-
1
-
-
0036204179
-
Practice guidelines for sedation and analgesia by nonanesthesiologists
-
Apr
-
Practice guidelines for sedation and analgesia by nonanesthesiologists. Anesthesiology 2002 Apr; 96 (4): 1004-17.
-
(2002)
Anesthesiology
, vol.96
, Issue.4
, pp. 1004-1017
-
-
-
3
-
-
72249105873
-
Use of intravenous infusion sedation among mechanically ventilated patients in the United States
-
Dec 1
-
Wunsch H, Kahn JM, Kramer AA, et al. Use of intravenous infusion sedation among mechanically ventilated patients in the United States. Crit Care Med 2009Dec 1; 37 (12): 3031-9.
-
(2009)
Crit Care Med
, vol.37
, Issue.12
, pp. 3031-3039
-
-
Wunsch, H.1
Kahn, J.M.2
Kramer, A.A.3
-
4
-
-
33748086044
-
Pharmacokinetic and pharmacodynamic characteristics of medications used for moderate sedation
-
Gan TG. Pharmacokinetic and pharmacodynamic characteristics of medications used for moderate sedation. Clin Pharmacokinet 2006; 45 (9): 855-69.
-
(2006)
Clin Pharmacokinet
, vol.45
, Issue.9
, pp. 855-869
-
-
Gan, T.G.1
-
5
-
-
59649118745
-
A new era for sedation in ICU patients
-
Feb
-
Wunsch H, Kress JP. A new era for sedation in ICU patients. JAMA 2009 Feb; 301 (5): 542-4.
-
(2009)
JAMA
, vol.301
, Issue.5
, pp. 542-544
-
-
Wunsch, H.1
Kress, J.P.2
-
6
-
-
0034106127
-
Dexmedetomidine
-
Bhana N, Goa KL, McClellan KJ. Dexmedetomidine. Drugs 2000 Feb; 59 (2): 263-8; discussion 269-70. (Pubitemid 30168513)
-
(2000)
Drugs
, vol.59
, Issue.2
, pp. 263-268
-
-
Bhana, N.1
Goa, K.L.2
McClellan, K.J.3
-
8
-
-
77954459092
-
Use of dexmedetomidine as a sedative and analgesic agent in critically ill adult patients: A metaanalysis
-
Jun
-
Tan JA, Ho KM. Use of dexmedetomidine as a sedative and analgesic agent in critically ill adult patients: a metaanalysis. Intensive Care Med 2010 Jun; 36 (6): 926-39.
-
(2010)
Intensive Care Med
, vol.36
, Issue.6
, pp. 926-939
-
-
Tan, J.A.1
Ho, K.M.2
-
9
-
-
67650519450
-
Alpha 2 adrenoceptor agonist-dexmedetomidine role in anaesthesia and intensive care: A clinical review
-
Murthy TVSP, Singh R. Alpha 2 adrenoceptor agonist-dexmedetomidine role in anaesthesia and intensive care: a clinical review. J Anaesthesiol Clin Pharmacol 2009; 25 (3): 267-72.
-
(2009)
J Anaesthesiol Clin Pharmacol
, vol.25
, Issue.3
, pp. 267-272
-
-
Murthy, T.V.S.P.1
Singh, R.2
-
10
-
-
53749086162
-
Dexmedetomidine: A useful adjunct to consider in some high-risk situations
-
Oct
-
Haselman MA. Dexmedetomidine: a useful adjunct to consider in some high-risk situations. AANA J 2008 Oct; 76 (5): 335-9.
-
(2008)
AANA J
, vol.76
, Issue.5
, pp. 335-339
-
-
Ma, H.1
-
11
-
-
67649354229
-
Pharmacology of sedativeanalgesic agents: Dexmedetomidine, remifentanil, ketamine, volatile anesthetics, and the role of peripheral mu antagonists
-
Jul
-
Panzer O, Moitra V, Sladen RN. Pharmacology of sedativeanalgesic agents: dexmedetomidine, remifentanil, ketamine, volatile anesthetics, and the role of peripheral mu antagonists. Crit Care Clin 2009 Jul; 25 (3): 451-69.
-
(2009)
Crit Care Clin
, vol.25
, Issue.3
, pp. 451-469
-
-
Panzer, O.1
Moitra, V.2
Sladen, R.N.3
-
12
-
-
70350780388
-
Dexmedetomidine use in general anaesthesia
-
Aug
-
Arcangeli A, D'Alò C, et al. Dexmedetomidine use in general anaesthesia. Curr Drug Targets 2009 Aug; 10 (8): 687-95.
