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Volumn 15, Issue 9, 2006, Pages 1401-1411

Polymorphism in the activity of human crossover hotspots independent of local DNA sequence variation

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOME 1Q; CONTROLLED STUDY; CROSSING OVER; DNA SEQUENCE; EPIGENETICS; GENETIC POLYMORPHISM; GENETIC RECOMBINATION; GENETIC VARIABILITY; HAPLOTYPE; HUMAN; HUMAN GENOME; MALE; PRIORITY JOURNAL; SPERM;

EID: 33646130166     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddl063     Document Type: Article
Times cited : (76)

References (41)
  • 3
    • 2142773942 scopus 로고    scopus 로고
    • The fine-scale structure of recombination rate variation in the human genome
    • McVean, G.A., Myers, S.R., Hunt, S., Deloukas, P., Bentley, D.R. and Donnelly, P. (2004) The fine-scale structure of recombination rate variation in the human genome. Science, 304, 581-584.
    • (2004) Science , vol.304 , pp. 581-584
    • McVean, G.A.1    Myers, S.R.2    Hunt, S.3    Deloukas, P.4    Bentley, D.R.5    Donnelly, P.6
  • 4
    • 26844482093 scopus 로고    scopus 로고
    • A fine-scale map of recombination rates and hotspots across the human genome
    • Myers, S., Bottolo, L., Freeman, C., McVean, G. and Donnelly, P. (2005) A fine-scale map of recombination rates and hotspots across the human genome. Science, 310, 321-324.
    • (2005) Science , vol.310 , pp. 321-324
    • Myers, S.1    Bottolo, L.2    Freeman, C.3    McVean, G.4    Donnelly, P.5
  • 6
    • 0034701292 scopus 로고    scopus 로고
    • High resolution analysis of haplotype diversity and meiotic crossover in the human TAP2 recombination hotspot
    • Jeffreys, A.J., Ritchie, A. and Neumann, R. (2000) High resolution analysis of haplotype diversity and meiotic crossover in the human TAP2 recombination hotspot. Hum. Mol. Genet., 9, 725-733.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 725-733
    • Jeffreys, A.J.1    Ritchie, A.2    Neumann, R.3
  • 7
    • 0034795550 scopus 로고    scopus 로고
    • Intensely punctate meiotic recombination in the class II region of the major histocompatibility complex
    • Jeffreys, A.J., Kauppi, L. and Neumann, R. (2001) Intensely punctate meiotic recombination in the class II region of the major histocompatibility complex. Nat. Genet., 29, 217-222.
    • (2001) Nat. Genet. , vol.29 , pp. 217-222
    • Jeffreys, A.J.1    Kauppi, L.2    Neumann, R.3
  • 8
    • 3042742130 scopus 로고    scopus 로고
    • Where the crossovers are: Recombination distributions in mammals
    • Kauppi, L., Jeffreys, A.J. and Keeney, S. (2004) Where the crossovers are: Recombination distributions in mammals. Nat. Rev. Genet., 5, 413-424.
    • (2004) Nat. Rev. Genet. , vol.5 , pp. 413-424
    • Kauppi, L.1    Jeffreys, A.J.2    Keeney, S.3
  • 9
    • 0036844238 scopus 로고    scopus 로고
    • Distribution of recombination crossovers and the origin of haplotype blocks: The interplay of population history, recombination, and mutation
    • Wang, N., Akey, J.M., Zhang, K., Chakraborty, R. and Jin, L. (2002) Distribution of recombination crossovers and the origin of haplotype blocks: The interplay of population history, recombination, and mutation. Am. J. Hum. Genet, 71, 1227-1234.
    • (2002) Am. J. Hum. Genet , vol.71 , pp. 1227-1234
    • Wang, N.1    Akey, J.M.2    Zhang, K.3    Chakraborty, R.4    Jin, L.5
  • 11
    • 0037932788 scopus 로고    scopus 로고
    • Randomly distributed crossovers may generate block-like patterns of linkage disequilibrium: An act of genetic drift
    • Zhang, K., Akey, J.M., Wang, N., Xiong, M., Chakraborty, R. and Jin, L. (2003) Randomly distributed crossovers may generate block-like patterns of linkage disequilibrium: An act of genetic drift. Hum. Genet., 113, 51-59.
