The RNA surveillance protein SMG1 activates p53 in response to DNA double-strand breaks but not exogenously oxidized mRNA

Cell Cycle

Volumn 10, Issue 15, 2011, Pages 2561-2567

  Gewandter, Jennifer S ^a   Bambara, Robert A ^a   O'Reilly, Michael A ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

DNA double strand breaks; Nonsense mediated mRNA decay (NMD); Oxidative stress; Phosphatidylinositiol 3 kinase like kinases (PIKKs); RNA damage

Indexed keywords

DOUBLE STRANDED DNA; ENDONUCLEASE; GREEN FLUORESCENT PROTEIN; MESSENGER RNA; PROTEIN; PROTEIN P53; PROTEIN SMG1; PROTEIN UPF1; PROTEIN UPF2; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CELL DAMAGE; CONTROLLED STUDY; DNA DETERMINATION; DNA STRAND BREAKAGE; HUMAN; HUMAN CELL; HYPEROXIA; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

EID: 79961115383     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.10.15.16347     Document Type: Article

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