-
(2009)
Curr Drug Targets
, vol.10
, Issue.8
, pp. 687-695
-
-
Arcangeli, A.1
D'Alò, C.2
-
13
-
-
0026780486
-
A hypnotic response to dexmedetomidine, an a2 agonist, is mediated in the locus coeruleus in rats
-
Jun
-
Correa-Sales C, Rabin BC, Maze M. A hypnotic response to dexmedetomidine, an a2 agonist, is mediated in the locus coeruleus in rats. Anesthesiology 1992 Jun; 76 (6): 948-52.
-
(1992)
Anesthesiology
, vol.76
, Issue.6
, pp. 948-952
-
-
Correa-Sales, C.1
Rabin, B.C.2
Maze, M.3
-
14
-
-
0033860761
-
The effects of increasing plasma concentrations of dexmedetomidine in humans
-
Ebert TJ, Hall JE, Barney JA, et al. The effects of increasing plasma concentrations of dexmedetomidine in humans. Anesthesiology 2000 Aug; 93 (2): 382-94. (Pubitemid 30620311)
-
(2000)
Anesthesiology
, vol.93
, Issue.2
, pp. 382-394
-
-
Ebert, T.J.1
Hall, J.E.2
Barney, J.A.3
Uhrich, T.D.4
Colinco, M.D.5
-
15
-
-
7244239373
-
Dexmedetomidine pharmacodynamics: Part I - Crossover comparison of the respiratory effects of dexmedetomidine and remifentanil in healthy volunteers
-
DOI 10.1097/00000542-200411000-00005
-
Hsu Y-W, Cortinez LI, Robertson KM, et al. Dexmedetomidine pharmacodynamics. Part I: crossover comparison of the respiratory effects of dexmedetomidine and remifentanil in healthy volunteers. Anesthesiology 2004 Nov; 101 (5): 1066-76. (Pubitemid 39430785)
-
(2004)
Anesthesiology
, vol.101
, Issue.5
, pp. 1066-1076
-
-
Hsu, Y.-W.1
Cortinez, L.I.2
Robertson, K.M.3
Keifer, J.C.4
Sum-Ping, S.T.5
Moretti, E.W.6
Young, C.C.7
Wright, D.R.8
MacLeod, D.B.9
Somma, J.10
-
16
-
-
7244220115
-
Dexmedetomidine pharmacodynamics: Part II - Crossover comparison of the analgesic effect of dexmedetomidine and remifentanil in healthy volunteers
-
DOI 10.1097/00000542-200411000-00006
-
Cortinez LI, Hsu YW, Sum-Ping ST, et al. Dexmedetomidine pharmacodynamics. Part II: crossover comparison of the analgesic effect of dexmedetomidine and remifentanil in healthy volunteers. Anesthesiology 2004 Nov; 101 (5): 1077-83. (Pubitemid 39430786)
-
(2004)
Anesthesiology
, vol.101
, Issue.5
, pp. 1077-1083
-
-
Cortinez, L.I.1
Hsu, Y.-W.2
Sum-Ping, S.T.3
Young, C.4
Keifer, J.C.5
MacLeod, D.6
Robertson, K.M.7
Wright, D.R.8
Moretti, E.W.9
Somma, J.10
-
17
-
-
0032855010
-
Effects of dexmedetomidine on isoflurane requirements in healthy volunteers. 1: Pharmacodynamic and pharmacokinetic interactions
-
Khan ZP, Munday IT, Jones RM, et al. Effects of dexmedetomidine on isoflurane requirements in healthy volunteers. 1: pharmacodynamic and pharmacokinetic interactions. Br J Anaesth 1999 Sep; 83 (3): 372-80. (Pubitemid 29412688)
-
(1999)
British Journal of Anaesthesia
, vol.83
, Issue.3
, pp. 372-380
-
-
Khan, Z.P.1
Munday, I.T.2
Jones, R.M.3
Thornton, C.4
Mant, T.G.5
Amin, D.6
-
18
-
-
0035137056
-
Effect of dexmedetomidine on propofol requirements in healthy subjects
-
DOI 10.1002/1520-6017(200102)90:2 <172::AID-JPS8>3.0.CO;2-J
-
Dutta S, Karol MD, Cohen T, et al. Effect of dexmedetomidine on propofol requirements in healthy subjects. J Pharm Sci 2001 Feb; 90 (2): 172-81. (Pubitemid 32158045)
-
(2001)
Journal of Pharmaceutical Sciences
, vol.90
, Issue.2
, pp. 172-181
-
-
Dutta, S.1
Karol, M.D.2
Cohen, T.3
Jones, R.M.4
Mant, T.5
-
19
-
-
0026677968
-
Effects of intravenous dexmedetomidine in humans: II. Hemodynamic changes
-
Bloor BC, Ward DS, Belleville JP, et al. Effects of intravenous dexmedetomidine in humans. II. Hemodynamic changes. Anesthesiology 1992 Dec; 77 (6): 1134-42. (Pubitemid 23001124)
-
(1992)
Anesthesiology
, vol.77
, Issue.6
, pp. 1134-1142
-
-
Bloor, B.C.1
Ward, D.S.2
Belleville, J.P.3
Maze, M.4
-
20
-
-
0036784783
-
Dexmedetomidineinduced sedation in volunteers decreases regional and global cerebral blood flow
-
Oct
-
Prielipp RC, Wall MH, Tobin JR, et al. Dexmedetomidineinduced sedation in volunteers decreases regional and global cerebral blood flow. Anesth Analg 2002 Oct; 95 (4): 1052-9.
