-
1
-
-
0023789150
-
Chromosome breakage and recombination at fragile sites
-
Glover T.W., and Stein C.K. Chromosome breakage and recombination at fragile sites. Am. J. Hum. Genet. 43 (1988) 265-273
-
(1988)
Am. J. Hum. Genet.
, vol.43
, pp. 265-273
-
-
Glover, T.W.1
Stein, C.K.2
-
2
-
-
0023910775
-
Translocation t(3;8)(p14.2;q24.1) in renal cell carcinoma affects expression of the common fragile site at 3p14(FRA3B) in lymphocytes
-
Glover T.W., Coyle-Morris J.F., Li F.P., Brown R.S., Berger C.S., Gemmill R.M., and Hecht F. Translocation t(3;8)(p14.2;q24.1) in renal cell carcinoma affects expression of the common fragile site at 3p14(FRA3B) in lymphocytes. Cancer Genet. Cytogenet. 31 (1988) 69-73
-
(1988)
Cancer Genet. Cytogenet.
, vol.31
, pp. 69-73
-
-
Glover, T.W.1
Coyle-Morris, J.F.2
Li, F.P.3
Brown, R.S.4
Berger, C.S.5
Gemmill, R.M.6
Hecht, F.7
-
3
-
-
0026017993
-
Preferential integration of marker DNA into the chromosomal fragile site at 3p14: an approach to cloning fragile sites
-
Rassool F.V., McKeithan T.W., Neilly M.E., van Melle E., Espinosa III R., and Le Beau M.M. Preferential integration of marker DNA into the chromosomal fragile site at 3p14: an approach to cloning fragile sites. Proc. Natl. Acad. Sci. U. S. A. 88 (1991) 6657-6661
-
(1991)
Proc. Natl. Acad. Sci. U. S. A.
, vol.88
, pp. 6657-6661
-
-
Rassool, F.V.1
McKeithan, T.W.2
Neilly, M.E.3
van Melle, E.4
Espinosa III, R.5
Le Beau, M.M.6
-
4
-
-
13344279424
-
The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers
-
Ohta M., Inoue H., Cotticelli M.G., Kastury K., Baffa R., Palazzo J., Siprashvili Z., Mori M., McCue P., Druck T., Croce C.M., and Huebner K. The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers. Cell 84 (1996) 587-597
-
(1996)
Cell
, vol.84
, pp. 587-597
-
-
Ohta, M.1
Inoue, H.2
Cotticelli, M.G.3
Kastury, K.4
Baffa, R.5
Palazzo, J.6
Siprashvili, Z.7
Mori, M.8
McCue, P.9
Druck, T.10
Croce, C.M.11
Huebner, K.12
-
5
-
-
0036900616
-
FHIT: from gene discovery to cancer treatment and prevention
-
Pekarsky Y., Zanesi N., Palamarchuk A., Huebner K., and Croce C.M. FHIT: from gene discovery to cancer treatment and prevention. Lancet Oncol. 3 (2002) 748-754
-
(2002)
Lancet Oncol.
, vol.3
, pp. 748-754
-
-
Pekarsky, Y.1
Zanesi, N.2
Palamarchuk, A.3
Huebner, K.4
Croce, C.M.5
-
6
-
-
0038793721
-
Cancer and the FRA3B/FHIT fragile locus: it's a HIT
-
Huebner K., and Croce C.M. Cancer and the FRA3B/FHIT fragile locus: it's a HIT. Br. J. Cancer 88 (2003) 1501-1506
-
(2003)
Br. J. Cancer
, vol.88
, pp. 1501-1506
-
-
Huebner, K.1
Croce, C.M.2
-
7
-
-
0030974681
-
Association between cigarette smoking and FHIT gene alterations in lung cancer
-
Sozzi G., Sard L., De Gregorio L., Marchetti A., Musso K., Buttitta F., Tornielli S., Pellegrini S., Veronese M.L., Manenti G., Incarbone M., Chella A., Angeletti C.A., Pastorino U., Huebner K., Bevilaqua G., Pilotti S., Croce C.M., and Pierotti M.A. Association between cigarette smoking and FHIT gene alterations in lung cancer. Cancer Res. 57 (1997) 2121-2123
-
(1997)
Cancer Res.
