Electrophysiological properties of the human N-type Ca2+ channel: I. Channel gating in Ca2+ Ba2+ and Sr2+ containing solutions

Neuropharmacology

Volumn 36, Issue 7, 1997, Pages 895-915

  McNaughton, N C L ^a   Randall, A D ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

Calcium channel; Gating; Permeation; Toxin pharmacology

Indexed keywords

BARIUM ION; CALCIUM CHANNEL; CALCIUM ION; OMEGA CONOTOXIN GVIA; OMEGA CONOTOXIN MVIIC; STRONTIUM;

ARTICLE; CHANNEL GATING; CONTROLLED STUDY; HUMAN; HUMAN CELL; ION CURRENT; KIDNEY CELL; MEMBRANE CURRENT; PHENOTYPE; PRIORITY JOURNAL;

BARIUM; CALCIUM; CALCIUM CHANNELS; CELL LINE; HUMANS; ION CHANNEL GATING; KINETICS; STRONTIUM;

EID: 0030877819     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(97)00085-3     Document Type: Article

References (77)

1. Armstrong C. M. and Cota G. (1990) Modification of sodium channel gating by lanthanum: Some effects that cannot be explained by surface charge theory. Journal of General Physiology 96: 1129-1140.
2. Armstrong C. M. and Gilly W. F. (1992) Access resistance and space clamp problems associated with whole-cell patch clamping. Methods in Enzymology 207: 100-122.
3. Barry P. H. and Lynch J. W. (1991) Liquid junction potentials and small cell effects in patch clamp analysis. Journal of Membrane Biology 121: 101-117.
4. Bath C. P., Farrel L. N., Gilmore J., Ward M. A., Hicks C. A., O'Neill M. J. and Bleakman D. (1996) The effect of ifenprodil and eliprodil on voltage-dependent calcium channels and gerbil global cerebral ischemia. European Journal of Pharmacology 299: 103-112.
5. Berjukow S., Doring F., Froschmayr M., Grabner M., Glossman H. and Hering S. (1996) Endogenous calcium channels in human embryonic kidney (HEK293) cells. British Journal of Pharmacology 118: 748-754.
6. Bezprozvanny I., Scheller R. H. and Tsien R. W. (1995) Functional impact of syntaxin on gating of N-type and Q-type calcium channels. Nature 378: 623-626.
7. Bleakman D., Bowman D., Bath C. P., Brust P. F., Johnson E. C., Deal C. R., Miller R. J., Ellis S. B., Harpold M. M. and Hans M. (1995) Characteristics of a human N-type calcium channel expressed in HEK293 cells. Neuropharmacology 34: 753-765.
8. 2+ channel. Society for Neuroscience Abstracts 21: 514.
9. Boland L. M., Morrill J. A. and Bean B. P. (1994) Omega-Conotoxin block of N-type calcium channels in frog and rat sympathetic neurons. Journal of Neuroscience 14: 5011-5027.
10. Borst J. G. G., Helmchen F. and Sakmann B. (1995) Pre- and postsynaptic whole-cell recordings in the medial nucleus of the trapeziod body of the rat. Journal of Physiology 489: 825-840.
11. Brown A. M., Schwindt P. C. and Crill W. E. (1993) Voltage dependence and activation kinetics of pharmacologically defined components of the high-threshold calcium current in rat neocortical neurons. Journal of Neurophysiology 70: 1530-1543.
12. Byerly L., Chase P. B. and Stimers J. R. (1985) Permeation and interaction of divalent cations in calcium channels of snail neurons. Journal of General Physiology 85: 491-518.
13. Carbone E. and Swandulla D. (1989) Neuronal calcium channels: kinetics, blockade and modulation. Progress in Biophysics and Molecular Biology 54: 31-58.
14. Cox D. H. and Dunlap K. (1994) Inactivation of N-type calcium current in chick sensory neurons: calcium and voltage dependence. Journal of General Physiology 104: 311-336.
15. 2+ channels in mammalian central neurons. Trends in Neuroscience 18: 89-98.