-
(2002)
Anesth Analg
, vol.95
, Issue.4
, pp. 1052-1059
-
-
Prielipp, R.C.1
Wall, M.H.2
Tobin, J.R.3
-
21
-
-
38549161511
-
Effect of dexmedetomidine on cerebral blood flow velocity, cerebral metabolic rate, and carbon dioxide response in normal humans
-
DOI 10.1097/01.anes.0000299576.00302.4c, PII 0000054220080200000010
-
Drummond JC, Dao AV, Roth DM, et al. Effect of dexmedetomidine on cerebral blood flow velocity, cerebral metabolic rate, and carbon dioxide response in normal humans. Anesthesiology 2008; 108 (2): 225-32. (Pubitemid 351156732)
-
(2008)
Anesthesiology
, vol.108
, Issue.2
, pp. 225-232
-
-
Drummond, J.C.1
Dao, A.V.2
Roth, D.M.3
Cheng, C.-R.4
Atwater, B.I.5
Minokadeh, A.6
Pasco, L.C.7
Patel, P.M.8
-
22
-
-
79952982795
-
Dexmedetomidine inhibits gastric emptying and oro-caecal transit in healthy volunteers
-
Apr
-
Iirola T, Vilo S, Aantaa R, et al. Dexmedetomidine inhibits gastric emptying and oro-caecal transit in healthy volunteers. Br J Anaesth 2011 Apr; 106 (4): 522-7.
-
(2011)
Br J Anaesth
, vol.106
, Issue.4
, pp. 522-527
-
-
Iirola, T.1
Vilo, S.2
Aantaa, R.3
-
23
-
-
34547829701
-
Dexmedetomidine during coronary artery bypass grafting surgery: Is it neuroprotective? - A preliminary study
-
DOI 10.1111/j.1399-6576.2007.01377.x
-
Sulemanji DS, Donmez A, Aldemir D, et al. Dexmedetomidine during coronary artery bypass grafting surgery: is it neuroprotective? A preliminary study. Acta Anaesthesiol Scand 2007 Sep; 51 (8): 1093-8. (Pubitemid 47246914)
-
(2007)
Acta Anaesthesiologica Scandinavica
, vol.51
, Issue.8
, pp. 1093-1098
-
-
Sulemanji, D.S.1
Donmez, A.2
Aldemir, D.3
Sezgin, A.4
Turkoglu, S.5
-
24
-
-
70549084701
-
Effects of continuous infusion of dexmedetomidine on hemodynamics and blood oxygenation
-
Shiokawa Y, Inamori M, Tsukamoto I, et al. Effects of continuous infusion of dexmedetomidine on hemodynamics and blood oxygenation. Anesth Resusc 2009; 45 (3): 65-7.
-
(2009)
Anesth Resusc
, vol.45
, Issue.3
, pp. 65-67
-
-
Shiokawa, Y.1
Inamori, M.2
Tsukamoto, I.3
-
25
-
-
67650188992
-
Bispectral index-guided intraoperative sedation with dexmedetomidine and midazolam infusion in outpatient cataract surgery
-
May
-
Apan A, Doganci N, Ergan A, et al. Bispectral index-guided intraoperative sedation with dexmedetomidine and midazolam infusion in outpatient cataract surgery. Minerva Anestesiol 2009 May; 75 (5): 239-44.