, vol.57
, pp. 2121-2123
-
-
Sozzi, G.1
Sard, L.2
De Gregorio, L.3
Marchetti, A.4
Musso, K.5
Buttitta, F.6
Tornielli, S.7
Pellegrini, S.8
Veronese, M.L.9
Manenti, G.10
Incarbone, M.11
Chella, A.12
Angeletti, C.A.13
Pastorino, U.14
Huebner, K.15
Bevilaqua, G.16
Pilotti, S.17
Croce, C.M.18
Pierotti, M.A.19
-
8
-
-
0038797808
-
Immunohistochemical expression of FHIT gene product in inflammatory bowel disease: significance and correlation with clinicopathological data
-
Skopelitou A.S., Katsanos K.H., Michail M., Mitselou A., and Tsianos E.V. Immunohistochemical expression of FHIT gene product in inflammatory bowel disease: significance and correlation with clinicopathological data. Eur. J. Gastroenterol. Hepatol. 15 (2003) 665-673
-
(2003)
Eur. J. Gastroenterol. Hepatol.
, vol.15
, pp. 665-673
-
-
Skopelitou, A.S.1
Katsanos, K.H.2
Michail, M.3
Mitselou, A.4
Tsianos, E.V.5
-
9
-
-
0038402634
-
Immunohistochemical expression of Fhit protein in Helicobacter pylori related chronic gastritis, gastric precancerous lesions and gastric carcinoma: correlation with conventional clinicopathologic parameters
-
Skopelitou A.S., Mitselou A., Katsanos K.H., Alexopoulou V., and Tsianos E.V. Immunohistochemical expression of Fhit protein in Helicobacter pylori related chronic gastritis, gastric precancerous lesions and gastric carcinoma: correlation with conventional clinicopathologic parameters. Eur. J. Gastroenterol. Hepatol. 15 (2003) 515-523
-
(2003)
Eur. J. Gastroenterol. Hepatol.
, vol.15
, pp. 515-523
-
-
Skopelitou, A.S.1
Mitselou, A.2
Katsanos, K.H.3
Alexopoulou, V.4
Tsianos, E.V.5
-
10
-
-
0034638604
-
Frequent altered expression of fragile histidine triad protein in human colorectal adenomas
-
Morikawa H., Nakagawa Y., Hashimoto K., Niki M., Egashira Y., Hirata I., Katsu K., and Akao Y. Frequent altered expression of fragile histidine triad protein in human colorectal adenomas. Biochem. Biophys. Res. Commun. 278 (2000) 205-210
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.278
, pp. 205-210
-
-
Morikawa, H.1
Nakagawa, Y.2
Hashimoto, K.3
Niki, M.4
Egashira, Y.5
Hirata, I.6
Katsu, K.7
Akao, Y.8
-
11
-
-
0037452579
-
Designed FHIT alleles establish that Fhit-induced apoptosis in cancer cells is limited by substrate binding
-
Trapasso F., Krakowiak A., Cesari R., Arkles J., Yendamuri S., Ishii H., Vecchione A., Kuroki T., Bieganowski P., Pace H.C., Huebner K., Croce C.M., and Brenner C. Designed FHIT alleles establish that Fhit-induced apoptosis in cancer cells is limited by substrate binding. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 1592-1597
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 1592-1597
-
-
Trapasso, F.1
Krakowiak, A.2
Cesari, R.3
Arkles, J.4
Yendamuri, S.5
Ishii, H.6
Vecchione, A.7
Kuroki, T.8
Bieganowski, P.9
Pace, H.C.10
Huebner, K.11
Croce, C.M.12
Brenner, C.13
-
12
-
-
0037444152
-
Restoration of fragile histidine triad (FHIT) expression induces apoptosis and suppresses tumorigenicity in breast cancer cell lines
-
Sevignani C., Calin G.A., Cesari R., Sarti M., Ishii H., Yendamuri S., Vecchione A., Trapasso F., and Croce C.M. Restoration of fragile histidine triad (FHIT) expression induces apoptosis and suppresses tumorigenicity in breast cancer cell lines. Cancer Res. 63 (2003) 1183-1187
-
(2003)
Cancer Res.
, vol.63
, pp. 1183-1187
-
-
Sevignani, C.1
Calin, G.A.2
Cesari, R.3
Sarti, M.4
Ishii, H.5
Yendamuri, S.6
Vecchione, A.7
Trapasso, F.8
Croce, C.M.9
-
13
-
-
0022269978
-
5′,5‴-P1, P4 diadenosine tetraphosphate (Ap4A): a putative initiator of DNA replication
-
Baril E.F., Coughlin S.A., and Zamecnik P.C. 5′,5‴-P1, P4 diadenosine tetraphosphate (Ap4A): a putative initiator of DNA replication. Cancer Invest. 3 (1985) 465-471
-
(1985)
Cancer Invest.
