Bacterial genotoxin triggers FEN1-dependent RhoA activation, cytoskeleton remodeling and cell survival

Journal of Cell Science

Volumn 124, Issue 16, 2011, Pages 2735-2742

  Guerra, Lina ^a   Guidi, Riccardo ^a   Slot, Ilse ^a   Callegari, Simone ^a   Sompallae, Ramakrishna ^a   Pickett, Carol L ^b   Åström, Stefan ^c   Eisele, Frederik ^d   Wolf, Dieter ^d   Sjögren, Camilla ^a   Masucci, Maria G ^a   Frisan, Teresa ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

^c STOCKHOLM UNIVERSITY   (Sweden)

^d UNIVERSITY OF STUTTGART   (Germany)

Author keywords

Actin cytoskeleton; Cell survival; Cytolethal distending toxin; DNA damage; FEN1; RhoA; TSG101

Indexed keywords

ACTIN; CYTOLETHAL DISTENDING TOXIN; CYTOLETHAL DISTENDING TOXIN B; DNA; FEN1 PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; TUMOR SUSCEPTIBILITY GENE 101 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BIOINFORMATICS; CELL SURVIVAL; CONTROLLED STUDY; CYTOSKELETON; DELETION MUTANT; DNA DAMAGE; DNA REPAIR; EFFECTOR CELL; ENDOCYTOSIS; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION;

ACTINS; BACTERIAL TOXINS; CELL SURVIVAL; COMPUTATIONAL BIOLOGY; CYTOSKELETON; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; ENDOCYTOSIS; ENDOSOMAL SORTING COMPLEXES REQUIRED FOR TRANSPORT; FLAP ENDONUCLEASES; HELA CELLS; HUMANS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RHOA GTP-BINDING PROTEIN; SACCHAROMYCES CEREVISIAE; SEQUENCE DELETION; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSGENES;

BACTERIA (MICROORGANISMS); SACCHAROMYCES CEREVISIAE;

EID: 79961160914     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.085845     Document Type: Article

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