Regulatory T cells control type i food allergy to beta-lactoglobulin in mice

International Archives of Allergy and Immunology

Volumn 156, Issue 4, 2011, Pages 387-396

  Kanjarawi, Reem ^a   Dercamp, Christophe ^a   Etchart, Nathalie ^a   Adel Patient, Karine ^b   Nicolas, Jean François ^a   Dubois, Bertrand ^a   Kaiserlian, Dominique ^a  

^a University Lyon i   (France)

^b Bâtiment 136 CEA de Saclay   (France)

Author keywords

CD4CD25 regulatory T cells; Cow's milk; Food allergy; Mast cells

Indexed keywords

BASILIXIMAB; BETA LACTOGLOBULIN; CHOLERA TOXIN; CHYMASE; GAMMA INTERFERON; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2A ANTIBODY; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CYTOKINE PRODUCTION; DISEASE SEVERITY; FEMALE; FOOD ALLERGY; IMMEDIATE TYPE HYPERSENSITIVITY; INTESTINE CELL; MAST CELL; MESENTERY LYMPH NODE; MILK; MILK ALLERGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SENSITIZATION; TH1 CELL; TH2 CELL;

ADMINISTRATION, ORAL; ANIMALS; ANTIBODIES; CYTOKINES; FEMALE; FOOD HYPERSENSITIVITY; IMMUNIZATION; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; INTESTINES; LACTOGLOBULINS; MAST CELLS; MICE; MICE, INBRED C3H; T-LYMPHOCYTES, REGULATORY; TH1 CELLS; TH2 CELLS;

EID: 79961104052     PISSN: 10182438     EISSN: 14230097     Source Type: Journal    
DOI: 10.1159/000323940     Document Type: Article

References (34)

