Characterization of a diadenosine tetraphosphate-receptor distinct from the ATP-purinoceptor in human tracheal gland cells

European Journal of Pharmacology

Volumn 384, Issue 1, 1999, Pages 91-98

  Saleh, Ali ^a   Picher, Maryse ^b   Kammouni, Wafa ^a   Figarella, Catherine ^a   Merten, Marc D ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Airway; Ap4A; Nucleotide; P2D receptor

Indexed keywords

2 METHYLTHIOADENOSINE TRIPHOSPHATE; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; CALCIUM ION; DIADENOSINE PENTAPHOSPHATE; DIADENOSINE TETRAPHOSPHATE; DIADENOSINE TRIPHOSPHATE; HYDROLASE; INOSINE; PURINE P2 RECEPTOR; SECRETORY LEUKOCYTE PROTEINASE INHIBITOR; SURAMIN;

ARTICLE; CALCIUM CELL LEVEL; CELL LINE; CELL SECRETION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYSTIC FIBROSIS; DESENSITIZATION; DRUG ANTAGONISM; DRUG HYDROLYSIS; HUMAN; HUMAN CELL; MUCUS GLAND; PRIORITY JOURNAL; SUBMUCOSA; TRACHEA; TRACHEA MUCUS;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; BINDING, COMPETITIVE; CALCIUM; CELLS, CULTURED; DINUCLEOSIDE PHOSPHATES; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; HYDROLYSIS; PROTEINASE INHIBITORY PROTEINS, SECRETORY; PROTEINS; RECEPTORS, PURINERGIC P2; SECRETORY LEUKOCYTE PEPTIDASE INHIBITOR; SURAMIN; THIONUCLEOTIDES; TRACHEA;

EID: 0032784352     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00621-4     Document Type: Article

References (28)