-
(2009)
Minerva Anestesiol
, vol.75
, Issue.5
, pp. 239-244
-
-
Apan, A.1
Doganci, N.2
Ergan, A.3
-
26
-
-
41549149971
-
Dexmedetomidine and postoperative shivering in patients undergoing elective abdominal hysterectomy
-
DOI 10.1017/S0265021507003110, PII S0265021507003110
-
Elvan EG, Oc B, Uzun S, et al. Dexmedetomidine and postoperative shivering in patients undergoing elective abdominal hysterectomy. Eur J Anaesthesiol 2008 May; 25 (5): 357-64. (Pubitemid 351465526)
-
(2008)
European Journal of Anaesthesiology
, vol.25
, Issue.5
, pp. 357-364
-
-
Elvan, E.G.1
Oc, B.2
Uzun, S.3
Karabulut, E.4
Coskun, F.5
Aypar, U.6
-
27
-
-
0032705173
-
Preliminary UK experience of dexmedetomidine, a novel agent for postoperative sedation in the intensive care unit
-
Dec
-
Venn RM, Bradshaw CJ, Spencer R, et al. Preliminary UK experience of dexmedetomidine, a novel agent for postoperative sedation in the intensive care unit. Anaesthesia 1999 Dec; 54 (12): 1136-42.
-
(1999)
Anaesthesia
, vol.54
, Issue.12
, pp. 1136-1142
-
-
Venn, R.M.1
Bradshaw, C.J.2
Spencer, R.3
-
28
-
-
0347363657
-
The efficacy of dexmedetomidine versus morphine for postoperative analgesia after major inpatient surgery
-
Arain SR, Ruehlow RM, Uhrich TD, et al. The efficacy of dexmedetomidine versus morphine for postoperative analgesia after major inpatient surgery. Anesth Analg 2004 Jan; 98 (1): 153-8. (Pubitemid 38029869)
-
(2004)
Anesthesia and Analgesia
, vol.98
, Issue.1
, pp. 153-158
-
-
Arain, S.R.1
Ruehlow, R.M.2
Uhrich, T.D.3
Ebert, T.J.4
-
29
-
-
37249031114
-
Effect of dexmedetomidine IV on the duration of spinal anesthesia with prilocaine: A double-blind, prospective study in adult surgical patients
-
DOI 10.1016/j.curtheres.2007.10.006, PII S0011393X07000872
-
TekinM, Kati I, Tomak Y, et al. Effect of dexmedetomidine IV on the duration of spinal anesthesia with prilocaine: a double-blind, prospective study in adult surgical patients. Curr Ther Res Clin Exp 2007; 68 (5): 313-24. (Pubitemid 350266607)
-
(2007)
Current Therapeutic Research - Clinical and Experimental
, vol.68
, Issue.5
, pp. 313-324
-
-
Tekin, M.1
Kati, I.2
Tomak, Y.3
Kisli, E.4
-
30
-
-
34249004884
-
Effects of dexmedetomidine on the duration of anaesthesia and wakefulness in bupivacaine epidural block
-
DOI 10.1017/S0265021506002237, PII S0265021506002237
-
Coskuner I, Tekin M, Kati I, et al. Effects of dexmedetomidine on the duration of anaesthesia and wakefulness in bupivacaine epidural block. Eur J Anaesthesiol 2007 Jun; 24 (6): 535-40. (Pubitemid 46787799)
-
(2007)
European Journal of Anaesthesiology
, vol.24
, Issue.6
, pp. 535-540
-
-
Coskuner, I.1
Tekin, M.2
Kati, I.3
Yagmur, C.4
Elcicek, K.5
-
31
-
-
0035167022
-
Comparison between dexmedetomidine and propofol for sedation in the intensive care unit: Patient and clinician perceptions
-
DOI 10.1093/bja/87.5.684
-
Venn RM, Grounds RM. Comparison between dexmedetomidine and propofol for sedation in the intensive care unit: patient and clinician perceptions. Br J Anaesth 2001 Nov; 87 (5): 684-90. (Pubitemid 33069556)
-
(2001)
British Journal of Anaesthesia
, vol.87
, Issue.5
, pp. 684-690
-
-
Venn, R.M.1
Grounds, R.M.2
-
32
-
-
0035030213
-
Effects of dexmedetomidine on adrenocortical function, and the cardiovascular, endocrine and inflammatory responses in post-operative patients needing sedation in the intensive care unit
-
DOI 10.1093/bja/86.5.650
-
Venn RM, Bryant A, Hall GM, et al. Effects of dexmedetomidine on adrenocortical function, and the cardiovascular, endocrine and inflammatory responses in post-operative patients needing sedation in the intensive care unit. Br J Anaesth 2001 May; 86 (5): 650-6. (Pubitemid 32409406)
-
(2001)
British Journal of Anaesthesia
, vol.86
, Issue.5
, pp. 650-656
-
-
Venn, R.M.1
Bryant, A.2
Hall, G.M.3
Grounds, R.M.4
-
34
-
-
79961154846
-
Dexmedetomidine's effect on QT interval and QT dispersion undergoing total intravenous anaesthesia [abstract]
-
Mar 2-7; Cape Town
-
Inan SA, Ozkose Z. Dexmedetomidine's effect on QT interval and QT dispersion undergoing total intravenous anaesthesia [abstract]. 14th World Congress of Anaesthesiologists; 2008 Mar 2-7; Cape Town.