    • (2003) Hum. Genet. , vol.113 , pp. 51-59
    • Zhang, K.1    Akey, J.M.2    Wang, N.3    Xiong, M.4    Chakraborty, R.5    Jin, L.6
  • 12
    • 3142736546 scopus 로고    scopus 로고
    • Haplotype diversity and SNP frequency dependence in the description of genetic variation
    • Stumpf, M.P. (2004) Haplotype diversity and SNP frequency dependence in the description of genetic variation. Eur. J. Hum. Genet., 12, 469-477.
    • (2004) Eur. J. Hum. Genet. , vol.12 , pp. 469-477
    • Stumpf, M.P.1
  • 13
    • 20044377420 scopus 로고    scopus 로고
    • Human recombination hot spots hidden in regions of strong marker association
    • Jeffreys, A.J., Neumann, R., Panayi, M., Myers, S. and Donnelly, P. (2005) Human recombination hot spots hidden in regions of strong marker association. Nat. Genet., 37, 601-606.
    • (2005) Nat. Genet. , vol.37 , pp. 601-606
    • Jeffreys, A.J.1    Neumann, R.2    Panayi, M.3    Myers, S.4    Donnelly, P.5
  • 14
    • 0036648248 scopus 로고    scopus 로고
    • Crossover clustering and rapid decay of linkage disequilibrium in the Xp/Yp pseudoautosomal gene SHOX
    • May, C.A., Shone, A.C., Kalaydjieva, L., Sajantila, A. and Jeffreys, A.J. (2002) Crossover clustering and rapid decay of linkage disequilibrium in the Xp/Yp pseudoautosomal gene SHOX. Nat. Genet., 31, 272-275.
    • (2002) Nat. Genet. , vol.31 , pp. 272-275
    • May, C.A.1    Shone, A.C.2    Kalaydjieva, L.3    Sajantila, A.4    Jeffreys, A.J.5
  • 15
    • 0842310835 scopus 로고    scopus 로고
    • Intense and highly localized gene conversion activity in human meiotic crossover hot spots
    • Jeffreys, A.J. and May, C.A. (2004) Intense and highly localized gene conversion activity in human meiotic crossover hot spots. Nat. Genet., 36, 151-156.
    • (2004) Nat. Genet. , vol.36 , pp. 151-156
    • Jeffreys, A.J.1    May, C.A.2
  • 16
    • 0346101497 scopus 로고    scopus 로고
    • Comparative linkage-disequilibrium analysis of the β-globin hotspot in primates
    • Wall, J.D., Frisse, L.A., Hudson, R.R. and Di Rienzo, A. (2003) Comparative linkage-disequilibrium analysis of the β-globin hotspot in primates. Am. J. Hum. Genet., 73, 1330-1340.
    • (2003) Am. J. Hum. Genet. , vol.73 , pp. 1330-1340
    • Wall, J.D.1    Frisse, L.A.2    Hudson, R.R.3    Di Rienzo, A.4
  • 20
    • 12244297072 scopus 로고    scopus 로고
    • Recombination hotspots rather than population history dominate linkage disequilibrium in the MHC class II region
    • Kauppi, L., Sajantila, A. and Jeffreys, A.J. (2003) Recombination hotspots rather than population history dominate linkage disequilibrium in the MHC class II region. Hum. Mol. Genet., 12, 33-44.
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 33-44
    • Kauppi, L.1    Sajantila, A.2    Jeffreys, A.J.3
  • 22
    • 0032133324 scopus 로고    scopus 로고
    • High-resolution mapping of crossovers in human sperm defines a minisatellite-associated recombination hotspot
    • Jeffreys, A.J., Murray, J. and Neumann, R. (1998) High-resolution mapping of crossovers in human sperm defines a minisatellite-associated recombination hotspot. Mol. Cell, 2, 267-273.
