메뉴 건너뛰기




Volumn 85, Issue 16, 2011, Pages 7965-7975

The HIV-1-specific protein Casp8p41 induces death of infected cells through Bax/Bak

Author keywords

[No Author keywords available]

Indexed keywords

CASP8P41 PROTEIN; CASPASE 9; CD4 ANTIGEN; GREEN FLUORESCENT PROTEIN; PROTEIN BAK; PROTEIN BAX; UNCLASSIFIED DRUG; VIRUS PROTEIN;

EID: 79961185599     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02515-10     Document Type: Article
Times cited : (27)

References (67)
  • 1
    • 85056026629 scopus 로고    scopus 로고
    • Analysis of HIV protease killing through caspase 8 reveals a novel interaction between caspase 8 and mitochondria
    • Algeciras-Schimnich, A., et al. 2007. Analysis of HIV protease killing through caspase 8 reveals a novel interaction between caspase 8 and mitochondria. Open Virol. J. 1:39-46.
    • (2007) Open Virol. J. , vol.1 , pp. 39-46
    • Algeciras-Schimnich, A.1
  • 2
    • 0034099598 scopus 로고    scopus 로고
    • Production and pro-apoptotic activity of soluble CD95 ligand in pancreatic carcinoma
    • Bellone, G., et al. 2000. Production and pro-apoptotic activity of soluble CD95 ligand in pancreatic carcinoma. Clin. Cancer Res. 6:2448-2455.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 2448-2455
    • Bellone, G.1
  • 3
    • 47749152622 scopus 로고    scopus 로고
    • Infected cell killing by HIV-1 protease promotes NF-kappaB dependent HIV-1 replication
    • Bren, G. D., et al. 2008. Infected cell killing by HIV-1 protease promotes NF-kappaB dependent HIV-1 replication. PLoS One 3:e2112.
    • (2008) PLoS One , vol.3
    • Bren, G.D.1
  • 4
    • 9144261631 scopus 로고    scopus 로고
    • T-cell subsets that harbor human immunodeficiency virus (HIV) in vivo: implications for HIV pathogenesis
    • Brenchley, J. M., et al. 2004. T-cell subsets that harbor human immunodeficiency virus (HIV) in vivo: implications for HIV pathogenesis. J. Virol. 78:1160-1168.
    • (2004) J. Virol. , vol.78 , pp. 1160-1168
    • Brenchley, J.M.1
  • 5
    • 4644342929 scopus 로고    scopus 로고
    • CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract
    • Brenchley, J. M., et al. 2004. CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract. J. Exp. Med. 200:749-759.
    • (2004) J. Exp. Med. , vol.200 , pp. 749-759
    • Brenchley, J.M.1
  • 6
    • 0034058683 scopus 로고    scopus 로고
    • Distinct stages of cytochrome c release from mitochondria: evidence for a feedback amplification loop linking caspase activation to mitochondrial dysfunction in genotoxic stress induced apoptosis
    • Chen, Q., B. Gong, and A. Almasan. 2000. Distinct stages of cytochrome c release from mitochondria: evidence for a feedback amplification loop linking caspase activation to mitochondrial dysfunction in genotoxic stress induced apoptosis. Cell Death Differ. 7:227-233.
    • (2000) Cell Death Differ , vol.7 , pp. 227-233
    • Chen, Q.1    Gong, B.2    Almasan, A.3
  • 7
    • 0031465443 scopus 로고    scopus 로고
    • Conversion of Bcl-2 to a Bax-like death effector by caspases
    • Cheng, E. H., et al. 1997. Conversion of Bcl-2 to a Bax-like death effector by caspases. Science 278:1966-1968.
    • (1997) Science , vol.278 , pp. 1966-1968
    • Cheng, E.H.1
  • 8
    • 0031058025 scopus 로고    scopus 로고
    • The inhibition of pro-apoptotic ICE-like proteases enhances HIV replication
    • Chinnaiyan, A. M., C. Woffendin, V. M. Dixit, and G. J. Nabel. 1997. The inhibition of pro-apoptotic ICE-like proteases enhances HIV replication. Nat. Med. 3:333-337.
