Cutting edge: CD4 T cell-mast cell interactions alter IgE receptor expression and signaling

Journal of Immunology

Volumn 180, Issue 4, 2008, Pages 2039-2043

  Kashyap, Mohit ^a   Thornton, Angela M ^b   Norton, Sarah Kennedy ^a   Barnstein, Brian ^a   Macey, Matthew ^a   Brenzovich, Jennifer ^a   Shevach, Ethan ^b   Leonard, Warren J ^c   Ryan, John J ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN E; IMMUNOGLOBULIN E RECEPTOR; INTERLEUKIN 10; LEUKOTRIENE C4; STAT5 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; INTERLEUKIN 2 RECEPTOR ALPHA;

ANIMAL CELL; ANTIBODY PRODUCTION; ARTICLE; CD4+ T LYMPHOCYTE; CELL COMMUNICATION; CELL CONTACT; CELL INTERACTION; CELLULAR IMMUNITY; COCULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; IMMUNOMODULATION; LYMPHOCYTE CULTURE; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CELL MOTION; CYTOLOGY; DRUG ANTAGONISM; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; TRANSGENIC MOUSE;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELL COMMUNICATION; CELL MOVEMENT; CELLS, CULTURED; COCULTURE TECHNIQUES; GENE EXPRESSION REGULATION; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; MAST CELLS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; RECEPTORS, IGE; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY;

EID: 42149162890     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.180.4.2039     Document Type: Article

References (32)

