an inhibitor of angiotensin converting enzyme. Int J Radiat Oncol Biol Phys 1988, 15:135-140.
    • (1988) Int J Radiat Oncol Biol Phys , vol.15 , pp. 135-140
    • Ward, W.F.1    Kim, Y.T.2    Molteni, A.3    Solliday, N.H.4
  • 33
    • 0026739571 scopus 로고
    • Thrombomodulin as a marker of radiation-induced endothelial cell injury
    • Zhou Q., Zhao Y., Li P., Bai X., Ruan C. Thrombomodulin as a marker of radiation-induced endothelial cell injury. Radiat Res 1992, 131:285-289.
    • (1992) Radiat Res , vol.131 , pp. 285-289
    • Zhou, Q.1    Zhao, Y.2    Li, P.3    Bai, X.4    Ruan, C.5
  • 34
    • 33947386671 scopus 로고    scopus 로고
    • The late radiotherapy normal tissue injury phenotypes of telangiectasia, fibrosis and atrophy in breast cancer patients have distinct genotype-dependent causes
    • Giotopoulos G., Symonds R.P., Foweraker K., Griffin M., Peat I., Osman A., et al. The late radiotherapy normal tissue injury phenotypes of telangiectasia, fibrosis and atrophy in breast cancer patients have distinct genotype-dependent causes. Br J Cancer 2007, 96:1001-1007.
    • (2007) Br J Cancer , vol.96 , pp. 1001-1007
    • Giotopoulos, G.1    Symonds, R.P.2    Foweraker, K.3    Griffin, M.4    Peat, I.5    Osman, A.6
  • 35
    • 0026403632 scopus 로고
    • Terminal differentiation of human fibroblasts is induced by radiation
    • [discussion 1142, 1133]
    • Rodemann H.P., Peterson H.P., Schwenke K., von Wangenheim K.H. Terminal differentiation of human fibroblasts is induced by radiation. Scanning Microsc 1991, 5:1135-1142. [discussion 1142, 1133].
    • (1991) Scanning Microsc , vol.5 , pp. 1135-1142
    • Rodemann, H.P.1    Peterson, H.P.2    Schwenke, K.3    von Wangenheim, K.H.4
  • 36
    • 0028829998 scopus 로고
    • Radiation-induced alterations of the proliferation dynamics of human skin fibroblasts after repeated irradiation in the subtherapeutic dose range
    • Bumann J., Santo-Holtje L., Loffler H., Bamberg M., Rodemann H.P. Radiation-induced alterations of the proliferation dynamics of human skin fibroblasts after repeated irradiation in the subtherapeutic dose range. Strahlenther Onkol 1995, 171:35-41.
    • (1995) Strahlenther Onkol , vol.171 , pp. 35-41
    • Bumann, J.1    Santo-Holtje, L.2    Loffler, H.3    Bamberg, M.4    Rodemann, H.P.5
  • 37
    • 0029736871 scopus 로고    scopus 로고
    • Redox-mediated activation of latent transforming growth factor-beta 1
    • Barcellos-Hoff M.H., Dix T.A. Redox-mediated activation of latent transforming growth factor-beta 1. Mol Endocrinol 1996, 10:1077-1083.
    • (1996) Mol Endocrinol , vol.10 , pp. 1077-1083
    • Barcellos-Hoff, M.H.1    Dix, T.A.2
  • 38
    • 33845358508 scopus 로고    scopus 로고
    • Isoform-specific activation of latent transforming growth factor beta (LTGF-beta) by reactive oxygen species
    • Jobling M.F., Mott J.D., Finnegan M.T., Jurukovski V., Erickson A.C., Walian P.J., et al. Isoform-specific activation of latent transforming growth factor beta (LTGF-beta) by reactive oxygen species. Radiat Res 2006, 166:839-848.
    • (2006) Radiat Res , vol.166 , pp. 839-848
    • Jobling, M.F.1    Mott, J.D.2    Finnegan, M.T.3    Jurukovski, V.4    Erickson, A.C.5    Walian, P.J.6
  • 39
    • 0034320191 scopus 로고    scopus 로고
    • Recombinant soluble transforming growth factor beta type II receptor ameliorates radiation enteropathy in mice
    • Zheng H., Wang J., Koteliansky V.E., Gotwals P.J., Hauer-Jensen M. Recombinant soluble transforming growth factor beta type II receptor ameliorates radiation enteropathy in mice. Gastroenterology 2000, 119:1286-1296.
    • (2000) Gastroenterology , vol.119 , pp. 1286-1296
    • Zheng, H.1    Wang, J.2    Koteliansky, V.E.3    Gotwals, P.J.4    Hauer-Jensen, M.5
  • 40
    • 44449179168 scopus 로고    scopus 로고
    • Small molecular inhibitor of transforming growth factor-beta protects against development of radiation-induced lung injury
    • Anscher M.S., Thrasher B., Zgonjanin L., Rabbani Z.N., Corbley M.J., Fu K., et al. Small molecular inhibitor of transforming growth factor-beta protects against development of radiation-induced lung injury. Int J Radiat Oncol Biol Phys 2008, 71:829-837.