    • (1998) Mol. Cell , vol.2 , pp. 267-273
    • Jeffreys, A.J.1    Murray, J.2    Neumann, R.3
  • 23
    • 0036649022 scopus 로고    scopus 로고
    • Reciprocal crossover asymmetry and meiotic drive in a human recombination hot spot
    • Jeffreys, A.J. and Neumann, R. (2002) Reciprocal crossover asymmetry and meiotic drive in a human recombination hot spot. Nat. Genet., 31, 267-271.
    • (2002) Nat. Genet. , vol.31 , pp. 267-271
    • Jeffreys, A.J.1    Neumann, R.2
  • 24
    • 26444503776 scopus 로고    scopus 로고
    • Factors influencing recombination frequency and distribution in a human meiotic crossover hotspot
    • Jeffreys, A.J. and Neumann, R. (2005) Factors influencing recombination frequency and distribution in a human meiotic crossover hotspot. Hum. Mol. Genet., 14, 2277-2287.
    • (2005) Hum. Mol. Genet. , vol.14 , pp. 2277-2287
    • Jeffreys, A.J.1    Neumann, R.2
  • 25
    • 0030791317 scopus 로고    scopus 로고
    • The hotspot conversion paradox and the evolution of meiotic recombination
    • Boulton, A., Myers, R.S. and Redfield, R.J. (1997) The hotspot conversion paradox and the evolution of meiotic recombination. Proc. Natl Acad. Sci. USA, 94, 8058-8063.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 8058-8063
    • Boulton, A.1    Myers, R.S.2    Redfield, R.J.3
  • 26
    • 20444366133 scopus 로고    scopus 로고
    • Localized breakdown in linkage disequilibrium does not always predict sperm crossover hot spots in the human MHC class II region
    • Kauppi, L., Stumpf, M.P. and Jeffreys, A.J. (2005) Localized breakdown in linkage disequilibrium does not always predict sperm crossover hot spots in the human MHC class II region. Genomics, 86, 13-24.
    • (2005) Genomics , vol.86 , pp. 13-24
    • Kauppi, L.1    Stumpf, M.P.2    Jeffreys, A.J.3
  • 28
    • 0024476859 scopus 로고
    • An initiation site for meiotic gene conversion in the yeast Saccharomyces cerevisiae
    • Nicolas, A., Treco, D., Schultes, N.P. and Szostak, J.W. (1989) An initiation site for meiotic gene conversion in the yeast Saccharomyces cerevisiae. Nature, 338, 35-39.
    • (1989) Nature , vol.338 , pp. 35-39
    • Nicolas, A.1    Treco, D.2    Schultes, N.P.3    Szostak, J.W.4
  • 29
    • 0028273998 scopus 로고
    • Polarity of meiotic gene conversion in fungi: Contrasting views
    • Nicolas, A. and Petes, T.D. (1994) Polarity of meiotic gene conversion in fungi: Contrasting views. Experientia, 50, 242-252.
    • (1994) Experientia , vol.50 , pp. 242-252
    • Nicolas, A.1    Petes, T.D.2
  • 30
    • 0036783307 scopus 로고    scopus 로고
    • High-resolution patterns of meiotic recombination across the human major histocompatibility complex
    • Cullen, M., Perfetto, S.P., Klitz, W., Nelson, G. and Carrington, M. (2002) High-resolution patterns of meiotic recombination across the human major histocompatibility complex. Am. J. Hum. Genet., 71, 759-776.
    • (2002) Am. J. Hum. Genet. , vol.71 , pp. 759-776
    • Cullen, M.1    Perfetto, S.P.2    Klitz, W.3    Nelson, G.4    Carrington, M.5
  • 31
    • 18844419731 scopus 로고    scopus 로고
    • Persistence and loss of meiotic recombination hotspots
    • Pineda-Krch, M. and Redfield, R. (2005) Persistence and loss of meiotic recombination hotspots. Genetics, 169, 2319-2333.
    • (2005) Genetics , vol.169 , pp. 2319-2333
    • Pineda-Krch, M.1    Redfield, R.2
  • 32
    • 0025974980 scopus 로고
    • Genetic control of sex-dependent meiotic recombination in the major histocompatibility complex of the mouse
    • Shiroishi, T., Sagai, T., Hanzawa, N., Gotoh, H. and Moriwaki, K. (1991) Genetic control of sex-dependent meiotic recombination in the major histocompatibility complex of the mouse. EMBO J., 10, 681-686.