1. André P., Capo C., Benoliel A.M., Buferne M., Bongrand P. Analysis of the topological changes induced on cells exposed to adhesive or mechanical stimuli. Cell Biophys. 16:1990;13-34.
2. Basbaum C.B., Jany B., Finkbeiner W.E. The serous cell. Annu. Rev. Physiol. 52:1990;97-113.
3. 2+ stores mobilization by diadenosine tetraphosphate, AP4A, through a putative P2Y purinoceptor in adrenal chromaffin cells. Br. J. Pharmacol. 106:1992;833-837.
4. Communi D., Govaertes C., Parmentier M., Boeynaems J.M. Cloning of human purinergic P2Y receptor coupled to phospholipase C and adenylyl cyclase. J. Biol. Chem. 272:1997;31969-31973.
5. Engelhardt J.F., Yankaskas J.R., Ernst S.A., Yang Y.P., Marino C.R., Boucher R.C., Cohn J.A., Wilson J.M. Submucosal glands are the predominant site of CFTR expression in human bronchus. Nat. Genet. 2:1992;240-246.
6. Hilderman R.H., Martin M., Zimmerman J.K., Pivorum E.B. Identification of a unique membrane receptor for adenosine 5′,5‴-P1,P4-tetraphosphate. J. Biol. Chem. 266:1991;6915-6918.
7. Kisselev L.L., Justesen J., Wolfson A.D., Frolova L.Y. Diadenosine oligophosphates (APnA), a novel class of signalling molecules? FEBS Lett. 427:1998;157-163.
8. Knowles M.R., Clarke L.L., Boucher R.C. Activation by extracellular nucleotides of chloride secretion in the airway epithelia of patients with cystic fibrosis. N. Engl. J. Med. 325:1991;533-538.
9. Laubinger W., Reiser G. Evidence for a G protein-coupled diadenosine-5′,5‴- P1,P4-tetraphosphate (AP4A) receptor binding site in lung membranes from rat. Eur. J. Pharmacol. 366:1999;93-100.
10. Lazarowski E.R., Watt W.C., Stutts M.J., Boucher R.C., Harden T.K. Pharmacological selectivity of the cloned human P2U-purinoceptor: potent activation by diadenosine tetraphosphate. Br. J. Pharmacol. 116:1995;1619-1627.
11. Lemmens R., Vanduffel L., Teuchy H., Culic O. Regulation of proliferation of LLC-MK2 cells by nucleosides and nucleotides: the role of ecto-enzymes. Biochem. J. 316:1996;551-557.
12. Lo-Guidice J.M., Merten M., Lamblin G., Porchet N., Houvenaghel M.C, Figarella C., Roussel P., Périni J.M. Mucin-like glycoproteins secreted by an immortalized cell line derived from human tracheal gland cells. Biochem. J. 326:1997;431-437.
13. Mason S.J., Paradiso A.M., Boucher R.C. Regulation of transepithelial ion transport and intracellular calcium by extracellular ATP in human normal and cystic fibrosis airway epithelium. Br. J. Pharmacol. 103:1991;1649-1656.
14. Merten M.D., Tournier J.M., Meckler Y., Figarella C. Epinephrine promotes growth and differentiation of human tracheal gland cells in culture. Am. J. Respir. Cell Mol. Biol. 9:1993;172-178.
15. Merten M., Breittmayer J.P., Figarella C., Frelin C. ATP and UTP increase the secretion of the bronchial inhibitor by human tracheal gland cells in culture. Am. J. Physiol. 265:1993;L479-L484.
16. Merten M., Kammouni W., Renaud W., Birg F., Mattei M.G., Figarella C. A transformed human tracheal gland cells line, MM-39, that retains serous secretory functions. Am. J. Respir. Cell Mol. Biol. 15:1996;520-528.
17. Merten M., Saleh A., Kammouni W., Marchand S., Figarella C. Characterization of two distinct P2Y receptors in human tracheal gland cells. Eur. J. Biochem. 251:1998;19-24.
18. Miras-Portugal M.T., Gualix J., Pintor J. The neurotransmitter role of diadenosine polyphosphates. FEBS Lett. 430:1998;78-82.
19. Pintor J., Miras-Portugal M.T. P2 purinergic receptors for diadenosine polyphosphate in the nervous system. Gen. Pharmacol. 26:1995;229-235.
20. Pintor J., Miras-Portugal M.T. A novel receptor for diadenosine polyphosphate coupled to calcium increase in rat midbrain synaptosomes. Br. J. Pharmacol. 115:1995;895-902.
21. Pintor J., Diaz-Rey M.A., Miras-Portugal M.T. AP4A and ADPβS binding to P2-purinoceptors present on rat brain synaptic terminals. Br. J. Pharmacol. 108:1993;1094-1099.
22. + transients in guinea-pig brain via receptors distinct from those for ATP. J. Physiol. 504:1997;327-335.
23. Ralevic V., Burnstock G. Receptors for purines and pyrimidines. Pharmacol. Rev. 50:1998;413-492.
24. Riordan J.R., Rommens J.M., Kerem B.S., Alon N., Rozmahel R., Grzelczak Z., Zielenski J., Lok S., Plavsic N., Chou J.L., Drumm M.L., Iannuzzi M.C., Collins F.S., Tsui L.C. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science. 245:1989;1066-1073.
25. Sevigny J., Picher M., Grondin G., Beaudoin A.R. Purification and immunohistochemical localization of the ATP diphosphohydrolase in bovine lungs. Am. J. Physiol. 272:1997;L939-L950.
26. Schulze-Lohoff E., Zanner S., Ogilvie A., Sterzel R.B. Vasoactive diadenosine polyphosphates promote growth of cultured renal mesangial cells. Hypertension. 26:1995;899-904.
27. Tournier J.M., Jacquot J., Sadoul P., Bieth J.G. Non-competitive enzyme immunoassay for the measurement of bronchial inhibitor in biological fluids. Anal. Biochem. 131:1983;345-350.
28. Tournier J.M., Merten M.D., Meckler Y., Hinnrasky J., Fuchey C., Puchelle E. Culture and characterization of human tracheal gland cells. Am. Rev. Respir. Dis. 141:1990;1280-1288.