    • (2008) Int J Radiat Oncol Biol Phys , vol.71 , pp. 829-837
    • Anscher, M.S.1    Thrasher, B.2    Zgonjanin, L.3    Rabbani, Z.N.4    Corbley, M.J.5    Fu, K.6
  • 41
    • 2442659450 scopus 로고    scopus 로고
    • Gene expression profile in human late radiation enteritis obtained by high-density cDNA array hybridization
    • Vozenin-Brotons M.C., Milliat F., Linard C., Strup C., François A., Sabourin J.C., et al. Gene expression profile in human late radiation enteritis obtained by high-density cDNA array hybridization. Radiat Res 2004, 161:299-311.
    • (2004) Radiat Res , vol.161 , pp. 299-311
    • Vozenin-Brotons, M.C.1    Milliat, F.2    Linard, C.3    Strup, C.4    François, A.5    Sabourin, J.C.6
  • 42
    • 0035151723 scopus 로고    scopus 로고
    • Contribution of small GTPase Rho and its target protein rock in a murine model of lung fibrosis
    • Shimizu Y., Dobashi K., Iizuka K., Horie T., Suzuki K., Tukagoshi H., et al. Contribution of small GTPase Rho and its target protein rock in a murine model of lung fibrosis. Am J Respir Crit Care Med 2001, 163:210-217.
    • (2001) Am J Respir Crit Care Med , vol.163 , pp. 210-217
    • Shimizu, Y.1    Dobashi, K.2    Iizuka, K.3    Horie, T.4    Suzuki, K.5    Tukagoshi, H.6
  • 43
    • 0034870254 scopus 로고    scopus 로고
    • Expression of connective tissue growth factor in human renal fibroblasts: regulatory roles of RhoA and cAMP
    • Heusinger-Ribeiro J., Eberlein M., Wahab N.A., Goppelt-Struebe M. Expression of connective tissue growth factor in human renal fibroblasts: regulatory roles of RhoA and cAMP. J Am Soc Nephrol 2001, 12:1853-1861.
    • (2001) J Am Soc Nephrol , vol.12 , pp. 1853-1861
    • Heusinger-Ribeiro, J.1    Eberlein, M.2    Wahab, N.A.3    Goppelt-Struebe, M.4
  • 44
    • 0036236193 scopus 로고    scopus 로고
    • Y-27632 prevents tubulointerstitial fibrosis in mouse kidneys with unilateral ureteral obstruction
    • Nagatoya K., Moriyama T., Kawada N., Takeji M., Oseto S., Murozono T., et al. Y-27632 prevents tubulointerstitial fibrosis in mouse kidneys with unilateral ureteral obstruction. Kidney Int 2002, 61:1684-1695.
    • (2002) Kidney Int , vol.61 , pp. 1684-1695
    • Nagatoya, K.1    Moriyama, T.2    Kawada, N.3    Takeji, M.4    Oseto, S.5    Murozono, T.6
  • 45
    • 0034888856 scopus 로고    scopus 로고
    • Rho-dependent inhibition of the induction of connective tissue growth factor (CTGF) by HMG CoA reductase inhibitors (statins)
    • Eberlein M., Heusinger-Ribeiro J., Goppelt-Struebe M. Rho-dependent inhibition of the induction of connective tissue growth factor (CTGF) by HMG CoA reductase inhibitors (statins). Br J Pharmacol 2001, 133:1172-1180.
    • (2001) Br J Pharmacol , vol.133 , pp. 1172-1180
    • Eberlein, M.1    Heusinger-Ribeiro, J.2    Goppelt-Struebe, M.3
  • 46
    • 0034793893 scopus 로고    scopus 로고
    • Inhibitory effect of Y-27632, a ROCK inhibitor, on progression of rat liver fibrosis in association with inactivation of hepatic stellate cells
    • Murata T., Arii S., Nakamura T., Mori A., Kaido T., Furuyama H., et al. Inhibitory effect of Y-27632, a ROCK inhibitor, on progression of rat liver fibrosis in association with inactivation of hepatic stellate cells. J Hepatol 2001, 35:474-481.
    • (2001) J Hepatol , vol.35 , pp. 474-481
    • Murata, T.1    Arii, S.2    Nakamura, T.3    Mori, A.4    Kaido, T.5    Furuyama, H.6
  • 47
    • 14544278377 scopus 로고    scopus 로고
    • Inhibition of Rho kinase modulates radiation induced fibrogenic phenotype in intestinal smooth muscle cells through alteration of the cytoskeleton and connective tissue growth factor expression
    • Bourgier C., Haydont V., Milliat F., François A., Holler V., Lasser P., et al. Inhibition of Rho kinase modulates radiation induced fibrogenic phenotype in intestinal smooth muscle cells through alteration of the cytoskeleton and connective tissue growth factor expression. Gut 2005, 54:336-343.