-
(2008)
14th World Congress of Anaesthesiologists
-
-
Inan, S.A.1
Ozkose, Z.2
-
36
-
-
79954420390
-
A randomized, controlled trial on dexmedetomidine for providing adequate sedation and hemodynamic control for awake, diagnostic transesophageal echocardiography
-
Apr
-
Cooper L, Candiotti K, Gallagher C, et al. A randomized, controlled trial on dexmedetomidine for providing adequate sedation and hemodynamic control for awake, diagnostic transesophageal echocardiography. J Cardiothorac Vasc Anesth 2011 Apr; 25 (2): 233-7.
-
(2011)
J Cardiothorac Vasc Anesth
, vol.25
, Issue.2
, pp. 233-237
-
-
Cooper, L.1
Candiotti, K.2
Gallagher, C.3
-
37
-
-
67650503408
-
Intravenous dexmedetomidine prolongs bupivacaine spinal analgesia
-
Jun
-
Al-MustafaMM, Badran IZ, Abu-Ali HM, et al. Intravenous dexmedetomidine prolongs bupivacaine spinal analgesia. Middle East J Anesthesiol 2009 Jun; 20 (2): 225-31.
-
(2009)
Middle East J Anesthesiol
, vol.20
, Issue.2
, pp. 225-231
-
-
Al-Mustafa, M.M.1
Badran, I.Z.2
Abu-Ali, H.M.3
-
38
-
-
74349096562
-
Intravenous dexmedetomidine, but not midazolam, prolongs bupivacaine spinal anesthesia
-
Jan
-
Kaya FN, Yavascaoglu B, Turker G, et al. Intravenous dexmedetomidine, but not midazolam, prolongs bupivacaine spinal anesthesia. Can J Anaesth 2010 Jan; 57 (1): 39-45.
-
(2010)
Can J Anaesth
, vol.57
, Issue.1
, pp. 39-45
-
-
Kaya, F.N.1
Yavascaoglu, B.2
Turker, G.3
-
39
-
-
9744268250
-
A comparative study of the use of dexmedetomidine and propofol as sedatives for mechanically ventilated patients in ICU
-
Abdulatif M, Hamed HM, el-Borolossy K, et al. A comparative study of the use of dexmedetomidine and propofol as sedatives for mechanically ventilated patients in ICU. Egypt J Anaesth 2004; 20 (4): 437-42. (Pubitemid 39585935)
-
(2004)
Egyptian Journal of Anaesthesia
, vol.20
, Issue.4
, pp. 437-442
-
-
Abdulatif, M.1
Hamed, H.M.2
El-Borolossy, K.3
Teima, D.O.4
-
40
-
-
77951088585
-
The effect of dexmedetomidine sedation on brachial plexus block in patients with end-stage renal disease
-
Oct
-
Rutkowska K, Knapik P, Misiolek H. The effect of dexmedetomidine sedation on brachial plexus block in patients with end-stage renal disease. Eur J Anaesthesiol 2009 Oct; 26 (10): 851-5.
-
(2009)
Eur J Anaesthesiol
, vol.26
, Issue.10
, pp. 851-855
-
-
Rutkowska, K.1
Knapik, P.2
Misiolek, H.3
-
41
-
-
0142094416
-
2-adrenoceptor agonist dexmedetomidine in postsurgical sedation in the intensive care unit
-
DOI 10.1177/0885066602239122
-
Martin E, Ramsay G, Mantz J, et al. The role of the a2-adrenoceptor agonist dexmedetomidine in postsurgical sedation in the intensive care unit. J Intensive Care Med 2003 Jan-2003 28; 18 (1): 29-41. (Pubitemid 44526587)
-
(2003)
Journal of Intensive Care Medicine
, vol.18
, Issue.1
, pp. 29-41
-
-
Martin, E.1
Ramsay, G.2
Mantz, J.3
Sum-Ping, S.T.J.4
-
42
-
-
78649664705
-
A phase IIIb, randomized, double-blind, placebo-controlled, multicenter study evaluating the safety and efficacy of dexmedetomidine for sedation during awake fiberoptic intubation
-
Nov-Dec
-
Bergese SD, Candiotti KA, Bokesch PM, et al. A phase IIIb, randomized, double-blind, placebo-controlled, multicenter study evaluating the safety and efficacy of dexmedetomidine for sedation during awake fiberoptic intubation. Am J Ther 2010 Nov-Dec; 17 (6): 586-95.