    • (1997) Nat. Med. , vol.3 , pp. 333-337
    • Chinnaiyan, A.M.1    Woffendin, C.2    Dixit, V.M.3    Nabel, G.J.4
  • 9
    • 0030913366 scopus 로고    scopus 로고
    • Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection
    • Chun, T. W., et al. 1997. Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection. Nature 387:183-188.
    • (1997) Nature , vol.387 , pp. 183-188
    • Chun, T.W.1
  • 10
    • 0026731468 scopus 로고
    • Rectal mucosal pathology varies with human immunodeficiency virus antigen content and disease stage
    • Clayton, F., et al. 1992. Rectal mucosal pathology varies with human immunodeficiency virus antigen content and disease stage. Gastroenterology 103: 919-933.
    • (1992) Gastroenterology , vol.103 , pp. 919-933
    • Clayton, F.1
  • 11
    • 0031023132 scopus 로고    scopus 로고
    • Selective depletion of rectal lamina propria rather than lymphoid aggregate CD4 lymphocytes in HIV infection
    • Clayton, F., G. Snow, S. Reka, and D. P. Kotler. 1997. Selective depletion of rectal lamina propria rather than lymphoid aggregate CD4 lymphocytes in HIV infection. Clin. Exp. Immunol. 107:288-292.
    • (1997) Clin. Exp. Immunol. , vol.107 , pp. 288-292
    • Clayton, F.1    Snow, G.2    Reka, S.3    Kotler, D.P.4
  • 12
    • 79957888573 scopus 로고    scopus 로고
    • Mechanisms of HIV-associated lymphocyte apoptosis: 2010
    • Cummins, N., and A. D. Badley. 2010. Mechanisms of HIV-associated lymphocyte apoptosis: 2010. Cell Death Dis. 1:e99.
    • (2010) Cell Death Dis , vol.1
    • Cummins, N.1    Badley, A.D.2
  • 13
    • 77954722968 scopus 로고    scopus 로고
    • Intracellular Casp8p41 content is inversely associated with CD4 T cell count
    • Cummins, N. W., et al. 2010. Intracellular Casp8p41 content is inversely associated with CD4 T cell count. J. Infect. Dis. 202:386-391.
    • (2010) J. Infect. Dis. , vol.202 , pp. 386-391
    • Cummins, N.W.1
  • 14
    • 0031032294 scopus 로고    scopus 로고
    • Bcl-2 and Bcl-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents
    • Decaudin, D., et al. 1997. Bcl-2 and Bcl-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents. Cancer Res. 57:62-67.
    • (1997) Cancer Res , vol.57 , pp. 62-67
    • Decaudin, D.1
  • 15
    • 0026543962 scopus 로고
    • Analysis and discrimination of necrosis and apoptosis (programmed cell death) by multiparameter flow cytometry
    • Dive, C., et al. 1992. Analysis and discrimination of necrosis and apoptosis (programmed cell death) by multiparameter flow cytometry. Biochim. Biophys. Acta 1133:275-285.
    • (1992) Biochim. Biophys. Acta , vol.1133 , pp. 275-285
    • Dive, C.1
  • 17
    • 0028912254 scopus 로고
    • Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes
    • Finkel, T. H., et al. 1995. Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes. Nat. Med. 1:129-134.
    • (1995) Nat. Med. , vol.1 , pp. 129-134
    • Finkel, T.H.1
  • 18
    • 58149201240 scopus 로고    scopus 로고
    • Cardiolipin provides an essential activating platform for caspase-8 on mitochondria
    • Gonzalvez, F., et al. 2008. Cardiolipin provides an essential activating platform for caspase-8 on mitochondria. J. Cell Biol. 183:681-696.
    • (2008) J. Cell Biol. , vol.183 , pp. 681-696
    • Gonzalvez, F.1
  • 19
    • 0038725688 scopus 로고    scopus 로고
    • Apoptosis as an HIV strategy to escape immune attack
    • Gougeon, M. L. 2003. Apoptosis as an HIV strategy to escape immune attack. Nat. Rev. Immunol. 3:392-404.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 392-404
    • Gougeon, M.L.1
  • 20
  • 21
    • 0142092389 scopus 로고    scopus 로고
    • Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy
    • Guadalupe, M., et al. 2003. Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy. J. Virol. 77:11708-11717.