    • (2005) Gut , vol.54 , pp. 336-343
    • Bourgier, C.1    Haydont, V.2    Milliat, F.3    François, A.4    Holler, V.5    Lasser, P.6
  • 48
    • 34848906040 scopus 로고    scopus 로고
    • Pravastatin Inhibits the Rho/CCN2/extracellular matrix cascade in human fibrosis explants and improves radiation-induced intestinal fibrosis in rats
    • Haydont V., Bourgier C., Pocard M., Lusinchi A., Aigueperse J., Mathé D., et al. Pravastatin Inhibits the Rho/CCN2/extracellular matrix cascade in human fibrosis explants and improves radiation-induced intestinal fibrosis in rats. Clin Cancer Res 2007, 13:5331-5340.
    • (2007) Clin Cancer Res , vol.13 , pp. 5331-5340
    • Haydont, V.1    Bourgier, C.2    Pocard, M.3    Lusinchi, A.4    Aigueperse, J.5    Mathé, D.6
  • 49
    • 34948907775 scopus 로고    scopus 로고
    • Rho/ROCK pathway as a molecular target for modulation of intestinal radiation-induced toxicity
    • Haydont V., Bourgier C., Vozenin-Brotons M.C. Rho/ROCK pathway as a molecular target for modulation of intestinal radiation-induced toxicity. Br J Radiol 2007, 80:S32-S40.
    • (2007) Br J Radiol , vol.80
    • Haydont, V.1    Bourgier, C.2    Vozenin-Brotons, M.C.3
  • 50
    • 34547429999 scopus 로고    scopus 로고
    • Successful mitigation of delayed intestinal radiation injury using pravastatin is not associated with acute injury improvement or tumor protection
    • Haydont V., Gilliot O., Rivera S., Bourgier C., François A., Aigueperse J., et al. Successful mitigation of delayed intestinal radiation injury using pravastatin is not associated with acute injury improvement or tumor protection. Int J Radiat Oncol Biol Phys 2007, 68:1471-1482.
    • (2007) Int J Radiat Oncol Biol Phys , vol.68 , pp. 1471-1482
    • Haydont, V.1    Gilliot, O.2    Rivera, S.3    Bourgier, C.4    François, A.5    Aigueperse, J.6
  • 51
    • 28444492266 scopus 로고    scopus 로고
    • Induction of CTGF by TGF-beta1 in normal and radiation enteritis human smooth muscle cells: Smad/Rho balance and therapeutic perspectives
    • Haydont V., Mathe D., Bourgier C., Abdelali J., Aigueperse J., Bourhis J., et al. Induction of CTGF by TGF-beta1 in normal and radiation enteritis human smooth muscle cells: Smad/Rho balance and therapeutic perspectives. Radiother Oncol 2005, 76:219-225.
    • (2005) Radiother Oncol , vol.76 , pp. 219-225
    • Haydont, V.1    Mathe, D.2    Bourgier, C.3    Abdelali, J.4    Aigueperse, J.5    Bourhis, J.6
  • 53
    • 0031093273 scopus 로고    scopus 로고
    • Alveolar macrophages stimulated with titanium dioxide, chrysotile asbestos, and residual oil fly ash upregulate the PDGF receptor-alpha on lung fibroblasts through an IL-1beta-dependent mechanism
    • Lindroos P.M., Coin P.G., Badgett A., Morgan D.L., Bonner J.C. Alveolar macrophages stimulated with titanium dioxide, chrysotile asbestos, and residual oil fly ash upregulate the PDGF receptor-alpha on lung fibroblasts through an IL-1beta-dependent mechanism. Am J Respir Cell Mol Biol 1997, 16:283-292.
    • (1997) Am J Respir Cell Mol Biol , vol.16 , pp. 283-292
    • Lindroos, P.M.1    Coin, P.G.2    Badgett, A.3    Morgan, D.L.4    Bonner, J.C.5
  • 54
    • 0030854832 scopus 로고    scopus 로고
    • Platelet-derived growth factor ligand and receptor expression in response to altered blood flow in vivo
    • Mondy J.S., Lindner V., Miyashiro J.K., Berk B.C., Dean R.H., Geary R.L. Platelet-derived growth factor ligand and receptor expression in response to altered blood flow in vivo. Circ Res 1997, 81:320-327.