, vol.3
, pp. 465-471
-
-
Baril, E.F.1
Coughlin, S.A.2
Zamecnik, P.C.3
-
14
-
-
17944363271
-
Enhancement of oxidative damage to cultured cells and Caenorhabditis elegans by mitochondrial electron transport inhibitors
-
Ishiguro H., Yasuda K., Ishii N., Ihara K., Ohkubo T., Hiyoshi M., Ono K., Senoo-Matsuda N., Shinohara O., Yosshii F., Murakami M., Hartman P.S., and Tsuda M. Enhancement of oxidative damage to cultured cells and Caenorhabditis elegans by mitochondrial electron transport inhibitors. IUBMB Life 51 (2001) 263-268
-
(2001)
IUBMB Life
, vol.51
, pp. 263-268
-
-
Ishiguro, H.1
Yasuda, K.2
Ishii, N.3
Ihara, K.4
Ohkubo, T.5
Hiyoshi, M.6
Ono, K.7
Senoo-Matsuda, N.8
Shinohara, O.9
Yosshii, F.10
Murakami, M.11
Hartman, P.S.12
Tsuda, M.13
-
15
-
-
0036169830
-
Selective nitration of mitochondrial complex I by peroxynitrite: involvement in mitochondria dysfunction and cell death of dopaminergic SH-SY5Y cells
-
Yamamoto T., Maruyama W., Kato Y., Yi H., Shamoto-Nagai M., Tanaka M., Sato Y., and Naoi M. Selective nitration of mitochondrial complex I by peroxynitrite: involvement in mitochondria dysfunction and cell death of dopaminergic SH-SY5Y cells. J. Neural. Transm. 109 (2002) 1-13
-
(2002)
J. Neural. Transm.
, vol.109
, pp. 1-13
-
-
Yamamoto, T.1
Maruyama, W.2
Kato, Y.3
Yi, H.4
Shamoto-Nagai, M.5
Tanaka, M.6
Sato, Y.7
Naoi, M.8
-
16
-
-
0034946830
-
Effect of proteasome inhibition on cellular oxidative damage, antioxidant defences and nitric oxide production
-
Lee M.H., Hyun D.H., Jenner P., and Halliwell B. Effect of proteasome inhibition on cellular oxidative damage, antioxidant defences and nitric oxide production. J. Neurochem. 78 (2001) 32-41
-
(2001)
J. Neurochem.
, vol.78
, pp. 32-41
-
-
Lee, M.H.1
Hyun, D.H.2
Jenner, P.3
Halliwell, B.4
-
17
-
-
0032032469
-
Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa B
-
Wahl C., Liptay S., Adler G., and Schmid R.M. Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa B. J. Clin. Invest. 101 (1998) 1163-1174
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 1163-1174
-
-
Wahl, C.1
Liptay, S.2
Adler, G.3
Schmid, R.M.4
-
18
-
-
0033571108
-
The antiinflammatory sesquiterpene lactone parthenolide inhibits NF-κB by targeting the IκB kinase complex
-
Hehner S.P., Hofmann T.G., Droge W., and Schmitz M.L. The antiinflammatory sesquiterpene lactone parthenolide inhibits NF-κB by targeting the IκB kinase complex. J. Immunol. 163 (1999) 5617-5623
-
(1999)
J. Immunol.
, vol.163
, pp. 5617-5623
-
-
Hehner, S.P.1
Hofmann, T.G.2
Droge, W.3
Schmitz, M.L.4
-
19
-
-
15744396281
-
A potent apoptosis-inducing activity of a sesquiterpene lactone, arucanolide, in HL60 cells: a crucial role of apoptosis-inducing factor
-
Nakagawa Y., Iinuma M., Matsuura N., Yi K., Naoi M., Nakayama T., Nozawa Y., and Akao Y. A potent apoptosis-inducing activity of a sesquiterpene lactone, arucanolide, in HL60 cells: a crucial role of apoptosis-inducing factor. J. Pharmacol. Sci. 97 (2005) 242-252
-
(2005)
J. Pharmacol. Sci.
, vol.97
, pp. 242-252
-
-
Nakagawa, Y.1
Iinuma, M.2
Matsuura, N.3
Yi, K.4
Naoi, M.5
Nakayama, T.6
Nozawa, Y.7
Akao, Y.8
-
20
-
-
0037192453
-
Arsenic trioxide-induced apoptosis through oxidative stress in cells of colon cancer cell lines
-
Nakagawa Y., Akao Y., Morikawa H., Hirata I., Katsu K., Naoe T., Ohishi N., and Yagi K. Arsenic trioxide-induced apoptosis through oxidative stress in cells of colon cancer cell lines. Life Sci. 70 (2002) 2253-2269
-
(2002)
Life Sci.