    • (1991) EMBO J. , vol.10 , pp. 681-686
    • Shiroishi, T.1    Sagai, T.2    Hanzawa, N.3    Gotoh, H.4    Moriwaki, K.5
  • 33
    • 0027938045 scopus 로고
    • Changes in chromatin structure at recombination initiation sites during yeast meiosis
    • Ohta, K., Shibata, T. and Nicolas, A. (1994) Changes in chromatin structure at recombination initiation sites during yeast meiosis. EMBO J., 13, 5754-5763.
    • (1994) EMBO J. , vol.13 , pp. 5754-5763
    • Ohta, K.1    Shibata, T.2    Nicolas, A.3
  • 34
    • 0028206864 scopus 로고
    • Meiosis-induced double-strand break sites determined by yeast chromatin structure
    • Wu, T.C. and Lichten, M. (1994) Meiosis-induced double-strand break sites determined by yeast chromatin structure. Science, 263, 515-518.
    • (1994) Science , vol.263 , pp. 515-518
    • Wu, T.C.1    Lichten, M.2
  • 35
    • 0029862606 scopus 로고    scopus 로고
    • Relationship between nuclease-hypersensitive sites and meiotic recombination hot spot activity at the HIS4 locus of Saccharomyces cerevisiae
    • Fan, Q.Q. and Petes, T.D. (1996) Relationship between nuclease-hypersensitive sites and meiotic recombination hot spot activity at the HIS4 locus of Saccharomyces cerevisiae. Mol. Cell. Biol., 16, 2037-2043.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2037-2043
    • Fan, Q.Q.1    Petes, T.D.2
  • 36
    • 0035874481 scopus 로고    scopus 로고
    • The marks, mechanisms and memory of epigenetic states in mammals
    • Rakyan, V.K., Preis, J., Morgan, H.D. and Whitelaw, E. (2001) The marks, mechanisms and memory of epigenetic states in mammals. Biochem. J., 356, 1-10.
    • (2001) Biochem. J. , vol.356 , pp. 1-10
    • Rakyan, V.K.1    Preis, J.2    Morgan, H.D.3    Whitelaw, E.4
  • 37
    • 0024672869 scopus 로고
    • Mutations, epimutations, and the developmental programming of the maize suppressor-mutator transposable element
    • Fedoroff, N., Masson, P. and Banks, J.A. (1989) Mutations, epimutations, and the developmental programming of the maize suppressor-mutator transposable element. Bioessays, 10, 139-144.
    • (1989) Bioessays , vol.10 , pp. 139-144
    • Fedoroff, N.1    Masson, P.2    Banks, J.A.3
  • 38
    • 0033539183 scopus 로고    scopus 로고
    • An epigenetic mutation responsible for natural variation in floral symmetry
    • Cubas, P., Vincent, C. and Coen, E. (1999) An epigenetic mutation responsible for natural variation in floral symmetry. Nature, 401, 157-161.
    • (1999) Nature , vol.401 , pp. 157-161
    • Cubas, P.1    Vincent, C.2    Coen, E.3
  • 39
    • 2442424419 scopus 로고    scopus 로고
    • Germline epimutation of MLH1 in individuals with multiple cancers
    • Suter, C.M., Martin, D.I. and Ward, R.L. (2004) Germline epimutation of MLH1 in individuals with multiple cancers. Nat. Genet., 36, 497-501.
    • (2004) Nat. Genet. , vol.36 , pp. 497-501
    • Suter, C.M.1    Martin, D.I.2    Ward, R.L.3
  • 40
    • 0015862142 scopus 로고
    • The age of a neutral mutant persisting in a finite population
    • Kimura, M. and Ota, T. (1973) The age of a neutral mutant persisting in a finite population. Genetics, 75, 199-212.
    • (1973) Genetics , vol.75 , pp. 199-212
    • Kimura, M.1    Ota, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.