-
(2010)
Am J Ther
, vol.17
, Issue.6
, pp. 586-595
-
-
Bergese, S.D.1
Candiotti, K.A.2
Bokesch, P.M.3
-
43
-
-
74049113764
-
Monitored anesthesia care with dexmedetomidine: A prospective randomized double-blind multicenter trial
-
Jan
-
Candiotti KA, Bergese SD, Bokesch PM, et al. Monitored anesthesia care with dexmedetomidine: a prospective, randomized, double-blind, multicenter trial. Anesth Analg 2010 Jan; 110 (1): 47-56.
-
(2010)
Anesth Analg
, vol.110
, Issue.1
, pp. 47-56
-
-
Candiotti, K.A.1
Bergese, S.D.2
Bokesch, P.M.3
-
44
-
-
0036257713
-
Pharmacokinetics of dexmedetomidine infusions for sedation of postoperative patients requiring intensive care
-
DOI 10.1093/bja/88.5.669
-
Venn RM, Karol MD, Grounds RM. Pharmacokinetics of dexmedetomidine infusions for sedation of postoperative patients requiring intensive caret. Br J Anaesth 2002 May; 88 (5): 669-75. (Pubitemid 34498595)
-
(2002)
British Journal of Anaesthesia
, vol.88
, Issue.5
, pp. 669-675
-
-
Venn, R.M.1
Karol, M.D.2
Grounds, R.M.3
-
45
-
-
0034761921
-
The pharmacokinetics of dexmedetomidine in volunteers with severe renal impairment
-
De Wolf AM, Fragen RJ, Avram MJ, et al. The pharmacokinetics of dexmedetomidine in volunteers with severe renal impairment. Anesth Analg 2001 Nov; 93 (5): 1205-9. (Pubitemid 33021018)
-
(2001)
Anesthesia and Analgesia
, vol.93
, Issue.5
, pp. 1205-1209
-
-
De Wolf, A.M.1
Fragen, R.J.2
Avram, M.J.3
Fitzgerald, P.C.4
Rahimi-Danesh, F.5
-
46
-
-
84856616940
-
-
US Food and Drug Administration. Center for Drug Evaluation and Research [Accessed 2011 Jul 15]
-
US Food and Drug Administration. Center for Drug Evaluation and Research. Medical review(s). Part 1 [online]. Available from URL: http://www.accessdata. fda.gov/drugsatfda-docs/nda/99/21-038-Precedex-medr-P1.pdf [Accessed 2011 Jul 15].
-
Medical Review(s). Part 1 [Online]
-
-
-
47
-
-
84856620011
-
-
US Food and Drug Administration. Center for Drug Evaluation and Research [Accessed 2011 Jul 15]
-
US Food and Drug Administration. Center for Drug Evaluation and Research. Medical review(s). Part 2 [online]. Available from URL: http://www.accessdata. fda.gov/drugsatfda-docs/nda/99/21-038-Precedex-medr-P2.pdf [Accessed 2011 Jul 15].
-
Medical Review(s). Part 2 [Online]
-
-
-
48
-
-
0025046841
-
Validity and reliability of the Observer's Assessment of Alertness/Sedation Scale: Study with intravenous midazolam
-
Chernik DA, Gillings D, Laine H, et al. Validity and reliability of the Observer's Assessment of Alertness/Sedation Scale: study with intravenous midazolam. J Clin Psychopharmacol 1990 Aug; 10 (4): 244-51. (Pubitemid 20319177)
-
(1990)
Journal of Clinical Psychopharmacology
, vol.10
, Issue.4
, pp. 244-251
-
-
Chernik, D.A.1
Gillings, D.2
Laine, H.3
Hendler, J.4
Silver, J.M.5
Davidson, A.B.6
Schwam, E.M.7
Siegel, J.L.8
-
49
-
-
67650921091
-
Dexmedetomidine and the reduction of postoperative delirium after cardiac surgery
-
May-Jun 30
-
Maldonado JR, Wysong A, van der Starre PJ, et al. Dexmedetomidine and the reduction of postoperative delirium after cardiac surgery. Psychosomatics 2009 May-Jun 30; 50 (3): 206-17.