1. Miescher, S. M., and M. Vogel. 2002. Molecular aspects of allergy. Mol. Aspects Med. 23: 413-462.
2. Secor, V. H., W. E. Secor, C. A. Gutekunst, and M. A. Brown. 2000. Mast cells are essential for early onset and severe disease in a murine model of multiple sclerosis. J. Exp. Med. 191: 813-822.
3. Levi-Schaffer, F., N. Riesel, D. Soffer, O. Abramsky, and T. Brenner. 1991. Mast cell activity in experimental allergic encephalomyelitis. Mol. Chem. Neuropathol. 15: 173-184.
4. Lee, D. M., D. S. Friend, M. F. Gurish, C. Benoist, D. Mathis, and M. B. Brenner. 2002. Mast cells: a cellular link between autoantibodies and inflammatory arthritis. Science 297: 1689-1692.
5. Malaviya, R., and S. N. Abraham. 2001. Mast cell modulation of immune responses to bacteria. Immunol. Rev. 179: 16-24.
6. Shevach, E. M. 2006. From vanilla to 28 flavors: multiple varieties of T regulatory cells. Immunity 25: 195-201.
7. + suppressor T cells. Immunol. Rev. 182: 58-67.
8. + T cell suppressor function. J. Immunol. 172: 6519-6523.
9. + T cells. J. Autoimmun. 16: 115-123.
10. + regulatory T cells control Leishmania major persistence and immunity. Nature 420: 502-507.
11. + regulatory T cells can mediate suppressor function in the absence of transforming growth factor β1 production and responsiveness. J. Exp. Med. 196: 237-246.
12. Prud'homme, G. J., and C. A. Piccirillo. 2000. The inhibitory effects of transforming growth factor-β-1 (TGF-β1) in autoimmune diseases. J. Autoimmun. 14: 23-42.
13. + regulatory T cells is mediated by cell surface-bound transforming growth factor β. J. Exp. Med. 194: 629-644.
14. Gregg, R. K., R. Jain, S. J. Schoenleber, R. Divekar, J. J. Bell, H. H. Lee, P. Yu, and H. Zaghouani. 2004. A sudden decline in active membrane-bound TGF-β impairs both T regulatory cell function and protection against autoimmune diabetes. J. Immunol. 173: 7308-7316.
15. Kashyap, M., D. Bailey, G. Gomez, J. Rivera, T. F. Huff, and J. J. Ryan. 2005. TGFβ1 inhibits mast cell development. Exp. Hematol. 33: 1281-1291.
16. Gomez, G., C. D. Ramirez, J. Rivera, M. Patel, F. Norozian, H. V. Wright, M. Kashyap, B. O. Barnstein, K. Fischer-Stenger, L. B. Schwartz, et al. 2005. TGFβ1 inhibits mast cell FcεRI Expression. J. Immunol. 174: 5987-5993.
17. Bouton, L. A., C. D. Ramirez, D. P. Bailey, C. F. Yeatman, J. Yue, H. V. Wright, J. Domen, R. R. Rosato, S. Grant, K. Fischer-Stenger, and J. J. Ryan. 2004. Co-stimulation with interleukin-4 and interleukin-10 induces mast cell apoptosis and cell cycle arrest: the role of p53 and the mitochondrion. Exp. Hematol. 32: 1137-1145.
18. Bailey, D. P., M. Kashyap, L. A. Bouton, P. J. Murray, and J. J. Ryan. 2006. Interleukin-10 induces apoptosis in developing mast cells and macrophages. J. Leukocyte Biol. 80: 689-694.
19. Gillespie, S. R., R. R. DeMartino, J. Zhu, H. J. Chong, C. D. Ramirez, C. P. Shelburne, L. A. Bouton, D. P. Bailey, A. Gharse, P. Mirmonsef, et al. 2004. IL-10 inhibits FcεRI expression in mouse mast cells. J. Immunol. 172: 3181-3188.
20. Chong, H. J., L. A. Bouton, D. P. Bailey, H. V. Wright, C. D. Ramirez, A. Gharse, C. Oskeritzian, H. Z. Xia, J. Zhu, W. E. Paul, et al. 2003. Differential regulation of mast cell FcγRII and FcγRIII by interleukin-4 and interleukin-10. Cell. Immunol. 224: 65-73.
21. Yeatman, C. F., II, S. M. Jacobs-Helber, P. Mirmonsef, S. R. Gillespie, L. A. Bouton, H. A. Collins, S. T. Sawyer, C. P. Shelburne, and J. J. Ryan. 2000. IL-4 and IL-10 induce apoptosis of murine bone marrow-derived mast cells. J. Exp. Med. 192: 1093-1103.
22. Mirmonsef, P., C. P. Shelburne, C. F. Yeatman, II, H. J. Chong, and J. J. Ryan. 1999. IL-4 and IL-10 inhibit c-Kit expression on mouse mast cells: role of Stat6 and PI-3 kinase. J. Immunol. 163: 2530-2539.
23. + regulatory T cells is interleukin 10 dependent. J. Exp. Med. 202: 1539-1547.
24. + T cells protect against experimentally induced asthma and alter pulmonary dendritic cell phenotype and function. J. Exp. Med. 202: 1549-1561.
25. Lu, L. F., E. F. Lind, D. C. Gondek, K. A. Bennett, M. W. Gleeson, K. Pino-Lagos, Z. A. Scott, A. J. Coyle, J. L. Reed, J. Van Snick, et al. 2006. Mast cells are essential intermediaries in regulatory T-cell tolerance. Nature 442: 997-1002.
26. Meiler, F., M. Zimmermann, K. Blaser, C. A. Akdis, and M. Akdis. 2006. T-cell subsets in the pathogenesis of human asthma. Curr. Allergy Asthma Rep. 6: 91-96.
27. Sayed, B. A., and M. A. Brown. 2007. Mast cells as modulators of T-cell responses. Immunol. Rev. 17: 53-64.
28. Dembo, M., B. Goldstein, A. K. Sobotka, and L. M. Lichtenstein. 1979. Degranulation of human basophils: quantitative analysis of histamine release and desensitization, due to a bivalent penicilloyl hapten. J. Immunol. 123: 1864-1872.
29. Shelburne, C. P., M. E. McCoy, R. Piekroz, V. Sexl, K. H. Roh, S. M. Jacobs-Helber, S. R. Gillespie, D. P. Bailey, P. Mirmonsef, M. N. Mann, et al. 2003. Stat5 expression is critical for mast cell development and survival. Blood 102: 1290-1297.
30. Barnstein, B. O., G. Li, Z. Wang, S. B. Kennedy, C. Chalfant, H. Nakajima, K. D. Bunting, and J. J. Ryan. 2006. Stat5 expression is required for IgE-mediated mast cell function. J. Immunol. 177: 3421-3426.
31. H2 cytokine production in an asthma model in mice. J. Allergy Clin. Immunol. 120: 48-55.
32. Mazzoni, A., R. P. Siraganian, C. A. Leifer, and D. M. Segal. 2006. Dendritic cell modulation by mast cells controls the Th1/Th2 balance in responding T cells. J. Immunol. 177: 3577-3581.