    • (2003) J. Virol. , vol.77 , pp. 11708-11717
    • Guadalupe, M.1
  • 22
    • 0027755134 scopus 로고
    • Simian immunodeficiency virus infection of the gastrointestinal tract of rhesus macaques. Functional, pathological, and morphological changes
    • Heise, C., P. Vogel, C. J. Miller, C. H. Halsted, and S. Dandekar. 1993. Simian immunodeficiency virus infection of the gastrointestinal tract of rhesus macaques. Functional, pathological, and morphological changes. Am. J. Pathol. 142:1759-1771.
    • (1993) Am. J. Pathol. , vol.142 , pp. 1759-1771
    • Heise, C.1    Vogel, P.2    Miller, C.J.3    Halsted, C.H.4    Dandekar, S.5
  • 23
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengartner, M. O. 2000. The biochemistry of apoptosis. Nature 407:770-776.
    • (2000) Nature , vol.407 , pp. 770-776
    • Hengartner, M.O.1
  • 24
    • 0027932364 scopus 로고
    • The activity of the protease of human immunodeficiency virus type 1 is initiated at the membrane of infected cells before the release of viral proteins and is required for release to occur with maximum efficiency
    • Kaplan, A. H., M. Manchester, and R. Swanstrom. 1994. The activity of the protease of human immunodeficiency virus type 1 is initiated at the membrane of infected cells before the release of viral proteins and is required for release to occur with maximum efficiency. J. Virol. 68:6782-6786.
    • (1994) J. Virol. , vol.68 , pp. 6782-6786
    • Kaplan, A.H.1    Manchester, M.2    Swanstrom, R.3
  • 25
    • 0026048760 scopus 로고
    • The HIV-1 gag precursor is processed via two pathways: implications for cytotoxicity
    • Kaplan, A. H., and R. Swanstrom. 1991. The HIV-1 gag precursor is processed via two pathways: implications for cytotoxicity. Biomed. Biochim. Acta 50:647-653.
    • (1991) Biomed. Biochim. Acta , vol.50 , pp. 647-653
    • Kaplan, A.H.1    Swanstrom, R.2
  • 26
    • 0025828543 scopus 로고
    • Human immunodeficiency virus type 1 Gag proteins are processed in two cellular compartments
    • Kaplan, A. H., and R. Swanstrom. 1991. Human immunodeficiency virus type 1 Gag proteins are processed in two cellular compartments. Proc. Natl. Acad. Sci. U. S. A. 88:4528-4532.
    • (1991) Proc. Natl. Acad. Sci. U. S. A. , vol.88 , pp. 4528-4532
    • Kaplan, A.H.1    Swanstrom, R.2
  • 27
    • 70449091753 scopus 로고    scopus 로고
    • Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis
    • Kim, H., et al. 2009. Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis. Mol. Cell 36:487-499.
    • (2009) Mol. Cell , vol.36 , pp. 487-499
    • Kim, H.1
  • 28
    • 0027298094 scopus 로고
    • Intestinal mucosal inflammation associated with human immunodeficiency virus infection
    • Kotler, D. P., S. Reka, and F. Clayton. 1993. Intestinal mucosal inflammation associated with human immunodeficiency virus infection. Dig. Dis. Sci. 38: 1119-1127.
    • (1993) Dig. Dis. Sci. , vol.38 , pp. 1119-1127
    • Kotler, D.P.1    Reka, S.2    Clayton, F.3
  • 29
    • 33845977959 scopus 로고    scopus 로고
    • Mitochondrial membrane permeabilization in cell death
    • Kroemer, G., L. Galluzzi, and C. Brenner. 2007. Mitochondrial membrane permeabilization in cell death. Physiol. Rev. 87:99-163.
    • (2007) Physiol. Rev. , vol.87 , pp. 99-163
    • Kroemer, G.1    Galluzzi, L.2    Brenner, C.3
  • 30
    • 0032947858 scopus 로고    scopus 로고
    • Human intestinal lamina propria lymphocytes are naturally permissive to HIV-1 infection
    • Lapenta, C., et al. 1999. Human intestinal lamina propria lymphocytes are naturally permissive to HIV-1 infection. Eur. J. Immunol. 29:1202-1208.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 1202-1208
    • Lapenta, C.1
  • 31
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
    • Li, P., et al. 1997. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91:479-489.