16. Eckert R. and Chad J. E. (1984) Inactivation of Ca channels. Progress in Biophysics and Molecular Biology 44: 215-267.
17. Ellinor P. T., Zhang J. F., Home W. A. and Tsien R. W. (1994) Structural determinants of the blockade of N-type calcium channels by a peptide neurotoxin. Nature 372: 272-275.
18. Fedulova S. A., Kostyuk P. G. and Veselovsky N. S. (1985) Two types of calcium channels in the somatic membrane of new-born rat dorsal root ganglion neurones. Journal of Physiology (London) 359: 431-446.
19. Fox A. P., Nowycky M. C. and Tsien R. W. (1987) Kinetic and pharmacological properties distinguishing three types of calcium currents in chick sensory neurones. Journal of Physiology (London) 394: 149-172.
20. Fujita Y., Mynleiff M., Dirksen R. T., Kim M., Niidome T., Nakai J., Friedreich T., Iwabe N., Miyata T., Furuichi T., Furutama D., Mikoshiba K., Mori Y. and Beam K. G. (1993) Primary structure and functional expression of the ω-conotoxin-sensitive N-type calcium channel from rabbit brain. Neuron 10: 585-598.
21. Ganitkevich V., Shuba M. F. and Smirnov S. V. (1988) Saturation of calcium channels in single isolated smooth muscle cells of guinea-pig taenia caeci. Journal of Physiology (London) 399: 419-436.
22. Gilly W. F. and Armstrong C. M. (1982) Slowing of the sodium channel openning kinetics in squid axon by extracellular zinc. Journal of General Physiology 79: 935-964.
23. Hess P., Lansman J. B. and Tsien R. W. (1984) Different modes of Ca channel gating behaviour favoured by dihydropyridine Ca agonists and antagonists. Nature 311: 538-544.
24. Hess P. and Tsien R. W. (1984) Mechanism of ion permeation through calcium channels. Nature 309: 453-456.
25. Hille, B. (1992) Ionic channels of excitable membranes. Sinauer, Sunderland.
26. Hille B. (1994) Modulation of ion-channel function by G-protein-coupled receptors. Trends in Neuro 17: 531-535.
27. 2+ channels. Neuron 9: 69-77.
28. 2+ channels in evoked release of norepinephrine from sympathetic neurons. Science 239: 57-61.
29. Hodgkin A. L. and Huxley A. F. (1952) A quantitative description of membrane current and its application to conduction and excitation in nerve. Journal of Physiology (London) 117: 500-544.
30. Jones M. V. and Westbrook G. L. (1996) The impact of receptor desensitization on fast synaptic transmission. Trends in Neuroscience 19: 96-101.
31. Jones S. W. and Marks T. N. (1989) Calcium currents in bullfrog sympathetic neurons. I. Activation kinetics and pharmacology. Journal of General Physiology 94: 151-167.
32. Kasai H. and Aosaki T. (1988) Divalent cation dependent inactivation of the high-voltage-activated Ca-channel current in chick sensory neurons. Pflugers Archives 411: 695-697.
33. Kasai H. and Neher E. (1992) Dihydropyridine-sensitive and omega-conotoxin-sensitive calcium channels in a mammalian neuroblastoma-glioma cell line. Journal of Physiology (London) 448: 161-188.
34. Keynes R. D. (1994) The kinetics of voltage-gated channels. Quarterly Reviews of Biophysics 27: 339-434.
35. Klockner U. and Isenberg G. (1994) Calcium channel current of vascular smooth muscle cells: extracellular protons modulate gating and single channel conductance. Journal of General Physiology 103: 665-678.
36. Kostyuk P. G., Mironov S. L., Doroshenko P. A. and Ponomarev V. N. (1982) Surface charges on the outer side of mollusc neuron membrane. Journal of Membrane Biology 70: 171-179.