    • (1997) Circ Res , vol.81 , pp. 320-327
    • Mondy, J.S.1    Lindner, V.2    Miyashiro, J.K.3    Berk, B.C.4    Dean, R.H.5    Geary, R.L.6
  • 55
    • 0032903716 scopus 로고    scopus 로고
    • Growth factors secreted by bronchial epithelial cells control myofibroblast proliferation: an in vitro co-culture model of airway remodeling in asthma
    • Zhang S., Smartt H., Holgate S.T., Roche W.R. Growth factors secreted by bronchial epithelial cells control myofibroblast proliferation: an in vitro co-culture model of airway remodeling in asthma. Lab Invest 1999, 79:395-405.
    • (1999) Lab Invest , vol.79 , pp. 395-405
    • Zhang, S.1    Smartt, H.2    Holgate, S.T.3    Roche, W.R.4
  • 56
    • 0035003785 scopus 로고    scopus 로고
    • PDGF-D is a specific, protease-activated ligand for the PDGF beta-receptor
    • Bergsten E., Uutela M., Li X., Ostman A., Heldin C.H., Alitalo K., et al. PDGF-D is a specific, protease-activated ligand for the PDGF beta-receptor. Nat Cell Biol 2001, 3:512-516.
    • (2001) Nat Cell Biol , vol.3 , pp. 512-516
    • Bergsten, E.1    Uutela, M.2    Li, X.3    Ostman, A.4    Heldin, C.H.5    Alitalo, K.6
  • 58
    • 0346096889 scopus 로고    scopus 로고
    • Modulation of PDGF-C and PDGF-D expression during bleomycin-induced lung fibrosis
    • Zhuo Y., Zhang J., Laboy M., Lasky J.A. Modulation of PDGF-C and PDGF-D expression during bleomycin-induced lung fibrosis. Am J Physiol Lung Cell Mol Physiol 2004, 286:L182-L188.
    • (2004) Am J Physiol Lung Cell Mol Physiol , vol.286
    • Zhuo, Y.1    Zhang, J.2    Laboy, M.3    Lasky, J.A.4
  • 59
    • 0028066982 scopus 로고
    • Expression of fibrogenic cytokines in rat small intestine after fractionated irradiation
    • Langberg C.W., Hauer-Jensen M., Sung C.C., Kane C.J. Expression of fibrogenic cytokines in rat small intestine after fractionated irradiation. Radiother Oncol 1994, 32:29-36.
    • (1994) Radiother Oncol , vol.32 , pp. 29-36
    • Langberg, C.W.1    Hauer-Jensen, M.2    Sung, C.C.3    Kane, C.J.4
  • 60
    • 0023853499 scopus 로고
    • Expression of platelet-derived growth factor receptors is induced on connective tissue cells during chronic synovial inflammation
    • Rubin K., Terracio L., Ronnstrand L., Heldin C.H., Klareskog L. Expression of platelet-derived growth factor receptors is induced on connective tissue cells during chronic synovial inflammation. Scand J Immunol 1988, 27:285-294.
    • (1988) Scand J Immunol , vol.27 , pp. 285-294
    • Rubin, K.1    Terracio, L.2    Ronnstrand, L.3    Heldin, C.H.4    Klareskog, L.5
  • 61
    • 0037981357 scopus 로고    scopus 로고
    • Increased binding and chemotactic capacities of PDGF-BB on fibroblasts in radiation pneumonitis
    • Tada H., Ogushi F., Tani K., Nishioka Y., Miyata J.Y., Sato K., et al. Increased binding and chemotactic capacities of PDGF-BB on fibroblasts in radiation pneumonitis. Radiat Res 2003, 159:805-811.
    • (2003) Radiat Res , vol.159 , pp. 805-811
    • Tada, H.1    Ogushi, F.2    Tani, K.3    Nishioka, Y.4    Miyata, J.Y.5    Sato, K.6
  • 62
    • 2942682928 scopus 로고    scopus 로고
    • Regulation of PDGF and its receptors in fibrotic diseases
    • Bonner J.C. Regulation of PDGF and its receptors in fibrotic diseases. Cytokine Growth Factor Rev 2004, 15:255-273.
    • (2004) Cytokine Growth Factor Rev , vol.15 , pp. 255-273
    • Bonner, J.C.1
  • 63
    • 33744783176 scopus 로고    scopus 로고
    • EGF and PDGF receptor tyrosine kinases as therapeutic targets for chronic lung diseases
    • Ingram J.L., Bonner J.C. EGF and PDGF receptor tyrosine kinases as therapeutic targets for chronic lung diseases. Curr Mol Med 2006, 6:409-421.
    • (2006) Curr Mol Med , vol.6 , pp. 409-421
    • Ingram, J.L.1    Bonner, J.C.2
  • 64
    • 20244364391 scopus 로고    scopus 로고
    • Inhibition of platelet-derived growth factor signaling attenuates pulmonary fibrosis
    • Abdollahi A., Li M., Ping G., Plathow C., Domhan S., Kiessling F., et al. Inhibition of platelet-derived growth factor signaling attenuates pulmonary fibrosis. J Exp Med 2005, 201:925-935.