-
(2009)
Psychosomatics
, vol.50
, Issue.3
, pp. 206-217
-
-
Maldonado, J.R.1
Wysong, A.2
Van Der Starre, P.J.3
-
50
-
-
0037255106
-
Postoperative analgesia and sedation in the adult intensive care unit: A guide to drug selection
-
DOI 10.2165/00003495-200363080-00003
-
Liu LL, Gropper MA. Postoperative analgesia and sedation in the adult intensive care unit: a guide to drug selection. Drugs 2003; 63 (8): 755-67. (Pubitemid 36428445)
-
(2003)
Drugs
, vol.63
, Issue.8
, pp. 755-767
-
-
Liu, L.L.1
Gropper, M.A.2
-
51
-
-
0036152552
-
Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult
-
Jacobi J, Fraser GL, Coursin DB, et al. Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult. Crit Care Med 2002 Jan; 30 (1): 119-41. (Pubitemid 34112188)
-
(2002)
Critical Care Medicine
, vol.30
, Issue.1
, pp. 119-141
-
-
Jacobi, J.1
Fraser, G.L.2
Coursin, D.B.3
Riker, R.R.4
Fontaine, D.5
Wittbrodt, E.T.6
Chalfin, D.B.7
Masica, M.F.8
Bjerke, H.S.9
Coplin, W.M.10
Crippen, D.W.11
Fuchs, B.D.12
Kelleher, R.M.13
Marik, P.E.14
Nasraway Jr., S.A.15
Murray, M.J.16
Peruzzi, W.T.17
Lumb, P.D.18
-
52
-
-
77950790017
-
Optimizing sustained use of sedation inmechanically ventilated patients: Focus on safety
-
Jan
-
Arnold HM, Hollands JM, Skrupky LP, et al. Optimizing sustained use of sedation inmechanically ventilated patients: focus on safety. Curr Drug Saf 2010 Jan; 5 (1): 6-12.
-
(2010)
Curr Drug Saf
, vol.5
, Issue.1
, pp. 6-12
-
-
Arnold, H.M.1
Hollands, J.M.2
Skrupky, L.P.3
-
53
-
-
47749137822
-
Sedation and delirium in the intensive care unit: An Australian and New Zealand perspective
-
Shehabi Y, Botha JA, Boyle MS, et al. Sedation and delirium in the intensive care unit: an Australian and New Zealand perspective. Anaesth Intensive Care 2008 Jul; 36 (4): 570-8. (Pubitemid 352030246)
-
(2008)
Anaesthesia and Intensive Care
, vol.36
, Issue.4
, pp. 570-578
-
-
Shehabi, Y.1
Botha, J.A.2
Boyle, M.S.3
Ernest, D.4
Freebairn, R.C.5
Jenkins, I.R.6
Roberts, B.L.7
Seppelt, I.M.8
-
54
-
-
68049143180
-
Advances in sedation for critically ill patients
-
Jun
-
Morandi A, Watson PL, Trabucchi M, et al. Advances in sedation for critically ill patients. Minerva Anestesiol 2009 Jun; 75 (6): 385-91.
-
(2009)
Minerva Anestesiol
, vol.75
, Issue.6
, pp. 385-391
-
-
Morandi, A.1
Watson, P.L.2
Trabucchi, M.3
-
55
-
-
0031888397
-
2-adrenoceptor agonist
-
Jaakola M-L. Dexmedetomidine as a preanaesthetic agent: phase I-III studies with a novel, specific a2-adrenoceptor agonist. Acta Anaesthesiol Scand 1998; 42 (2): 276-7. (Pubitemid 28067902)
-
(1998)
Acta Anaesthesiologica Scandinavica
, vol.42
, Issue.2
, pp. 276-277
-
-
Jaakola, M.-L.1
-
56
-
-
59649127447
-
Dexmedetomidine vs midazolam for sedation of critically ill patients: A randomized trial
-
Feb
-
Riker RR, Shehabi Y, Bokesch PM, et al. Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial. JAMA 2009 Feb; 301 (5): 489-99.
-
(2009)
JAMA
, vol.301
, Issue.5
, pp. 489-499
-
-
Riker, R.R.1
Shehabi, Y.2
Bokesch, P.M.3
-
57
-
-
37149040245
-
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: The MENDS randomized controlled trial
-
DOI 10.1001/jama.298.22.2644
-
Pandharipande PP, Pun BT, Herr DL, et al. Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial. JAMA 2007 Dec; 298 (22): 2644-53. (Pubitemid 350254956)
-
(2007)
Journal of the American Medical Association
, vol.298
, Issue.22
, pp. 2644-2653
-
-
Pandharipande, P.P.1
Pun, B.T.2
Herr, D.L.3
Maze, M.4
Girard, T.D.5
Miller, R.R.6
Shintani, A.K.7
Thompson, J.L.8
Jackson, J.C.9
Deppen, S.A.10
Stiles, R.A.11
Dittus, R.S.12
Bernard, G.R.13
Ely, E.W.14
-
60
-
-
44649125433
-
Dexmedetomidine infusion during laparoscopic bariatric surgery: The effect on recovery outcome variables
-
Jun
-
Tufanogullari B, White PF, Peixoto MP, et al. Dexmedetomidine infusion during laparoscopic bariatric surgery: the effect on recovery outcome variables. Anesth Analg 2008 Jun; 106 (6): 1741-8.