    • (1997) Cell , vol.91 , pp. 479-489
    • Li, P.1
  • 32
    • 17844376742 scopus 로고    scopus 로고
    • Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells
    • Li, Q., et al. 2005. Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells. Nature 434:1148-1152.
    • (2005) Nature , vol.434 , pp. 1148-1152
    • Li, Q.1
  • 33
    • 0027315294 scopus 로고
    • Loss of mucosal CD4 lymphocytes is an early feature of HIV infection
    • Lim, S. G., et al. 1993. Loss of mucosal CD4 lymphocytes is an early feature of HIV infection. Clin. Exp. Immunol. 92:448-454.
    • (1993) Clin. Exp. Immunol. , vol.92 , pp. 448-454
    • Lim, S.G.1
  • 34
    • 33750358735 scopus 로고    scopus 로고
    • An essential role for LEDGF/p75 in HIV integration
    • Llano, M., et al. 2006. An essential role for LEDGF/p75 in HIV integration. Science 314:461-464.
    • (2006) Science , vol.314 , pp. 461-464
    • Llano, M.1
  • 35
    • 0032555716 scopus 로고    scopus 로고
    • Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
    • Luo, X., I. Budihardjo, H. Zou, C. Slaughter, and X. Wang. 1998. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 94:481-490.
    • (1998) Cell , vol.94 , pp. 481-490
    • Luo, X.1    Budihardjo, I.2    Zou, H.3    Slaughter, C.4    Wang, X.5
  • 36
    • 17844374605 scopus 로고    scopus 로고
    • Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection
    • Mattapallil, J. J., et al. 2005. Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection. Nature 434:1093-1097.
    • (2005) Nature , vol.434 , pp. 1093-1097
    • Mattapallil, J.J.1
  • 37
    • 0035912232 scopus 로고    scopus 로고
    • The dynamics of CD4+ T-cell depletion in HIV disease
    • McCune, J. M. 2001. The dynamics of CD4+ T-cell depletion in HIV disease. Nature 410:974-979.
    • (2001) Nature , vol.410 , pp. 974-979
    • McCune, J.M.1
  • 38
    • 0030925774 scopus 로고    scopus 로고
    • FLICE is activated by association with the CD95 death-inducing signaling complex (DISC)
    • Medema, J. P., et al. 1997. FLICE is activated by association with the CD95 death-inducing signaling complex (DISC). EMBO J. 16:2794-2804.
    • (1997) EMBO J , vol.16 , pp. 2794-2804
    • Medema, J.P.1
  • 39
    • 4644289983 scopus 로고    scopus 로고
    • Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract
    • Mehandru, S., et al. 2004. Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract. J. Exp. Med. 200:761-770.
    • (2004) J. Exp. Med. , vol.200 , pp. 761-770
    • Mehandru, S.1
  • 40
    • 33846034454 scopus 로고    scopus 로고
    • Mechanisms of gastrointestinal CD4+ T-cell depletion during acute and early human immunodeficiency virus type 1 infection
    • Mehandru, S., et al. 2007. Mechanisms of gastrointestinal CD4+ T-cell depletion during acute and early human immunodeficiency virus type 1 infection. J. Virol. 81:599-612.
    • (2007) J. Virol. , vol.81 , pp. 599-612
    • Mehandru, S.1
  • 41
    • 0030324952 scopus 로고    scopus 로고
    • A pathway of multi-chaperone interactions common to diverse regulatory proteins: estrogen receptor, Fes tyrosine kinase, heat shock transcription factor Hsf1, and the aryl hydrocarbon receptor
    • Nair, S. C., et al. 1996. A pathway of multi-chaperone interactions common to diverse regulatory proteins: estrogen receptor, Fes tyrosine kinase, heat shock transcription factor Hsf1, and the aryl hydrocarbon receptor. Cell Stress Chaperones 1:237-250.