, vol.70
, pp. 2253-2269
-
-
Nakagawa, Y.1
Akao, Y.2
Morikawa, H.3
Hirata, I.4
Katsu, K.5
Naoe, T.6
Ohishi, N.7
Yagi, K.8
-
21
-
-
0032537499
-
Growth inhibition by overexpression of human DEAD box protein rck/p54 in cells of a guinea pig cell line
-
Akao Y., Mizoguchi H., Ohishi N., and Yagi K. Growth inhibition by overexpression of human DEAD box protein rck/p54 in cells of a guinea pig cell line. FEBS Lett. 429 (1998) 279-283
-
(1998)
FEBS Lett.
, vol.429
, pp. 279-283
-
-
Akao, Y.1
Mizoguchi, H.2
Ohishi, N.3
Yagi, K.4
-
22
-
-
11544354950
-
Genetic, biochemical, and crystallographic characterization of Fhit-substrate complexes as the active signaling form of Fhit
-
Pace H.C., Garrison P.N., Robinson A.K., Barnes L.D., Draganescu A., Rosler A., Blackburn G.M., Siprashvili Z., Croce C.M., Huebner K., and Brenner C. Genetic, biochemical, and crystallographic characterization of Fhit-substrate complexes as the active signaling form of Fhit. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 5484-5489
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 5484-5489
-
-
Pace, H.C.1
Garrison, P.N.2
Robinson, A.K.3
Barnes, L.D.4
Draganescu, A.5
Rosler, A.6
Blackburn, G.M.7
Siprashvili, Z.8
Croce, C.M.9
Huebner, K.10
Brenner, C.11
-
23
-
-
0033971901
-
bcl-2 family: life-or-death switch
-
Tsujimoto Y., and Shimizu S. bcl-2 family: life-or-death switch. FEBS Lett. 466 (2000) 6-10
-
(2000)
FEBS Lett.
, vol.466
, pp. 6-10
-
-
Tsujimoto, Y.1
Shimizu, S.2
-
24
-
-
0028880006
-
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
-
Xia Z., Dickens M., Raingeaud J., Davis R.J., and Greenberg M.E. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270 (1995) 1326-1331
-
(1995)
Science
, vol.270
, pp. 1326-1331
-
-
Xia, Z.1
Dickens, M.2
Raingeaud, J.3
Davis, R.J.4
Greenberg, M.E.5
-
25
-
-
0032493729
-
Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway
-
Pap M., and Cooper G.M. Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway. J. Biol. Chem. 273 (1998) 19929-19932
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 19929-19932
-
-
Pap, M.1
Cooper, G.M.2
-
26
-
-
0034708775
-
Pervanadate-induced nuclear factor-κB activation requires tyrosine phosphorylation and degradation of IκBα
-
Mukhopadhyay A., Manna S.K., and Aggarwal B.B. Pervanadate-induced nuclear factor-κB activation requires tyrosine phosphorylation and degradation of IκBα. J. Biol. Chem. 275 (2000) 8549-8555
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 8549-8555
-
-
Mukhopadhyay, A.1
Manna, S.K.2
Aggarwal, B.B.3
-
27
-
-
22144432216
-
Mitochondrial reactive oxygen species regulate the temporal activation of nuclear factor κB to modulate tumour necrosis factor-induced apoptosis: evidence from mitochondria-targeted antioxidants
-
Hughes G., Murphy M.P., and Ledgerwood E.C. Mitochondrial reactive oxygen species regulate the temporal activation of nuclear factor κB to modulate tumour necrosis factor-induced apoptosis: evidence from mitochondria-targeted antioxidants. Biochem. J. 389 (2005) 83-89
-
(2005)
Biochem. J.
, vol.389
, pp. 83-89
-
-
Hughes, G.1
Murphy, M.P.2
Ledgerwood, E.C.3
-
29
-
-
0034193257
-
The Fhit tumor suppressor protein regulates the intracellular concentration of diadenosine triphosphate but not diadenosine tetraphosphate
-
Murphy G.A., Halliday D., and McLennan A.G. The Fhit tumor suppressor protein regulates the intracellular concentration of diadenosine triphosphate but not diadenosine tetraphosphate. Cancer Res. 60 (2000) 2342-2344
-
(2000)
Cancer Res.