37. Kuo C. C. and Bean B. P. (1993) G-protein modulation of ion permeation through N-type calcium channels. Nature 365: 258-262.
38. Matteson D. R. and Armstrong C. M. (1986) Properties of two types of calcium channels in clonal pituitary cells. Journal of General Physiology 87: 161-182.
39. McCobb D. P. and Beam K. G. (1991) Action potential waveform voltage-clamp commands reveal striking differences in calcium entry via low and high voltage-activated calcium channels. Neuron 7: 119-127.
40. McDonough S. I., Swartz K. J., Mintz I. M., Boland L. M. and Bean B. P. (1996) Inhibition of Calcium channels in rat central and peripheral neurons by ω-Conotoxin MVIIC. Journal of Neuroscience 16: 2612-2623.
41. 2+ channel. Journal of Physiology (in press).
42. 2+-containing extracellular solutions. Journal of Physiology 495: 77P.
43. Miljanich G. P. and Ramachandran J. (1995) Antagonists of neuronal calcium channels: structure, function, and therapeutic implications. Annual Review of Pharmacology and Toxicology 35: 707-734.
44. Mintz I. M., Sabatini B. L. and Regehr W. G. (1995) Calcium control of transmitter release at a cerebellar synapse. Neuron 15: 675-688.
45. Narahashi T., Tsunoo A. and Yoshii M. (1987) Characterization of two types of calcium channels in mouse neuroblastoma cells. Journal of Physiology (London) 383: 231-249.
46. Nobile M., Carbone E., Lux H. D. and Zucker H. (1990) Temperature sensitivity of Ca currents in chick sensory neurones. Pflugers Archives 415: 658-663.
47. Ohmori H. and Yoshii M. (1977) Surface potential reflected in both gating and permeation mechanisms of sodium and calcium channels of the tunicate egg cell membrane. Journal of Physiology (London) 267: 429-463.
48. Olivera B. M., Miljanich G. P., Ramachandran J. and Adams M. E. (1994) Calcium channel diversity and neurotransmitter release: the omega-conotoxins and omega-agatoxins. Annual Review of Biochemistry 63: 823-867.
49. Piccolino M. and Pignatelli A. (1996) Calcium-independent synaptic transmission artifact or fact. Trends in Neuroscience 19: 120-125.
50. + as permeant ions. Journal of General Physiology 94: 1-21.
51. Plummer M. R. and Hess P. (1991) Reversible uncoupling of inactivation in N-type calcium channels. Nature 351: 657-659.
52. Prod'hom B., Pietrobon D. and Hess P. (1989) Interactions of protons with single open L-type calcium channels. Location of protonation site and dependence of proton-induced current fluctuations on concentration and species of permeant ion. Journal of General Physiology 94: 23-42.
53. Saimi Y. and Kung C. (1982) Are ions involved in the gating of calcium channels? Science 218: 153-156.
54. Sala F. (1991) Activation kinetics of calcium currents in bullfrog sympathetic neurones. Journal of Physiology (London) 437: 221-238.
55. Sather W. A., Yang J. and Tsien R. W. (1994) Structural basis of ion channel permeation and selectivity. Current Opinion in Neurobiology 4: 313-323.
56. Sayer R. J., Brown A. M., Schwindt P. C. and Crill W. E. (1993) Calcium currents in acutely isolated human neocortical neurons. Journal of Neurophysiology 69: 1596-1606.
57. 2+ channel alpha 1 subunit. Receptors and Channels 2: 255-270.
58. Schultz D., Mikala G., Yatani A., Engle D. B., Iles D. E., Segers B., Sinke R. J., Weghuis D. O., Klockner U. and Wakamori M. (1993) Cloning, chromosomal localization, and functional expression of the alpha 1 subunit of the L-type voltage-dependent calcium channel from normal human heart. Proceedings of the National Academy of Science U.S.A. A 90: 6228-6232.
