A phase IIIb, randomized, double-blind, placebo-controlled, multicenter study evaluating the safety and efficacy of dexmedetomidine for sedation during awake fiberoptic intubation

American Journal of Therapeutics

Volumn 17, Issue 6, 2010, Pages 586-595

  Bergese, Sergio D ^a   Candiotti, Keith A ^b   Bokesch, Paula M ^c   Zura, Andrew ^d   Wisemandle, Wayne ^c   Bekker, Alex Y ^e  

^a OHIO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF MIAMI   (United States)

^c Hospira Inc   (United States)

^d LERNER RESEARCH INSTITUTE   (United States)

^e NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

American Society of Anesthesiologists; awake fiberoptic intubation; dexmedetomidine; Mallampati Score; Ramsay Sedation Scale

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DEXMEDETOMIDINE; EPHEDRINE; ESMOLOL; MIDAZOLAM; NICARDIPINE; PHENYLEPHRINE; PLACEBO; SODIUM CHLORIDE;

ADULT; AGED; ANESTHESIST; ARTICLE; BRADYCARDIA; CLINICAL TRIAL; CONTINUOUS INFUSION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; DRUG WITHDRAWAL; END TIDAL CARBON DIOXIDE TENSION; FEMALE; HEART RATE; HUMAN; HYPERTENSION; HYPOTENSION; INTUBATION; LOADING DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MEAN ARTERIAL PRESSURE; MULTICENTER STUDY; PATIENT SATISFACTION; PHASE 3 CLINICAL TRIAL; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROSPECTIVE STUDY; RAMSAY SEDATION SCALE; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; RESPIRATION DEPRESSION; SEDATION; SIDE EFFECT; SYSTOLIC BLOOD PRESSURE; WAKEFULNESS;

BLOOD PRESSURE; CONSCIOUS SEDATION; DEXMEDETOMIDINE; DOUBLE-BLIND METHOD; FEMALE; FIBER OPTIC TECHNOLOGY; HEART RATE; HUMANS; HYPNOTICS AND SEDATIVES; INTUBATION, INTRATRACHEAL; MALE; MIDAZOLAM; MIDDLE AGED; PATIENT SATISFACTION; PROSPECTIVE STUDIES;

EID: 78649664705     PISSN: 10752765     EISSN: None     Source Type: Journal    
DOI: 10.1097/MJT.0b013e3181d69072     Document Type: Article

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