    • (1996) Cell Stress Chaperones , vol.1 , pp. 237-250
    • Nair, S.C.1
  • 42
    • 79251523843 scopus 로고    scopus 로고
    • Patients with discordant responses to antiretroviral therapy have impaired killing of HIV-infected T cells
    • Natesampillai, S., Z. Nie, N. W. Cummins, G. D. Bren, and D. Jocmans. 2010. Patients with discordant responses to antiretroviral therapy have impaired killing of HIV-infected T cells. PLoS Pathog. 6:e1001213.
    • (2010) PLoS Pathog , vol.6
    • Natesampillai, S.1    Nie, Z.2    Cummins, N.W.3    Bren, G.D.4    Jocmans, D.5
  • 43
    • 85056069157 scopus 로고    scopus 로고
    • HIV protease cleavage of procaspase 8 is necessary for death of HIV-infected cells
    • Nie, Z., G. D. Bren, S. A. Rizza, and A. D. Badley. 2008. HIV protease cleavage of procaspase 8 is necessary for death of HIV-infected cells. Open Virol. J. 2:1-7.
    • (2008) Open Virol. J. , vol.2 , pp. 1-7
    • Nie, Z.1    Bren, G.D.2    Rizza, S.A.3    Badley, A.D.4
  • 44
    • 34250881463 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 protease cleaves procaspase 8 in vivo
    • Nie, Z., et al. 2007. Human immunodeficiency virus type 1 protease cleaves procaspase 8 in vivo. J. Virol. 81:6947-6956.
    • (2007) J. Virol. , vol.81 , pp. 6947-6956
    • Nie, Z.1
  • 45
    • 9244220630 scopus 로고    scopus 로고
    • Insufficient production and tissue delivery of CD4+ memory T cells in rapidly progressive simian immunodeficiency virus infection
    • Picker, L. J., et al. 2004. Insufficient production and tissue delivery of CD4+ memory T cells in rapidly progressive simian immunodeficiency virus infection. J. Exp. Med. 200:1299-1314.
    • (2004) J. Exp. Med. , vol.200 , pp. 1299-1314
    • Picker, L.J.1
  • 46
    • 0034888099 scopus 로고    scopus 로고
    • A preponderance of CCR5(+) CXCR4(+) mononuclear cells enhances gastrointestinal mucosal susceptibility to human immunodeficiency virus type 1 infection
    • Poles, M. A., J. Elliott, P. Taing, P. A. Anton, and I. S. Chen. 2001. A preponderance of CCR5(+) CXCR4(+) mononuclear cells enhances gastrointestinal mucosal susceptibility to human immunodeficiency virus type 1 infection. J. Virol. 75:8390-8399.
    • (2001) J. Virol. , vol.75 , pp. 8390-8399
    • Poles, M.A.1    Elliott, J.2    Taing, P.3    Anton, P.A.4    Chen, I.S.5
  • 47
    • 0035896592 scopus 로고    scopus 로고
    • Pro-caspase-8 is predominantly localized in mitochondria and released into cytoplasm upon apoptotic stimulation
    • Qin, Z. H., et al. 2001. Pro-caspase-8 is predominantly localized in mitochondria and released into cytoplasm upon apoptotic stimulation. J. Biol. Chem. 276:8079-8086.
    • (2001) J. Biol. Chem. , vol.276 , pp. 8079-8086
    • Qin, Z.H.1
  • 48
    • 33749551653 scopus 로고    scopus 로고
    • Loss of caspase-9 provides genetic evidence for the type I/II concept of CD95-mediated apoptosis
    • Samraj, A. K., E. Keil, N. Ueffing, K. Schulze-Osthoff, and I. Schmitz. 2006. Loss of caspase-9 provides genetic evidence for the type I/II concept of CD95-mediated apoptosis. J. Biol. Chem. 281:29652-29659.
    • (2006) J. Biol. Chem. , vol.281 , pp. 29652-29659
    • Samraj, A.K.1    Keil, E.2    Ueffing, N.3    Schulze-Osthoff, K.4    Schmitz, I.5
  • 49
    • 22244451393 scopus 로고    scopus 로고
    • Gut mucosal T cell responses and gene expression correlate with protection against disease in long-term HIV-1-infected nonprogressors
    • Sankaran, S., et al. 2005. Gut mucosal T cell responses and gene expression correlate with protection against disease in long-term HIV-1-infected nonprogressors. Proc. Natl. Acad. Sci. U. S. A. 102:9860-9865.