, vol.60
, pp. 2342-2344
-
-
Murphy, G.A.1
Halliday, D.2
McLennan, A.G.3
-
30
-
-
2542449068
-
Enhanced chemosensitivity to irinotecan by RNA interference-mediated down-regulation of the nuclear factor-kappaB p65 subunit
-
Guo J., Verma U.N., Gaynor R.B., Frenkel E.P., and Becerra C.R. Enhanced chemosensitivity to irinotecan by RNA interference-mediated down-regulation of the nuclear factor-kappaB p65 subunit. Clin. Cancer Res. 10 (2004) 3333-3341
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 3333-3341
-
-
Guo, J.1
Verma, U.N.2
Gaynor, R.B.3
Frenkel, E.P.4
Becerra, C.R.5
-
31
-
-
0037332580
-
Tetrameric oligomerization of IκB kinaseγ (IKKγ) is obligatory for IKK complex activity and NF-κB activation
-
Tegethoff S., Behlke J., and Scheidereit C. Tetrameric oligomerization of IκB kinaseγ (IKKγ) is obligatory for IKK complex activity and NF-κB activation. Mol. Cell. Biol. 23 (2003) 2029-2041
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 2029-2041
-
-
Tegethoff, S.1
Behlke, J.2
Scheidereit, C.3
-
32
-
-
0029146930
-
Signal-induced site-specific phosphorylation targets IκBα to the ubiquitin-proteasome pathway
-
Chen Z., Hagler J., Palombella V.J., Melandri F., Scherer D., Ballard D., and Maniatis T. Signal-induced site-specific phosphorylation targets IκBα to the ubiquitin-proteasome pathway. Genes. Dev. 9 (1995) 1586-1597
-
(1995)
Genes. Dev.
, vol.9
, pp. 1586-1597
-
-
Chen, Z.1
Hagler, J.2
Palombella, V.J.3
Melandri, F.4
Scherer, D.5
Ballard, D.6
Maniatis, T.7
-
33
-
-
0020645358
-
P1,P4-Di(adenosine-5′)tetraphosphate inhibits phosphorylation of immunoglobulin G by Rous sarcoma virus pp60src
-
Maness P.F., Perry M.E., and Levy B.T. P1,P4-Di(adenosine-5′)tetraphosphate inhibits phosphorylation of immunoglobulin G by Rous sarcoma virus pp60src. J. Biol. Chem. 258 (1983) 4055-4058
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 4055-4058
-
-
Maness, P.F.1
Perry, M.E.2
Levy, B.T.3
-
34
-
-
0027723476
-
The major acidic fibroblast growth factor (aFGF)-stimulated phosphoprotein from bovine liver plasma membranes has aFGF-stimulated kinase, autoadenylylation, and alkaline nucleotide phosphodiesterase activities
-
Oda Y., Kuo M.D., Huang S.S., and Huang J.S. The major acidic fibroblast growth factor (aFGF)-stimulated phosphoprotein from bovine liver plasma membranes has aFGF-stimulated kinase, autoadenylylation, and alkaline nucleotide phosphodiesterase activities. J. Biol. Chem. 268 (1993) 27318-27326
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 27318-27326
-
-
Oda, Y.1
Kuo, M.D.2
Huang, S.S.3
Huang, J.S.4
-
35
-
-
0034532979
-
Association of FHIT (fragile histidine triad), a candidate tumour suppressor gene, with the ubiquitin-conjugating enzyme hUBC9
-
Shi Y., Zou M., Farid N.R., and Paterson M.C. Association of FHIT (fragile histidine triad), a candidate tumour suppressor gene, with the ubiquitin-conjugating enzyme hUBC9. Biochem. J. 352 (2000) 443-448
-
(2000)
Biochem. J.
, vol.352
, pp. 443-448
-
-
Shi, Y.1
Zou, M.2
Farid, N.R.3
Paterson, M.C.4
-
36
-
-
3042833259
-
Ubc9-induced inhibition of diadenosine triphosphate hydrolase activity of the putative tumor suppressor protein Fhit
-
Golebiowski F., Szulc A., Szutowicz A., and Pawelczyk T. Ubc9-induced inhibition of diadenosine triphosphate hydrolase activity of the putative tumor suppressor protein Fhit. Arch. Biochem. Biophys. 428 (2004) 160-164
-
(2004)
Arch. Biochem. Biophys.
, vol.428
, pp. 160-164
-
-
Golebiowski, F.1
Szulc, A.2
Szutowicz, A.3
Pawelczyk, T.4
|