-
(2008)
Anesth Analg
, vol.106
, Issue.6
, pp. 1741-1748
-
-
Tufanogullari, B.1
White, P.F.2
Peixoto, M.P.3
-
61
-
-
33644677786
-
Fentanyl or dexmedetomidine combined with desflurane for bariatric surgery
-
DOI 10.1016/j.jclinane.2005.05.009, PII S0952818005003260
-
Feld JM, Hoffman WE, Stechert MM, et al. Fentanyl or dexmedetomidine combined with desflurane for bariatric surgery. J Clin Anesth 2006; 18 (1): 24-8. (Pubitemid 43330764)
-
(2006)
Journal of Clinical Anesthesia
, vol.18
, Issue.1
, pp. 24-28
-
-
Feld, J.M.1
Hoffman, W.E.2
Stechert, M.M.3
Hoffman, I.W.4
Ananda, R.C.5
-
62
-
-
0038265854
-
Alpha-2 adrenergic agonists to prevent perioperative cardiovascular complications: A meta-analysis
-
DOI 10.1016/S0002-9343(03)00165-7
-
Wijeysundera DN, Naik JS, Beattie WS. Alpha-2 adrenergic agonists to prevent perioperative cardiovascular complications: ameta-analysis. AmJMed 2003 Jun 15; 114 (9): 742-52. (Pubitemid 36776356)
-
(2003)
American Journal of Medicine
, vol.114
, Issue.9
, pp. 742-752
-
-
Wijeysundera, D.N.1
Naik, J.S.2
Beattie, W.S.3
-
63
-
-
0031056866
-
Dexmedetomidine as an anesthetic adjunct in coronary artery bypass grafting
-
DOI 10.1097/00000542-199702000-00009
-
Jalonen J, Hynynen M, Kuitunen A, et al. Dexmedetomidine as an anesthetic adjunct in coronary artery bypass grafting. Anesthesiology 1997 Feb; 86 (2): 331-45. (Pubitemid 27093378)
-
(1997)
Anesthesiology
, vol.86
, Issue.2
, pp. 331-345
-
-
Jalonen, J.1
Hynynen, M.2
Kuitunen, A.3
Heikkila, H.4
Perttila, J.5
Salmenpera, M.6
Valtonen, M.7
Aantaa, R.8
Kallio, A.9
-
64
-
-
33750364365
-
The effects of pre-operative dexmedetomidine infusion on hemodynamics in patients with pulmonary hypertension undergoing mitral valve replacement surgery
-
DOI 10.1111/j.1399-6576.2006.01136.x
-
But AK, Ozgul U, Erdil F, et al. The effects of pre-operative dexmedetomidine infusion on hemodynamics in patients with pulmonary hypertension undergoing mitral valve replacement surgery. Acta Anaesthesiol Scand 2006 Nov; 50 (10): 1207-12. (Pubitemid 44624299)
-
(2006)
Acta Anaesthesiologica Scandinavica
, vol.50
, Issue.10
, pp. 1207-1212
-
-
But, A.K.1
Ozgul, U.2
Erdil, F.3
Gulhas, N.4
Toprak, H.I.5
Durmus, M.6
Ersoy, M.O.7
-
65
-
-
74949137504
-
A costminimization analysis of dexmedetomidine compared with midazolam for long-term sedation in the intensive care unit
-
Feb
-
Dasta JF, Kane-Gill SL, Pencina M, et al. A costminimization analysis of dexmedetomidine compared with midazolam for long-term sedation in the intensive care unit. Crit Care Med 2010 Feb; 38 (2): 497-503.
-
(2010)
Crit Care Med
, vol.38
, Issue.2
, pp. 497-503
-
-
Dasta, J.F.1
Kane-Gill, S.L.2
Pencina, M.3
-
66
-
-
78650305502
-
Delirium duration and mortality in lightly sedated mechanically ventilated intensive care patients
-
Dec
-
Shehabi Y, Riker RR, Bokesch PM, et al. Delirium duration and mortality in lightly sedated, mechanically ventilated intensive care patients. Crit Care Med 2010 Dec; 38 (12): 2311-8.
-
(2010)
Crit Care Med
, vol.38
, Issue.12
, pp. 2311-2318
-
-
Shehabi, Y.1
Riker, R.R.2
Bokesch, P.M.3
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