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 9860-9865
    • Sankaran, S.1
  • 50
    • 0028811367 scopus 로고
    • Loss of CD4 T lymphocytes in patients infected with human immunodeficiency virus type 1 is more pronounced in the duodenal mucosa than in the peripheral blood. Berlin Diarrhea/Wasting Syndrome Study Group
    • Schneider, T., et al. 1995. Loss of CD4 T lymphocytes in patients infected with human immunodeficiency virus type 1 is more pronounced in the duodenal mucosa than in the peripheral blood. Berlin Diarrhea/Wasting Syndrome Study Group. Gut 37:524-529.
    • (1995) Gut , vol.37 , pp. 524-529
    • Schneider, T.1
  • 51
    • 0038033158 scopus 로고    scopus 로고
    • Trafficking of human immunodeficiency virus type 1-specific CD8+ T cells to gut-associated lymphoid tissue during chronic infection
    • Shacklett, B. L., et al. 2003. Trafficking of human immunodeficiency virus type 1-specific CD8+ T cells to gut-associated lymphoid tissue during chronic infection. J. Virol. 77:5621-5631.
    • (2003) J. Virol. , vol.77 , pp. 5621-5631
    • Shacklett, B.L.1
  • 52
    • 1442335318 scopus 로고    scopus 로고
    • Control of mitochondrial permeability by Bcl-2 family members
    • Sharpe, J. C., D. Arnoult, and R. J. Youle. 2004. Control of mitochondrial permeability by Bcl-2 family members. Biochim. Biophys. Acta 1644:107-113.
    • (2004) Biochim. Biophys. Acta , vol.1644 , pp. 107-113
    • Sharpe, J.C.1    Arnoult, D.2    Youle, R.J.3
  • 53
    • 0027941411 scopus 로고
    • Quantitative analysis of mononuclear cells expressing human immunodeficiency virus type 1 RNA in esophageal mucosa
    • Smith, P. D., C. H. Fox, H. Masur, H. S. Winter, and D. W. Alling. 1994. Quantitative analysis of mononuclear cells expressing human immunodeficiency virus type 1 RNA in esophageal mucosa. J. Exp. Med. 180:1541-1546.
    • (1994) J. Exp. Med. , vol.180 , pp. 1541-1546
    • Smith, P.D.1    Fox, C.H.2    Masur, H.3    Winter, H.S.4    Alling, D.W.5
  • 54
    • 0031925896 scopus 로고    scopus 로고
    • Gastrointestinal T lymphocytes retain high potential for cytokine responses but have severe CD4(+) T-cell depletion at all stages of simian immunodeficiency virus infection compared to peripheral lymphocytes
    • Smit-McBride, Z., J. J. Mattapallil, M. McChesney, D. Ferrick, and S. Dandekar. 1998. Gastrointestinal T lymphocytes retain high potential for cytokine responses but have severe CD4(+) T-cell depletion at all stages of simian immunodeficiency virus infection compared to peripheral lymphocytes. J. Virol. 72:6646-6656.
    • (1998) J. Virol. , vol.72 , pp. 6646-6656
    • Smit-McBride, Z.1    Mattapallil, J.J.2    McChesney, M.3    Ferrick, D.4    Dandekar, S.5
  • 55
    • 0035469857 scopus 로고    scopus 로고
    • Growth factor withdrawal from primary human erythroid progenitors induces apoptosis through a pathway involving glycogen synthase kinase-3 and Bax
    • Somervaille, T. C., D. C. Linch, and A. Khwaja. 2001. Growth factor withdrawal from primary human erythroid progenitors induces apoptosis through a pathway involving glycogen synthase kinase-3 and Bax. Blood 98:1374-1381.
    • (2001) Blood , vol.98 , pp. 1374-1381
    • Somervaille, T.C.1    Linch, D.C.2    Khwaja, A.3
  • 56
    • 0031027528 scopus 로고    scopus 로고
    • Quantitative detection of immune activation transcripts as a diagnostic tool in kidney transplantation
    • Strehlau, J., et al. 1997. Quantitative detection of immune activation transcripts as a diagnostic tool in kidney transplantation. Proc. Natl. Acad. Sci. U. S. A. 94:695-700.