1. Sampson HA: Update on food allergy. J Allergy Clin Immunol 2004; 113: 805-819; quiz 820. (Pubitemid 38608586)
2. Skripak JM, Matsui EC, Mudd K, Wood RA: The natural history of IgE-mediated cow's milk allergy. J Allergy Clin Immunol 2007; 120: 1172-1177. (Pubitemid 350029907)
3. Dubois B, Chapat L, Goubier A, Papiernik M, Nicolas JF, Kaiserlian D: Innate CD4+CD25+ regulatory T cells are required for oral tolerance and inhibition of CD8+ T cells mediating skin inflammation. Blood 2003; 102: 3295-3301. (Pubitemid 37314769)
4. Dubois B, Joubert G, Gomez de Aguero M, Gouanvic M, Goubier A, Kaiserlian D: Sequential role of plasmacytoid dendritic cells and regulatory T cells in oral tolerance. Gastroenterology 2009; 137: 1019-1028.
5. Dubois B, Goubier A, Joubert G, Kaiserlian D: Oral tolerance and regulation of mucosal immunity. Cell Mol Life Sci 2005; 62: 1322-1332. (Pubitemid 40853819)
6. Shevach EM: Mechanisms of Foxp3+ T regulatory cell-mediated suppression. Immunity 2009; 30: 636-645.
7. Powell BR, Buist NR, Stenzel P: An X-linked syndrome of diarrhea, polyendocrinopathy, and fatal infection in infancy. J Pediatr 1982; 100: 731-737. (Pubitemid 12155977)
8. Wildin RS, Ramsdell F, Peake J, Faravelli F, Casanova JL, Buist N, Levy-Lahad E, Mazzella M, Goulet O, Perroni L, Bricarelli FD, Byrne G, McEuen M, Proll S, Appleby M, Brunkow ME: X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. Nat Genet 2001; 27: 18-20. (Pubitemid 32044512)
9. Torgerson TR, Linane A, Moes N, Anover S, Mateo V, Rieux-Laucat F, Hermine O, Vijay S, Gambineri E, Cerf-Bensussan N, Fischer A, Ochs HD, Goulet O, Ruemmele FM: Severe food allergy as a variant of IPEX syndrome caused by a deletion in a noncoding region of the Foxp3 gene. Gastroenterology 2007; 132: 1705-1717. (Pubitemid 46695720)
10. Beyer K, Castro R, Birnbaum A, Benkov K, Pittman N, Sampson HA: Human milk-specific mucosal lymphocytes of the gastrointestinal tract display a Th2 cytokine profile. J Allergy Clin Immunol 2002; 109: 707-713. (Pubitemid 34327201)
11. Karlsson MR, Rugtveit J, Brandtzaeg P: Allergen-responsive CD4+CD25+ regulatory T cells in children who have outgrown cow's milk allergy. J Exp Med 2004; 199: 1679-1688. (Pubitemid 38822001)
12. Shreffler WG, Wanich N, Moloney M, Nowak-Wegrzyn A, Sampson HA: Association of allergen-specific regulatory T cells with the onset of clinical tolerance to milk protein. J Allergy Clin Immunol 2009; 123: 43-52 e47.
13. Moon TC, St Laurent CD, Morris KE, Marcet C, Yoshimura T, Sekar Y, Befus AD: Advances in mast cell biology: new understanding of heterogeneity and function. Mucosal Immunol 2010; 3: 111-128.
14. Metcalfe DD, Baram D, Mekori YA: Mast cells. Physiol Rev 1997; 77: 1033-1079. (Pubitemid 27459579)
15. Adel-Patient K, Nahori MA, Proust B, Lapa e Silva JR, Creminon C, Wal JM, Vargaftig BB: Elicitation of the allergic reaction in-lactoglobulin-sensitized Balb/c mice: biochemical and clinical manifestations differ according to the structure of the allergen used for challenge. Clin Exp Allergy 2003; 33: 376-385. (Pubitemid 36315180)
16. Li XM, Schofield BH, Huang CK, Kleiner GI, Sampson HA: A murine model of IgE-mediated cow's milk hypersensitivity. J Allergy Clin Immunol 1999; 103: 206-214. (Pubitemid 29095823)
17. Frossard CP, Hauser C, Eigenmann PA: Antigen-specific secretory IgA antibodies in the gut are decreased in a mouse model of food allergy. J Allergy Clin Immunol 2004; 114: 377-382. (Pubitemid 39119040)
18. Frossard CP, Tropia L, Hauser C, Eigenmann PA: Lymphocytes in Peyer patches regulate clinical tolerance in a murine model of food allergy. J Allergy Clin Immunol 2004; 113: 958-964. (Pubitemid 38608607)
19. Adel-Patient K, Creminon C, Bernard H, Clement G, Negroni L, Frobert Y, Grassi J, Wal JM, Chatel JM: Evaluation of a high IgEresponder mouse model of allergy to bovine-lactoglobulin (BLG): development of sandwich immunoassays for total and allergen-specific IgE, IgG1 and IgG2A in BLGsensitized mice. J Immunol Methods 2000; 235: 21-32. (Pubitemid 30089780)
20. Strobel S, Miller HR, Ferguson A: Human intestinal mucosal mast cells: evaluation of fixation and staining techniques. J Clin Pathol 1981; 34: 851-858. (Pubitemid 11060145)
21. Kohm AP, McMahon JS, Podojil JR, Begolka WS, DeGutes M, Kasprowicz DJ, Ziegler SF, Miller SD: Cutting edge: anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+CD25+ T regulatory cells. J Immunol 2006; 176: 3301-3305. (Pubitemid 43363974)
22. Couper KN, Blount DG, de Souza JB, Suffia I, Belkaid Y, Riley EM: Incomplete depletion and rapid regeneration of Foxp3+ regulatory T cells following anti-CD25 treatment in malaria-infected mice. J Immunol 2007; 178: 4136-4146. (Pubitemid 46492363)
23. Tenorio EP, Olguin JE, Fernandez J, Vieyra P, Saavedra R: Reduction of Foxp3+ cells by depletion with the PC61 mAb induces mortality in resistant BALB/c mice infected with Toxoplasma gondii. J Biomed Biotechnol 2009; 2010: 786078.
24. Berin MC, Zheng Y, Domaradzki M, Li XM, Sampson HA: Role of TLR4 in allergic sensitization to food proteins in mice. Allergy 2006; 61: 64-71. (Pubitemid 43381193)
25. Eddahri F, Oldenhove G, Denanglaire S, Urbain J, Leo O, Andris F: CD4+ CD25+ regulatory T cells control the magnitude of T-dependent humoral immune responses to exogenous antigens. Eur J Immunol 2006; 36: 855-863.
26. Lim HW, Hillsamer P, Kim CH: Regulatory T cells can migrate to follicles upon T cell activation and suppress GC-Th cells and GCTh cell-driven B cell responses. J Clin Invest 2004; 114: 1640-1649. (Pubitemid 40385555)
27. Aseffa A, Gumy A, Launois P, MacDonald HR, Louis JA, Tacchini-Cottier F: The early IL-4 response to leishmania major and the resulting Th2 cell maturation steering progressive disease in Balb/c mice are subject to the control of regulatory CD4+CD25+ T cells. J Immunol 2002; 169: 3232-3241. (Pubitemid 35013170)
28. Stassen M, Jonuleit H, Muller C, Klein M, Richter C, Bopp T, Schmitt S, Schmitt E: Differential regulatory capacity of CD25+ T regulatory cells and preactivated CD25+ T regulatory cells on development, functional activation, and proliferation of Th2 cells. J Immunol 2004; 173: 267-274. (Pubitemid 38797351)
29. van Wijk F, Wehrens EJ, Nierkens S, Boon L, Kasran A, Pieters R, Knippels LM: CD4+CD25+ T cells regulate the intensity of hypersensitivity responses to peanut, but are not decisive in the induction of oral sensitization. Clin Exp Allergy 2007; 37: 572-581. (Pubitemid 46537742)
30. Sasaki Y, Yoshimoto T, Maruyama H, Tegoshi T, Ohta N, Arizono N, Nakanishi K: IL-18 with IL-2 protects against Strongyloides venezuelensis infection by activating mucosal mast cell-dependent type 2 innate immunity. J Exp Med 2005; 202: 607-616. (Pubitemid 41248412)
31. Gri G, Piconese S, Frossi B, Manfroi V, Merluzzi S, Tripodo C, Viola A, Odom S, Rivera J, Colombo MP, Pucillo CE: CD4+CD25+ regulatory T cells suppress mast cell degranulation and allergic responses through OX40-OX40L interaction. Immunity 2008; 29: 771-781.
32. Kashyap M, Thornton AM, Norton SK, Barnstein B, Macey M, Brenzovich J, Shevach E, Leonard WJ, Ryan JJ: Cutting edge: CD4 T cell-mast cell interactions alter IgE receptor expression and signaling. J Immunol 2008; 180: 2039-2043.
33. Kennedy Norton S, Barnstein B, Brenzovich J, Bailey DP, Kashyap M, Speiran K, Ford J, Conrad D, Watowich S, Moralle MR, Kepley CL, Murray PJ, Ryan JJ: IL-10 suppresses mast cell IgE receptor expression and signaling in vitro and in vivo. J Immunol 2008; 180: 2848-2854.
34. Vocanson M, Rozieres A, Hennino A, Poyet G, Gaillard V, Renaudineau S, Achachi A, Benetiere J, Kaiserlian D, Dubois B, Nicolas JF: Inducible costimulator (ICOS) is a marker for highly suppressive antigen-specific T cells sharing features of Th17/Th1 and regulatory T cells. J Allergy Clin Immunol 2010;126:280-289.