    • (2005) J Exp Med , vol.201 , pp. 925-935
    • Abdollahi, A.1    Li, M.2    Ping, G.3    Plathow, C.4    Domhan, S.5    Kiessling, F.6
  • 65
    • 44149090296 scopus 로고    scopus 로고
    • Role of platelet-derived growth factors in physiology and medicine
    • Andrae J., Gallini R., Betsholtz C. Role of platelet-derived growth factors in physiology and medicine. Genes Dev 2008, 22:1276-1312.
    • (2008) Genes Dev , vol.22 , pp. 1276-1312
    • Andrae, J.1    Gallini, R.2    Betsholtz, C.3
  • 66
    • 33746840153 scopus 로고    scopus 로고
    • IGF-I mediated survival pathways in normal and malignant cells
    • Kurmasheva R.T., Houghton P.J. IGF-I mediated survival pathways in normal and malignant cells. Biochim Biophys Acta 2006, 1766:1-22.
    • (2006) Biochim Biophys Acta , vol.1766 , pp. 1-22
    • Kurmasheva, R.T.1    Houghton, P.J.2
  • 67
    • 0038398622 scopus 로고    scopus 로고
    • The insulin-like growth factor system and cancer
    • LeRoith D., Roberts C.T. The insulin-like growth factor system and cancer. Cancer Lett 2003, 195:127-137.
    • (2003) Cancer Lett , vol.195 , pp. 127-137
    • LeRoith, D.1    Roberts, C.T.2
  • 69
    • 77954909691 scopus 로고    scopus 로고
    • Silibinin attenuates cardiac hypertrophy and fibrosis through blocking EGFR-dependent signaling. J Cell Biochem
    • Ai W, Zhang Y, Tang QZ, Bian ZY, Liu C, Huang H, et al. Silibinin attenuates cardiac hypertrophy and fibrosis through blocking EGFR-dependent signaling. J Cell Biochem 2010;110:1111-22.
    • (2010) , vol.110 , pp. 1111-22
    • Ai, W.1    Zhang, Y.2    Tang, Q.Z.3    Bian, Z.Y.4    Liu, C.5    Huang, H.6
  • 70
    • 0022946275 scopus 로고
    • Treatment of radiofibrosis with liposomal superoxide dismutase. Preliminary results of 50 cases
    • Baillet F., Housset M., Michelson A.M., Puget K. Treatment of radiofibrosis with liposomal superoxide dismutase. Preliminary results of 50 cases. Free Radic Res Commun 1986, 1:387-394.
    • (1986) Free Radic Res Commun , vol.1 , pp. 387-394
    • Baillet, F.1    Housset, M.2    Michelson, A.M.3    Puget, K.4
  • 71
    • 0028066981 scopus 로고
    • Successful treatment of radiation-induced fibrosis using liposomal Cu/Zn superoxide dismutase: clinical trial
    • Delanian S., Baillet F., Huart J., Lefaix J.L., Maulard C., Housset M. Successful treatment of radiation-induced fibrosis using liposomal Cu/Zn superoxide dismutase: clinical trial. Radiother Oncol 1994, 32:12-20.
    • (1994) Radiother Oncol , vol.32 , pp. 12-20
    • Delanian, S.1    Baillet, F.2    Huart, J.3    Lefaix, J.L.4    Maulard, C.5    Housset, M.6
  • 72
    • 0028801716 scopus 로고
    • Pentoxifylline, pentifylline, and interferons decrease type I and III procollagen mRNA levels in dermal fibroblasts: evidence for mediation by nuclear factor 1 down-regulation
    • Duncan M.R., Hasan A., Berman B. Pentoxifylline, pentifylline, and interferons decrease type I and III procollagen mRNA levels in dermal fibroblasts: evidence for mediation by nuclear factor 1 down-regulation. J Invest Dermatol 1995, 104:282-286.
    • (1995) J Invest Dermatol , vol.104 , pp. 282-286
    • Duncan, M.R.1    Hasan, A.2    Berman, B.3
  • 73
    • 7944220853 scopus 로고    scopus 로고
    • The radiation-induced fibroatrophic process: therapeutic perspective via the antioxidant pathway
    • Delanian S., Lefaix J.L. The radiation-induced fibroatrophic process: therapeutic perspective via the antioxidant pathway. Radiother Oncol 2004, 73:119-131.
    • (2004) Radiother Oncol , vol.73 , pp. 119-131
    • Delanian, S.1    Lefaix, J.L.2
  • 74
    • 0038352140 scopus 로고    scopus 로고
    • Randomized, placebo-controlled trial of combined pentoxifylline and tocopherol for regression of superficial radiation-induced fibrosis
    • Delanian S., Porcher R., Balla-Mekias S., Lefaix J.L. Randomized, placebo-controlled trial of combined pentoxifylline and tocopherol for regression of superficial radiation-induced fibrosis. J Clin Oncol 2003, 21:2545-2550.
