The pharmacokinetics of dexmedetomidine in volunteers with severe renal impairment

Anesthesia and Analgesia

Volumn 93, Issue 5, 2001, Pages 1205-1209

  De Wolf, Andre M ^a,b   Fragen, Robert J ^a   Avram, Michael J ^a   Fitzgerald, Paul C ^a   Rahimi Danesh, Farhad ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b UNIVERSITY OF CHICAGO MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEXMEDETOMIDINE;

ADULT; ARTICLE; CLINICAL ARTICLE; COMPARTMENT MODEL; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG METABOLISM; FEMALE; HEMODYNAMICS; HUMAN; KIDNEY FAILURE; MALE; PRIORITY JOURNAL; SEDATION;

EID: 0034761921     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-200111000-00031     Document Type: Article

References (12)

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6. Picogram level determination of medetomidine in dog serum by capillary gas chromatography with negative ion chemical ionization mass spectrometry
7. Compartmental models: Theory and practice using the SAAM II software system
8. Developing and testing integrated multicompartment models to describe a single-input multiple-output study using the SAAM II Software system
9. The pharmacokinetics and hemodynamic effects of intravenous and intramuscular dexmedetomidine hydrochloride in adult human volunteers
10. Pharmacokinetics and pharmacodynamics of transdermal dexmedetomidine
11. Pharmacokinetics of alfentanil in chronic renal failure
12. Pharmacodynamics and pharmacokinetics of intramuscular dexmedetomidine