Evaluation of influence of Ap4A analogues on Fhit-positive HEK293T cells; Cytotoxicity and ability to induce apoptosis

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 16, 2011, Pages 5053-5060

  Krakowiak, Agnieszka ^a   Pcherzewska, Róa ^a   Kaczmarek, Renata ^a   Tomaszewska, Agnieszka ^a   Nawrot, Barbara ^a   Stec, Wojciech J ^a  

^a CENTRE OF MOLECULAR AND MACROMOLECULAR STUDIES   (Poland)

Author keywords

Apoptosis; Diadenosine polyphosphate analogues; Diadenosine tetraphosphate (Ap4A); Diadenosine triphosphate (Ap3A); Fhit (fragile histidine triad)

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; DIADENOSINE POLYPHOSPHATE; FLUORESCEIN; FRAGILE HISTIDINE TRIAD PROTEIN; FRAGILE HISTIDINE TRIAD PROTEIN INHIBITOR; GLYCEROL; LIPOCORTIN 5; PHOSPHOROTHIOIC ACID; PROTEIN INHIBITOR; PYROPHOSPHATE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ACID ANHYDRIDE HYDROLASE; ANTINEOPLASTIC AGENT; CASPASE; CYTOTOXIN; DIADENOSINE POLYPHOSPHATE HYDROLASE; DIADENOSINE TETRAPHOSPHATE; DINUCLEOSIDE PHOSPHATE; FLUORESCENT DYE; TUMOR PROTEIN;

APOPTOSIS; ARTICLE; CELL STRAIN HEK293; CELL TRANSPORT; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENZYME ACTIVITY; GENE SILENCING; GENE THERAPY; HUMAN; HUMAN CELL; HUMAN TISSUE; IC 50; RNA INTERFERENCE; TRANSGENE; CELL SURVIVAL; CHEMISTRY; DOSE RESPONSE; DRUG EFFECT; DRUG SCREENING; FEMALE; GENETICS; METABOLISM; NEOPLASM; PATHOLOGY; PHYSIOLOGY; SYNTHESIS; TUMOR CELL LINE; TUMOR SUPPRESSOR GENE;

ACID ANHYDRIDE HYDROLASES; ANNEXIN A5; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASES; CELL LINE, TUMOR; CELL SURVIVAL; CYTOTOXINS; DINUCLEOSIDE PHOSPHATES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; FLUORESCENT DYES; GENES, TUMOR SUPPRESSOR; HEK293 CELLS; HUMANS; NEOPLASM PROTEINS; NEOPLASMS; RNA, SMALL INTERFERING;

EID: 79961167122     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2011.06.028     Document Type: Article

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