    • (2003) J Clin Oncol , vol.21 , pp. 2545-2550
    • Delanian, S.1    Porcher, R.2    Balla-Mekias, S.3    Lefaix, J.L.4
  • 75
    • 33644842542 scopus 로고    scopus 로고
    • Kinetics of response to long-term treatment combining pentoxifylline and tocopherol in patients with superficial radiation-induced fibrosis
    • Delanian S., Porcher R., Rudant J., Lefaix J.L. Kinetics of response to long-term treatment combining pentoxifylline and tocopherol in patients with superficial radiation-induced fibrosis. J Clin Oncol 2005, 23:8570-8579.
    • (2005) J Clin Oncol , vol.23 , pp. 8570-8579
    • Delanian, S.1    Porcher, R.2    Rudant, J.3    Lefaix, J.L.4
  • 77
    • 79957578310 scopus 로고    scopus 로고
    • Complete restoration of refractory mandibular osteoradionecrosis by prolonged treatment with a pentoxifylline-tocopherol-clodronate combination (PENTOCLO): a Phase II trial
    • [Epub ahead of print]
    • Delanian S., Chatel C., Porcher R., Depondt J., Lefaix J.L. Complete restoration of refractory mandibular osteoradionecrosis by prolonged treatment with a pentoxifylline-tocopherol-clodronate combination (PENTOCLO): a Phase II trial. Int J Radiat Oncol Biol Phys 2010, [Epub ahead of print]. http://dx.doi.org/10.1016/j.ijrobp.2010.03.029.
    • (2010) Int J Radiat Oncol Biol Phys
    • Delanian, S.1    Chatel, C.2    Porcher, R.3    Depondt, J.4    Lefaix, J.L.5
  • 78
    • 55649121083 scopus 로고    scopus 로고
    • Significant clinical improvement in radiation-induced lumbosacral polyradiculopathy by a treatment combining pentoxifylline, tocopherol, and clodronate (Pentoclo)
    • Delanian S., Lefaix J.L., Maisonobe T., Salachas F., Pradat P.F. Significant clinical improvement in radiation-induced lumbosacral polyradiculopathy by a treatment combining pentoxifylline, tocopherol, and clodronate (Pentoclo). J Neurol Sci 2008, 275:164-166.
    • (2008) J Neurol Sci , vol.275 , pp. 164-166
    • Delanian, S.1    Lefaix, J.L.2    Maisonobe, T.3    Salachas, F.4    Pradat, P.F.5
  • 80
    • 22444451354 scopus 로고    scopus 로고
    • Phase II study of vitamin E and pentoxifylline in patients with late side effects of pelvic radiotherapy
    • Gothard L., Cornes P., Brooker S., Earl J., Glees J., Hall E., et al. Phase II study of vitamin E and pentoxifylline in patients with late side effects of pelvic radiotherapy. Radiother Oncol 2005, 75:334-341.
    • (2005) Radiother Oncol , vol.75 , pp. 334-341
    • Gothard, L.1    Cornes, P.2    Brooker, S.3    Earl, J.4    Glees, J.5    Hall, E.6
  • 81
    • 7944225103 scopus 로고    scopus 로고
    • Double-blind placebo-controlled randomised trial of vitamin E and pentoxifylline in patients with chronic arm lymphoedema and fibrosis after surgery and radiotherapy for breast cancer
    • Gothard L., Cornes P., Earl J., MacLaren J., Mortimer P., Peacock J., et al. Double-blind placebo-controlled randomised trial of vitamin E and pentoxifylline in patients with chronic arm lymphoedema and fibrosis after surgery and radiotherapy for breast cancer. Radiother Oncol 2004, 73:133-139.
    • (2004) Radiother Oncol , vol.73 , pp. 133-139
    • Gothard, L.1    Cornes, P.2    Earl, J.3    MacLaren, J.4    Mortimer, P.5    Peacock, J.6
  • 82
    • 21244496787 scopus 로고    scopus 로고
    • Modulation of DNA damage by pentoxifylline and alpha-tocopherol in skin fibroblasts exposed to Gamma rays
    • Laurent C., Pouget J.P., Voisin P. Modulation of DNA damage by pentoxifylline and alpha-tocopherol in skin fibroblasts exposed to Gamma rays. Radiat Res 2005, 164:63-72.
    • (2005) Radiat Res , vol.164 , pp. 63-72
    • Laurent, C.1    Pouget, J.P.2    Voisin, P.3
  • 83
    • 33745304382 scopus 로고    scopus 로고
    • DNA damage in cultured skin microvascular endothelial cells exposed to gamma rays and treated by the combination pentoxifylline and alpha-tocopherol
    • Laurent C., Voisin P., Pouget J.P. DNA damage in cultured skin microvascular endothelial cells exposed to gamma rays and treated by the combination pentoxifylline and alpha-tocopherol. Int J Radiat Biol 2006, 82:309-321.