59. 2+ currents elicited by action potential waveforms in acutely isolated adult rat dorsal root ganglion neurons. Journal of Neuroscience 12: 1789-1801.
60. Simard J. M., Song Y., Tewari K., Dunn S., Werrbach Perez K., Perez Polo J. R. and Eisenberg H. M. (1993) Ionic channel currents in cultured neurons from human cortex. Journal of Neuroscience Research 34: 170-178.
61. Smith P. A., Aschroft F. M. and Fewtrell C. M. (1993) Permeation and gating properties of the L-type calcium channel in mouse pancreatic beta cells. Journal of General Physiology 101: 767-797.
62. 2+ channel alpha 1-subunit. Neuropharmacology 32: 1103-1116.
63. Swandulla D. and Armstrong C. M. (1988) Fast deactivating calcium channels in chick sensory neurons. Journal of General Physiology 92: 197-218.
64. Takahashi T., Forsythe I. D., Tsujimoto T., Barnes-Davies M. and Onodera K. (1996) Presynaptic calcium current modulation by a metabotropic glutamate receptor. Science 274: 594-597.
65. Takahashi T. and Momiyama A. (1993) Different types of calcium channels mediate central synaptic transmission. Nature 366: 156-158.
66. Tsien R. W., Hess P., McCleskey E. W. and Rosenberg R. L. (1987) Calcium channels: mechanisms of selectivity, permeation, and block. Annual Review of Biophysics and Biophysical Chemistry 16: 265-290.
67. Turner T. J., Lampe R. A. and Dunlap K. (1995) Characterization of presynaptic calcium channels with omega-conotoxin MVIIC and omega-grammotoxin SIA: role for a resistant calcium channel type in neurosecretion. Molecular Pharmacology 47: 348-353.
68. 2+ channels in supporting hippocampal synaptic transmission. Science 264: 107-111.
69. 2+ channels in rat hippocampus. Journal of Neuroscience 16: 2226-2237.
70. Williams M. E., Brust P. F., Feldman D. H., Patthi S., Simerson S., Maroufi A., McCue A. F., Velicelebi G., Ellis S. B. and Harpold M. M. (1992a) Structure and functional expression of an omega-conotoxin-sensitive human N-type calcium channel. Science 257: 389-395.
71. Williams M. E., Feldman D. H., McCue A. F., Brenner R., Velicelebi G., Ellis S. B. and Harpold M. M. (1992b) Structure and functional expression of alpha 1, alpha 2, and beta subunits of a novel human neuronal calcium channel subtype. Neuron 8: 71-84.
72. Williams M. E., Marubio L. M., Deal C. R., Hans M., Brust P. F., Philipson L. H., Miller R. J., Johnson E. C., Harpold M. M. and Ellis S. B. (1994) Structure and functional characterization of neuronal alpha 1E calcium channel subtypes. Journal of Biological Chemistry 269: 22347-22357.
73. Wu L. G. and Saggau P. (1995) Block of multiple presynaptic calcium channel types by omega-conotoxin-MVIIC at hippocampal CA3 to CA1 synapses. Journal of Neurophysiology 73: 1965-1972.
74. Zamponi G. W. and Snutch T. P. (1996) Evidence for a specific site for modulation of calcium channel activation by external calcium ions. Pflugers Archives 431: 470-472.
75. Zhang J. F., Ellinor P. T., Aldrich R. W. and Tsien R. W. (1994) Molecular determinants of voltage-dependent inactivation in calcium channels. Nature 372: 97-100.
76. Zhou W. and Jones S. W. (1995) Surface charge and calcium channel saturation in bullfrog sympathetic neurons. Journal of General Physiology 105: 441-462.
77. 2+)-channel currents by protein kinase C in adult rat sympathetic neurons. Journal of Neurophysiology 72: 1549-1560