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 695-700
    • Strehlau, J.1
  • 57
    • 0021799744 scopus 로고
    • Bacterial translocation and gram-negative bacteremia in patients with hematological malignancies
    • Tancrede, C. H., and A. O. Andremont. 1985. Bacterial translocation and gram-negative bacteremia in patients with hematological malignancies. J. Infect. Dis. 152:99-103.
    • (1985) J. Infect. Dis. , vol.152 , pp. 99-103
    • Tancrede, C.H.1    Andremont, A.O.2
  • 58
    • 77952958686 scopus 로고    scopus 로고
    • Casp8p41 expression in primary T cells induces a proinflammatory response
    • Taylor, J. A., et al. 2010. Casp8p41 expression in primary T cells induces a proinflammatory response. AIDS 24:1251-1258.
    • (2010) AIDS , vol.24 , pp. 1251-1258
    • Taylor, J.A.1
  • 59
  • 60
    • 0026631292 scopus 로고
    • Enteric immunologic abnormalities in human immunodeficiency virus infection
    • Ullrich, R., M. Zeitz, and E. O. Riecken. 1992. Enteric immunologic abnormalities in human immunodeficiency virus infection. Semin. Liver Dis. 12: 167-174.
    • (1992) Semin. Liver Dis. , vol.12 , pp. 167-174
    • Ullrich, R.1    Zeitz, M.2    Riecken, E.O.3
  • 61
    • 0032540418 scopus 로고    scopus 로고
    • Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection
    • Veazey, R. S., et al. 1998. Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection. Science 280:427-431.
    • (1998) Science , vol.280 , pp. 427-431
    • Veazey, R.S.1
  • 62
    • 33749660845 scopus 로고    scopus 로고
    • A stapled BID BH3 helix directly binds and activates BAX
    • Walensky, L. D., et al. 2006. A stapled BID BH3 helix directly binds and activates BAX. Mol. Cell 24:199-210.
    • (2006) Mol. Cell , vol.24 , pp. 199-210
    • Walensky, L.D.1
  • 63
    • 0034602776 scopus 로고    scopus 로고
    • The Nef protein of HIV-1 associates with rafts and primes T cells for activation
    • Wang, J. K., E. Kiyokawa, E. Verdin, and D. Trono. 2000. The Nef protein of HIV-1 associates with rafts and primes T cells for activation. Proc. Natl. Acad. Sci. U. S. A. 97:394-399.
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 394-399
    • Wang, J.K.1    Kiyokawa, E.2    Verdin, E.3    Trono, D.4
  • 64
    • 0035957653 scopus 로고    scopus 로고
    • Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death
    • Wei, M. C., et al. 2001. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 292:727-730.
    • (2001) Science , vol.292 , pp. 727-730
    • Wei, M.C.1
  • 65
    • 15444373128 scopus 로고    scopus 로고
    • Specific cleavage of Mcl-1 by caspase-3 in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in Jurkat leukemia T cells
    • Weng, C., Y. Li, D. Xu, Y. Shi, and H. Tang. 2005. Specific cleavage of Mcl-1 by caspase-3 in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in Jurkat leukemia T cells. J. Biol. Chem. 280: 10491-10500.
    • (2005) J. Biol. Chem. , vol.280 , pp. 10491-10500
    • Weng, C.1    Li, Y.2    Xu, D.3    Shi, Y.4    Tang, H.5
  • 66
    • 33846964621 scopus 로고    scopus 로고
    • Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak
    • Willis, S. N., et al. 2007. Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak. Science 315:856-859.
    • (2007) Science , vol.315 , pp. 856-859
    • Willis, S.N.1
  • 67
    • 37549048249 scopus 로고    scopus 로고
    • The BCL-2 protein family: opposing activities that mediate cell death
    • Youle, R. J., and A. Strasser. 2008. The BCL-2 protein family: opposing activities that mediate cell death. Nat. Rev. Mol. Cell Biol. 9:47-59.
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 47-59
    • Youle, R.J.1    Strasser, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.