    • (2006) Int J Radiat Biol , vol.82 , pp. 309-321
    • Laurent, C.1    Voisin, P.2    Pouget, J.P.3
  • 84
    • 0027565081 scopus 로고
    • La fibrose iatrogénique en cancérologie (2e partie): principales étiologies et possibilités thérapeutiques
    • Delanian S., Lefaix J.L., Housset M. La fibrose iatrogénique en cancérologie (2e partie): principales étiologies et possibilités thérapeutiques. Bull Cancer 1993, 80:202-212.
    • (1993) Bull Cancer , vol.80 , pp. 202-212
    • Delanian, S.1    Lefaix, J.L.2    Housset, M.3
  • 85
    • 0027253082 scopus 로고
    • Amelioration of radiation nephropathy in rats by dexamethasone treatment after irradiation
    • Geraci J.P., Mariano M.S., Jackson K.L. Amelioration of radiation nephropathy in rats by dexamethasone treatment after irradiation. Radiat Res 1993, 134:86-93.
    • (1993) Radiat Res , vol.134 , pp. 86-93
    • Geraci, J.P.1    Mariano, M.S.2    Jackson, K.L.3
  • 86
    • 0026403409 scopus 로고
    • Effects of some nonsteroidal anti-inflammatory agents on experimental radiation pneumonitis
    • Gross N.J., Holloway N.O., Narine K.R. Effects of some nonsteroidal anti-inflammatory agents on experimental radiation pneumonitis. Radiat Res 1991, 127:317-324.
    • (1991) Radiat Res , vol.127 , pp. 317-324
    • Gross, N.J.1    Holloway, N.O.2    Narine, K.R.3
  • 87
    • 0028289621 scopus 로고
    • On radiation damage to normal tissues and its treatment. II. Anti-inflammatory drugs
    • Michalowski A.S. On radiation damage to normal tissues and its treatment. II. Anti-inflammatory drugs. Acta Oncol 1994, 33:139-157.
    • (1994) Acta Oncol , vol.33 , pp. 139-157
    • Michalowski, A.S.1
  • 88
    • 0034749010 scopus 로고    scopus 로고
    • Hyperbaric oxygen: an effective tool to treat radiation morbidity in prostate cancer
    • Mayer R., Klemen H., Quehenberger F., Sankin O., Mayer E., Hackl A., et al. Hyperbaric oxygen: an effective tool to treat radiation morbidity in prostate cancer. Radiother Oncol 2001, 61:151-156.
    • (2001) Radiother Oncol , vol.61 , pp. 151-156
    • Mayer, R.1    Klemen, H.2    Quehenberger, F.3    Sankin, O.4    Mayer, E.5    Hackl, A.6
  • 89
    • 3242677117 scopus 로고    scopus 로고
    • Hyperbaric oxygen therapy in the treatment of radio-induced lesions in normal tissues: a literature review
    • Pasquier D., Hoelscher T., Schmutz J., Dische S., Mathieu D., Baumann M., et al. Hyperbaric oxygen therapy in the treatment of radio-induced lesions in normal tissues: a literature review. Radiother Oncol 2004, 72:1-13.
    • (2004) Radiother Oncol , vol.72 , pp. 1-13
    • Pasquier, D.1    Hoelscher, T.2    Schmutz, J.3    Dische, S.4    Mathieu, D.5    Baumann, M.6
  • 90
    • 79961210073 scopus 로고    scopus 로고
    • Attenuation and reversal of radiation-induced pulmonary fibrosis in a murine model by an Anti-CTGF monoclonal antibody
    • Bickelhaupt S., Peschke P., Erbel C., Tietz A., Timke C., Wirkner U., et al. Attenuation and reversal of radiation-induced pulmonary fibrosis in a murine model by an Anti-CTGF monoclonal antibody. Int J Radiat Oncol Biol Phys 2010, 78:S40.
    • (2010) Int J Radiat Oncol Biol Phys , vol.78
    • Bickelhaupt, S.1    Peschke, P.2    Erbel, C.3    Tietz, A.4    Timke, C.5    Wirkner, U.6
  • 91
    • 65649091292 scopus 로고    scopus 로고
    • Molecular aspects of intestinal radiation-induced fibrosis
    • Gervaz P., Morel P., Vozenin-Brotons M.C. Molecular aspects of intestinal radiation-induced fibrosis. Curr Mol Med 2009, 9:273-280.
