Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: The MENDS randomized controlled trial

JAMA

Volumn 298, Issue 22, 2007, Pages 2644-2653

  Pandharipande, Pratik P ^a,b,e   Pun, Brenda T ^b   Herr, Daniel L ^d   Maze, Mervyn ^e   Girard, Timothy D ^b   Miller, Russell R ^b   Shintani, Ayumi K ^b   Thompson, Jennifer L ^b   Jackson, James C ^b,c   Deppen, Stephen A ^b   Stiles, Renee A ^b   Dittus, Robert S ^b,c   Bernard, Gordon R ^b   Ely, E Wesley ^b,c  

^a 526 MAB   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Education and Clinical Center (GRECC)   (United States)

^d WASHINGTON HOSPITAL CENTER   (United States)

^e IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DEXMEDETOMIDINE; LORAZEPAM;

ADULT; AGED; ARTICLE; ARTIFICIAL VENTILATION; BRAIN DYSFUNCTION; CLINICAL TRIAL; COMA; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DELIRIUM; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG DOSE TITRATION; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; HEALTH CARE COST; HEART ATRIUM FIBRILLATION; HUMAN; MAJOR CLINICAL STUDY; MORTALITY; MULTICENTER STUDY; OUTCOME ASSESSMENT; PATIENT MONITORING; PREVALENCE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEDATION; SINUS BRADYCARDIA; TREATMENT OUTCOME;

EID: 37149040245     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.298.22.2644     Document Type: Article

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