    • (2009) Curr Mol Med , vol.9 , pp. 273-280
    • Gervaz, P.1    Morel, P.2    Vozenin-Brotons, M.C.3
  • 92
    • 79952547870 scopus 로고    scopus 로고
    • Modulation of the Rho/ROCK Pathway in heart and lung after thorax irradiation reveals targets to improve normal tissue toxicity. Curr Drug Targets
    • Monceau V, Pasinetti N, Schupp C, Pouzoulet F, Opolon P, Vozenin MC. Modulation of the Rho/ROCK Pathway in heart and lung after thorax irradiation reveals targets to improve normal tissue toxicity. Curr Drug Targets 2010;11:1395-404.
    • (2010) , vol.11 , pp. 1395-404
    • Monceau, V.1    Pasinetti, N.2    Schupp, C.3    Pouzoulet, F.4    Opolon, P.5    Vozenin, M.C.6
  • 93
    • 19444379395 scopus 로고    scopus 로고
    • Pravastatin limits endothelial activation after irradiation and decreases the resulting inflammatory and thrombotic responses
    • Gaugler M.H., Vereycken-Holler V., Squiban C., Vandamme M., Vozenin-Brotons M.C., Benderitter M. Pravastatin limits endothelial activation after irradiation and decreases the resulting inflammatory and thrombotic responses. Radiat Res 2005, 163:479-487.
    • (2005) Radiat Res , vol.163 , pp. 479-487
    • Gaugler, M.H.1    Vereycken-Holler, V.2    Squiban, C.3    Vandamme, M.4    Vozenin-Brotons, M.C.5    Benderitter, M.6
  • 95
    • 10744233133 scopus 로고    scopus 로고
    • Statins increase thrombomodulin expression and function in human endothelial cells by a nitric oxide-dependent mechanism and counteract tumor necrosis factor alpha-induced thrombomodulin downregulation
    • Shi J., Wang J., Zheng H., Ling W., Joseph J., Li D., et al. Statins increase thrombomodulin expression and function in human endothelial cells by a nitric oxide-dependent mechanism and counteract tumor necrosis factor alpha-induced thrombomodulin downregulation. Blood Coagul Fibrinolysis 2003, 14:575-585.
    • (2003) Blood Coagul Fibrinolysis , vol.14 , pp. 575-585
    • Shi, J.1    Wang, J.2    Zheng, H.3    Ling, W.4    Joseph, J.5    Li, D.6
  • 96
    • 34447250540 scopus 로고    scopus 로고
    • Significance of endothelial dysfunction in the pathogenesis of early and delayed radiation enteropathy
    • Wang J., Boerma M., Fu Q., Hauer-Jensen M. Significance of endothelial dysfunction in the pathogenesis of early and delayed radiation enteropathy. World J Gastroenterol 2007, 13:3047-3055.
    • (2007) World J Gastroenterol , vol.13 , pp. 3047-3055
    • Wang, J.1    Boerma, M.2    Fu, Q.3    Hauer-Jensen, M.4
  • 97
    • 34547429997 scopus 로고    scopus 로고
    • Simvastatin ameliorates radiation enteropathy development after localized, fractionated irradiation by a protein C-independent mechanism
    • Wang J., Boerma M., Fu Q., Kulkarni A., Fink L.M., Hauer-Jensen M. Simvastatin ameliorates radiation enteropathy development after localized, fractionated irradiation by a protein C-independent mechanism. Int J Radiat Oncol Biol Phys 2007, 68:1483-1490.
    • (2007) Int J Radiat Oncol Biol Phys , vol.68 , pp. 1483-1490
    • Wang, J.1    Boerma, M.2    Fu, Q.3    Kulkarni, A.4    Fink, L.M.5    Hauer-Jensen, M.6
  • 98
    • 3042763035 scopus 로고    scopus 로고
    • Effect of administration of lovastatin on the development of late pulmonary effects after whole-lung irradiation in a murine model
    • Williams J.P., Hernady E., Johnston C.J., Reed C.M., Fenton B., Okunieff P., et al. Effect of administration of lovastatin on the development of late pulmonary effects after whole-lung irradiation in a murine model. Radiat Res 2004, 161:560-567.
    • (2004) Radiat Res , vol.161 , pp. 560-567
    • Williams, J.P.1    Hernady, E.2    Johnston, C.J.3    Reed, C.M.4    Fenton, B.5    Okunieff, P.6
  • 99
    • 33746370379 scopus 로고    scopus 로고
    • La chimiothérapie concomitante de la radiothérapie augmente la toxicité tardive après chirurgie conservatrice du cancer du sein
    • Toledano A., Garaud P., Serin D., Fourquet A., Bosset J.F., Miny-Buffet J., et al. La chimiothérapie concomitante de la radiothérapie augmente la toxicité tardive après chirurgie conservatrice du cancer du sein. Cancer Radiother 2006, 10:158-167.
    • (2006) Cancer Radiother , vol.10 , pp. 158-167
    • Toledano, A.1    Garaud, P.2    Serin, D.3    Fourquet, A.4    Bosset, J.F.5    Miny-Buffet, J.6


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